scholarly journals A REVIEW ON PHARMACOLOGICAL ACTIVITIES OF POLYALTHIA LONGIFOLIA L

2021 ◽  
pp. 172-177
Author(s):  
Dhiren k Vaghela ◽  
Dhruv Pandya ◽  
Hitesh Solanki
Keyword(s):  
Antimalarial Activity ◽  
Chemical Constituents ◽  
Antiulcer Activity ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Plant Parts ◽  
Ornamental Tree ◽  
Anti Oxidant ◽  
Polyalthia Longifolia

Polyalthia longifolia L. is an ornamental tree (mostly used as an avenue tree) which belongs to Annonaceae. As per the review of the research papers it also has so many important chemical constituents in its different parts. These chemicals are alkaloids, flavonoids, phenols, terpenoids and essensial oil etc that can be used for the preparation of different medicines for several diseases. In this review authors focused on the pharmacological properties and ethnomedicinal properties of the plant parts and their implementation in the pharmacological science. The plant part different extracts showed different types of pharmacological activities like Antibacterial activity, Antifungal activity, Antitumor (Anticancer activity), cytotoxic activity, Anti-oxidant activity, Anti-inflammatary activity, Antimalarial activity and Antiulcer activity. Even the plant also has so many traditional medicinal uses. So, its not just an ornamental tree but it can be good resourse for the secondary metabolites and considered as medicinally important plant.

Phytochemical, Pharmacological Activities and Ayurvedic Significances of Magical Plant Mimosa pudica Linn

2020 ◽  
Vol 17 ◽  
Author(s):  
Vijay Kumar
Keyword(s):  
Therapeutic Potential ◽  
Wide Spectrum ◽  
Chemical Constituents ◽  
Future Research ◽  
Mimosa Pudica ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
Crude Extracts ◽  
Anti Cancer

: Mimosa pudica Linn is an integrated part of Traditional Medicines Systems of India, China, Africa, Korea and America. It has been used from centuries in traditional medicines to cure different diseases like fever, diabetes, constipation, jaundice, ulcers, biliousness, and dyspepsia. It is an important ingredient of wide class of herbal formulations. To assess the scientific evidence for therapeutic potential of Mimosa pudica Linn and to identify the gaps for future research. The available information on the ethno-medicinal uses, phytochemistry, pharmacology and toxicology of Mimosa pudica Linn was collected via a library and electronic searches in Sci-Finder, Pub-Med, Science Direct, Google Scholar for the period, 1990 to 2020. In traditional medicinal systems, variety of ethno-medicinal applications of Mimosa pudica Linn has been noticed. Phytochemical investigation has resulted in identification of 40 well known chemical constituents, among which alkaloids, phenols and flavionoids are the predominant groups. The crude extracts and isolates have exhibited a wide spectrum of in vitro and in vivo pharmacological activities including anti-cancer, anti-inflammation, osteoporosis, neurological disorders, hypertension etc.. To quantify the Mimosa pudica Linn and its formulations, analytical techniques like HPLC and HPTLC has shown dominancy with good range of recovery and detection limit. Mimosa pudica Linn is the well-known herb since an ancient time. The pharmacological results supported some of the applications of Mimosa pudica Linn in traditional medicine systems. Perhaps, the predominance of alkaloids, phenols and flavionoids are responsible for the pharmacological activities the crude extracts and isolates of Mimosa pudica Linn. Further, there is need to isolate and evaluate the active chemical constituents of Mimosa pudica Linn having significant medicinal values. In future, it is important to study the exact mechanism associated with the phytochemicals of Mimosa pudica Linn especially on anti-cancer activities. Notably, toxicity studies on Mimosa pudica Linn are limited which are to be explored in future for the safe application of Mimosa pudica Linn and its formulations.

Phytochemical and Pharmacological Review on Two Herbs of Baijiangcao: Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss

2020 ◽  
Vol 17 (5) ◽  
pp. 496-517
Author(s):  
Yangcheng Liu ◽  
Wei Liu ◽  
Jiaqi Wang ◽  
Yang Liu ◽  
Changlan Chen ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Volatile Components ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Scientific Databases ◽  
The Past ◽  
Current State ◽  
Patrinia Scabiosaefolia ◽  
Antiviral Activities

