scholarly journals An Emerging, Neglected and Underestimated Zoonotic Parasitic Ocular Infestation: A Comprehensive Review on Thelaziasis

2021 ◽  
Vol 9 (02) ◽  
pp. 82-88
Author(s):  
Rajeshwar Reddy Kasarla ◽  
Shristi Raut Adhikari ◽  
Kripa Ghimire ◽  
Laxmi Pathak
Keyword(s):  
Rural Communities ◽  
Scientific Information ◽  
Clinical Manifestations ◽  
Signs And Symptoms ◽  
Intermediate Hosts ◽  
Low Socioeconomic ◽  
Body Sensation ◽  
Close Proximity ◽  
Corneal Opacities ◽  
Accidental Host

Human thelaziasis is an emerging insect-borne zoonotic ocular parasitic infestation, occur more commonly in rural communities with poor living and low socioeconomic living, and mainly affects the children and old age people, where humans live in close proximity with animals. Human thelaziasis is caused by both Thelazia callipaeda and Thelazia californiensis. T. callipaeda lives under the eye lids, nictitating membranes, orbit, conjunctival sac, lachrymal glands, and lacrimal ducts of cats, dogs, rabbits, horses, cattle, deer, badgers, monkeys, wolves, foxes (definitive hosts) and man being an accidental host. The vectors (intermediate hosts) are non-biting, tear-seeking, diptera flies of family Drosophilidae (fruit flies) Phortica variegata, which feeds on tears of their definitive hosts, including humans. Clinical manifestations include conjunctivitis, lacrimation, itching or pain with foreign body sensation, epiphora, follicular hypertrophy, and less often with severe signs and symptoms such as keratitis, photophobia, ectropion, corneal opacities (due to the migration of worm across the cornea), floaters within the eye chamber leading to visual impairment/blindness. The knowledge and scientific information on human thelaziasis is still unknown or relatively limited to many ophthalmologists and clinicians, and received little attention; hence this comprehensive and systematic review of human thelaziasis, is undertaken to highlight its importance and further research.

scholarly journals Severe Ocular Surface abnormalities in a child and Ectodermal Dysplasia: A Case Report.

2019 ◽  
Vol 7 (7) ◽  
pp. 2845
Author(s):  
Shailender Minhas ◽  
Rajeev Tuli ◽  
Gaurav Sharma
Keyword(s):  
Case Report ◽  
Ectodermal Dysplasia ◽  
Systemic Disease ◽  
Clinical Manifestations ◽  
Signs And Symptoms ◽  
Abnormal Development ◽  
Body Sensation ◽  
Younger Age ◽  
The Family

Ectodermal Dysplasia is a disorder that occurs due to abnormal development of at least two major ectodermal derivatives in the developing embryo. Author report the case of a 10 year old male child who was referred to our department with complaints of absent sweating, foreign body sensation and watering in both eyes for past few months. The family history could be traced to four generations and there was an observed trend of increase in severity of signs and symptoms occurring at younger age.  The purpose of this case report is to create awareness in the Ophthalmic community about the diagnosis and clinical manifestations of the disorder. This case highlights the role of multidisciplinary approach for management of systemic disease, genetic evolution of affected individual and carriers and genetic counseling.

To evaluate the clinical efficacy of Palash Mula Arka in Pittaja Netrabhishyanda.

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Yuwaraj D. Kale ◽  
Sarika Choure
Keyword(s):  
Foreign Body ◽  
Modern Science ◽  
Signs And Symptoms ◽  
Burning Sensation ◽  
Trial Group ◽  
Inflammatory Condition ◽  
Conjunctival Hyperemia ◽  
Bacterial Conjunctivitis ◽  
Body Sensation ◽  
Acute Bacterial Conjunctivitis

