scholarly journals Histopathological spectrum of salivary gland lesions in rural India

2021 ◽  
Vol 11 (1) ◽  
pp. 1830-1836
Author(s):  
Deepu Mathew Cherian ◽  
Rahul M Jadhav ◽  
Shaikh Murtuza ◽  
Tooba Fatima ◽  
Kashinath S Bhople
Keyword(s):  
Salivary Gland ◽  
Rural Population ◽  
Wide Spectrum ◽  
Medical Science ◽  
Malignant Lesion ◽  
Female Ratio ◽  
Medical College ◽  
Female Predominance ◽  
Male Female Ratio ◽  
Malignant Lesions

Background: Salivary gland lesions are of a wide spectrum and affect all the major and minor salivary glands in varying proportions. This study, performed in a rural medical college in Maharashtra, India is intended to see the histopathologic spectrum of salivary gland lesions in the rural population and how it is related to the data from other parts of the country and of the world.  Materials and Methods: This is a retrospective study done in the Department of Pathology of a rural-based medical college, Indian Institute of Medical Science and Research, Warudi, Maharashtra, India for a period of 6 years, from January 2014 to January 2020. Age, sex, location of the lesion, gross and microscopic findings were noted.Results: A total of 71 lesions were received in the department of pathology during this period. Samples were received from age 11 years to 75 years. Female preponderance with a male: female ratio of 1:1.15 was seen. 57.7% (n=41) were benign, 15.5% (n=11) were malignant and the rest (n=19) were inflammatory in nature. A maximum number of lesions (50.7%) were detected in the Parotid gland. The most common lesion seen was Pleomorphic adenoma (36.62%, n=26) and the most common malignant lesion was Mucoepidermoid carcinoma.Conclusions: Present study showed benign and non-neoplastic lesions outnumbering the malignant lesions, with female predominance, and a low mean age for malignant lesions of 38.2years. Comparison with other studies within and outside India showed a similar pattern of distribution of salivary gland lesions in the rural population. 

scholarly journals Safety of 0.1% topical tacrolimus in the treatment of vitiligo

2014 ◽  
Vol 13 (3) ◽  
pp. 255-259
Author(s):  
Samaresh Chandra Hazra ◽  
Nafiza Ahmed ◽  
Jagodish Chandra Ghosh
Keyword(s):  
Adverse Effect ◽  
Response Rate ◽  
Medical Science ◽  
Newly Diagnosed ◽  
Female Ratio ◽  
Topical Tacrolimus ◽  
Medical College ◽  
Male Female Ratio ◽  
Different Response ◽  
Cure Rates

Cure rates for vitiligo are significantly lower because of problems to different studies have reported different response rate and different adverse effect for the treatment of vitiligo. This study was conducted to evaluate the response rate and adverse effect of topical tacrolimus 0.1% ointment in the treatment of vitiligo patients in the department of Dermatology and venereology, Bangladesh Medical college (BMC), Dhaka from January 2010 to July 2010. In this clinical trial, 30 newly diagnosed vitiligo (focal and segmental) patients, aged between 10 to 50 years were assigned for therapy and to observe the response and adverse effect. Each individual lesion was treated with topical tacrolimus 0.1% ointment twice daily for three months. All the patients completed three months treatment and available for statistical analysis. The highest percentage 13(43.3%) was in the age of 11-20 years. Sex ratio revealed higher in case of female 18(60%), with a male-female ratio 1:1.5 and 5(16.67%) patients had vitiligo among their families. Repigmentation was observed in 8 (26.7%) subjects at the end of 4th week, 15 (50.1%) subjects at 8th week and 25 (83.3%) subjects after 12 weeks of therapy. 25 (83.33%) subjects did not complain any adverse effect (like pruritus, burning etc.) and 5 (16.67%) subjects were suffered from different adverse effect of drug, like pruritus observed in 2 (6.7%) subjects and burning in 6 (20%) subjects. This study found that tacrolimus 0.1% ointment to be safe in the treatment of vitiligo, with reduction in the number of vitiliginous spots by increased repigmentation significantly. DOI: http://dx.doi.org/10.3329/bjms.v13i3.19147 Bangladesh Journal of Medical Science Vol.13(3) 2014 p.255-259

