scholarly journals Quantitative analysis of repaired and unrepaired damage to trilobites from the Cambrian (Stage 4 - Drumian) Iberian Chains, NE Spain

2018 ◽  
Author(s):  
Stephen Pates ◽  
Russell DC Bicknell ◽  
Allison C. Daley ◽  
Samuel Zamora
Keyword(s):  
Process Analysis ◽  
Healing Process ◽  
Ecological Interactions ◽  
Deep Time ◽  
Formation Stage ◽  
Weak Evidence ◽  
Stage 4 ◽  
Repair Mechanisms ◽  
Long Time ◽  
Selection For

Repaired fossil skeletons provide the opportunity to study predation rates, repair mechanisms, and ecological interactions in deep time. Trilobites allow the study of repaired damage over long time periods and large geographic areas due to their longevity as a group, global distribution, and well-preserved mineralized exoskeletons. Repair frequencies on trilobites from three sites representing offshore marine environments in the Iberian Chains (Spain) show no injuries on 45 complete redlichiid thoraces from Minas Tierga (Huérmeda Formation, Cambrian Series 2, Stage 4), or 23 complete Eccaparadoxides pradoanus thoraces from Mesones de Isuela (Murero Formation, Cambrian Series 3, Drumian). Ten injuries on 69 E. pradoanus thoraces from Purujosa (Murero Formation, Cambrian Series 3, Drumian) were noted. There is no evidence for laterally asymmetric predation or size selection on the trilobites in this study. Weak evidence for selection for the rear of the thorax is documented. A series of injured trilobites illustrates four stages of the healing process. Analysis of injury locations and frequency suggests that injuries to these trilobites are predatory in origin. Semilandmark analysis of previously described exoskeletons with unrepaired damage assigned to the ichnotaxon Bicrescomanducator serratus alongside newly collected damaged exoskeletons from Purujosa (Mansilla and Murero Formations, Stage 5, Drumian), Mesones de Isuela (Murero Formation, Drumian), and Minas Tierga (Huérmeda Formation, Stage 4) found that shapes of biotic and abiotic breaks could not be distinguished.

scholarly journals The fat anchor orchiopexy technique: results and outcomes from 150 cases surgical experience

2021 ◽  
Author(s):  
Claudio Spinelli ◽  
Alessia Bertocchini ◽  
Gianmartin Cito ◽  
Marco Ghionzoli ◽  
Silvia Strambi
Keyword(s):  
Undescended Testis ◽  
Healing Process ◽  
Day Surgery ◽  
Post Surgery ◽  
Post Operative Pain ◽  
Surgical Wounds ◽  
Bilateral Cryptorchidism ◽  
Long Time ◽  
History Of

Abstract Purpose The purpose of the study is to evaluate results and outcomes in a long-time follow-up period, by performing a novel testicular fixation procedure, known as “fat anchor orchidopexy” (FAO), for the treatment of palpable low inguinal undescended testis. Materials and methods We retrospectively reviewed all patients who underwent scrotal orchiopexy technique, from May 2013 to May 2019, at the Pediatric Surgery Division of Department of Surgical Pathology, University of Pisa (Italy). FAO (Spinelli’s technique) consists in anchoring the testicles to sub-scrotal fat with a single trans-scrotal incision. All the patients enrolled had history of unilateral or bilateral undescended testis. Data collected included patient’s age, operative times and complications. Results A total of 150 children with cryptorchidism were treated using a single trans-scrotal orchiopexy. Of them, 130 patients (86.7%) had unilateral undescended testis and 20 (13.3%) bilateral cryptorchidism. Mean patient’s age was 21 months (range: 14–28 months). All the procedures were planned in a day-surgery setting. Trans-scrotal orchiopexy was successful in all cases and no patients required an additional groin incision. No intraoperatively and postoperatively major complications were observed. Patients’ post-operative pain was mild (mean pediatric visual analog scale = 2). In all cases, the healing process was rapid and no surgical wounds infections were reported during the post-operative period, referring excellent cosmesis results. During a mean 48-month follow-up period, no testicular retraction, recurrence or testis atrophy was reported. Conclusion The original Spinelli’s technique (FAO) proves to be a safe and effective method for the treatment of palpable or distal-to-external-inguinal-ring testes. No immediate and delayed post-surgery complications were reported. In all cases, the anchored testicle remained in the scrotal position with normal vascularization. This novel surgical technique could give better options for scrotal fixation in case of low-lying cryptorchid testes.