Abhishyanda is one of the Sarvagata Vyadhi mentioned by Acharya Sushruta. In modern science, signs and symptoms of Netrabhishyanda may be correlated with conjunctivitis, which is the inflammatory condition of conjunctiva. Kavala Dharana, Dhumrapana, Aschyotana, Sechana Putapaka etc. are various suggested regimens in Ayurvedic texts for the treatment of Netrabhishyanda. Considering this effectiveness of Palasha as mentioned by Acharya Sushruta, it is planned to study the use of Palasha Mula Arka Aschyotana in Pittaja Netrabhishyanda. 60 patients having classical signs and symptoms of Pittaja Abhishyanda (Acute Bacterial Conjunctivitis) as per Ayurvedic and modern texts were selected for the study. After completion of therapy, mean Conjunctival hyperemia was reduced to 0.2167 ± 0.4086 in Control and 0.5667 ± 0.5040 in Trial Group. Palasha Mula Arka was found effective in reduction in conjunctival hyperemia, watering and the number of culture colonies, it was also found effective in burning sensation, discharge, foreign body sensation and photophobia.

scholarly journals Behavioral and Social Considerations

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 855-855
Author(s):  
Lisa Barry
Keyword(s):  
Health Status ◽  
Low Socioeconomic Status ◽  
Clinical Manifestations ◽  
Individual Variability ◽  
Underrepresented Minority ◽  
Social Dimensions ◽  
Early Life Adversity ◽  
Low Socioeconomic ◽  
Rate Of Decline ◽  
Multidimensional Health

Abstract Cognitive, behavioral and social dimensions also demonstrate increasing heterogeneity with aging. For example, a longitudinal study of over 1,000 clergy revealed increasing heterogeneity in cognitive function and rate of decline with aging. Moreover, studies of individuals with probable Alzheimer’s disease have shown heterogeneity in terms of clinical manifestations and rates of cognitive decline. Older adults also demonstrate greater heterogeneity in mood, anxiety, and the nature and patterns of symptoms over time. Heterogeneity of overall health status increases with aging, as does reported quality of life. Health and Retirement Study (HRS) data have shown that low socioeconomic status or being an underrepresented minority are both associated with greater intra-individual variability in health status in old age, with greatest differences seen in Hispanics. Finally, early life adversity can contribute to heterogeneity of multidimensional health trajectories even in late life.

POLYNEURITIS IN CHILDREN

PEDIATRICS ◽  
1958 ◽  
Vol 22 (5) ◽  
pp. 972-990
Author(s):  
Niels L. Low ◽  
Julia Schneider ◽  
Sidney Carter
Keyword(s):  
Clinical Picture ◽  
Cranial Nerve ◽  
Clinical Manifestations ◽  
Signs And Symptoms ◽  
Severity Of The Disease ◽  
Clinical Records

Polyneuritis in children is becoming more common. The clinical picture is variable; it may be manifested by motor and sensory findings, or by a combination of peripheral and cranial nerve signs and symptoms. The etiology is usually obscure. The pathologic picture varies with the severity of the disease and differs according to the stage at which the patient dies, but all fatal cases show the same main characteristic changes. Clinical records of 30 cases, 17 boys and 13 girls from 17 months to 16 years of age, are reviewed. The clinical manifestations, course and treatment are described.

scholarly journals Prevalence and Correlates of Alcohol Use among a Sample of Nigerian Semirural Community Dwellers in Nigeria

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Victor Olufolahan Lasebikan ◽  
Bolanle Adeyemi Ola
Keyword(s):  
Rural Communities ◽  
Alcohol Use ◽  
Health Risk ◽  
Risk Scores ◽  
Low Socioeconomic ◽  
Care Services ◽  
Associated Risk Factors ◽  
Substance Involvement ◽  
Current Alcohol ◽  
Community Dwellers

Objective. To determine the prevalence and correlates of alcohol use among a sample of Nigerian semirural community dwellers in Nigeria.Methods. In a single arm nonrandomized intervention study, the assessment of baseline hazardous and harmful alcohol use and associated risk factors was conducted in two semirural local government areas of Oyo State, Nigeria, with the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST). Participants included 1203 subjects 15 years and older, recruited between October 2010 and April 2011. ASSIST score of 0–10 was classified as lower risk scores, 11–26 as moderate risk, and 27+ as high risk.Results. Prevalence of lifetime alcohol use was 57.9% and current alcohol use was 23.7%. Current alcohol use was more prevalent among the younger age groupp=0.02, male genderp=0.003, unmarriedp<0.01, low educational levelp=0.003, low socioeconomic classp=0.01, unemployedp<0.001, and the Christiansp<0.01. Of the current drinkers, the majority (69.1%) were at either moderate or high health risk from alcohol use.Conclusion. Alcohol consumption is prevalent in semirural communities in Nigeria and the majority of these drinkers are at moderate or high health risk. Screening, brief intervention, and referral for treatment for unhealthy alcohol use should be integrated into community care services in Nigerian rural communities.