Patrinia scabiosaefolia Fisch. Trev. and Patrinia villosa (Thunb.) Juss, are two species of Patrinia recorded in the Chinese Pharmacopoeia with the same Chinese name “Baijiangcao” and similar therapeutic effect in traditional Chinese medicine. The present article is the first comprehensive review on the chemical composition and pharmacological activities of these herbs. In this review, data on chemical constituents and pharmacological profile of the two herbs are provided. This review discusses all the classes of the 223 compounds (phenylpropanoids, flavonoids, terpenes, saponins and volatile components, etc.) detected in the two herbs providing information on the current state of knowledge of the phytochemicals present in them. In the past three years, our research group has isolated and identified about more than 100 ingredients from the two herbs. Therefore, we published a systematic review of our research papers and studies on the two herbs were carried out using resources such as classic books about Chinese herbal medicine and scientific databases including Pubmed, Web of Science, SciFinder, CNKI. etc. The present review discusses the most thoroughly studied pharmacological activities (antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, antitumor and antiviral activities) of the two herbs. This comprehensive review will be informative for scientists searching for new properties of these herbs and will be important and significant for the discovery of bioactive compounds from the two herbs and in complete utilization of Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss.

A Review of Phytochemical and Pharmacological Studies of Inula Species

2020 ◽  
Vol 16 (5) ◽  
pp. 557-567
Author(s):  
Aparoop Das ◽  
Anshul Shakya ◽  
Surajit Kumar Ghosh ◽  
Udaya P. Singh ◽  
Hans R. Bhat
Keyword(s):  
Bacterial Infections ◽  
Chemical Constituents ◽  
Valuable Insight ◽  
Important Ingredient ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
The Family ◽  
Pharmacological Studies ◽  
Perennial Herbs ◽  
Insight Into

Background: Plants of the genus Inula are perennial herbs of the family Asteraceae. This genus includes more than 100 species, widely distributed throughout Europe, Africa and Asia including India. Many of them are indicated in traditional medicine, e.g., in Ayurveda. This review explores chemical constituents, medicinal uses and pharmacological actions of Inula species. Methods: Major databases and research and review articles retrieved through Scopus, Web of Science, and Medline were consulted to obtain information on the pharmacological activities of the genus Inula published from 1994 to 2017. Results: Inula species are used either alone or as an important ingredient of various formulations to cure dysfunctions of the cardiovascular system, respiratory system, urinary system, central nervous system and digestive system, and for the treatment of asthma, diabetes, cancers, skin disorders, hepatic disease, fungal and bacterial infections. A range of phytochemicals including alkaloids, essential and volatile oils, flavonoids, terpenes, and lactones has been isolated from herbs of the genus Inula, which might possibly explain traditional uses of these plants. Conclusion: The present review is focused on chemical constituents, medicinal uses and pharmacological actions of Inula species and provides valuable insight into its medicinal potential.

scholarly journals TERMINALIA CHEBULA: SUCCESS FROM BOTANY TO ALLOPATHIC AND AYURVEDIC PHARMACY

2016 ◽  
Vol 9 (5) ◽  
pp. 21
Author(s):  
Varun Garg ◽  
Barinder Kaur ◽  
Sachin Kumar Singh ◽  
Bimlesh Kumar
Keyword(s):  
Chemical Constituents ◽  
Present Review ◽  
Terminalia Chebula ◽  
Pharmacological Activities ◽  
Therapeutic Uses ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Inflammatory

ABSTRACTTerminalia chebula (TC) is a unique herb having various therapeutic potentials as anti-inflammatory, antioxidant, anticancer, and digestant. It belongsto family Combretaceae. In the present review, an attempt has been made to decipher classification, chemical constituents, therapeutic uses, andpatents that have been reported for TC. Various pharmacological activities of TC that make it as potential medicine and its Ayurvedic formulationsare highlighted.Keywords: Terminalia chebula, Anti-oxidant, Anti-cancer, Ayurvedic formulations, Anti-oxidant.

Phytochemical and pharmacological aspects of Nothapodytes nimmoniana. An overview

2013 ◽  
Vol 59 (1) ◽  
pp. 53-66 ◽  
Author(s):  
Nazeerullah Khan ◽  
Ennus Tajuddin Tamboli ◽  
V.K. Sharma ◽  
Sunil Kumar
Keyword(s):  
Wide Spectrum ◽  
Pharmacological Activities ◽  
Nothapodytes Nimmoniana ◽  
Jammu And Kashmir ◽  
Medicinal Uses ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Fungal ◽  
Anti Hiv ◽  
Important Medicinal Plant

Summary Nothapodytes nimmoniana (J. Graham) (Icacinaceae), commonly known as Amruta is found in India particularly in Maharashtra, Goa, Kerala, Assam, Jammu and Kashmir as well as Tamilnadu areas. It is an important medicinal plant, the major source of a potent alkaloid, namely camptothecin, of a wide spectrum of pharmacological activities like anti-cancer, anti-HIV, antimalarial, antibacterial, anti-oxidant, anti-inflammatory, anti-fungal and also applied in the treatment of anaemia. Camptothecin is still not synthesized, therefore, its production entirely depends on natural sources. N. nimmoniana is one such plant which yields contain camptothecin in significantly high amount. The plant is gaining international recognition due to its diversified medicinal uses. It is subjected to excessive harvest. It has been categorized as a vulnerable and endangered plant. The present review encompasses the phytochemical, analytical, pharmacological, biotechnological, and other specific aspects of N. nimmoniana.