A renewed look at silver dressings for wound infections: Ag Oxysalts technology

2021 ◽  
Vol 26 (Sup9) ◽  
pp. S26-S36
Author(s):  
Luxmi Dhoonmoon ◽  
Hayley Turner-Dobbin ◽  
Karen Staines
Keyword(s):  
Wound Healing ◽  
Wound Infection ◽  
Case Studies ◽  
Healing Process ◽  
Systemic Toxicity ◽  
Wound Healing Process ◽  
Wound Infections ◽  
Infected Wounds ◽  
Long Time

Wound infection is an important complicating factor in the wound healing process, and infections can be even more complex and difficult to manage in the case of wounds with biofilms. Silver has been used to treat infected wounds for a long time now, and the strength of the product depends on the number of Ag ions, where the greater the number of ions, the higher and faster the reactivity is. Ag Oxysalts technology—used in 3M Kerracontact Ag dressing—has three times more ions than standard silver dressings. The technology also does not show the typical disadvantages of silver, such as cytotoxicity and systemic toxicity. This article discusses the use of Ag Oxysalts technology for infected wounds and presents case studies to support the efficacy of this product in promoting wound healing.

scholarly journals USIA DAN BUDAYA PANTANGMAKANAN MEMPENGARUHI PENYEMBUHAN LUKA PERINEUM PADA IBU NIFAS HARI KE 7

2015 ◽  
Vol 6 (2) ◽  
Author(s):  
Sondang Sidabutar
Keyword(s):  
Wound Healing ◽  
Wound Care ◽  
Healing Process ◽  
Sampling Technique ◽  
Perineal Wound ◽  
Wound Healing Process ◽  
Birth Canal ◽  
Perineal Wound Healing ◽  
Health Officer ◽  
Long Time

Wound healing is a long time in there covery process because of damage to the skin or skin tissue disintegritas. According to Rustam Mochtar(1998), the injured in the birth canal when not accompanied by infection will heal within6-7days. Based on the results of a survey on BPS Ny. Arifin S. Surabaya, from as many as7 of 10 respondents (70%) found the wound is still wet. The purpose of this study was to determine age and cultural picture of incontinence on postpartum mother's perineal wound healing on the seventh day in the BPS Ny. Arifin S. Surabaya. In this research using descriptive method with the study population was all mothers with post natal on the seventh day stit chesin the perineum which controls BPS Ny. Arifin S. Surabaya period from July to August 2008 as many as 49 people. Sampling of non-probability sampling with a sampling technique is saturated. By using questionnaires and observation sheets as research instruments. Data created frequency tables and cross tabulations and then summed. Based on the results of research on maternal postnatal day 9 to 7, obtained the majority of postnatal mother saged <35 years of the perineal wound healed as many as 24 people (66.66%) and in postpartum mothers who do not abstain from the majority of the perineal wound healed as many as17 people (77.27%). By looking at these result it can be concluded that the perineal wound healing can be influenced byculture age and abstinence from food. Therefore, the provision of good information and right by the health officer of the perineal wound care will affect the success of the perineal wound healing process.

A thermodynamic limit constrains complexity and primitive social function

2018 ◽  
Vol 18 (4) ◽  
pp. 329-335
Author(s):  
Philip J Gerrish ◽  
Claudia P Ferreira
Keyword(s):  
Mutation Rate ◽  
Social Behaviour ◽  
Social Function ◽  
Somatic Tissue ◽  
Transformation Rate ◽  
Complex Societies ◽  
Evolutionary Trend ◽  
Extraterrestrial Life ◽  
Repair Mechanisms ◽  
Selection For

