scholarly journals The problem of combined diseases in the reproductive system of the women

2019 ◽  
Vol 23 (4) ◽  
pp. 733-739
Author(s):  
O.Yu. Kruk
Keyword(s):  
Quality Of Life ◽  
Mammary Gland ◽  
Theoretical Analysis ◽  
Effective Treatment ◽  
Reproductive System ◽  
Mammary Glands ◽  
Diagnosis And Treatment ◽  
Urgent Problem ◽  
Treatment Algorithms

Annotation. This article highlights the urgent problem of combined diseases of women's reproductive system. On the basis of theoretical analysis, generalized statistics for recent years are presented. The modern concepts of pathogenesis of diseases of the uterus and mammary glands, their correlation, as well as models of diagnosis and treatment are considered. Indeed, a more in-depth understanding of the problems of the combined pathology of the woman’s reproductive system (diseases of the uterus, ovaries, mammary gland), namely etiopathogenesis, diagnostic and treatment algorithms, will reduce the incidence of women of reproductive and perimenopausal age, as well as improve their quality of life. Only having the fullness of information about the state of the reproductive system of women, the doctor is able to prescribe thoughtful and effective treatment.

Clinical case of a comorbid patient with arterial hypertension

2020 ◽  
pp. 31-39
Author(s):  
Ella Polozova ◽  
Vsevolod Skvortsov ◽  
Olga Radaykina ◽  
Mariya Narvatkina ◽  
Anastasiya Seskina ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Arterial Hypertension ◽  
Clinical Picture ◽  
Clinical Case ◽  
Diagnosis And Treatment ◽  
The Moment

The widespread prevalence of comorbid pathology determines the relevance of this problem. Comorbid pathology due to the interaction of diseases, drug pathomorphism, age characteristics of the patient, significantly changes clinical picture and course of the main nosology, affects severity of complications and their nature, significantly affects quality of life and prognosis of patients. Diagnosis and treatment of many diseases is complicated in the conditions of comorbidity. The article presents a clinical case of a comorbid patient with arterial hypertension from the moment of exposure to risk factors and ending with the formation of many concomitant diseases, as an example of trans-nosological comorbidity.

scholarly journals Quality of life in patients with no-option critical limb ischemia underlines the need for new effective treatment

2010 ◽  
Vol 52 (4) ◽  
pp. 843-849.e1 ◽  
Author(s):  
Ralf W. Sprengers ◽  
Martin Teraa ◽  
Frans L. Moll ◽  
G. Ardine de Wit ◽  
Yolanda van der Graaf ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Effective Treatment ◽  
Critical Limb Ischemia ◽  
Limb Ischemia

Cytomegalovirus Retinitis: Diagnosis and Treatment

1993 ◽  
Vol 4 (6) ◽  
pp. 322-325 ◽  
Author(s):  
Hunter Maclean ◽  
Baljean Dhillon
Keyword(s):  
Quality Of Life ◽  
Correct Diagnosis ◽  
Cytomegalovirus Retinitis ◽  
Morbidity And Mortality ◽  
Diagnosis And Treatment ◽  
Hiv Positive ◽  
Pathogenic Organism

Cytomegalovirus (CMV) is a non-pathogenic organism in the immunocompetent, but is a major cause of morbidity and mortality amongst patients with AIDS, and the retina is the commonest site of infection1. If left untreated, patients with CMVR will develop disease in their second eye and ultimately become blind2. However, with correct diagnosis and treatment useful vision can be maintained in the majority of cases. Fifteen to 20% of patients with AIDS will contract cytomegalovirus retinitis (CMVR)3−7 and this may be the AIDS-defining diagnosis though more commonly it occurs months after the diagnosis of AIDS. Given the increasing number of HIV positive patients and their longer survival, it is likely that CMVR will become an increasingly prevalent condition. In these patients loss of sight from CMVR has devastating consequences in terms of loss of independence and quality of life and therefore ophthalmologists and physicians should be aware of the presenting characteristics of CMVR, be familiar with therapy and its complications, and be able to recognize relapsing infection.

