scholarly journals Colorectal bradyarrhythmia syndrome as a predictor of metabolic syndrome

2020 ◽  
Vol 183 (11) ◽  
pp. 44-50
Author(s):  
K. A. Shemerovskii ◽  
V. N. Fedorets ◽  
P. V. Seliverstov ◽  
S. R. Bakaeva
Keyword(s):  
Metabolic Syndrome ◽  
Well Being ◽  
Medical Professionals ◽  
Early Prevention ◽  
The Third ◽  
The Metabolic Syndrome ◽  
Severe Stage ◽  
Order Of Magnitude ◽  
Two Stages

Evidence is presented for a significantly wider spread of the first two stages (mild and moderate) Colorectal Bradyarrhythmia Syndrome (CBS) compared with the third (severe — constipation) stage of this syndrome. Surveyed more than 2,500 medical professionals by the method of chronoenterographia. It was found that the incidence of mild CBS (about 60% of cases) and moderate stage of this syndrome (about 30% of cases) is almost an order of magnitude higher than the incidence of severe stage (about 10% of cases) of CBS. SCB has been shown to increase the risk of obesity by almost 3 times. It is shown that CBS contributes to a decrease in well-being, activity and mood, as well as a decrease in the quality of life. Screening for CBS and normalizing the circadian bowel rhythm with psyllium (mucofalc) in individuals who consider themselves healthy may contribute to early prevention of the risk of the metabolic syndrome.

ARTERIAL HYPERTENSION AND COMORBIDITY (REVIEW)

2020 ◽  
Vol 2 (1) ◽  
pp. 9-13
Author(s):  
Irina Agababyan ◽  
◽  
Shukhrat Ziyadullaev ◽  
Jamshid Ismailov
Keyword(s):  
Quality Of Life ◽  
Metabolic Syndrome ◽  
Arterial Hypertension ◽  
The Metabolic Syndrome

Today, hypertension is considered by many authors within the framework of the manifestation of the metabolic syndrome. It has been established that in persons with hypertension in 60% of cases, various variants of MS are found. In addition, hypertension is a factor that reduces the quality of life of patients, especially those with comorbid pathology

scholarly journals Inclusion and Integration of the Disabled into the Labor Market Against the Background of the New Regulations in Germany

Equilibrium ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. 79-101
Author(s):  
Lilianna Jodkowska
Keyword(s):  
Labor Market ◽  
Quality Management System ◽  
The Third ◽  
The Social ◽  
The Disabled ◽  
Social Code ◽  
Two Stages ◽  
The Unemployed ◽  
New Criteria

The aim of the article is to present new regulations introduced by the Third Book of the Social Code in Germany that concern a reform of the labor market's active instruments gathered under the name "Instumentenreform".  One of the main objectives of the reform is to improve the quality of programs and projects that activate the unemployed, but also to make efforts to include in the labor market groups that have not been activated in such a way so far. One of such groups are the disabled trained and employed in Invalids' Cooperatives.  One of the further, and at the same time new, criteria for all organizations and institutions receiving and applying for funds to realize programs of the labor market and vocational trainings is the introduction and certification of the quality management system. The aim of the paper is to compare the activity of Invalids' Cooperatives in Poland and Germany. This aim will be carried out by analyzing the regulations and as far as possible the data available (the regulations became effective in two stages: in April 2012, and since 01.01.2013 onwards).  The findings of the article have been collected in the form of a description of the situation and forecast for 2013.

scholarly journals Quality of Life and Metabolic Syndrome in Brazilian quilombola communities: A Crosssectional Study

2018 ◽  
Vol 28 (3) ◽  
pp. 316-328
Author(s):  
Luiz Vinicius De Alcantara Sousa ◽  
Erika Da Silva Maciel ◽  
Fernando Rodrigues Peixoto Quaresma ◽  
Ana Carolina Gonçalves de Abreu ◽  
Laércio Da Silva Paiva ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Metabolic Syndrome ◽  
Fasting Blood Glucose ◽  
Clinical Aspects ◽  
Inverse Association ◽  
Male Population ◽  
Female Population ◽  
The Metabolic Syndrome ◽  
Abdominal Perimeter

