scholarly journals Areca catechu L. (Chikni Supari): A Review Based Upon its Ayurvedic and Pharmacological Properties

2021 ◽  
Vol 10 (5) ◽  
pp. 338-344
Author(s):  
Manish Grover ◽  

Areca catechu belongs to the family Palmae and is commonly known by different names such as chikni supari, areca nut and betel nut. The fruit of this plant is called the areca nut, which carries significant medicinal properties. This plant is also mentioned in various ancient Sanskrit scriptures. The plant is mainly used for chewing and religious purposes of the Hindus of India. India is the largest consumer and producer of areca nut globally, which produces about 52% of the world production. Medicinally, the plant is used to treat leucoderma, diarrhea, anaemia, obesity, leprosy etc. In Ayurveda, the plant is astringent, diuretic, digestion-promoting, stimulant, wound healing and laxative agent. The plant is associated with various therapeutic and pharmacological potentials, including wound healing, antidepressant, antihelmintic, antihypertensive, antioxidant, antiallergic, antifungal and antimicrobial properties. However, this plant is considered as carcinogenic as it can cause mouth cancer. In this review article, attempts have been made to summarize the phytochemistry, folk uses and ayurvedic uses along with its pharmacological activities

Author(s):  
Kamla Moond ◽  
Hitesh Vyas ◽  
Harisha C. R. ◽  
V. J. Shukla

Objective: The Areca catechu L. is a tropical fruit, which is also called betel nut and is widely distributed in different parts of the world. Areca catechu L is used for various treatment aliments in the form of various preparations especially in powdered form and it used extensively in Ayurveda to treat Mukhavikara, Aruchi, Yonishaithilya, Shvetapradara etc. Areca nut is commonly used as betel nut or supari, as it is often chewed wrapped in betel leaves (Paan). The aim is to assessment of Mahabhautika dominance in Pugaphala by pharmacognostical and pharmaceutical study.Methods: Microscopic, macroscopic study and phsico-chemical analysis of Pugaphala Churna.Results: In present study Pugaphala was selected as a Parthiva dominant drug according to its Rasa Panchaka, after that its Mahabhautika dominancy was assessed by pharmacognostical and pharmaceutical study and results also support that in Pharmaceutical study loss on drying is 4.4%w/w, in Pharmacognostical study Rhomboidal crystal, Lignified scleroid etc. were found these characters also showed that Pugaphala is having dominancy of Prithvi Mahabhuta.Conclusion: Prithvi dominancy in Pugaphala is scientifically assessed by Pharmacognostical and Pharmaceutical study.


2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Alba Cortés Alfaro

Introduction adolescents represent a vulnerable group exposed to sexually transmitted infections including HIV/AIDS. It is a stage in which they are subjected to constant changes in physical, mental and social development and risk factors such as ignorance, early sex, drug addiction, social inequality, gender and myths contribute to this exposure. Objective: To delve into the characteristics of adolescents that put them at risk of acquiring an STI-HIV/AIDS. Methods: A bibliographic review was carried out where the databases included in the LILACS, EBSCO and HINARI services were consulted, and very good coverage was achieved, both in Cuba, Latin America and the Caribbean, and in the rest of the world. Conclusions: This review article on the risks to which adolescents are subjected to acquiring an STI-HIV/AIDS is put in the hands of all personnel involved in working with adolescents. For the family doctor in particular for being a staff closely linked to the community, allowing them to be in better conditions to detect these behaviors thus contributing to exercise and undertake prevention actions that will allow us to achieve the objectives of our Ministry of Public Health in relation to with this indicator.


Author(s):  
ARCHANA TIWARI ◽  
AVINASH TIWARI

Plants are not only the source of food, oxygen, and shelter, but the same are also a potential foundation of medicines. Many natural and plant-derived antimicrobial and wound healing compounds have been recognized. In the present review, we have studied the main bioactive components of Acacia catechu with their medicinal roles. Most of these bioactive components are secondary metabolites which are produced by plants as side products of certain physiological reactions and are of no use for the plant itself. These components have been reported for their medicinal properties. In this review, we have mentioned some antibacterial, antifungal, and wound healing properties of A. catechu with its known bioactive components. The aim of this review article is, to enlist the possible potent bioactive components of the plant, against pathogenic microbes that can replace the use of chemicals and synthetic antibiotics for the treatment of skin infections and other diseases.