AbstractThe evolutionary trend toward increasing complexity and social function is ultimately the result of natural selection's paradoxical tendency to foster cooperation through competition. Cooperating populations ranging from complex societies to somatic tissue are constantly under attack, however, by non-cooperating mutants or transformants, called ‘cheaters’. Structure in these populations promotes the formation of cooperating clusters whose competitive superiority can alone be sufficient to thwart outgrowths of cheaters and thereby maintain cooperation. But we find that when cheaters appear too frequently – exceeding a threshold mutation or transformation rate – their scattered outgrowths infiltrate and break up cooperating clusters, resulting in a cascading loss of social cohesiveness, a switch to net positive selection for cheaters and ultimately in the loss of cooperation. Our findings imply that a critically low mutation rate had to be achieved (perhaps through the advent of proofreading and repair mechanisms) before complex cooperative functions, such as those required for multicellularity and social behaviour, could have evolved and persisted. When mutation rate in our model is also allowed to evolve, the threshold is crossed spontaneously after thousands of generations, at which point cheaters rapidly invade. Probing extrapolations of these findings suggest: (1) in somatic tissue, it is neither social retro-evolution alone nor mutation rate evolution alone but the interplay between these two that ultimately leads to oncogenic transitions; the rate of this coevolution might thereby provide an indicator of lifespan of species, terrestrial or not; (2) the likelihood that extraterrestrial life can be expected to be multicellular and social should be affected by ultraviolet and other mutagenic factors.

The Milwaukee Continuum: Older Veterans and Nonveterans Use Housing First to Exit Homelessness

2019 ◽  
pp. 002216781986652
Author(s):  
David A. Nelson ◽  
Jeff Morzinski ◽  
Mark Flower
Keyword(s):  
Healing Process ◽  
Community Based Participatory Research ◽  
Research Process ◽  
Public Health Issue ◽  
Community Based ◽  
Deep Time ◽  
Homeless Veterans ◽  
Process Understanding ◽  
Formerly Homeless

Background: Homelessness is about survival and more than an issue of bricks and mortar. It is not a static dimension and alludes to a troubled age and brokenness of society. Despite dramatic declines in numbers of people presently homeless, the issue continues to be a public health issue. The number of veterans currently homeless continues to be of national concern despite application of resources. More needs to be done to better understand the concerns of veterans, once homeless and now housed. Method: Qualitative research in the form of interviews provided insights from the veterans on their experience around achieving housing. Qualitative methods are often used in evaluations as they speak of the experience of the program being evaluated by capturing and then communicating the narratives of the participants. This study was grounded in community-based participatory research where a member of community was a part of all phases of the research process. Results: Seven interviews with formerly homeless veterans were conducted. Themes included the following: Burnt Brides and Regrets, Survival, Spirituality, Recovery and Stress, Supportive Care, Reunite Family, and Sickness and Health. Discussion: The themes provide insight into the experience of the veterans and a means to better understand the healing process. Understanding of the healing process includes the following: Acknowledging the Courage to go Deep, Time, Veterans Giving Back, and Recovery is Ongoing. Despite what was learned, further research is needed to better understand the long-term implications of people formerly homeless now housed.

Patterns in the evolution of nares size and secondary palate length in anomodont therapsids (Synapsida): implications for hypoxia as a cause of end-Permian tetrapod extinctions

2008 ◽  
Vol 82 (3) ◽  
pp. 528-542 ◽  
Author(s):  
Kenneth D. Angielczyk ◽  
Melony L. Walsh
Keyword(s):  
Atmospheric Oxygen ◽  
Term Trend ◽  
Weak Evidence ◽  
Secondary Palate ◽  
Respiratory Efficiency ◽  
Rigorous Study ◽  
Selection For ◽  
Long Term Trend ◽  
Do So

Seemingly consistent proportional differences in several palatal structures have been noted between Permian and Triassic anomodont therapsids for nearly a century. These patterns have been cited as evidence in support of a decline in atmospheric oxygen concentrations that may have contributed to end-Permian terrestrial extinctions. However, it is not known whether the observed differences are significant, or whether they stem from continued directional selection. If they are not significant, or if their timing does not match that proposed for the oxygen decline, support for the hypoxia-based extinction scenario would be weakened. We tested whether the internal nares and bony secondary palate, two palatal features proposed to be related to respiratory efficiency, are significantly larger in Triassic anomodonts, and whether the variation can be attributed to a long-term tendency for increase. Results based on raw data indicate that Triassic anomodonts have significantly larger secondary palates than Permian anomodonts. They also have significantly larger internal nares, but only when primitive, morphologically-divergent specimens are not considered. Although nares and palate size are correlated with stratigraphic occurrence, available data reject the hypothesis that the observed differences were the result of a long-term trend. Most of these findings are consistent with the predictions of the hypoxia scenario. However, removing the effects of body size and phylogeny causes some of the differences to break down, indicating that if selection for increased respiratory efficiency affected these characters, it was most likely not the only factor to do so. Therefore, the characters provide only weak evidence in support of the hypoxia scenario, and we recommend against their use for this purpose. Our results emphasize the need for caution when invoking presumed differences between Permian and Triassic vertebrates as support for hypoxia, or other extinction scenarios, without a rigorous study of the character(s) in question.