scholarly journals Lipogranulomas of the mammary glands: diagnosis and treatment

2021 ◽  
Vol 70 (2) ◽  
Author(s):  
Natalia Cara ◽  
◽  
Veronica Svet ◽  
Ion Mereuta ◽  
◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adipose Tissue ◽  
Mammary Gland ◽  
Inflammatory Process ◽  
Pathological Condition ◽  
Scar Tissue ◽  
Mammary Glands ◽  
Diagnosis And Treatment ◽  
Breast Lesions ◽  
Fat Necrosis

Steatonecrosis of the mammary gland is necrosis of its adipose tissue, followed by replacement with scar tissue. Lipogranuloma is known as a benign inflammatory process, necrosis of breast fat occurs due to iatrogenic breast trauma. Most often, fatty necrosis is seen in women with large breasts – in women with small breasts, it develops much less often. It is important to diagnose lipogranulomas because it can often mimic breast cancer. Fat necrosis of the breast is a common pathological condition, with a wide variety of presentations on mammography, ultrasound and MRI. The incidence of fatty necrosis of the breast is estimated at 0.6%, representing 2.75% of all breast lesions.

scholarly journals Intraductal cystadenopapillomas of the mammary glands: diagnosis and treatment

2021 ◽  
Vol 70 (2) ◽  
Author(s):  
Diana Danilov ◽  
◽  
Veronica Svet ◽  
Ion Mereuta ◽  
◽  
...  
Keyword(s):  
Mammary Gland ◽  
Mammary Glands ◽  
Diagnosis And Treatment ◽  
Benign Tumors ◽  
Hormonal Changes ◽  
Basic Treatment

About one in two women has symptoms of breast formation. According to various data, the frequency of detection of benign pathologies of the mammary gland is much higher compared to the frequency of referring women to the doctor with these pathologies. Benign tumors of the mammary gland are characterized by a slow, expansive growth (compresses the neighboring tissue), are well encapsulated, most are the result of hormonal changes (hyperestrogenemia, hyperprolactinemia), after excision rarely recur, do not invade local tissues and do not metastasize to others. organs. The basic treatment is surgery – excision of the breast formations. Recurrences rarely occur, do not invade adjacent tissues and do not metastasize to other organs.

scholarly journals Primary and Secondary Cone Cell Death Mechanisms in Inherited Retinal Diseases and Potential Treatment Options

2022 ◽  
Vol 23 (2) ◽  
pp. 726
Author(s):  
Alicia A. Brunet ◽  
Alan R. Harvey ◽  
Livia S. Carvalho
Keyword(s):  
Quality Of Life ◽  
Cell Death ◽  
Effective Treatment ◽  
Treatment Options ◽  
Retinal Diseases ◽  
Potential Treatment ◽  
Cone Cell ◽  
Similarities And Differences ◽  
Cell Death Mechanisms

Inherited retinal diseases (IRDs) are a leading cause of blindness. To date, 260 disease-causing genes have been identified, but there is currently a lack of available and effective treatment options. Cone photoreceptors are responsible for daylight vision but are highly susceptible to disease progression, the loss of cone-mediated vision having the highest impact on the quality of life of IRD patients. Cone degeneration can occur either directly via mutations in cone-specific genes (primary cone death), or indirectly via the primary degeneration of rods followed by subsequent degeneration of cones (secondary cone death). How cones degenerate as a result of pathological mutations remains unclear, hindering the development of effective therapies for IRDs. This review aims to highlight similarities and differences between primary and secondary cone cell death in inherited retinal diseases in order to better define cone death mechanisms and further identify potential treatment options.

Quality of Life Following Management of Localized Prostate Cancer

2018 ◽  
Author(s):  
Louis A Aliperti ◽  
Martin G Sanda ◽  
Christopher P Filson
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Expectant Management ◽  
Diagnosis And Treatment ◽  
Urinary Tract Symptoms ◽  
Related Quality ◽  
Health Related ◽  
The Impact

With a long survivorship phase after diagnosis and treatment of prostate cancer, consideration of the impact of treatment on health-related quality of life (HRQOL) is critical. For men considering treatment of prostate cancer, the domains that are impacted include urinary, sexual, and bowel-related qualities of life. This review identifies aspects of tools measuring HRQOL and covers instruments used to measure quality of life following a diagnosis and treatment of prostate cancer. We review the impact associated with radical prostatectomy, radiation and brachytherapy, and observation on men diagnosed with prostate cancer and compare the effects that each management strategy has on sexual and urinary function. This review contains 3 figures, 5 tables, 44 references. Key Words: erectile dysfunction, expectant management, lower urinary tract symptoms, prostate cancer, radical prostatectomy, radiation therapy, quality of life, urinary incontinence

