PREVALENCE OF PERIODONTAL DISEASES IN PATIENTS WITH GOUT
Gout is a systemic disease characterized by an inflammatory reaction at the sites of deposition of sodium monourate crystals in individuals with hyperuricemia and is caused by external factors and (or) genetic factors. Patients with gout often have comorbidities such as cardiovascular disease (including hypertension), diabetes and chronic kidney disease, and dental disease. In the professional literature there are almost no studies of periodontal tissues in patients with gout. The aim of our study was to investigate the prevalence of periodontal disease in patients with gout. The participants were divided into 2 groups: the main one included 150 patients with gout, and the comparative one included 80 people without rheumatic pathology. The age of the subjects ranged from 30 to 50 years or more. The clinical examination was performed according to a standard scheme, which included history taking and analysis of patient’s complaints. According to the results obtained, the patients with gout showed a significantly higher prevalence of periodontal disease in all age groups, compared with individuals with rheumatic pathology. A high percentage of periodontal pathology was observed in the young participants of the main group. The larges share in the structure of periodontal diseases among the patients with gout was represented by advanced generalized periodontitis class I and II, and parodontosis, while the individuals without rheumatic pathology demonstrated a higher percentage of initial stages of periodontal disease. With age, both groups demonstrated the increase in the prevalence of periodontal disease, but in patients with gout, this process was more intense. It can be concluded that systemic disorders associated with gout, among which chronic autoimmune inflammation, oxidative stress, endothelial dysfunction and a high risk of atherosclerosis are very common, can be regarded as predictors of both rapid progression and aggravation of destructive inflammatory lesions of the periodontium.