scholarly journals Перспективи використання методики лікування інфікованих ран за допомогою личинок падальних мух родини Calliphoridae

2012 ◽  
Vol 3 (1) ◽  
pp. 162-166 ◽  
Author(s):  
L. I. Faly
Keyword(s):  
Wound Healing ◽  
Quality Standards ◽  
Treatment Method ◽  
Therapeutic Action ◽  
Infected Wound ◽  
The Family ◽  
Medicinal Properties

Complex assessment of possibilities of infected wound healing with a help of screwworms of blowfly of the family Calliphoridae in the hospitals of Ukraineis offered. On the basis of available data the mechanism of therapeutic action is shown, and the medicinal properties of substances containing in the secretions and excretions of the blowfly screwworms are described. The gist of the treatment method and traits of the blowfly cultivation in a laboratory are highlighted. The quality standards for specialized biological laboratories are presented. The proposed wound healing method is proved as promising.

scholarly journals The Study of the Wound Healing Activity of the Gel with a Comprehensive Therapeutic Effect

2019 ◽  
Vol 7 (6) ◽  
pp. 908-912
Author(s):  
Liliana Lyubanovna Brkich ◽  
Andrey Anatolievich Nedorubov ◽  
Natalia Valeryevna Pyatigorskaya ◽  
Galina Eduardovna Brkich ◽  
Elena Sergeevna Odintsova
Keyword(s):  
Wound Healing ◽  
Therapeutic Effect ◽  
Specific Activity ◽  
Therapeutic Action ◽  
Infected Wound ◽  
Reference Drug ◽  
Acrylic Polymers ◽  
Infected Wounds ◽  
Derivatives Of ◽  
Wound Healing Activity

AIM: The study was aimed at researching the specific wound healing activity of the drug with a comprehensive therapeutic effect based on derivatives of glucosamine and acrylic polymers to treat the infected wounds of various origins on a model of a planar infected wound. METHODS: The model of septic wounds in rats as per the method of P.I. Tolstykh was used during the study of the specific activity of the drug with a comprehensive therapeutic effect based on derivatives of glucosamine and acrylic polymers for the treatment of infected wounds. The infection was performed with the S. aureus and E. coli strains. The study lasted 18 days, and during this period no full scarring occurred. The wound diameter was chosen as the effectiveness criterion. The planimetric method was used to assess the course of the wound process in experimental animals. RESULTS: The obtained data prove the specific action of the drug with a comprehensive therapeutic action based on derivatives of glucosamine and acrylic polymers to treat the infected wounds of various origins. The study has shown that bacterially infected wounds healed worse than noninfected ones. Both types of wounds — infected and uninfected ones — healed faster when applying the test drug or Levomekol ointment. CONCLUSION: On the model of a planar infected wound, the developed drug with a comprehensive therapeutic action has shown better wound healing effect compared with the Levomekol reference drug.

scholarly journals Areca catechu L. (Chikni Supari): A Review Based Upon its Ayurvedic and Pharmacological Properties

2021 ◽  
Vol 10 (5) ◽  
pp. 338-344
Author(s):  
Manish Grover ◽  
Keyword(s):  
Wound Healing ◽  
Antimicrobial Properties ◽  
Review Article ◽  
Areca Nut ◽  
Betel Nut ◽  
Pharmacological Activities ◽  
The Family ◽  
Areca Catechu ◽  
The World ◽  
Medicinal Properties

Areca catechu belongs to the family Palmae and is commonly known by different names such as chikni supari, areca nut and betel nut. The fruit of this plant is called the areca nut, which carries significant medicinal properties. This plant is also mentioned in various ancient Sanskrit scriptures. The plant is mainly used for chewing and religious purposes of the Hindus of India. India is the largest consumer and producer of areca nut globally, which produces about 52% of the world production. Medicinally, the plant is used to treat leucoderma, diarrhea, anaemia, obesity, leprosy etc. In Ayurveda, the plant is astringent, diuretic, digestion-promoting, stimulant, wound healing and laxative agent. The plant is associated with various therapeutic and pharmacological potentials, including wound healing, antidepressant, antihelmintic, antihypertensive, antioxidant, antiallergic, antifungal and antimicrobial properties. However, this plant is considered as carcinogenic as it can cause mouth cancer. In this review article, attempts have been made to summarize the phytochemistry, folk uses and ayurvedic uses along with its pharmacological activities

scholarly journals Medicinal Functions of Physalis Fruits for Biomedical Applications

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Abdel-Fattah WI ◽  
◽  
El-Bassyouni GT ◽  
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Biologically Active ◽  
Primary And Secondary Metabolites ◽  
Physalis Peruviana ◽  
Medicinal Value ◽  
The Family ◽  
Medicinal Properties

