Depression and Anxiety in Pregnancy during COVID-19: A Rapid Review and Meta-Analysis

2021 ◽  
Author(s):  
Lianne Tomfohr-Madsen ◽  
Gerald Giesbrecht ◽  
Catherine Lebel ◽  
Nicole Racine ◽  
Sheri Madigan
Keyword(s):  
Pregnant Women ◽  
Meta Analysis ◽  
Systematic Search ◽  
Rapid Review ◽  
Depression And Anxiety ◽  
Inclusion Criteria ◽  
Pooled Prevalence ◽  
Prevalence Of Depression ◽  
Meta Analyses ◽  
In Pregnancy

Objective: The present study rapidly reviewed and meta-analyzed the worldwide prevalence of depression and anxiety among pregnant women during the COVID-19 pandemic. Methods: A systematic search of the literature and meta-analyses were conducted. Results: Fifteen studies with 11,091 participants met inclusion criteria. Depression was assessed in 11 studies, with a pooled prevalence of .265 or 26.5% and anxiety in 12 studies, with a pooled prevalence of .335 or 33.5%. Conclusions: Rates of depression and anxiety during pregnancy are elevated during the pandemic. There is an urgent need to ensure screening and treatment for depression and anxiety during pregnancy.

scholarly journals Depression and anxiety in pregnancy during COVID-19: A rapid review and meta-analysis

2021 ◽  
Vol 300 ◽  
pp. 113912 ◽  
Author(s):  
Lianne M. Tomfohr-Madsen ◽  
Nicole Racine ◽  
Gerald F Giesbrecht ◽  
Catherine Lebel ◽  
Sheri Madigan
Keyword(s):  
Meta Analysis ◽  
Rapid Review ◽  
Depression And Anxiety ◽  
In Pregnancy

scholarly journals Psychological distress among healthcare providers during COVID-19 in Asia: Systematic review and meta-analysis

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0257983
Author(s):  
Siew Mooi Ching ◽  
Kar Yean Ng ◽  
Kai Wei Lee ◽  
Anne Yee ◽  
Poh Ying Lim ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Healthcare Providers ◽  
Random Effects Model ◽  
Depression And Anxiety ◽  
Cross Sectional ◽  
Funnel Plot ◽  
Health And Wellbeing ◽  
Pooled Prevalence ◽  
Increased Risk ◽  
Prevalence Of Depression

Introduction COVID-19 pandemic is having a devastating effect on the mental health and wellbeing of healthcare providers (HCPs) globally. This review is aimed at determining the prevalence of depression, anxiety, stress, fear, burnout and resilience and its associated factors among HCPs in Asia during the COVID-19 pandemic. Material and methods We performed literature search using 4 databases from Medline, Cinahl, PubMed and Scopus from inception up to March 15, 2021 and selected relevant cross-sectional studies. Publication bias was assessed using funnel plot. Random effects model was used to estimate the pooled prevalence while risk factors were reported in odds ratio (OR) with 95% CI. Results We included 148 studies with 159,194 HCPs and the pooled prevalence for depression was 37.5% (95%CI: 33.8–41.3), anxiety 39.7(95%CI: 34.3–45.1), stress 36.4% (95%CI: 23.2–49.7), fear 71.3% (95%CI: 54.6–88.0), burnout 68.3% (95%CI: 54.0–82.5), and low resilience was 16.1% (95%CI: 12.8–19.4), respectively. The heterogeneity was high (I2>99.4%). Meta-analysis reported that both females (OR = 1.48; 95% CI = 1.30–1.68) and nurses (OR = 1.21; 95%CI = 1.02–1.45) were at increased risk of having depression and anxiety [(Female: OR = 1.66; 95% CI = 1.49–1.85), (Nurse: OR = 1.36; 95%CI = 1.16–1.58)]. Females were at increased risk of getting stress (OR = 1.59; 95%CI = 1.28–1.97). Conclusion In conclusion, one third of HCPs suffered from depression, anxiety and stress and more than two third of HCPs suffered from fear and burnout during the COVID-19 pandemic in Asia.

scholarly journals Comparative clinical trials in psychotherapy: Have large effects been replicated?