scholarly journals The clinical study and management of lateral neck masses

2017 ◽  
Vol 4 (3) ◽  
pp. 1071
Author(s):  
Amol Vasantrao Deshpande ◽  
Amit Narayan Pothare
Keyword(s):  
Radical Neck Dissection ◽  
Neck Mass ◽  
Lateral Neck ◽  
Female Ratio ◽  
Medical College ◽  
Neck Masses ◽  
Male Female Ratio ◽  
Neck Anatomy ◽  
Malignant Lesions ◽  
Diagnostic Modalities

Background: Tumors of neck are especially interesting to surgeons because of complex neck anatomy and difficult differential diagnosis. The aim is to study different type of lateral neck masses excluding thyroid and salivary swellings, there relation with age and se, there clinical features, presentation, and complications, diagnostic modalities and treatment according to the diagnosis and miscellaneous and rare lumps in the neck.Methods: The study was conducted at Shri Vasantrao Naik Government Medical College, Yavatmal, Maharashtra, India from January 2012 to December 2015. In cases of tubercular lympahdenopathy, patients are treated with antitubercular chemotherapy regime DOT’s. In cases of malignant secondaries in neck, patients were offered radical neck dissection, radical radiotherapy or neoadjuvant chemotherapy followed by neck dissection.Results: Total 228 patients are studied. 74.56% were benign and 25.44% were malignant. Most common age group affected was 11-20 years. Malignant lesions were more common after 50 years. Male female ratio was nearly equal. Most common lesion overall was tubercular lymphadenopathy followed by malignant lymph nodes.Conclusions: Lymphadenopathy predominated lateral neck swellings of which tubercular lymphadenopathy found to be commonest followed by malignant secondries. Tubercular infections are common during 1st and 2nd decade, while malignant lesions after 5th decade. FNAC was most common and most effective investigation. Treatment varies according to the cause of lateral neck mass.

scholarly journals Clinicopathological study of sinonasal masses

1970 ◽  
Vol 16 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Abu HenaMohammad Parvez Humayun ◽  
AHM Zahurul Huq ◽  
SM Tarequddin Ahmed ◽  
Md Shah Kamal ◽  
Kyaw Khin U ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Malignant Lesion ◽  
Malignant Tumour ◽  
Neck Surgery ◽  
Female Ratio ◽  
Medical College ◽  
Male To Female ◽  
Study Setting ◽  
Head Neck Surgery ◽  
Head Neck

Objective: To observe the incidence, clinical presentation and to perform comparative studyof different sinonasal masses. Study design: Prospective study. Setting: Department ofotolaryngology and Head-Neck Surgery & ENT OPD of Chittagong Medical College Hospital.Patients & methods: 50 patients are included in this study (39 male & 11 female) between theages of 3 years and 80 years who were treated between August 2006 to January 2007. Studybased on history, clinical, radiological, laboratory and histopathological examination. Results:Mean age for male was 35.12 years and for female was 22.63 years. Male to female ratio was3.5:1. Highest frequency was noted in second decade. Most of patient (78%) were from poorclass. Frequency of inflammatory nasal masses were more in second decade, benign tumourin fourth and fifth decade, malignant tumour in second decade (OAN & NHL) and fifth andsecond decades (others). Rhinosporidiosis were most frequent inflammatory nasal masses.Nasal obstruction was the commonest and orbitus symptoms were less frequent symptoms.But orbital symptoms were more prevalent in malignant lesion. Conclusion: sinonasal massesare found in all age group. Rhinosporidiosis are appearing to be the commonest nasal masses.The prevalence of nasal polyp is also high. Among the malignant sinonasal masses thepercentage of squamous cell carcinoma is high.DOI: 10.3329/bjo.v16i1.5776Bangladesh J Otorhinolaryngol 2010; 16(1): 15-22

scholarly journals Salivary gland tumours - a three years experience at King Edward Medical College, Lahore

