scholarly journals Pharmacognostic, phytochemical, physicochemical and TLC profile study Mace (Aril) of Myristica malabarica Lamk. (Myristicaceae)

2017 ◽  
Vol 6 (6) ◽  
pp. 329-334
Author(s):  
Seema Yuvraj Mendhekar ◽  
◽  
Chetana Dilip Balsaraf ◽  
Mayuri Sharad Bangar ◽  
SL Jadhav ◽  
...  
Keyword(s):  
Quality Control ◽  
Chemical Constituents ◽  
Western Ghat ◽  
Medicinal Uses ◽  
Crude Drug ◽  
Phytochemical Investigation ◽  
Anti Oxidant ◽  
Sedative Hypnotics ◽  
Profile Study

The plant Myristica malabarica Lamk. is traditionally used as a medicine and spices in food . It is belonging to family Myristicaceae. The plant is native to India and endangered trees are mostly found in western ghat. Extracted with various solvents by successive soxhlet hot extraction processs with increasing order of polarity on phytochemical investigation. The extract has shown alkaloids, saponin, tannin and flavones glycosides. It has important medicinal uses like Ayurvedic Medicines. It is traditionally used as anticancer, antiInflammatory, anti-Oxidant, Sedative hypnotics, Antimicrobial, Antifertility, Hepatoprotective and cytotoxicity. The chemical constituents such as Malabaricones, Malabaricanol, Isoflavones are isolated .Myristica Fragrans also known as fragnant Nutmeg or true Nutmeg. The present study i.e. Pharmacognostic, Phytochemical, Physicochemical and TLC Profile Study of Mace (Aril) Of Myristica malabarica Lamk. is helpful in the characterization of the crude drug. Physiochemical and phyto-chemical analysis of mace confirm the quality and purity of plant and its identification. The information collected is useful for further pharmacological and therapeutical evaluation of mace (Aril) Of Myristica malabarica Lamk. and anthology of quality control of crude drug.

A review on phyto-pharmacology of Oxalis corniculata

2021 ◽  
Vol 24 ◽  
Author(s):  
Iqra Sarfraz ◽  
Azhar Rasul ◽  
Ghulam Hussain ◽  
Muhammad Ajmal Shah ◽  
Bushra Nageen ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Current Effort ◽  
Isolation And Characterization ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Fungal ◽  
Warm Temperate

: Oxalis corniculata (Oxalidaceae) is a small decumbent and delicate appearing medicinal herb flourishing in warm temperate and tropical domains such as Pakistan and India. Main bioactive chemical constituents of Oxalis plant include several alkaloids, flavonoids, terpenoids, cardiac glycosides, saponins, phlobatannins along with steroids. Due to its polyphenolic, glycosides and flavonoid profile, it is proved to be protective in numerous ailments and exhibit various biological activities such as anti-fungal, anti-cancer, anti-oxidant, anti-bacterial, anti-diabetic, and cardioprotective. Moreover, bioactive phytochemicals from this plant possess significant wound healing potential. Our current effort intends to emphasize on the immense significance of this plant species, which have not been the subject matter of clinical trials and effective pharmacological studies, even though its favored usage has been stated. This review proposes that Oxalis corniculata possess potential for the cure of various diseases, however, further researches on isolation and characterization of bioactive compounds along with pre-clinical trials are compulsory to figure out its pharmacological applications.

scholarly journals Characterization of UV-Sensitive Marker Constituents of Polygala Root for TLC: Applications in Quality Control of Single Crude Drug Extract Preparations

2018 ◽  
Vol 66 (12) ◽  
pp. 1174-1180 ◽  
Author(s):  
Takashi Uchikura ◽  
Hidemi Sugiwaki ◽  
Morio Yoshimura ◽  
Hiromi Mitsuhashi ◽  
Hiroyuki Fuchino ◽  
...  
Keyword(s):  
Quality Control ◽  
Crude Drug ◽  
Sensitive Marker

scholarly journals 4-Hydroxy-trans-cinnamate Derivatives and Triterpene from Barleria cristata

2014 ◽  
Vol 12 (2) ◽  
pp. 143-145 ◽  
Author(s):  
Nipa Chowdhury ◽  
Abdullah Al Hasan ◽  
Fakir Shahidullah Tareq ◽  
Monira Ahsan ◽  
ATM Zafrul Azam
Keyword(s):  
Medicinal Plant ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Spectroscopic Methods ◽  
Isolation And Characterization ◽  
Phytochemical Investigation ◽  
Organic Extracts ◽  
Whole Plants ◽  
Important Medicinal Plant

