Staphylococcal and Streptococcal Septic Arthritis in the Elderly

Author(s):  
Don Walter Kannangara ◽  
Don Walter Kannangara ◽  
D. Pandya ◽  
R. Anmolsingh

In our study, septic arthritis due to Staphylococcus aureus and Streptococcal species was more common in the elderly. This contrasts with Lyme arthritis which has a higher incidence in younger patients. The majority of joint infections were in the elderly, with a median age of 65 (range 14-95) for Staphylococcus aureus and 70 for Streptococcal species. The age range of Methicillin-resistant Staphylococcus aureus (MRSA) septic arthritis was 27-95 (median 72) with 39/53 (73.6%) above age 60. The age range of Streptococcal arthritis patients was 36-86 (median 70). There were more males with septic arthritis for both Staphylococcus aureus (86/134) 64% and streptococci (12/22) 55%. The most frequently involved joint was the knee, 49.3% for S. aureus followed by hip (23.9%), elbow (14.3%), shoulder (14%), wrist (1.5%), ankle (0.75%) and sternoclavicular (0.75%). The knee was affected in 81% of Streptococcal infections, with the rest equally divided between the hip, elbow, acromioclavicular and ankle joints. The history of prior joint replacement in patients with septic arthritis was 21/28 (80%) for MRSA, 36/102 (35.3%) for methicillin-susceptible Staphylococcus aureus (MSSA) and 9/21 (43%) for streptococcal arthritis suggestive of healthcare-associated infections. Our results suggest a need for improvements to prevent the entry of pathogens into the surgical site during and after surgery.

2009 ◽  
Vol 27 (2) ◽  
pp. 81-82 ◽  
Author(s):  
Michihiro Ogasawara ◽  
Keisuke Oda ◽  
Ken Yamaji ◽  
Yoshinari Takasaki

We report a case of polyarticular septic arthritis with bilateral psoas abscesses. A 50-year-old woman was admitted with fever, multiple joint swelling and pain. She had a clinical history of acupuncture therapy for treatment of her chronic lower back pain two days before the appearance of her symptoms. Methicillin-sensitive Staphylococcus aureus was isolated from blood culture, knee joint fluids and psoas abscess. After a long course of antibiotics for 70 days together with drainage of the abscess, the condition completely resolved. The acupuncture is the probable cause of the infection, and this case report reveals the importance of asking about a clinical history of acupuncture treatment and of making repeated bacterial examinations in undiagnosed polyarthritis patients.


2020 ◽  
pp. 110-117
Author(s):  
Kylie Greenwald ◽  
Maria Greenwald ◽  
JoAnn Ball

Objectives: To correlate audiometry with atherosclerosis. Presbycusis is associated with age and atherosclerosis; a strong correlation might present opportunities to use audiometry to track atherosclerosis disease. Design: The authors tested 87 elderly patients with rheumatoid arthritis (age range: 80–101 years; median: 86 years) with a history of methotrexate use for over 20 years. After 50 years of age, hearing loss begins slowly and by the age of 90, the majority of the general population require hearing aids. In the 87 elderly participants, however, hearing was remarkably preserved. Results: The observed cohort of 87 individuals showed better hearing than predicted compared to audiometry historically documented in the elderly (p<0.001). The patients tested one to two decades younger than expected on audiometry and 44% of patients qualified for hearing aids instead of the expected 80%, based on age. Conclusion: The known reduction in atherosclerosis with methotrexate use in rheumatoid arthritis may account for this observed preservation of hearing.1,2 As hearing and atherosclerosis are related, the authors further postulated that routine audiometry may provide a cost-effective screening tool for other populations in future atherosclerosis studies.


2020 ◽  
Vol 6 (2) ◽  
pp. 134-143
Author(s):  
Seyyed Mojtaba Tabatabaiasl ◽  
◽  
Parisa Sedaghati ◽  
Fariba Javazi ◽  
◽  
...  

