Prospective neurobiological effects of the aerial and root extracts and some pure compounds of randomly selectedScorzoneraspecies

2014 ◽  
Vol 52 (7) ◽  
pp. 873-882 ◽  
Author(s):  
F. Sezer Senol ◽  
Ozlem Bahadir Acikara ◽  
Gulcin Saltan Citoglu ◽  
Ilkay Erdogan Orhan ◽  
Stefano Dall’ Acqua ◽  
...  
Keyword(s):  
Root Extracts ◽  
Pure Compounds

scholarly journals Rewarding compounds identified from the medicinal plant Rhodiola rosea

2020 ◽  
Vol 223 (16) ◽  
pp. jeb223982
Author(s):  
Birgit Michels ◽  
Katrin Franke ◽  
Aliće Weiglein ◽  
Haider Sultani ◽  
Bertram Gerber ◽  
...  
Keyword(s):  
Dopamine Neurons ◽  
Rhodiola Rosea ◽  
Rewarding Effect ◽  
Root Extracts ◽  
Pure Compounds ◽  
Chemical Profiles ◽  
Nervous System Function ◽  
Positive Correlations ◽  
Behavioral Impact ◽  
Addictive Potential

ABSTRACTPreparations of Rhodiola rosea root are widely used in traditional medicine. They can increase life span in worms and flies, and have various effects related to nervous system function in different animal species and humans. However, which of the compounds in R. rosea is mediating any one of these effects has remained unknown in most cases. Here, an analysis of the volatile and non-volatile low-molecular-weight constituents of R. rosea root samples was accompanied by an investigation of their behavioral impact on Drosophila melanogaster larvae. Rhodiola rosea root samples have an attractive smell and taste to the larvae, and exert a rewarding effect. This rewarding effect was also observed for R. rosea root extracts, and did not require activity of dopamine neurons that mediate known rewards such as sugar. Based on the chemical profiles of R. rosea root extracts and resultant fractions, a bioactivity-correlation analysis (AcorA) was performed to identify candidate rewarding compounds. This suggested positive correlations for – among related compounds – ferulic acid eicosyl ester (FAE-20) and β-sitosterol glucoside. A validation using these as pure compounds confirmed that the correlations were causal. Their rewarding effects can be observed even at low micromolar concentrations and thus at remarkably lower doses than for any known taste reward in the larva. We discuss whether similar rewarding effects, should they be observed in humans, would indicate a habit-forming or addictive potential.

Phenolic profile and antioxidant activity of buckwheat (Fagopyrum esculentum) herb and root extracts

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
D Orcic ◽  
E Svirčev ◽  
N Mimica-Dukic ◽  
I Beara ◽  
K Balog ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Fagopyrum Esculentum ◽  
Phenolic Profile ◽  
Root Extracts

Antioxidative properties of pure compounds and phytogenic feed additives in a chemical (ORAC) and a cell-based assay (yeast)

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
K Teichmann ◽  
D Wendner ◽  
D Bachinger ◽  
S Hessenberger ◽  
G Schatzmayr
Keyword(s):  
Feed Additives ◽  
Antioxidative Properties ◽  
Pure Compounds ◽  
A Cell

Invivo Activity of Polyherbal Gels Prepared Using Carbopol

2020 ◽  
Vol 10 (3) ◽  
pp. 63-66
Author(s):  
Parasakthi N ◽  
Deepika R ◽  
Sivanathan C ◽  
Abubackkar Sithiq PD ◽  
Venkateshan N
Keyword(s):  
Physiological Stress ◽  
Defense Responses ◽  
The Body ◽  
Peptic Ulcers ◽  
Onset Of Action ◽  
Standard Drug ◽  
Root Extracts ◽  
Carbopol 940 ◽  
Anti Inflammatory ◽  
Rich Countries

Pain and inflammation are the basic defense responses of the body that the result of the injury and any other damage to the body. During the years the concerns were raised towards the inflammation that is caused to the oxidative damage that is resulted in the physiological stress due to oxidation. There are a lot of drugs that are used to treat the condition effectively and the typical examples are NSAID’s and SAID’s which have a noted mechanism to show the anti-inflammatory activity. They have serious problems with the side effects like Gastrointestinal irritation, Gastric pain, Gastric perforations and peptic ulcers. Herbs have been used as better alternatives that are used to treat diseases. The significance of the medicinal plants had been emphasized significantly in tradition rich countries like India and all over the world. The research proof of those herbs for their activities and their traditional claims were proven. Poly Herbal Gels were prepared using the root extracts of the plant Corchorus olitorius. The gels were prepared using the Carbopol 940 and the prepared gels were investigated for their anti-inflammatory property and the gels showed a significantly better activity compared to the plant extract and the standard drug too. The addition of other drugs in to the gels added and advantage to the increase in the activity and faster onset of action as the gel was applied directly in the place of the inflammation.