2020 ◽  
Vol 29 ◽  
Author(s):  
Nickolas D. Frost ◽  
Thomas W. Baskin ◽  
Bruce E. Wampold
Keyword(s):  
Clinical Trials ◽  
Treatment Efficacy ◽  
Literature Search ◽  
Meta Analysis ◽  
Effect Sizes ◽  
Depression And Anxiety ◽  
Inclusion Criteria ◽  
Average Quality ◽  
Meta Analyses

Abstract Aims The purpose of this review is to examine the replication attempts of psychotherapy clinical trials for depression and anxiety. We focus specifically on replications of trials that exhibit large differences between psychotherapies. The replicability of these trials is especially important for meta-analysis, where the inclusion of false-positive trials can lead to erroneous conclusions about treatment efficacy. Methods Standard replication criteria were developed to distinguish direct from conceptual replication methodologies. Next, an exhaustive literature search was conducted for published meta-analyses of psychotherapy comparisons. Trials that exhibited large effects (d > 0.8) were culled from these meta-analyses. For each trial, a cited replication was conducted to determine if the trial had been subsequently replicated by either ‘direct’ or ‘conceptual’ methods. Finally, a broader search was conducted to examine the extent of replication efforts in the psychotherapy literature overall. Results In the meta-analytic search, a total of N = 10 meta-analyses met the inclusion criteria. From these meta-analyses, N = 12 distinct trials exhibited large effect sizes. The meta-analyses containing more than two large effect trials reported evidence for treatment superiority. A cited replication search yielded no direct replication attempts (N = 0) for the trials with large effects, and N = 4 conceptual replication attempts of average or above average quality. However, of these four attempts, only two partially corroborated the results from their original trial. Conclusion Meta-analytic reviews are influenced by trials with large effects, and it is not uncommon for these reviews to contain several such trials. Since we find no evidence that trials with such large effects are directly replicable, treatment superiority conclusions from these reviews are highly questionable. To enhance the quality of clinical science, the development of authoritative replication criteria for clinical trials is needed. Moreover, quality benchmarks should be considered before trials are included in a meta-analysis, or replications are attempted.

Meta-Analyses of Predictors of Health Practices in Pregnant Women

2016 ◽  
Vol 40 (3) ◽  
pp. 425-446 ◽  
Author(s):  
Barbara L. Cannella ◽  
Adela Yarcheski ◽  
Noreen E. Mahon
Keyword(s):  
Pregnant Women ◽  
Meta Analysis ◽  
Health Practices ◽  
Inclusion Criteria ◽  
Maternal Fetal Attachment ◽  
Support Employment ◽  
The Mean ◽  
Fetal Attachment ◽  
Meta Analyses ◽  
Doctoral Dissertations

The aims of this study were to identify predictors of health practices of pregnant women in the literature reviewed, to use meta-analysis to ascertain the mean effect size (ES) across studies between each predictor and health practices, and to examine four moderators on each predictor–health practices relationship. Using preferred reporting items for systematic reviews and meta-analyses guidelines for the literature assessed, 32 published studies or doctoral dissertations completed between 1992 and 2015 met the inclusion criteria. Twelve predictors were identified, and each predictor in relation to health practices was subjected to meta-analysis. One predictor (maternal–fetal attachment) of health practices had a large ES, two predictors (depression and stress) had medium ESs, six predictors (income, education, parity, social support, employment, and age) had small ESs, and three predictors (gestational age, marital status, and race) had trivial ESs. Findings are interpreted relative to health practices in pregnant women.