scholarly journals Morphology, Phytochemistry and Pharmacological Activity of Vitex negundo: An Overview

2020 ◽  
Vol 10 (3-s) ◽  
pp. 280-285
Author(s):  
Yogendra Singh ◽  
Pankaj Mishra ◽  
Pushpendra Kannojia
Keyword(s):  
Chemical Constituents ◽  
Iridoid Glycosides ◽  
Plant Morphology ◽  
Antitubercular Activity ◽  
Depth Information ◽  
World Population ◽  
Vitex Negundo ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Traditional Medicines

Now days a herbal and traditional medicines mostly used in all over the world according to WHO, about 60 to 65% world population practicing herbal and traditional medicines. Vitex negundo Linn. is an aromatic herb belong to family Verbenaceae. It is also known as Nirgundi, Five leaved chaste tree. Plants have many chemical constituents as flavonoids, volatile oil, triterpenes, diterpenes, sesquiterpenes, lignan, flavones, glycosides, iridoid glycosides and stilbene derivative. These chemical constituents are present in each part of the plant. Vitex negundo extract have various pharmacological activities such as anti-inflammatory, antipyretic, anti-arthritic, antioxidant, analgesic activity, antibacterial activity, antitumor activity, anti-amnesic activity, anxiolytic activity, Nephroprotective activity, anti-HIV activity, Antitubercular activity, antieosinophilic activity, anti-snake venom activity. This review article provides depth information related to plant morphology, cultivation, chemical constitutes, pharmacological activities and their medicinal uses. Keywords: Vitex negundo, Nirgundi, Casticin, Anti-Gout Activity

Phytochemistry and Pharmacological Activities of the Genus Swertia (Gentianaceae): A Review

2017 ◽  
Vol 45 (04) ◽  
pp. 667-736 ◽  
Author(s):  
Jie Li ◽  
Yan-Li Zhao ◽  
Heng-Yu Huang ◽  
Yuan-Zhong Wang
Keyword(s):  
Secondary Metabolites ◽  
Biosynthetic Pathway ◽  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Reverse Transcriptases ◽  
Cns Depressant ◽  
Anti Oxidant ◽  
Broad Variety ◽  
Multiple Ligands ◽  
Swertia Species

Swertia plants have been considered to be medicinal plants useful for the treatment of various ailments for thousands of years, especially in Asian countries. This is due to the broad variety of chemical compounds that provide multiple ligands for bonding to different endogenous biomacromolecules for patients. Chemical constituents and pharmacological activities of Swertia plants are summarized in this paper. Approximately 419 metabolites and 40 bioactive compounds have been reported from 30 Swertia species, including xanthones, flavonoids, seco-iridiods, iridiods, triterpenoids, alkaloids, volatiles, and other secondary metabolites. The bioactivities of Swertia plants include anticarcinogenic, hepatoprotective, anti-oxidant, hypoglycemic, anthelmintic, antibacterial, antifungal, anti-diabetic, gut, and airways modulatory, metabolizing isozymes inhibitory, neuroprotective, HIV-I reverse transcriptases inhibitory, anticholinergic, and CNS-depressant activities, etc. In addition, biosynthetic pathways of xanthones, and seco-iridiods, two most important secondary metabolites for Swertia, are elucidated. The xanthones biosynthetic pathway is a mixed biosynthetic pathway involved the shikimate and the malonate routes, and the seco-iridoid pathway starts with geraniol derived from IPP which is produced either via the MEP or the MVA pathway. This review will offer a reference for future researches on the protection of natural resources, the investigation of therapeutic basis, new drug development, and so forth. Metabolic pathways of some crucial active compounds were also discussed in this review.

scholarly journals Ethnomedicinal Uses, Phytochemistry and Pharmacological Activities of Pittosporum floribundum Wight. & Arn. – A Review

2020 ◽  
pp. 48-55
Author(s):  
Kishangiri Kirtigiri Gunsai ◽  
Abhay Jayprakash Gandhi ◽  
Rabinarayan Acharya ◽  
V. J. Shukla
Keyword(s):  
Methanolic Extract ◽  
Stem Bark ◽  
Extensive Literature ◽  
Phytochemical Screening ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Anti Oxidant ◽  
Ethnobotanical Uses ◽  
Ethnomedicinal Uses ◽  
Different Parts