2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Asmaa Qureshi ◽  
Khalilur Rehman ◽  
Sohail Husain ◽  
Nasirul Hasan Khawaja ◽  
Ghulam Rasood Qureshi ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Single Case ◽  
Malignant Neoplasms ◽  
Salivary Gland Tumours ◽  
Medical College ◽  
Common Location ◽  
Female Predominance

Salivary gland tumours make an important part of oral & maxillofacial pathology. Only few studies have been done in Pakistani population. The aim of this study was to describe morphological types of salivary gland tumours diagnosed at King Edward Medical College/ Mayo Hospital, Lahore during the years 1999-2001 and to compare their demographic data with those previously published. Material & Methods: This descriptive cross-sectional study was carried out at King Edward Medical College/ Mayo Hospital, Lahore. It reports 117 cases of salivary gland tumours diagnosed at Pathology Department during 1999-2001. Results: Of the 128 specimens of salivary glands, 117(91.4%) were confirmed as salivary neoplasms. Out of them, 62.7% were benign and 37.6% malignant and a slight female predominance (58.1%) was found. The most common location was the parotid gland (65.8%) followed by minor salivary glands (19.6%). Majority oft he t tumours was diagnosed during 3rd to 5 decades of life. Median age for benign tumours was 33 years (range 1-78) and a female predominance (58.9%) was seen again. Median age for malignant neoplasms was 45 years (range 9-70) with a female predilection ( 56.8%). However, 4 out o f 5 patients with Warthin`s tumour were men. Pleomorphic adenoma was the most frequent tumour (51.3%), followed by mucoepidermoid carcinoma (25.6%), adenoid cystic carcinoma (7.7)), Warthin`s tumour (4.3%) and monomorphic adenoma (2.6%). Two cases each of oncytoma & adenocarcinoma were recorded. Rare categories (single case each) of salivary tumours included lipoma, acinic cell carcinoma, basal cell adenoma, capillary haemangioma, metastatic carcinoma and non Hodgkin`s lymphoma. Conclusion: The principal site of salivary tumours was the parotid gland and females were most affected. Pleomorphic adenoma was the most frequent finding. The results of this study are comparable with other studies.

scholarly journals Conjunctival Lesions: A 5-Year Basic Demographic Data and Clinicopathological Review in a Tertiary Eye Care Hospital

2021 ◽  
Author(s):  
Hind M. Alkatan ◽  
Khalid M. Alshomar ◽  
Hala A. Helmi ◽  
Wajda M. Alhothali ◽  
Abdulaziz M. Alshalan
Keyword(s):  
Wide Spectrum ◽  
Care Center ◽  
Demographic Data ◽  
Tertiary Care ◽  
Malignant Lesion ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
Adult Males ◽  
Duration Of Symptoms ◽  
Malignant Lesions

Abstract Background Conjunctival lesions are common with a wide spectrum of benign, premalignant, and malignant lesions. Few histopathological studies have been conducted on conjunctival lesions with variable designs and results. Our aim in this study is to provide information on common conjunctival lesions seen in an ophthalmology tertiary care center in Saudi Arabia. Methods A retrospective, observational study of all consecutive conjunctival tissue specimens sent for histopathological assessment to the pathology department from 2015 to 2019 were analyzed. Clinical data were collected from medical records, and the histopathological slides were reviewed by a single pathologist. Results A total of 110 conjunctival specimens from 108 patients were included (mean age: 53 years, 67 males and 43 females). Bilateral involvement was mostly found in inflammatory lesions (40%). Most lesions were benign (91%), with a significantly longer duration of symptoms in malignant lesions (p = 0.036*). The clinical diagnosis matched the final histopathological diagnosis in 75.5% of the total specimens. The most frequent category of benign lesions was fibrodegenerative and proliferative lesions (53.6%), with a significantly higher prevalence among adult males (p < 0.001). Melanocytic lesions were more common in children (33.3%) than adults (9.8%), and the mean age of children was significantly lower (p = 0.013). The most frequent malignant lesion was ocular surface squamous neoplasia (50%), with equal prevalence among males and females. The overall outcome was favorable in 89.4% and unfavorable in 10.6%, mostly due to surgical complications, further progression of the lesion, or recurrence. Conclusion This study shows variability in the frequency of conjunctival lesions based on gender, age, geographical, racial, and environmental factors. There has been a shift in the gender-based prevalence of ocular squamous neoplasia over the last three decades, probably due to a change in lifestyle.