Introduction: The lifestyle of quilombola communities has changed due to extra community influence, thus affecting their environmental and behavioral factors related to the Metabolic Syndrome (MS). However, little is known about the influence of MS on the Quality of Life (QoL) of quilombola residents. Objective: We aimed to study the association between MS and QoL in quilombola communities in northern Tocantins, Brazil. Methods: The QoL of 147 adults from five quilombola communities from Tocantins was assessed using the WHOQOL-BREF instrument. Blood pressure, abdominal perimeter, fasting blood glucose, triglycerides and HDL-cholesterol were measured, and the presence of MS was defined as the alteration of at least three of these clinical aspects. The association of the clinical components and the SM presence with the Quality of Life was evaluated by Student’s t-test for independent samples. Results: We observed that in the total population, an altered abdominal perimeter had an inverse association with both the Physical (15.2 vs. 14.0, p=0.002) and General QoL domains (14.4 vs. 14.0, p=0.045), and MS was inversely associated with the Physical domain (14.9 vs. 14.0, p=0.030). When stratified by sex, the altered abdominal perimeters in men were inversely associated with the Physical (16.5 vs. 14.4, p<0.001), Environmental (14.0 vs. 12.6, p=0.020) and General domains (15.5 vs. 14.0, p<0.001). MS had an inverse association with the Physical (15.8 vs. 14.4, p=0.026) and General domains (14.8 vs. 14.0 p= 0.042) in men. In women there was no association between any risk factor studied and QoL domain. Conclusions: The status of MS was negatively associated with the quality of life of the male population, highlighting the abdominal perimeter, which influences the Physical and General domains of QoL, but in the female population the MS does not interfere in the perception of QoL. Understanding the relationship between chronic diseases and QoL in quilombola communities is necessary to reduce health inequalities in historically vulnerable communities.  

Abstract 3203: The role of Neprilysin in the Development of Insulin Resistance, Type 2 Diabetes and Cardiovascular Disease

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Kristina F Standeven ◽  
Angela M Carter ◽  
Anthony J Balmforth ◽  
Stephen B Wheatcroft ◽  
Nigel M Hooper ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Vascular Function ◽  
Animal Studies ◽  
Obese Mice ◽  
Human Adipocytes ◽  
The Metabolic Syndrome ◽  
Mesenteric Fat ◽  
Order Of Magnitude ◽  
Average Gene

Neprilysin (NEP) cleaves several bioactive peptides involved in the regulation of vascular function. In human microvascular endothelial cells, fatty acids and glucose increase NEP activity, and inhibition of NEP in animal studies results in increased insulin sensitivity, suggesting that NEP may be related to the metabolic syndrome. We tested this hypothesis in cell, animal and human based models. Microarray analysis of mRNA expression in differentiated human adipocytes (Affymetrix Human Genome U133 Plus 2.0 arrays) showed NEP expression to be an order of magnitude higher than the average gene signal, suggesting that human adipocytes express high endogenous levels of NEP mRNA. Real time PCR confirmed high levels of NEP mRNA in preadipocytes which increased 28 fold during differentiation and reached levels equivalent to the endogenous control, GAPDH, by 14 days. We created a diet induced model of obesity by feeding male C57BL/6J mice a high-fat diet, which resulted in decreased glucose tolerance and insulin resistance in obese mice. Plasma NEP levels measured after 15 weeks of feeding were significantly higher in obese mice (1642 [± 529]) pg/μl) compared to lean mice (820 [± 487] pg/μl) (p < 0.01). NEP levels increased 4- and 9-fold in epididymal and mesenteric fat in obese, compared to lean, mice. In a study of 318 healthy white European males, plasma NEP measured by activity assay was significantly higher in subjects with the metabolic syndrome (MetS) and levels increased progressively with increasing number of MetS components, being ~8-fold higher in those with 5 MetS components compared with those with none. NEP correlated with insulin, HOMA and BMI in all subjects. In conclusion, we have generated cell, murine and human data which suggest that NEP may have an important role in cardio-metabolic risk associated with insulin resistance, with the adipocyte as a major source of NEP. These findings indicate that NEP is a novel adipokine that links insulin resistance to vascular risk.