Barleria cristata is an important medicinal plant of Bangladesh. Many compounds of diverse biological activities were isolated from different Barleria species, including irridoids, flavonoids and phenylethanoid derivatives in addition to other groups of chemical constituents. This paper presents the chemical investigation of the whole plants of B.cristata. Classic phytochemical investigation of organic extracts of the whole plants of B. cristata together with spectroscopic methods led to the isolation and characterization of 4-hydroxy-trans-cinnamate derivatives (1-3) and a triterpene, namely oleanolic acid (4). Dhaka Univ. J. Pharm. Sci. 12(2): 143-145, 2013 (December) DOI: http://dx.doi.org/10.3329/dujps.v12i2.17623

scholarly journals A REVIEW ON PHARMACOLOGICAL ACTIVITIES OF POLYALTHIA LONGIFOLIA L

2021 ◽  
pp. 172-177
Author(s):  
Dhiren k Vaghela ◽  
Dhruv Pandya ◽  
Hitesh Solanki
Keyword(s):  
Antimalarial Activity ◽  
Chemical Constituents ◽  
Antiulcer Activity ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Plant Parts ◽  
Ornamental Tree ◽  
Anti Oxidant ◽  
Polyalthia Longifolia

Polyalthia longifolia L. is an ornamental tree (mostly used as an avenue tree) which belongs to Annonaceae. As per the review of the research papers it also has so many important chemical constituents in its different parts. These chemicals are alkaloids, flavonoids, phenols, terpenoids and essensial oil etc that can be used for the preparation of different medicines for several diseases. In this review authors focused on the pharmacological properties and ethnomedicinal properties of the plant parts and their implementation in the pharmacological science. The plant part different extracts showed different types of pharmacological activities like Antibacterial activity, Antifungal activity, Antitumor (Anticancer activity), cytotoxic activity, Anti-oxidant activity, Anti-inflammatary activity, Antimalarial activity and Antiulcer activity. Even the plant also has so many traditional medicinal uses. So, its not just an ornamental tree but it can be good resourse for the secondary metabolites and considered as medicinally important plant.

scholarly journals Pharmacological aspects & medicinal uses of Trigonella foenum-graecum: A Current Review

2021 ◽  
Vol 12 (4) ◽  
pp. 776-786
Author(s):  
Veer Inder Singh ◽  
Rahul Kumar Sharma ◽  
Yogesh Kumar ◽  
Sadique Saqulain
Keyword(s):  
Chemical Constituents ◽  
Health Impact ◽  
Daily Basis ◽  
High Morbidity ◽  
Pharmaceutical Drugs ◽  
Long Term Conditions ◽  
Medicinal Uses ◽  
Trigonella Foenum Graecum ◽  
Serious Infections ◽  
Anti Oxidant

Globally a large number of people are affected by acute and chronic diseases resulting in high morbidity and mortality rate. A huge amount of pharmaceutical drugs are being manufactured on a daily basis to combat these diseases. But due to their high cost and deleterious effects, it becomes critically important to state emphasis on finding an alternative way to manage these long term conditions. Medicinal herbs could provide a good source of dietary supplement combined with existing therapies. Many scientific studies have demonstrated that medicinal plants and herbs have the potential for the treatment of many serious infections and many disorders. Out of these herbs, Fenugreek is recognized as an oldest herb with great medicinal potential. Fenugreek harbors many essential macronutrients and micronutrients along with trace elements. Numerous chemical constituents present in fenugreek highlights a variety of pharmacological activity such as anti-glycemic activity, anti-oxidant capacity, anti-inflammatory effects, hypocholesterolemic activity and many more. This article explores the diverse active compounds and potential pharmacological applications of Trigonella foenum-graecum also known as fenugreek. It also focuses on the medicinal significance and health impact of taking fenugreek in our day to day nutrition.

scholarly journals ISOLATION AND CHARACTERIZATION OF β-SITOSTEROL FROM ELAEAGNUS ANGUSTIFOLIA CULTIVATED IN IRAQ

2018 ◽  
Vol 11 (11) ◽  
pp. 442 ◽  
Author(s):  
Rand A Zeez ◽  
Ibrahim S Abaas ◽  
Enas J Kadhim
Keyword(s):  
Chemical Constituents ◽  
Elaeagnus Angustifolia ◽  
Crystalline Powder ◽  
Isolation And Purification ◽  
Spectral Identification ◽  
Isolation And Characterization ◽  
Phytochemical Investigation ◽  
1H Nuclear Magnetic Resonance ◽  
Layer Chromatography

Objective: The aim of our study was to investigate chemical constituents of leaves and seeds of Elaeagnus angustifolia since no phytochemical investigation had been done previously in Iraq.Methods: Phytochemical screening of the extracts obtained from the leaves of E. angustifolia indicated the presence of flavonoids (type of flavonols), saponins, alkaloids, steroids, and terpenoids. Thin-layer chromatography fingerprinting and the spraying reagent (concentrated H2SO4 and vanillin in ethanol) were used to identify the hexane extract containing phytosterols.Results: The different chromatographic and spectroscopic results revealed the presence of β‐sitosterol isolated from E. angustifolia. Conclusion: The isolation and purification afforded white crystalline powder which was subjected to chemical and spectral identification by infrared and 1H-nuclear magnetic resonance. The compound was identified as β‐sitosterol.

scholarly journals Phytochemical Investigation and Characterization of Isolated Chemical Constituents from Kyllinga triceps Rottb.