Prevalence of depression, anxiety and stress in china during COVID-19 pandemic: A systematic review with meta-analysis

2020 ◽  
pp. 009121742097800
Author(s):  
Syeda Beenish Bareeqa ◽  
Syed Ijlal Ahmed ◽  
Syeda Sana Samar ◽  
Waqas Yasin ◽  
Sani Zehra ◽  
...  
Keyword(s):  
Mental Health ◽  
Meta Analysis ◽  
Early Period ◽  
Depression And Anxiety ◽  
Health Issues ◽  
Eligibility Criteria ◽  
Pooled Prevalence ◽  
Care Workers ◽  
Prevalence Of Depression ◽  
Novel Coronavirus

Background The novel coronavirus disease which is believed to have initially originated in Wuhan city of China at the end of 2019 was declared as pandemic by March 2020 by WHO. This pandemic significantly impacted the mental health of communities around the globe. This project draws data from available research to quantify COVID-19 mental health issues and its prevalence in China during the early period of the COVID-19 crisis. It is believed that this pooling of data will give fair estimate of the effects of the COVID-19 pandemic on mental health. Methods We conducted this study in accordance with PRISMA guidelines 2009. The protocol for this review is registered and published in PROSPERO (CRD42020182893). The databases used were Pubmed, Medline, Google scholar and Scopus. The studies were extracted according to pre-defined eligibility criteria and risk of bias assessment was conducted. The Meta-analysis was done using OpenMeta [analyst]. Results Total of 62382 participants in nineteen studies fulfilled the eligibility criteria. Stress was the most prevalent (48.1%) mental health consequence of Covid-19 pandemic, followed by depression (26.9%) and anxiety (21.8%). After performing subgroup analysis, prevalence of depression and anxiety in both females and frontline health care workers were high as compared to the prevalence in general Chinese population. Conclusion The prevalence of depression and anxiety is moderately high whereas pooled prevalence of stress was found to be very high in Chinese people during this Covid-19 crisis.

A Meta-Analysis on the Effectiveness of Prenatal Yoga in Reducing Cortisol Hormone in Pregnancy

2020 ◽  
Author(s):  
Shiva Aflahiyah ◽  
◽  
Didik Gunawan Tamtomo ◽  
Hanung Prasetya ◽  
◽  
...  
Keyword(s):  
Pregnant Women ◽  
Cortisol Level ◽  
Controlled Trial ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Well Being ◽  
The Body ◽  
Inclusion Criteria ◽  
In Pregnancy

ABSTRACT Backgrund: A growing body of evidence suggests that activity of the stress-responsive hypothalamic-pituitary-adrenal axis and its end-product cortisol also may be associated with perinatal emotional well-being. A number of preventive interventions, such as Yoga, targeting psychosocial and physiological risk factors for perinatal depression have utilized mind-body practices, which embody the idea that the mind interacts with the body to influence physical functioning, improve symptoms, and promote health. This study aimed to investigate effectiveness of prenatal yoga in reducing cortisol hormone in pregnancy Subjects and Method: This was a meta-analysis and systematic review. This study collected published articles during 2000 to 2020 from PubMed, Science Direct, Springer, Proquest, and Chocrane electronic databases. The inclusion criteria were full text, randomized controlled trial, and prenatal yoga intervention. The study subjects were pregnant women who received prenatal yoga for 8 to 20 weeks. Outcome was cortisol hormone reduction during pregnancy. The selected articles were analyzed by PRISMA flow chart and RevMan 5.3. Results: 5 articles from America and Asia were met the inclusion criteria. This study had high heterogeneity (I2=88%; p<0.001). Therefore, this study used random effect model (REM). Prenatal yoga reduced cortisol level 0.59 times in pregnancy (Mean Difference= -0.59; 95% CI= 1.18 to 0.01; p= 0.050). Conclusion: Prenatal yoga is effective to reduce cortisol level in pregnant women. Keywords: prenatal yoga, cortisol hormone, pregnant women Correspondence: Shiva Aflahiyah. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36 A, Surakarta 57126, Central Java. Email: [email protected]. DOI: https://doi.org/10.26911/the7thicph.05.47

The Effects of Ferric Carboxymaltose Versus Iron Sucrose on the Ferritin Level in Pregnant Women with Anemia: A Meta-Analysis