scholarly journals Prevalence of Anti-Red Cell Antibodies in Repeatedly Transfused Patients

2019 ◽  
Vol 14 (1) ◽  
pp. 73-77
Author(s):  
Masuma Ahmed Salsabil ◽  
Ashesh Kumar Chowdhury ◽  
Debashish Saha ◽  
Arif Ahmed Khan ◽  
Sazia Sultana
Keyword(s):  
Haemolytic Anaemia ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Red Cell ◽  
Cross Sectional ◽  
Transfusion Therapy ◽  
Female Ratio ◽  
Medical College ◽  
Male Female Ratio ◽  
Immune Haemolytic Anaemia

Introduction: The development of anti-RBC antibodies (alloantibodies and/or autoantibodies) can significantly complicate transfusion therapy, particularly in patients needed repeated transfusion. Objectives: To find out the prevalence of alloantibodies and autoantibodies in repeatedly transfused patients so that serious hazards due to immune reaction may be avoided. Materials and Methods: This descriptive cross-sectional study was carried out in Department of Immunology, BIRDEM and Armed Forces Institute of Pathology (AFIP) during the period of July 2015 to June 2016. Total 370 patients who had received at least five units of transfusions were enrolled in this study but known patients of auto immune haemolytic anaemia, patients in whom antibody was previously detected and pregnant women were excluded from the study. Blood grouping and Direct Anti-globulin Test (DAT) were performed with cell suspension using a poly-specific Coombs reagent. In cases of a positive DAT, further investigation using specific monoclonal reagents to detect IgG or a complement (C3d) was carried out. Serum was used to detect red cell alloantibodies using standard blood bank methods. Antibody identification was performed in antibody screening positive samples using red cell Identicells. Results: Maximum 132 (35.7%) patients were in the age group 1-10 years. The male-female ratio was 1.2:1. Among 370 total patients 290 were HHA and 80 were non-HHA. Antibody was detected in only 17(4.59%) patients. Among the Hereditary Haemolytic Anaemia (HHA) patients it was 11 (3.79%) but among the non-HHA patients it was 6(7.5%). Out of 8 auto-antibodies, 5 were anti IgG followed by 3 were anti C3d. Out of 14 alloantibodies, 4(28.6%) were anti E, 3(21.4%) were anti K and in 3(21.4%) cases specificity of alloantibody was not detected. Conclusion: Prevalence of anti-RBC antibodies was not so uncommon in multiple transfused patients. Journal of Armed Forces Medical College Bangladesh Vol.14(1) 2018: 73-77

scholarly journals Diagnostic diversities of Clear Fluid encountered during Fine needle aspiration cytology with an analysis of various variables.