Objectives: Pittosporum floribundum Wight & Arn. (Pittosporaceae) has been associated with many therapeutic claims, especially for its ethnomedicinal and economical uses. In this review, an extensive literature survey was carried out to compile information available about its medicinal uses, phytochemistry and pharmacological properties. Materials and Methods: Ethnobotanical uses of P. floribundum reported in available books on ethnobotany and ethnomedicinal research articles have been compiled. The obtained data are arranged in a tabular form, enlisting its local names, their area of presence and parts used. Therapeutic indications, external or internal dosage form and usage of the drug are also noted. Results and Discussion: It was found that stem bark, leaves, and root of P. floribundum are used to combat itching, rheumatism, leprosy, sprain, eczema, arthritis, diabetes, chest pain and antidote for snake bite. Bark has maximum applications in leprosy, and sprain. The extracts of the different parts were subjected to phytochemical screening for the presence of phytoconstituents such as alkaloids, flavonoids, phenols, lignins, anthroquinones, steroids, tannins, saponins, fixed oils and glycosides. Studies have shown that the methanolic extract of bark having promising antifungal, antibacterial, anti-inflammatory, antioxidant, hepatoprotective, neuropharmacological and behaviour activities. Conclusion: P. floribundum has multifaceted uses in varied aspects thus underlining its significance. Reported claimed anti-bacterial and anti-oxidant activities can be further strengthened through pharmacological and clinical studies to establish the ethnic claims like leprosy, sprain, bruises, sciatica, pulmonary affection and phthisis.

scholarly journals Cocculus hirsutus (L.) W.Theob. (Menispermaceae): A Review on Traditional Uses, Phytochemistry and Pharmacological Activities

Medicines ◽  
2020 ◽  
Vol 7 (11) ◽  
pp. 69
Author(s):  
Rajan Logesh ◽  
Niranjan Das ◽  
Anjana Adhikari-Devkota ◽  
Hari Prasad Devkota
Keyword(s):  
Skin Diseases ◽  
Chemical Constituents ◽  
Scientific Information ◽  
Bibliographic Databases ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Traditional Uses

Background:Cocculus hirsutus (L.) W.Theob. (Menispermaceae) is a perennial climber distributed mostly in tropical and subtropical areas. The main aim of this article is to collect and analyze the scientific information related to traditional uses, bioactive chemical constituents and pharmacological activities. Methods: Scientific information on C. hirsutus was retrieved from the online bibliographic databases (e.g. MEDLINE/PubMed, SciFinder, Web of Science, Google Scholar and Scopus). Information regarding traditional uses was also acquired from secondary resources including books and proceedings. Results: Different plant parts of C. hirsutus were reported to be used for the treatment of fever, skin diseases, stomach disorders and urinary diseases. Alkaloids such as jasminitine, hirsutine, cohirsitine and their derivatives along with a few flavonoids, triterpene derivatives and volatile compounds were reported from whole plant or different plant parts. Extracts were evaluated for their antimicrobial, antidiabetic, immunomodulatory and hepatoprotective activities among others. Conclusion: Although widely used in traditional medicines, only a few studies have been performed related to chemical constituents. Most of the biological activity evaluations were carried out using in vitro evaluation methods and only a few studies were carried out in animal models. In the future, properly designed in vivo and clinical studies are necessary to evaluate the pharmacological activities of C. hirsutus along with bioassay-guided studies to isolate and identify the active constituents.

scholarly journals A Review on Ethnopharmacological Applications and Pharmacological Activities of Leea macrophylla

2021 ◽  
pp. 58-61
Keyword(s):  
Medicinal Plants ◽  
Modern Medicine ◽  
In Vivo Studies ◽  
Pharmacological Activities ◽  
Plant Parts ◽  
Synthetic Drugs ◽  
Research Activities ◽  
Anti Oxidant

Plants are used as a potential source of medicines since the prehistoric period. Medicinal plants are the richest bio-resource of drugs of a number of traditional systems of medicines. Medicinal plants can also be used as nutraceuticals, food supplements, folk medicines, pharmaceutical intermediates, and chemical entities for synthetic drugs. A good number of researches on medicinal plants have enriched the science of modern medicine over the last decades. Leea macrophylla (Leeaceae) locally known as ‘Hastikarna palasa’ is a shrub that has been used in herbal medicine as a cure for a number of disorders. Several studies have proven that the plant possesses potential antimicrobial, anti-oxidant, anti-inflammatory, analgesic, neuropharmacological and anti-diabetic activities. Tribal communities used the plant parts as a remedy for a number of ailments as well as nutritional products. Established in-vitro and in-vivo studies were conducted to get evidence of pharmacological activities of the plant parts. This review paper focuses on the phytopharmacological activities and traditional uses of the plant which may help further research activities on L. macrophylla by giving up-to-date information about the plant.

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