Objective: The purpose of this study was to compare functional balance and probability of fall in elderly with or without history of fall in care centers. Methods: The statistical population of the present study consisted of 30 elderly men and women over 60 years of two elderly nursing centers in rasht. These specimens were selected according to the inclusion criteria and exit criteria. The age range was between 60 and 74 years. Individuals (15 people)were divided into two groups of aged persons (15 persons) and with a history of land (15 people). People who had no history of eating during the last six months have been knocked down in the group without a history of land eating and people who had tripped once or more in the last six months. the evaluation of the balance and the possibility of seniors fall with tests (leaves and time of rise and departure) were carried out. SPSS software was used to analyze the data. from the shayper-vink test to be natural for data distribution, descriptive statistics were used in the form of statistics such as mean, standard deviation, median, change range and direction of data describing and in the deductive statistics section with respect to comparing the variables from independent t-test. Results: Normality test results confirmed normality of data in the variables of performance equilibrium and probability of fall there was a significant difference between functional balance index in the elderly with a history of fall or without the history of fall. there was a meaningful difference between fall risk index in the elderly with a history of fall or without the history of fall. Conclusion: according to the results of this study, individuals with no history of fall in performance balance indices and probability of fall were better than those with history of fall.


2015 ◽  
Vol 40 (3-4) ◽  
pp. 121-128
Author(s):  
Jan Leonard ◽  
Donald Frei ◽  
Kristin Salottolo ◽  
Christopher V. Fanale ◽  
Jeffrey C. Wagner ◽  
...  

Background: Clinical trials confirmed the safety and efficacy of intra-arterial therapy (IAT) in the management of ischemic stroke. At a community hospital, we compared outcomes in patients aged ≥80 and patients in the age range 55-79 years receiving IAT following ischemic stroke. Methods: Data were retrospectively abstracted for ischemic stroke patients ≥55 years treated with IAT at an urban comprehensive stroke center between 2010 and 2013. Baseline demographics, incidence of symptomatic intracranial hemorrhage (sICH), in-hospital mortality, discharge modified Rankin scale (mRS) score (favorable ≤2) and improvement in National Institutes of Health Stroke Scale Score (NIHSS; decreased score at discharge) were compared between patients in the age range 55-79 and patients ≥80 years. Data were analyzed using univariate analyses and multivariate logistic regression. Results: IAT was performed in 239 patients with ischemic stroke; 63 (26.4%) were ≥80 years. When compared to patients aged 55-79, the elderly patients were more often female and non-smokers, with a history of atrial fibrillation. No differences were observed in those ≥80 years compared to patients in the age range 55-79 years for sICH (10 vs. 5%, p = 0.23), mortality (24 vs. 18%, p = 0.28), favorable discharge mRS score (13 vs. 19%, p = 0.27), or improvement in NIHSS (83 vs. 92%, p = 0.10). The nonsignificant association of age with the outcomes persisted after adjusting for covariates and when analyzing the subset of patients who received IAT only. Conclusions: These findings suggest that in a cohort not subject to the criteria of a clinical trial, age ≥80 years should not be a contraindication to IAT.


MedPharmRes ◽  
2018 ◽  
Vol 2 (2) ◽  
pp. 21-31
Author(s):  
Nguyen Phan ◽  
Hien Pham ◽  
Thuc Nguyen ◽  
Hoai Nguyen

Staphylococcus aureus (S. aureus) has long been recognized as an important human pathogen causing many severe diseases. It is also a part of human normal flora with its ecological niche in the human anterior nares. This study focused on screening S. aureus nasal carriage in community and its relationship to human physiological and pathological factors which have not been studied in Vietnam previously. Two hundred and five volunteers in Ho Chi Minh City from 18 to 35 and over 59 years old both male and female participated in the study. Result showed that the prevalence of S. aureus nasal carriage in southern Vietnamese community was relatively low, only 11.2% (23/205), much lower than that in other international reports on human S. aureus. In addition, nasal carriage of the older age group (> 59 years old, 13.7%) was higher than that of younger age (18-35 years old, 10.4%). Other potential risk factors such as gender, career, height, weight, history of antibiotic usage, daily nasal wash, use of nasal medication sprays, acne problems, smoking and nasal problems showed no significant impact on S. aureus carriage. The obtained S. aureus nasal isolates were all sensitive to vancomycin. Lincomycin and tetracycline had low resistance rate with 4.3 % and 17.4 %, respectively. However, the isolates showed particularly high rate of multidrug resistance (54.2%) In summary, our data provided researchers an overview on S. aureus nasal carriage and antibiotic susceptibility profile of the community- isolated S. aureus in Vietnam. This would serve as valuable information on assessing risk of community-acquired S. aureus infections.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S383-S384
Author(s):  
Fatma Hammami ◽  
Makram Koubaa ◽  
Amal Chakroun ◽  
Fatma Smaoui ◽  
Khaoula Rekik ◽  
...  