scholarly journals Prevalence of Metabolic Syndrome and Its Components in Adults with Central Obesity at Janakpur Zone, Nepal

2021 ◽  
Vol 18 (4) ◽  
pp. 681-685
Author(s):  
Birendra Kumar Jha ◽  
Mingma Lhamu Sherpa ◽  
Binod Kumar Dahal ◽  
Jitendra Kumar Singh
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Central Obesity ◽  
International Diabetes Federation ◽  
Cross Sectional Study ◽  
High Density Lipoproteins ◽  
Cluster Sampling ◽  
Cross Sectional ◽  
The Metabolic Syndrome

Background: Urbanization, surplus energy uptake, decreased physical activities are general risk factors of metabolic syndrome However, it’s status, and associated components remain unexplored in the Terai region of Nepal. This study evaluated the prevalence of metabolic syndrome and its components among adults with central obesity of Terai region of Nepal using International Diabetes Federation criteria.Methods: Community based cross-sectional study was conducted in three Terai districts of Janakpur Zone, Nepal. A total of 378 adults having central obesity were selected using cluster sampling by camp approach. Interview, physical and clinical examination, measurement of fasting blood sugar, and lipid profile were conducted for all participants. The prevalence of metabolic syndrome and its components with 95% CI were estimated.Results: The metabolic syndrome prevalence was 74.9% (95% CI:70.2-79.2%), with no significant differences between male (77.7%, 95% CI:71.0-83.5%) and female (72.2%, 95% CI: 65.2-78.3%). The most common factors observed were low high density lipoproteins with highly significant differences between male (77.7%, 95% CI:71.0-83.5%)) and female (90.2%, 95% CI: 85.094.0%-; p=0.001) and hypertriglyceridemia with significant differences between male (57.6%, 95% CI: 50.1-64.5%) and female (46.9%, 95% CI: 39.7-54.2%; p=0.037). Conclusions: Higher prevalence of metabolic syndrome and its risk factors in Janakpur of Nepal likely suggest lack of awareness and health promotion activities for metabolic syndrome and indicate an urgency for a public health program to maintain quality of life. Keywords: Metabolic syndrome; Nepal; prevalence; risk factors; terai

scholarly journals Sex and Age Differences in Levels of Anomia of Latvian Inhabitants

2015 ◽  
Vol 3 ◽  
pp. 567 ◽  
Author(s):  
Jeļena Ļevina ◽  
Kristīne Mārtinsone ◽  
Daiga Kamerāde
Keyword(s):  
Quality Of Life ◽  
Age Differences ◽  
Age Groups ◽  
Secondary Data ◽  
Well Being ◽  
Demographic Groups ◽  
The Third ◽  
Significant Difference ◽  
Sex And Age Differences

<p><em>Anomia is one of the important factors, which can influence the psychological well-being of individuals. It is especially valuable to determine those socio-demographic groups which can demonstrate the highest levels of anomia. The purpose of the research was to determine whether there are sex and age differences in levels of anomia of Latvian inhabitants. The secondary data from the third European Quality of Life Survey (EQLS) were used. The sample consisted of Latvian inhabitants (n = 1009), aged from 18 to 92 years (male – 34.9%, female – 65.1%). 3 indices and 3 subscales of anomia (Social Distrust, Social Isolation and Meaninglessness) were constructed (</em><em>Ļevina, Mārtinsone &amp; </em><em>Kamerāde, 2015a, 2015b). </em><em>A multivariate analysis of variance was conducted. It was found that there was a significant difference in multidimensional anomia between Latvian inhabitants of different age groups.</em></p><p> </p>

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