2022 ◽  
Vol 18 ◽  
Author(s):  
Sanjay Kumar ◽  
Shiv Gupta ◽  
Varsha Rani ◽  
Priyanka Sharma

Background: Pyrazole scaffolds have gained importance in drug discovery and development for various pharmacological activities like antiviral, antifungal, anticancer, antidepressant, anti-inflammatory, antibacterial, etc. Additionally, the pyrazole moiety has shown potent anti-HIV activity as a core heterocycle or substituted heterocycles derivatives (mono, di, tri, tetra, and fused pyrazole derivatives). To assist the development of further potential anti-HIV agents containing pyrazole nucleus, here we have summarized pyrazole containing anti-HIV compounds that have been reported by researchers all over the world for the last two decades. Objective: The present review concentrates on an assortment of pyrazole containing compounds, particularly for potential therapeutic activity against HIV. Methods: Google Scholar, Pubmed, and SciFinder were searched databases with ‘‘pyrazol’’ keywords. Further, the year of publication and keywords ‘‘Anti-HIV’’ filter was applied to obtain relevant reported literature for anti-HIV agents containing pyrazole as a core or substituted derivatives. Results: This review article has shown the comprehensive compilation of 220 compounds containing pyrazole nucleus and possessing anti-HIV activity by sorting approximately 40 research articles from 2001 to date. 1-(4-Benzoylpiperazin-1-yl)-2-(4-fluoro-7-(1H-pyrazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (13), 3-(3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-fluoro-1H-pyrrolo[2,3-c]pyridin-7-yl)-1H-pyrazole-5-carboxamide (31), 3-(3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-fluoro-1H-pyrrolo[2,3-c]pyridin-7-yl)-1H-pyrazole-5-carboxamide (88), 3-cyanophenoxypyrazole derivative (130), and 4-(4-chlorophenyl)-5-(4-methyl-5-((4-nitrophenyl)diazenyl)thiazol-2-yl)-3-phenyl-5,6-dihydro-4H-pyrazolo[4,3-d]isoxazole (178) were the most potent mono-, di-, tri-, tetra-substituted, and fused pyrazole derivatives, respectively, which have shown potent anti-HIV activity among all the described derivatives as compared with standard anti-HIV drugs. Conclusion: This review article provides an overview of the potential therapeutic activity of pyrazole derivatives against HIV that will be helpful for designing pyrazole containing compounds for anti-HIV activity.


Author(s):  
Afroz Patan

 Objective: The main objective of review is an effort to give detailed information on Valeriana jatamansi and its multiple medicinal properties. Methods: As per the literature, the plant V. jatamansi is a perennial herb and found at subtemperate Himalayan regions of the Kumaon and Garhwal. The plant most popularly known as “Valerian.” The plant belongs to the family Valerianaceae. The roots and rhizomes of the plants are traditionally used to treat ulcers, jaundice, dry cough, seminal weakness, skin diseases, leprosy, and for sleep enhancement due to the presence of a variety of different chemical constituents such as sesquiterpenes, coumarins, iridoids, lignanoids, alkaloids, and flavonoids. From literature, the reported methods performed for different pharmacological activities have been thoroughly discussed and complied. Results: Most of the studies compiled from literature shown that V. jatamansi possess antimicrobial, antioxidant, anti-inflammatory, cytotoxic, anxiolytic, and neuroprotective activities. Conclusion: The review reveals that continuous research on this plant is needed to know the exact molecular mechanism and further elaborative studies can lead to develop safe therapeutic use in modern medicine.


2020 ◽  
pp. 1-3
Author(s):  
Tirna Purkait ◽  
Nandini Dutta

Moringa oleifera, popularly known as Drumstick, is a highly valued plant grown in the tropics and subtropics and one of the vegetables of the Brassica order and belongs to the family Moringaceae. It shows impressive medicinal properties and have great nutritional value. The leaves are rich in vitamins, minerals and have other essential phytochemicals which shows positive physiological benifits. Moringa plant provides a rich and rare combination of zeatin, quercetin, kaempferol and many other phytochemicals. Extracts from the leaves are used to treat malnutrition. It contains antioxidant and shows anticancer, anti-inflammatory, antidiabetic and antimicrobial properties. Scientific studies have given insight about usage of Moringa oleifera as a fortifying agent in foods as a cure of diabetes and cancer. Researches on efficacy of various processing techniques like drying, dehydration, blanching etc. are done to check the efficacy of the process and to check the loss of nutrients during processing.


2012 ◽  
Vol 3 (1) ◽  
pp. 162-166 ◽  
Author(s):  
L. I. Faly

Complex assessment of possibilities of infected wound healing with a help of screwworms of blowfly of the family Calliphoridae in the hospitals of Ukraineis offered. On the basis of available data the mechanism of therapeutic action is shown, and the medicinal properties of substances containing in the secretions and excretions of the blowfly screwworms are described. The gist of the treatment method and traits of the blowfly cultivation in a laboratory are highlighted. The quality standards for specialized biological laboratories are presented. The proposed wound healing method is proved as promising.