Healing Experiences of British Columbia First Nations Women: Moving Beyond Suicidal Ideation and Intention

1997 ◽  
Vol 16 (2) ◽  
pp. 69-89 ◽  
Author(s):  
D. L. Paproski
Keyword(s):  
British Columbia ◽  
Suicidal Ideation ◽  
First Nations ◽  
Role Models ◽  
Suicide Attempts ◽  
Process Analysis ◽  
Healing Process ◽  
Native Spirituality ◽  
The Impact ◽  
First Nations Women

This study explores how five British Columbia First Nations women moved through suicidal ideation and intention in their youth. Much of their healing process was facilitated by a reconnection to their cultural identity and traditional native spirituality. Phenomenological research methods were used to guide the interview process, analysis, and the interpretation of unstructured interviews. Each transcribed interview was analyzed for themes and developed into a narrative. Several procedures were used to examine the validity of the analysis and interpretation, including participant review of the findings. Three of the 12 themes that emerged suggest common experiences surrounding suicide attempts or ideation. These experiences suggest that the impact of separation from family, community, and culture was significant for each of these women. Nine of the 12 major themes describe a variety of healing experiences for these five women, involving elders or other role models, professional counsellors, family, and community. As a consequence of their healing experiences, all participants reported an increased sense of personal empowerment, a positive view of themselves, and a commitment to a positive future for themselves and other First Nations people. The significance of cultural connections and native spirituality may have important implications for the intervention and prevention of suicide in First Nations youth.

scholarly journals Pressure ulcers: Current understanding and newer modalities of treatment

2015 ◽  
Vol 48 (01) ◽  
pp. 004-016 ◽  
Author(s):  
Surajit Bhattacharya ◽  
R. K. Mishra
Keyword(s):  
Pressure Ulcers ◽  
Treatment Options ◽  
Healing Process ◽  
Treatment Algorithm ◽  
Wound Debridement ◽  
Advantages And Disadvantages ◽  
Prone Area ◽  
Long Time

ABSTRACTThis article reviews the mechanism, symptoms, causes, severity, diagnosis, prevention and present recommendations for surgical as well as non-surgical management of pressure ulcers. Particular focus has been placed on the current understandings and the newer modalities for the treatment of pressure ulcers. The paper also covers the role of nutrition and pressure-release devices such as cushions and mattresses as a part of the treatment algorithm for preventing and quick healing process of these wounds. Pressure ulcers develop primarily from pressure and shear; are progressive in nature and most frequently found in bedridden, chair bound or immobile people. They often develop in people who have been hospitalised for a long time generally for a different problem and increase the overall time as well as cost of hospitalisation that have detrimental effects on patient’s quality of life. Loss of sensation compounds the problem manifold, and failure of reactive hyperaemia cycle of the pressure prone area remains the most important aetiopathology. Pressure ulcers are largely preventable in nature, and their management depends on their severity. The available literature about severity of pressure ulcers, their classification and medical care protocols have been described in this paper. The present treatment options include various approaches of cleaning the wound, debridement, optimised dressings, role of antibiotics and reconstructive surgery. The newer treatment options such as negative pressure wound therapy, hyperbaric oxygen therapy, cell therapy have been discussed, and the advantages and disadvantages of current and newer methods have also been described.

Neighborhood Property–Based Pattern Selection for Support Vector Machines

2007 ◽  
Vol 19 (3) ◽  
pp. 816-855 ◽  
Author(s):  
Hyunjung Shin ◽  
Sungzoon Cho
Keyword(s):  
Learning Community ◽  
Large Data ◽  
Support Vector ◽  
Pattern Selection ◽  
Data Set ◽  
Vector Machines ◽  
Large Memory ◽  
Long Time ◽  
Practical Performance ◽  
Selection For

The support vector machine (SVM) has been spotlighted in the machine learning community because of its theoretical soundness and practical performance. When applied to a large data set, however, it requires a large memory and a long time for training. To cope with the practical difficulty, we propose a pattern selection algorithm based on neighborhood properties. The idea is to select only the patterns that are likely to be located near the decision boundary. Those patterns are expected to be more informative than the randomly selected patterns. The experimental results provide promising evidence that it is possible to successfully employ the proposed algorithm ahead of SVM training.

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