Drug innovation using natural products is an interesting mission for planning new leads. It describes the bioactive compounds resulting from natural resources, characterization and pharmacological examination. It emphases on the triumph of these resources in the process of finding and realizing new and effective drug compounds that can be beneficial for human resources. For medicinal devotions and for the progress of pharmaceutical substances, medicinal plants were used such as Physalis angulata L which is a medicinal plant used for numerous therapies including wound healing [1]. Physalis peruviana (golden berry) is an herbaceous annual plants belongs to the family Solanaceae [2]. This plant has a tremendous medicinal value for curing out different diseases: cancer, leukemia, diabetes, ulcers, malaria, asthma, hepatitis, dermatitis, rheumatism and several other diseases [3]. The golden berry fruit tastes like a sweet tomato and includes high levels of vitamin C, vitamin A and the vitamin B-complex. The fruit was demonstrated to have both antiinflammatory and antioxidant properties [4,5]. Herbal specialists and local people of several countries have used many extracts of medicinal plants to achieve and treat various diseases comprising wound healing [6]. Physalis with its notable benefits related to high nutrients and bioactive compounds with extraordinary antioxidant activity and other several medicinal properties have been ascribed to these compounds [7,8]. The bioactive compounds are formed as primary and secondary metabolites of the fruits. These compounds are biologically active with cytotoxic, antimicrobial, antioxidant, antiviral, fungicidal, insecticidal, tranquilizing, analgesic, anti-inflammatory, and contraceptive actions, among others. Such compounds are used for several dedications, such as in medical therapy, to cure diseases, in the cosmetics, and in the food industry as antioxidants or flavorings [9] (Figure 1).

scholarly journals An Updated Review on Wrightia tinctoria (Roxb). R Br

2021 ◽  
pp. 234-244
Author(s):  
Sangeetha S ◽  
Akhil Hari ◽  
Sijo Pattam ◽  
P. Nihal ◽  
A. Athira
Keyword(s):  
Wound Healing ◽  
Chemical Constituents ◽  
Tropical Region ◽  
Anti Cancer ◽  
The Family ◽  
Scientific Approach ◽  
Ancient Times ◽  
Medicinal Properties ◽  
Anti Inflammatory ◽  
Wrightia Tinctoria

Since ancient times human utilized the nature to cure various ailments. The knowledge of medicinal plants resulted in the development of various indigenous systems of medicine worldwide. Serendipitous discovery as well as scientific approach on the reason for medicinal properties of plants gave the knowledge of chemical constituents such as secondary metabolites in plants. Wrightia tinctoria which is commonly known as ‘Danthapala’ is a known potential medicinal plant, the leaves of which is traditionally used in the treatment of psoriasis and non-specific dermatitis in Siddha and Ayurvedic systems of medicine and distributed in tropical region belongs to the family Apocynaceae. This plant is beneficial for the treatment of dandruff, various scalp and skin disorders. Phytochemical and pharmacological investigation on the various parts of the plant showed anti-ulcer, anti-inflammatory, analgesic, anthelmintic, anti-cancer, anti-dandruff, wound healing and anti-anxiety activity. The current review focus on providing an update on the recent pharmacological and phytochemical investigations on the plant by researchers around the globe with special emphasis on Antisporiatic, Antifungal, Antibacterial, Antiviral, Cytotoxic, Anti-inflammatory, Anti-diabetic, Analgesic, Hepatoprotective, Anthelmintic, and Wound healing activities.

Meiotic chromosome behavior of Haworthia limifolia

2016 ◽  
Vol 5 (03) ◽  
pp. 4902
Author(s):  
Afrin Nazli ◽  
Kamini Kumar*
Keyword(s):  
Genetic Recombination ◽  
Meiotic Chromosome ◽  
Pollen Sterility ◽  
Meiotic Abnormalities ◽  
Chromosome Behavior ◽  
The Family ◽  
Medicinal Properties ◽  
Fruit Formation ◽  
Meiosis I ◽  
Chromosomal Behaviour

Haworthia limifolia is a xerophytic plant belonging to the family Liliaceae and is indigenous to Africa. It is use extensively for its medicinal properties like antibacterial, antifungal properties and used for the treatment of sores, superficial burns, as a blood purifier and to promote pregnancy in women and cattles. In present investigation chromosomal behaviour of H. limifolia in meiosis was studied. In diplotene stage chiasmata was observed showing the possibilities of genetic recombination. Chromosome clumps were observed in diakinesis indicating sticky nature of chromosomes. Meiotic abnormalities like stickiness, precocious movement, formation of bridges and laggards were also reported in both meiosis I and II. A fairly high percentage of pollen sterility that is 73.41% was recorded resulting in failure of fruit formation. This plant could be designated as facultative apomict (Swanson, 1957) as the only means of reproduction found was asexual or vegetative.

scholarly journals Recent Advances in Fiber–Hydrogel Composites for Wound Healing and Drug Delivery Systems

Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 248
Author(s):  
Marta O. Teixeira ◽  
Joana C. Antunes ◽  
Helena P. Felgueiras
Keyword(s):  
Drug Delivery ◽  
Wound Healing ◽  
Mechanical Stability ◽  
Fiber Spinning ◽  
Comprehensive Overview ◽  
Triggered Drug Release ◽  
Medicinal Properties ◽  
Hydrogel Composites ◽  
Drug Incorporation ◽  
Stimuli Sensitive

In the last decades, much research has been done to fasten wound healing and target-direct drug delivery. Hydrogel-based scaffolds have been a recurrent solution in both cases, with some reaching already the market, even though their mechanical stability remains a challenge. To overcome this limitation, reinforcement of hydrogels with fibers has been explored. The structural resemblance of fiber–hydrogel composites to natural tissues has been a driving force for the optimization and exploration of these systems in biomedicine. Indeed, the combination of hydrogel-forming techniques and fiber spinning approaches has been crucial in the development of scaffolding systems with improved mechanical strength and medicinal properties. In this review, a comprehensive overview of the recently developed fiber–hydrogel composite strategies for wound healing and drug delivery is provided. The methodologies employed in fiber and hydrogel formation are also highlighted, together with the most compatible polymer combinations, as well as drug incorporation approaches creating stimuli-sensitive and triggered drug release towards an enhanced host response.

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