2019 ◽  
Vol 18 (4) ◽  
pp. 753-755
Author(s):  
RS Minz ◽  
A Adhikari ◽  
S Biswas ◽  
RN Ray ◽  
K Bose ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Incidental Finding ◽  
Medical Science ◽  
Malignant Lesion ◽  
Needle Aspiration ◽  
The Body ◽  
Epidermal Cyst ◽  
Clear Fluid ◽  
Female Ratio ◽  
Fine Needle

Background: Incidental finding of clear fluid during fine needle aspiration (FNA) is not rare in day to day practice of cytology. Though clear in appearance, cells obtained from it may yield a diverse diagnosis ranging from an inconclusive opinion to a malignant lesion. So, clear fluid is not non-significant always; lack of proper processing and examination may prove fatal to a patient. Aim: To evaluate the diverse diagnosis of clear fluid. Materials and methods: During a period of three years, hundred and seven cases which yielded clear fluid during FNAC from different parts of the body were studied. Direct and indirect smears (wherever applicable) was prepared, stained and examined microscopically. Results: Of these 107 cases of clear fluid, Male: Female ratio was 1: 1.6. Maximum cases - 55 (51.40%) was found in the age group 21 to 40 years. Trunk held the most number of lesions - 54 cases (50.46%). FNA results were interpreted as inconclusive in 19 cases (17.76%), benign in 84 cases (78.50%), suspicious in 01 case (0.93%) and malignant in 03 cases (2.80%). Epidermal cyst was the most common benign lesion - 16 cases (14.95%). Malignant lesions found were papillary carcinoma of thyroid, carcinoma of breast and metastatic squamous cell carcinoma – one case each. Conclusion: Our study emphasizes on the importance of proper examination of clear fluid as it may prove helpful in an undiagnosed case of malignancy and it may also improvise the learning of young pathologists. Bangladesh Journal of Medical Science Vol.18(4) 2019 p.753-755

scholarly journals Socio-demographic Characteristics of Patients with Tuberculosis Spine in Bangladesh

2017 ◽  
Vol 3 (1) ◽  
pp. 3-5 ◽  
Author(s):  
Md Shafiul Alam ◽  
Md Abdus Salam ◽  
Tayseer Farzana ◽  
ASM Raushan Newaz ◽  
Md Saiful Islam
Keyword(s):  
Spinal Tuberculosis ◽  
Demographic Characteristics ◽  
Age Group ◽  
College Hospital ◽  
Female Ratio ◽  
High Class ◽  
Medical College ◽  
Class Society ◽  
Male Female Ratio ◽  
The Mean

Background: Spinal tuberculosis is more frequently reported in developing countries.Objective: The purpose of the present study was to see the socio-demographic characteristics of spinal tuberculosis patients.Methodology: This study was carried out in the Department of Neurosurgery, Dhaka Medical College Hospital during the period of January 2002 to December 2004 to elucidate the effectiveness of surgical and conservative treatment of the tuberculosis of the spine. For this purpose, a total number of 50 consecutive cases admitted during the study period with tuberculosis of the spine supported by investigations were included in this study.Result: The mean age of the patients was 25.4 years and ranged from 7 years to 68 years. The highest incidence of tuberculosis of the spine was found in age group between 11 to 20 years and 70% of the patients were under 30 years of age. Incidence of tuberculosis of this spine was more in male (62%) in comparison to female (3 8%) with a male female ratio of 1.63:1. In this study most of the patients came from low class society (66%) followed by middle class (28%) and high class (6%) respectively.Conclusion: Spinal TB more frequently occurs among the young age group with a male predominance.Bangladesh Journal of Infectious Diseases 2016;3(1):3-5

scholarly journals Spectrum of primary salivary gland tumors with special emphasis on their management and outcome at a rural tertiary care centre

2020 ◽  
Vol 7 (3) ◽  
pp. 818
Author(s):  
Dwaipayan Samaddar ◽  
Jaya B. Samaddar ◽  
Ahmad M. Aziz
Keyword(s):  
Salivary Gland ◽  
Tertiary Care ◽  
Study Data ◽  
Salivary Gland Tumors ◽  
P Value ◽  
Malignant Tumours ◽  
Tertiary Care Centre ◽  
Female Ratio ◽  
Medical College ◽  
Benign Tumours