Bipolar Disorders and Their Clinical Management, Part II: Diagnosis, Differential Diagnosis, and Treatment

2019 ◽  
Author(s):  
Bernadette DeMuri-Maletic ◽  
Vladimir Maletic
Keyword(s):  
Quality Of Life ◽  
Bipolar Disorder ◽  
Differential Diagnosis ◽  
Bipolar Disorders ◽  
Psychosocial Interventions ◽  
Diagnosis And Treatment ◽  
Treatment Quality ◽  
Treatment Modalities ◽  
The Impact

Bipolar disorder is a biologically and phenotypically diverse disorder and its diagnosis and treatment provides a significant challenge to even the most seasoned clinician. We provide an update on the diagnosis and differential diagnosis of bipolar disorder, reflecting recent changes in DSM-5. Our review provides a succinct summary of the treatment literature, encompassing pharmacologic and psychosocial interventions for bipolar depression, mania/hypomania, mixed states, and prevention of disease recurrence. We provide a brief critical review of emerging treatment modalities, including those used in treatment resistance. Challenges involved in maintaining adherence are further discussed. Additionally, we review common treatment adverse effects and provide recommendations for proper side effect monitoring. There is evidence of significant functional impairment in patients with bipolar disorder and we conclude with a discussion of the impact of impairment on prognosis and quality of life. This review contains 4 figures, 8 tables, and 45 references. Key Words: bipolar disorders, differential diagnosis, maintenance pharmacotherapy, prognosis, psychosocial interventions, treatment, quality of life

scholarly journals Diagnosis and treatment of Paget's disease of bone: a mini-review

2013 ◽  
Vol 57 (8) ◽  
pp. 577-582 ◽  
Author(s):  
Bruno Ferraz-de-Souza ◽  
Pedro Henrique Silveira Correa
Keyword(s):  
Quality Of Life ◽  
Bone Metabolism ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Paget’S Disease Of Bone ◽  
Diagnosis And Treatment ◽  
Laboratory Evaluation ◽  
Sustained Remission ◽  
Paget's Disease Of Bone

Paget's disease of bone (PDB) is a chronic progressive disorder of bone metabolism that may go undetected for many years, and endocrinologists should be alert to its clinical signs and promptly diagnose and treat PDB before it results in irreversible complications, such as deformity, fracture or neurological sequelae. Most commonly, PDB is suspected upon the incidental finding of elevated serum alkaline phosphatase levels or a radiographic abnormality in an otherwise healthy individual above 55 years of age. Some of these individuals may have symptoms such as bone pain or enlargement with increased warmth. In general, a basic laboratory evaluation of bone metabolism, plain radiographies of affected bones and bone scintigraphy are sufficient to corroborate the diagnosis. Antiresorptive therapy with bisphosphonates is the mainstay of treatment of symptomatic PDB, and intravenous zoledronic acid has emerged as an effective and safe treatment option, leading to sustained remission and improved quality of life. It is extremely important, though, to ensure calcium and vitamin D sufficiency before and during treatment in order to prevent hypocalcemia. The benefit of treating all asymptomatic patients is not clear, but treatment is warranted if the pagetic lesion is located in a site where progression to fracture, deformity, or compression would significantly impair the patient quality of life. This mini-review focuses on important aspects of the diagnosis and treatment of PDB.

scholarly journals Audit in psychiatry

1989 ◽  
Vol 13 (6) ◽  
pp. 278-281 ◽  
Author(s):  
Gillian Garden ◽  
Femi Oyebode ◽  
Stuart Cumella
Keyword(s):  
Quality Of Life ◽  
Medical Care ◽  
Critical Analysis ◽  
White Paper ◽  
Diagnosis And Treatment ◽  
Medical Audit ◽  
Use Of Resources ◽  
Quality Of Medical Care ◽  
The Government

Medical audit has been defined as the systematic, critical analysis of the quality of medical care, including the procedures used for diagnosis and treatment, the use of resources and the resulting outcome and quality of life for the patient (DOH, 1989). The White Paper Working for Patients states that the Government proposes that every consultant should participate in a form of medical audit agreed between management and the profession locally. It also states that management should be able to initiate an independent professional audit.

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