Abstract Background Malignant otitis externa is a fatal infection of the external ear and temporal bone. Pseudomonas aeruginosa is the most common causative organism, while fungi are a rare cause of malignant otitis externa. We aimed to compare the clinical, therapeutic and evolutionary features between bacterial and fungal malignant otitis externa. Methods We conducted a retrospective study including all patients hospitalized for malignant otitis externa in the infectious diseases department between 2000 and 2018. Results Overall, we encountered 82 cases of malignant otitis externa, among which there were 54 cases (65.9%) of bacterial malignant otitis externa (BMO) and 28 cases (34.1%) of fungal malignant otitis externa (FMO). The males were predominant among BMO cases (57.4% vs 50%; p=0.5). Patients with FMO were significantly older (70±9 years vs 61±10 years; p&lt; 0.001) and had medical history of diabetes mellitus more frequently (96.4% vs 77.8%; p=0.03). The use of topical corticosteroids was significantly more reported among FMO cases (28.6% vs 5.6%; p=0.006). Otalgia (96.4% vs 81.5%), otorrhea (75% vs 66.7%) and cephalalgia (46.4% vs 42.6%) were the revealing symptoms among FMO and BMO, respectively, with no significant difference. Tenderness to palpation of the mastoid bone (64.3% vs 38.9%; p=0.02) and stenosis of the external auditory canal (92.9% vs 72.2%; p=0.02) were significantly more frequent among FMO cases. Complications were significantly more frequent among FMO cases (42.9% vs 9.3%; p&lt; 0.001). Treatment duration was significantly longer among FMO cases (70[40-90] days vs 45[34-75] days; p=0.03). Conclusion Our study showed that FMO affected more frequently the elderly and diabetic patients, when compared with BMO. Regardless of the causative agent, the clinical presentation was similar. However, the outcome was poor among FMO cases with the occurrence of complications, requiring a longer duration of treatment. Disclosures All Authors: No reported disclosures


2021 ◽  
pp. 095646242199719
Author(s):  
Robert Jeffrey Edwards ◽  
Isshad John ◽  
Selena Todd ◽  
Leon-Omari Lavia ◽  
David Musa ◽  
...  

A chart review study was conducted to determine the prevalence of syphilis and explore the associated risk factors among men who have sex with men (MSM) who attended a large HIV clinic in Trinidad during the period January–December 2019. Patients were routinely screened for syphilis annually, and demographic, clinical, and laboratory data were extracted from the medical records. Descriptive and bivariate analyses were performed, and factors significantly associated with a syphilis diagnosis were assessed using multivariate logistic regression. During the period, 218 MSM were seen, age range 19–67 years, and median age 34.0 years. The prevalence of syphilis was 41.3% (90/218), and 71.1% (64//90) of these infections were asymptomatic. Multivariate analysis using logistic regression showed that MSM living with HIV in the 30–34 years old-age group (OR, 4.32; 95% CI, 1.04–18.02), and those with a previous history of treated syphilis (OR, 10.18; 95% CI, 4.60–22.53) were more likely to be diagnosed with syphilis. The prevalence of syphilis is high among MSM attending the HIV clinic in Trinidad, and most of these infections were asymptomatic; hence, targeted and sustained interventions to reduce syphilis transmission are urgently required. Repeat episodes of syphilis may play a role in the transmission dynamics of syphilis in MSM.


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