scholarly journals Renal involvement in human rabies: clinical manifestations and autopsy findings of nine cases from northeast of Brazil

2005 ◽  
Vol 47 (6) ◽  
pp. 315-320 ◽  
Author(s):  
Elizabeth De Francesco Daher ◽  
Geraldo Bezerra da Silva Júnior ◽  
Marúsia Thomaz Ferreira ◽  
Fernando Antonio de Sousa Barros ◽  
Tiago Magalhães Gurgel ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Renal Involvement ◽  
Clinical Manifestations ◽  
Signs And Symptoms ◽  
Hemodynamic Instability ◽  
Human Rabies ◽  
Tubular Necrosis ◽  
Post Mortem Findings ◽  
Histopathologic Findings

A retrospective study was conducted in nine patients with rabies admitted to a hospital of Fortaleza, Brazil. Autopsy was performed in all cases. The ages ranged from three to 81 years and six were males. They all were bitten by dogs. The time between the accident and the hospital admission ranged from 20 to 120 days (mean 45 ± 34 days). The time until death ranged from one to nine days (mean 3.3 ± 5.5 days). The signs and symptoms presented were fever, hydrophobia, aerophobia, agitation, disorientation, dyspnea, sialorrhea, vomiting, oliguria, sore throat, pain and hypoesthesia in the site of the bite, headache, syncope, cough, hematemesis, mydriasis, hematuria, constipation, cervical pain and priapism. In three out of six patients, there was evidence of acute renal failure, defined as serum creatinine > 1.4 mg/dL. The post-mortem findings in the kidneys were mild to moderate glomerular congestion and mild to intense peritubular capillary congestion. Acute tubular necrosis was seen in only two cases. This study shows some evidence of renal involvement in rabies. Histopathologic findings are nonspecific, so hemodynamic instability, caused by autonomic dysfunction, hydrophobia and dehydration must be responsible for acute renal failure in rabies.

scholarly journals Observation of initial clinical manifestations and repercussions from the treatment of 314 human injuries caused by black sea urchins (Echinometra lucunter) on the southeastern Brazilian coast

2012 ◽  
Vol 45 (3) ◽  
pp. 390-392 ◽  
Author(s):  
Vidal Haddad Junior
Keyword(s):  
Foreign Body ◽  
Black Sea ◽  
Sea Urchins ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Signs And Symptoms ◽  
Early Observation ◽  
The Black Sea ◽  
Brazilian Coast ◽  
Marine Animals

INTRODUCTION: Injuries caused by sea urchins are the most common caused by marine animals in humans in Brazil, with the black sea urchin (Echinometra lucunter) causing the most injuries to bathers. METHODS: This study observed 314 human wounds with emphasis on the early observation of clinical signs and symptoms and their implications on the recommended treatment. RESULTS: All the injuries were caused by black sea urchins and were observed in bathers. The lesions and the pain were associated with penetration of the spines; there was no early inflammation or pain without pressure on the wounded places. Complications arising from this kind on injury, including infections and foreign body granulomas, are associated with the permanence of the spines in the wounds. CONCLUSIONS: The study confirmed that this kind of injury is the most common accident caused by aquatic animals in Brazil. The main therapeutical recommendation is early removal of the spines to prevent late complications, such as infections and the formation of foreign body granulomas.

scholarly journals Behcet’s Disease: An In-depth Review About Pathogenesis, Gastrointestinal Manifestations And Management

2021 ◽  
Author(s):  
Anthony Nguyen ◽  
Shubhra Upadhyay ◽  
Muhammad Ali Javaid ◽  
Abdul Moiz Qureshi ◽  
Shahan Haseeb ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Signs And Symptoms ◽  
Vascular Disorder ◽  
Robust Algorithms ◽  
Behcet's Disease ◽  
Relapsing Remitting