2017 ◽  
Vol 29 (6) ◽  
pp. 1393-1400
Author(s):  
Nishant Verma ◽  
K.K. Jha ◽  
Shamim Ahmad ◽  
Sudhir Chaudhary ◽  
Mohammad Ali
Keyword(s):  
Chemical Constituents ◽  
Phytochemical Investigation

scholarly journals Isolation and Characterization of an Amide, (2S)2-Hydroxy-N-((3R,4R)-1,3,4-Trihydroxytridecan-2-YL)Undecamide, from the Root Bark of Ficus exasperata (Vahl)

2020 ◽  
pp. 1-6
Author(s):  
O. E. Famobuwa ◽  
E. A. Adekunbi ◽  
H. O. Oloyede ◽  
A. Oyebade
Keyword(s):  
Ethyl Acetate ◽  
Silica Gel ◽  
Amorphous Powder ◽  
Root Bark ◽  
Medicinal Uses ◽  
Mass Spectral ◽  
Compound C ◽  
Isolation And Characterization ◽  
Anti Oxidant

Silica gel (70-230 mesh ASTM) was packed into a column (45 cm × 3 cm) using the dry method. About 7 g of extract was mixed with 30 g of silica gel and allowed to dry. It was then loaded onto the column and successively eluted initially with pet ether 100%, followed by 10%, 20%, 40%, 60%, 80% chloroform in pet-ether; followed by 100% chloroform; 20%, 50% ethyl acetate in chloroform; followed by 100% ethyl acetate and then 20% and 50% methanol in ethyl acetate. 25 fractions were collected in 50 ml aliquots and bulked together according to their TLC profiles and Rf.                                                                                                               The bulked fraction was further column chromatographed over silica gel (70-230 mesh) using a pipette and isocratically eluting with pet-ether: chloroform: methanol 67:25:8. 30 fractions of 2 ml each were collected. Compound C-3 (200 mg) was obtained from the fractions 1-15 as an off-white amorphous powder. The combination of IR, 1HNMR, 13CNMR, gCOSY, HMBC, HSQC and Mass spectral data on this off-white powder has led to an unambiguous assignment and the compound, an amide, isolated from the bioactive fraction of F. exasperata has the chemical name (2S)2-hydroxy-N-((3R,4R)-1,3,4-trihydroxytridecan-2-yl)undecamide. The acclaimed medicinal uses of this plant such as antihypertensive, anti-inflammatory, anti-arthritic, anti-ulcerogenic, anti-microbial and anti-oxidant, among others made it attractive to the authors.

In-vivo evaluation of lipid lowering ability of Chloris paraguaiensis extracts

2020 ◽  
Vol 7 (2) ◽  
pp. 21-24
Author(s):  
Pavani C H
Keyword(s):  
Medicinal Plants ◽  
Chemical Constituents ◽  
The Body ◽  
Lipid Lowering ◽  
Medical Systems ◽  
In Vivo Evaluation ◽  
Standard Drug ◽  
Anti Oxidant ◽  
And Control

Hyperlipidemia is the immediate results of the excessive fat intake in food. This results in the elevated levels of cholesterol and triglycerides in the blood. This leads to heart conditions like CAD, hypertension, congestive heart failure as risk factors which can be lethal. There are many drugs to treat and control the lipids levels in the body. These drugs are either designed to prevent LDL accumulation and VLDL synthesis. Some drugs also lower the elevated levels of saturated lipids in the body. But many drugs are known to cause side effects and adverse effects; therefore, alternatives to the drugs are the subjects for current investigations. Herbs and medicinal plants are used as treatment sources for many years. They have been used in the Indian medical systems like Ayurveda, Siddha etc. As the application of herbs in the treatment is growing, there is an urgent need for the establishment of Pharmacological reasoning and standardization of the activity of the medicinal plants. Chloris paraguaiensis Steud. is Poyaceae member that is called locally as Uppugaddi. Traditionally it is used to treat Rheumatism, Diabetes, fever and diarrhoea. The chemical constituents are known to have anti-oxidant properties and most of the anti-oxidants have anti-hyperlipidemic activity too. Since the plant has abundant flavonoid and phenol content, the current research focusses on the investigation of the anti-hyperlipidemic activity of the plant Chloris extracts. Extracts of Chloris at 200mg/kg showed a comparably similar anti hyperlipidemia activity to that of the standard drug. The extracts showed a dose based increase in the activity at 100 and 200mg/kg body weight.

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