2020 ◽  
Author(s):  
Astika Candra Nirwana ◽  
◽  
Yulia Lanti Retno Dewi ◽  
Bhisma Murti ◽  
◽  
...  
Keyword(s):  
Pregnant Women ◽  
Ferritin Level ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Iron Sucrose ◽  
Ferric Carboxymaltose ◽  
Inclusion Criteria ◽  
Anemia In Pregnancy ◽  
In Pregnancy

ABSTRACT Background: Prophylactic oral iron is recommended during pregnancy to meet the increased requirement during the antenatal period. The most commonly used iron preparation for anemia in pregnancy is iron sucrose complex (ISC). The purpose of this study was to compare the effects of ferric carboxymaltose versus iron sucrose on the ferritin level in pregnant women with anemia. Subjects and Method: This was a meta-analysis study. The study was conducted by collecting published articles from 2010 to 2019 in PubMed, Science Direct, and Google Scholar databases. The keywords used to search the articles including “Ferric Carboxymaltose”, “Ferric Carboxymaltose and anemia in pregnancy”, and “the effect of Ferric Carboxymaltose for anemia”. The inclusion criteria was full text with randomized control trial study, anemia therapy provision using ferric carboxymaltose versus iron sucrose, and the study subjects were pregnant women with anemia. The selected articles were analyzed using Revman 5.3. Results: 5 articles that meet the inclusion criteria were selected for this study. There was high heterogeneity between experiment group (I2 = 96%; p= 0.020). Therefore, this study used random effect model. Ferric carboxymaltose provision increased feritin level 0.89 times than iron sucrose (Mean Difference= 0.89; 95% CI= 0.12 to 1.66; p<0.001). Conclusion: Ferric carboxymaltose is effective to increased feritin level in pregnant women. Keywords: ferric carboxymaltose, iron sucrose, randomized controlled trial Correspondence: Astika Candra Nirwana. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 085640018896 DOI: https://doi.org/10.26911/the7thicph.05.48

scholarly journals Global trend of Plasmodium malariae and Plasmodium ovale spp. malaria infections in the last two decades (2000–2020): a systematic review and meta-analysis

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Joseph Hawadak ◽  
Rodrigue Roman Dongang Nana ◽  
Vineeta Singh
Keyword(s):  
Pregnant Women ◽  
Assessment Tool ◽  
Meta Analysis ◽  
Plasmodium Malariae ◽  
Malaria Prevalence ◽  
Plasmodium Ovale ◽  
African Region ◽  
Asymptomatic Patients ◽  
Pooled Prevalence ◽  
Meta Analyses

Abstract Background Recent studies indicate that the prevalence of non-falciparum malaria, including Plasmodium malariae and Plasmodium ovale spp., is increasing, with some complications in infected individuals. The aim of this review is to provide a better understanding of the malaria prevalence and disease burden due to P. malariae and P. ovale spp. Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and the Joanna Briggs Institute prevalence study assessment tool were used to select and evaluate the studies, respectively. Six databases: PubMed, WHOLIS, Wiley Library, ScienceDirect, Web of Science and Google Scholar were used to screen articles published during the period January 2000–December 2020. The pooled prevalence estimates for P. malariae and P. ovale spp. were analysed using a random-effects model and the possible sources of heterogeneity were evaluated through subgroup analysis and meta-regression. Results Out of the 3297 studies screened, only 113 studies were included; among which 51.33% were from the African Region. The P. malariae and P. ovale spp. pooled prevalence were 2.01% (95% CI 1.31–2.85%) and 0.77% (95% CI 0.50–1.10%) respectively, with the highest prevalence in the African Region. P. malariae was equally distributed among adults (2.13%), children (2.90%) and pregnant women (2.77%) (p = 0.862), whereas P. ovale spp. was more prevalent in pregnant women (2.90%) than in children ≤ 15 years (0.97%) and in patients > 15 years old (0.39%) (p = 0.021). In this review, data analysis revealed that P. malariae and P. ovale spp. have decreased in the last 20 years, but not significantly, and these species were more commonly present with other Plasmodium species as co-infections. No difference in prevalence between symptomatic and asymptomatic patients was observed for either P. malariae or P. ovale spp. Conclusion Our analysis suggests that knowledge of the worldwide burden of P. malariae and P. ovale spp. is very important for malaria elimination programmes and a particular focus towards improved tools for monitoring transmission for these non-falciparum species should be stressed upon to deal with increased infections in the future. Graphic Abstract

scholarly journals Prevalence of Methicillin-Resistant Staphylococcus Aureus (MRSA) infection in patients with Cystic Fibrosis: a meta-analysis