Antipyretic Activity of the Root Extracts of Xylocarpus

2019 ◽  
Vol 9 (3) ◽  
pp. 35-38
Author(s):  
Ganesh Kumar Y ◽  
Pranitha D ◽  
Phaneendra D ◽  
Madhava Reddy Ch
Keyword(s):  
Mechanisms Of Action ◽  
Prostaglandin Synthesis ◽  
The Body ◽  
Human Race ◽  
Pharmacological Activities ◽  
Standard Drug ◽  
Root Extracts ◽  
Antipyretic Activity ◽  
Inhibition Of Prostaglandin Synthesis ◽  
Elevated Body Temperature

Various types of conditions exist in the body that causes fever and pain. Drugs that are used to treat fever are called antipyretics, and those are usually prescribed to treat elevated body temperature. But those drugs result in many other side effects like ulcers, perforations, bleedings and obstructions, which make their use questionable and limiting. Medicinal plants are used in the treatment of diseases from the starting of the human race and the process; they had been subjected to rigorous investigations and tests to establish a scientific proof and validation of the various pharmacological activities and their respective mechanisms of action in treating the herbs. Considering the anti-inflammatory properties of the plant, Xylocarpus mekongesis was investigated for its antipyretic activity in yeast method and 3doses out of which 00mg/kg body weight showed a better activity compared to the standard drug and other extracts too. The mechanism of action was similar to the paracetamol action that is inhibition of prostaglandin synthesis.

Antipyretic activity of the root extracts of Desmodium Gangeticum

2018 ◽  
Vol 8 (2) ◽  
pp. 20-23
Author(s):  
Raja Sheker K ◽  
Naveen B ◽  
Anil kumar A ◽  
Abhilash G
Keyword(s):  
Gastric Ulcers ◽  
Plant Leaves ◽  
Medical Systems ◽  
Human Race ◽  
Standard Drug ◽  
Root Extracts ◽  
Antipyretic Activity ◽  
Scientific Investigations ◽  
And Control ◽  
Effective Drugs

Fevers are considered as the most important parameters to evaluate and diagnose most of the disease conditions like inflammations, wounds and other infections. There are effective drugs that treat and control the fevers out of which NSAID's are most important ones. They cause notable side effects like gastric ulcers, gastric mucosal perforations etc. which make the use of those drugs limited. Herbs are used to treat various diseases, starting from the evolution of the human race. During this, herbs had been introduced to many types of tests and scientific investigations to prove the activities that herbs possess. The diseases that the herbs are used for are notable in the medical systems like Ayurveda and other systems. The need for the validation of the activities of the herbs and medicinal plants is utmost important these days. The extracts of the plant leaves of Desmodium gangeticum were extracted with ethanol and then investigated for the antipyretic activity in yeast induced pyretic method. The extract was tested in two doses 200 and 400mg/kg. This was found significant when compared to the standard drug.

Herbicidal potential of Aerva javanica to control wild oat in wheat crop

2020 ◽  
Vol 51 (2) ◽  
pp. 177-194
Author(s):  
Al-Ghamdi A.M. ◽  
El-Zohri M
Keyword(s):  
Dry Weight ◽  
Soluble Carbohydrates ◽  
Wheat Crop ◽  
Aqueous Extracts ◽  
Wild Oat ◽  
Culture Experiment ◽  
Allelopathic Potential ◽  
Root Extracts ◽  
Wheat Germination ◽  
Radical Length

We investigated the phytotoxicity of desert cotton (Aerva javanica) extracts on wild oat and wheat. Aqueous extracts from A. javanica roots, leaves and inflorescences collected from Jeddah and Al-Baha regions, Saudi Arabia were used. Generally, the allelopathic potential of water extracts of A. javanica collected from Jeddah were more in inhibitory to wild oat germination and seedlings growth than those from Al-Baha. In both regions, root extracts were inhibitory to wild oat followed by leaves and inflorescences extracts. All test aqueous extracts of both regions did not inhibit the wheat germination or seedlings growth.Whreas, the wild oat germination was reduced by root extracts 58.62 %, 28.62 % leaves extracts : 32.72 %, 17.72 % and inflorescences extract 28.11 %, 12.13 % by in plants samples collected from Jeddah and Al-Baha, respectively. Wild oat radical length was inhibited by root extracts 53.27 %, 32.84 % leaves 42.35 %, 9.63 % and inflorescences extracts 22.64 %, 16.75 % in case of Jeddah and Al-Baha plants, respectively. In pot culture experiment, all treatments markedly reduced the plant dry weight and soluble carbohydrates, proteins and free amino acids contents in wild oat. The differences in the allelopathic potentials of studied A. javanica extracts were related to the qualitative variations in their phytochemicals constituents. Our results showed that A. javanica extracts could be safely used to control wild oat growth in wheat fields after more detsaled research..

Sign in / Sign up

Export Citation Format

Share Document