Background: Behcet’s Disease (BD) is a complex inflammatory vascular disorder that follows a relapsing-remitting course with diverse clinical manifestations. The prevalence of the disease varies throughout the globe and targets different age groups. There are many variations of BD, however, intestinal BD is not only more common but has many signs and symptoms. Summary: BD is a relapsing-remitting inflammatory vascular disorder with multiple system involvement, affecting vessels of all types and sizes that targets young adults. The etiology of BD is unknown but many factors including genetic mechanisms, vascular changes, hypercoagulability and dysregulation of immune function are believed to be responsible. BD usually presents with signs and symptoms of ulcerative disease of the small intestine; endoscopy being consistent with the clinical manifestations. The mainstay of treatment depends upon the severity of the disease. Corticosteroids are recommended for severe forms of the disease and aminosalicylic acids are used in maintaining remission in mild to moderate forms of the disease. Key messages: In this review, we have tried to summarize in the present review the clinical manifestations, differential diagnoses and management of intestinal BD. Hopefully, this review will enable health policymakers to ponder over establishing clear endpoints for treatment, surveillance investigations and creating robust algorithms.

scholarly journals Microanálisis comparado de la transición demográfica en tres islas de las Azores, siglos XVIII-XX: Diferencias en el pasado, semejanzas en el presente.

2021 ◽  
Author(s):  
Maria Norberta Amorim ◽  
Francisco J. Marco Gracia ◽  
Filipe Salgado
Keyword(s):  
Rural Communities ◽  
Demographic Transition ◽  
Transition Process ◽  
Population Pressure ◽  
Fertility Level ◽  
Birth Intervals ◽  
Age At Marriage ◽  
Several Variables ◽  
Close Proximity ◽  
Lower Fertility

The demographic transition is a global phenomenon. However, previous studies have demonstrated the existence of differences in its development between areas that are in close proximity. The aim of this article is to compare the process of demographic transition in the rural communities of three islands in the archipelago of the Azores (Pico, Flores and Corvo) using life course data for more than 250 years. Throughout the article several variables related to nuptiality, fertility, mortality and mobility have been analysed. Our results show clear differences between communities prior to the demographic transition and, to a lesser extent, during the demographic transition process. The island of Flores, for instance, has historically presented higher fertility because of a lower age at marriage. The island of Pico, on the other hand, had a lower fertility level, higher age at marriage and longer birth intervals. During the demographic transition, infant mortality first began to fall in Flores, therefore increasing population pressure. Since 1840, international migration and the abandonment of children served as mechanism to reduce the population pressure.

scholarly journals High Anti-HCV Seroprevalence and Low Performance of ICT Strip in Diagnosing Hepatitis C Virus Infection in Children in Enugu Metropolis

2018 ◽  
Vol 12 (1) ◽  
pp. 149-156
Author(s):  
Maryann C. Ezeilo ◽  
Godwill A. Engwa ◽  
Romanus I. Iroha ◽  
Damian N. Odimegwu
Keyword(s):  
Risk Factors ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Test Performance ◽  
Clinical Manifestations ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Hcv Infection ◽  
Enzyme Linked Immunosorbent Assay ◽  
Cross Sectional

Background:The lack of a vaccine for Hepatitis C virus (HCV) places children at a high risk of contracting the infection. It becomes necessary to accurately diagnose this infection for proper treatment as well as identifying potential risk factors for effective management.Aim:This study was conceived to assess the test performance of the commonly used Immunochromatographic test (ICT) strip and identify the associated clinical manifestations and risk factors of HCV in children in Enugu Metropolis.Method:A cross-sectional study involving randomly selected 270 children below six years of age was conducted in Enugu Nigeria. The subjects were screened for anti-HCV by ICT and Enzyme-Linked Immunosorbent Assay (ELISA) and the demographic, signs and symptoms and risk factors were collected.Results:A total of 50 out of 270 children were positive for anti-HCV with a seropositivity of 18.5%. ICT strip had a very low sensitivity of 38.00% with an accuracy of 88.52% in detecting anti-HCV. The presence of dark urine was associated (p= 0.01) with HCV infection.Conclusion:A seroprevalence of 18.5% of Anti-HCV was found in children below six years old in Enugu metropolis and the performance of ICT in diagnosing HCV infection was poor compared to ELISA.

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