2019 ◽  
Author(s):  
Sagad Omer Obeid Mohamed ◽  
Almigdad H. M. Ali ◽  
Abazr A. H. Ibrahim ◽  
Mahmoud Elnil ◽  
Almutasim B. E. Elhassan ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Meta Analysis ◽  
Healthcare Providers ◽  
Inclusion Criteria ◽  
Methicillin Resistant ◽  
Pooled Prevalence ◽  
Mrsa Infection ◽  
Meta Analyses

Abstract Background Methicillin-resistant staphylococcus aureus (MRSA) infection is increasingly being reported among patients with cystic fibrosis (CF) and contributes to pulmonary morbidity in CF, with poorer prognosis. The aim of this study was to assess the prevalence of MRSA infection in patients with CF. Methods We conducted this study according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Databases of MEDLINE/PubMed, WHO-Virtual Health Library (VHL), ScienceDirect, Google Scholar and OpenGrey were searched to recruit the relevant articles. Pooled prevalence with the corresponding 95% confidence interval (CI) was calculated using OpenMeta Analyst software, and heterogeneity among studies was estimated using the I2 statistics. Results According to our inclusion criteria, 27 studies included a total of 47,413 patients were analyzed. The pooled prevalence of MRSA in patients with CF was 15.2% (95% CI 9.70%– 20.7%). Subgroup analyses and meta-regression showed that the prevalence of MRSA in patients with CF was significantly associated with different geographical areas (P<0.001), data collection method (P<0.001), sample obtaining source (P<0.001), and study year (P = 0.006). Conclusions prevalence of MRSA infection is increasing in patients with CF. the results of this study could provide a reference for further controlling transmission and the management of patients with CF. Healthcare providers need to be aware of the clinically important association between MRSA infection and CF to ensure effective management.

scholarly journals Low vegetable intake in pregnancy and associated maternal factors: A scoping review

2021 ◽  
Author(s):  
Kira Simmons ◽  
Nina Meloncelli ◽  
Lauren Kearney ◽  
Judith Maher
Keyword(s):  
Pregnant Women ◽  
Scoping Review ◽  
Vegetable Intake ◽  
Economic Status ◽  
Positive Association ◽  
Inclusion Criteria ◽  
Scoping Reviews ◽  
Meta Analyses ◽  
The Relationship ◽  
In Pregnancy

Healthy eating is identified as a priority in pregnancy. Vegetables are low energy, nutrient dense foods that support health. Needs of populations differ by demographics, as such there is a need to investigate vegetable intake (VI) in pregnant women of lower socio-economic status (SES). The aim of this scoping review is 1) To describe VI during pregnancy in serves/gram and compare VI to recommendations; and 2) To explore the relationship between VI during pregnancy and maternal SES characteristics. Using Arksey and O’Malley’s framework and the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR), studies were identified in a search of electronic databases (MEDLINE, Web of Science, Global Health and Scopus) published up to July 2021. All observational studies assessing VI in pregnancy, written in English and conducted in an energy replete context worldwide, were included for review. Forty-seven publications met inclusion criteria. While VI of pregnant women varies across populations, VI falls below recommendations worldwide. Studies investigating older age (n=9), higher education (n=7), higher income (n=4) and VI, consistently found a positive association, whereas a negative association with food insecurity (n=4) was identified. Other variables explored that may influence VI is limited and too fragmented to generalise. Inconsistencies and possible inaccuracies in reporting VI may be related to the considerable variation in tools used for assessing VI. In conclusion, low VI in pregnancy needs to be addressed, with a particular focus on women of lower SES due to greater vulnerability to low VI.

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