2019 ◽  
Vol 7 (1) ◽  
pp. 19-25
Author(s):  
Ave Olivia Rahman ◽  
Humaryanto Humaryanto

ABSTRACT Background: Some plants, such as betel nuts (Areca catechu), is used as traditional antiseptic. Betel nut mash is applied on ulcus wound.  Fibroblast and collagen are important factor in wound healing.  Research objective : this study is to determine the effect of betel nuts extract on fibroblast and collagen level in full thickness wound healing processs. Methodology: this study used male rats Sprague dawney that randomly divided into 3 groups. Groups I received no treatment, groups II and III received areca catechu extracts with concentration 15% and 30%  respectively. There are 12 rats in each groups. The treatment is given every day without wound’s debridement. Incision were made full thickness with diameter size 1,5 cm, on right back skin was made by lidocain anesthesia subcutaneously. Wound area were measured every days. Termination of rats were done in day 7 and day 16 to histopathology assessment with Haematoxylin-Eosin stain for fibroblast and collagen level by semiqualitative score. Results: level of collagen were higher in group that received extract but level of fibroblast were lower than control group in histopathology of day 7th. Conclusion:  Extract of betel nut increased level of collagen. Keyword : areca catechu, betel nuts, wound, fibroblast, collagen, histopathology   ABSTRAK Latar belakang :  Beberapa tanaman digunakan sebagai antiseptik luka, salah satunya biji pinang  untuk penyembuhan luka ulkus. Fibroblast dan kolagen merupakan salah satu faktor penting dalam penyembuhan luka. Tujuan : Penelitian ini bertujuan mengetahui efek ekstrak biji pinang terhadap level fibroblast dan kolagen pada proses penyembuhan luka full thickness  Metode : Penelitian ini menggunakan tikus galur Sprague dawney jantan berusia 2-3 bulan dan telah mendapatkan persetujuan etik. Setelah aklimatisasi, tikus dibagi secara acak masing-masing 12 ekor dalam 3 kelompok, yaitu kelompok I tanpa perlakuan, kelompok II diberikan salep ekstrak biji pinang 15%, kelompok III diberikan salep ekstrak biji pinang 30%. Luka full thickness dibuat dengan diameter 1,5 cm di daerah punggung belakang bagian kanan dengan anestesi lidokain subkutan. Perlakuan dilakukan setiap hari tanpa debridemen luka. Luas luka diukur  setiap hari. Terminasi dilakukan pada hari ke 7 dan 16 untuk pemeriksaan histopatologi jaringan luka dengan pengecatan Haematoxylin-Eosin. Skoring secara semikualitatif untuk menilai fibroblast dan kolagen. Hasil : Pada kelompok ekstrak pinang terdapat peningkatan level kolagen, akan tetapi tidak terjadi peningkatan level fibroblast pada hasil histopatologi luka kulit hari ke-7.  Kesimpulan :  terjadi peningkatan level kolagen pada pemberian ekstrak biji pinang. Kata kunci : biji pinang, luka, histopatologi, fibroblast, kolagen


2021 ◽  
Author(s):  
Aanchal Bansal ◽  
Chinmayee Priyadarsini

Phytochemicals are produced by plants as a defence mechanism against pathogens. They are used to treat various metabolic, immunological and neurological disorders in humans in various parts of the world as a part of traditional medicine. The use of indigenous plants in commercial medicine is rising with increasing population. The antimicrobial properties of plant extracts led to increased demands. Plant tissue culture on the other hand, has proved to be a reliable alternative for the production of bioactive compounds from plants. Artificial plant culture can enhance the production of phytochemicals in medicinal plants. This review focuses on the medicinal properties of phytochemicals and their in-vitro production.


Author(s):  
Vidhi Makwana ◽  
Abhaykumar Kethwas ◽  
Niravkumar Sapoliya ◽  
Krupa Limbachiya ◽  
Sanjay Gamit ◽  
...  

Aim: Typha genus belongs to the family Typhaceae and is comprising of about 13 known species distributed in the subtropical and tropical regions of North America, South America, Asia, Africa, Australia and Europe. Several species are considered as invasive weeds that colonize wetlands and marshes because they are highly productive by clonal growth, forming very large, persistent and often monospecific stands. This review offers detailed information on the aquatic species of the cosmopolitan genus Typha L. with specific focus on their distribution, identification, importance in bioremediation, usability and traditional uses along with chemical and biological diversity. Methodology: An extensive browsing in three electronic databases (Unbound Medline, PubMed and ScienceDirect) and internet search engines (Scifinder and Google Scholar) enabled us to connote the studies on Typha genus available till date. Results: Literature survey corroborated that some species of Typha are valuable as sources of traditional medicine in human health, while some are still widely used for non-pharmacological purposes. Numerous phytochemical investigations of plants of this genus confirmed the presence of alkaloids, glycosides, tannins, steroids, phenols, saponins, flavanoids, carbohydrates, proteins, oils and fats. Besides, various studies cited in this review article have demonstrated that the extracts or active substances that have been isolated from the species of Typha genus have multiple pharmacological activities. Conclusion: The review draws the attention of scientists towards the utility and important issues associated with the probable approaches that should be investigated to encourage people to take maximal benefit of the potentially useful species of Typha genus.


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