Background: Salivary gland tumors (SGT) are uncommon tumors of diverse histopathology accounting for <2% of all neoplasms. Early diagnosis differentiates between benign and malignant SGT and less extensive surgical procedure can be performed. The objective is to study the spectrum of primary SGT with special emphasis on their distribution, treatment and outcome at a rural tertiary care centre.Methods: A prospective observational study was conducted on 30 consecutive primary SGT patients attending the Departments of Surgery and Otorhinolaryngology of North Bengal Medical College and Hospital over a period of one and half years. All patients were clinically evaluated, investigated, treated accordingly and followed up during the period of study. Data was collected and compiled in Excel sheet and analysed using GraphPad Software and GraphPad QuickCalcs 2018 (San Diego, CA). A p value <0.05 was considered statistically significant.Results: Maximum patients (83.3%) were in the age range of 31-60 years. The male to female ratio was 1:4 for benign tumours and 1:1 for malignant tumours. Malignant cases were 66.67%. Involvement of parotid gland was the commonest (43.3%) and mostly presented with swelling (73.3%). Pleomorphic salivary adenoma was the commonest benign tumor (33.3%) and mucoepidermoid carcinoma was the commonest malignant tumor (16.7%). Permanent facial palsy was observed in 2 (9.5%) and recurrence in 4 patients (19%).Conclusions: SGT are rare and present in various modes. Malignant cases were singularly more in this study.

scholarly journals Outcome of Injection Sclerotherapy for First Degree and Second Degree Haemorrhoids– A Study of 50 Cases

2016 ◽  
Vol 12 (2) ◽  
pp. 98-101
Author(s):  
Md Ershad Ul Quadir ◽  
Md Mahbubur Rahman ◽  
Md Tanvirul Islam ◽  
SM Shakhawat Hosssain
Keyword(s):  
Symptomatic Relief ◽  
Digital Rectal Examination ◽  
Cost Effective ◽  
Armed Forces ◽  
Injection Sclerotherapy ◽  
Female Ratio ◽  
Medical College ◽  
Number Of Patients ◽  
Male Female Ratio ◽  
Second Degree

Introduction: Haemorrhoid is the frequent problem in clinical practice of general surgery. Haemorrhoids are dilatation and tortuosity of rectal veins affecting almost 4.5% of the population. Various operative and non operative therapeutic options are in practice to treat haemorrhoids, yet none has been proven cent percent effective. Sclerotherapy is a simple, safe and cost effective procedure that is widely practiced globally to treat haemorrhoids. Many sclerosants are being used with variable efficacies. Objective: To evaluate the outcome of injection Sclerotherapy in first degree and second degree haemorrhoids. Materials and Methods: Fifty patients of both gender having haemorrhoids who attended Outpatient Department (OPD) at BNS Patenga from September 2013 to August 2014 were included in this study. On the basis of history, patients were selected for Digital Rectal Examination (DRE) and proctoscopic examination to confirm the diagnosis. Sclerotherapy was repeated at interval of 6 weeks till symptomatic relief was achieved. Maximum 3 sittings of sclerotherapy were given. Patients were followed up at 3 months interval for 1 year. Results: This prospective study was conducted on 50 cases of first degree and second degree Haemorrhoids. The highest number of patients 21(42%) were in the age group of 21-30 years with majority 38(76%) being male. Male female ratio was 3.16: 1. All the patients presented with painless per-rectal bleeding. Satisfactory results were observed in 29(58%) patients of whom 20(40%) patients were having first degree haemorrhoids and 9(18%) patients were having second degree haemorrhoids. Sclerotherapy was more effective in first degree compared to second degree haemorrhoids patients. Conclusion: Injecting Sclerotherapy is a suitable office procedure for treatment of haemorrhoids. The method is easy, convenient, cheap, well accepted and comfortable for patient. More or less there are no complications and the result is also satisfactory. Journal of Armed Forces Medical College Bangladesh Vol.12(2) 2016: 98-101

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