Phytochemical Composition and Pharmacological Effects of Cassia Fistula

2020 ◽  
Vol 4 (1) ◽  
pp. 59-69
Author(s):  
Muhammad Saeed ◽  
Sumra Naseer ◽  
Shabbir Hussain ◽  
Muhammad Iqbal
Keyword(s):  
Skin Diseases ◽  
Sterculic Acid ◽  
Stem Bark ◽  
Pharmacological Effects ◽  
Cassia Fistula ◽  
Phytochemical Composition ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Cardiac Disorders ◽  
Anti Fungal

Cassia fistula is widely utilized in conventional medicines against various diseases. The plant possesses diverse pharmacological characteristics including anti-tussive, hepatoprotective, anti-pyretic, anti-oxidant, anti-inflammatory, anti-cancer, anti-fungal, anti-microbial, anti-itching, anti-ulcer, anti-epileptic, anti-fertility and wound healing characteristics. Its leaves and bark are used to treat skin diseases,while its roots are useful as diuretic and are used to treat tubercular glands, cardiac disorders, and ulcer. Its fruit pulp is used as a mild laxative in numerous stomach problems. Its flowers are used to treat leprosy, abdominal problems and fever and its seeds possess anti-pyretic, cooling and laxativeproperties. The plant isan important source of tannins, glycosides and flavonoides, linoleic, oleic, stearic and carbohydrates. Its leaves contain glycosides, free rhein, sennosides A and B, isofavoneoxalic acidsandoxyanthraquinones derivatives,while the stem bark contains lepeol, hexacosanol, tannins and B-sitosterol. The pulp is composed of carbohydrate, arginine, protein, leucine and flavonid-3-ol-subordinates. Its pods contain astringent matter, fistulic acids, glutten matter and kaempferol,whereas its seeds are rich in malvalic acid, sterculic acid and vernolic oil. Moreover, aurantimide, ceryl alcohol, kaempferol, anthraquinonees, bianthroquonones and glycosides basic oils are present in the flower.

scholarly journals KEGIATAN FARMAKOLOGIS DARI BERBAGAI BAGIAN Carica papaya Linn. EKSTRAK: BUAH, DAUN, BENIH, UAP, KULIT DAN AKAR

2020 ◽  
Vol 2 (3) ◽  
pp. 211-226
Author(s):  
Tita Kosima Hidayati ◽  
Yasmiwar Susilawati ◽  
Ahmad Muhtadi
Keyword(s):  
Carica Papaya ◽  
Stem Bark ◽  
Phytochemical Content ◽  
Tropical Plant ◽  
Anti Cancer ◽  
Phytochemical Compounds ◽  
Anti Oxidant ◽  
Medicinal Properties ◽  
Anti Fungal ◽  
Phytochemical Contents

Carica papaya (Caricaceae) Linn. (CP) is a popular tropical plant which provide a huge benefit. The fruit is either delicious and healthy while other parts have a great potential medicinal properties. CP are classified as plants that have anti-microbial activity, anti oxidant, anti malaria, anti-ulcer, anti-HIV, anti-inflammatory, anti-cancer, anti-hypertension, anti-fertility, anti-fungal and anti diabetic. Pharmacological activity of papaya plants related to the content of phytochemical  compounds of alkaloid, flavonoid , tannin, saponin, enzyme: papain and chymopapain. These phytochemical  content have been found in the young leaf, stem bark, dry seeds. Papaya leaf reveal more pharmacologycal activities because that have wide variety of phytochemical contents. In this review will be studied pharmacologycal activities  of Carica papaya Linn. extract that  obtained from fruit, leaf, seeds, stem bark and root. Besides, their  various phytochemical contents are also described. 

A review on phyto-pharmacology of Oxalis corniculata

2021 ◽  
Vol 24 ◽  
Author(s):  
Iqra Sarfraz ◽  
Azhar Rasul ◽  
Ghulam Hussain ◽  
Muhammad Ajmal Shah ◽  
Bushra Nageen ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Current Effort ◽  
Isolation And Characterization ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Fungal ◽  
Warm Temperate

: Oxalis corniculata (Oxalidaceae) is a small decumbent and delicate appearing medicinal herb flourishing in warm temperate and tropical domains such as Pakistan and India. Main bioactive chemical constituents of Oxalis plant include several alkaloids, flavonoids, terpenoids, cardiac glycosides, saponins, phlobatannins along with steroids. Due to its polyphenolic, glycosides and flavonoid profile, it is proved to be protective in numerous ailments and exhibit various biological activities such as anti-fungal, anti-cancer, anti-oxidant, anti-bacterial, anti-diabetic, and cardioprotective. Moreover, bioactive phytochemicals from this plant possess significant wound healing potential. Our current effort intends to emphasize on the immense significance of this plant species, which have not been the subject matter of clinical trials and effective pharmacological studies, even though its favored usage has been stated. This review proposes that Oxalis corniculata possess potential for the cure of various diseases, however, further researches on isolation and characterization of bioactive compounds along with pre-clinical trials are compulsory to figure out its pharmacological applications.

Phytochemical and pharmacological aspects of Nothapodytes nimmoniana. An overview

2013 ◽  
Vol 59 (1) ◽  
pp. 53-66 ◽  
Author(s):  
Nazeerullah Khan ◽  
Ennus Tajuddin Tamboli ◽  
V.K. Sharma ◽  
Sunil Kumar
Keyword(s):  
Wide Spectrum ◽  
Pharmacological Activities ◽  
Nothapodytes Nimmoniana ◽  
Jammu And Kashmir ◽  
Medicinal Uses ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Fungal ◽  
Anti Hiv ◽  
Important Medicinal Plant

Summary Nothapodytes nimmoniana (J. Graham) (Icacinaceae), commonly known as Amruta is found in India particularly in Maharashtra, Goa, Kerala, Assam, Jammu and Kashmir as well as Tamilnadu areas. It is an important medicinal plant, the major source of a potent alkaloid, namely camptothecin, of a wide spectrum of pharmacological activities like anti-cancer, anti-HIV, antimalarial, antibacterial, anti-oxidant, anti-inflammatory, anti-fungal and also applied in the treatment of anaemia. Camptothecin is still not synthesized, therefore, its production entirely depends on natural sources. N. nimmoniana is one such plant which yields contain camptothecin in significantly high amount. The plant is gaining international recognition due to its diversified medicinal uses. It is subjected to excessive harvest. It has been categorized as a vulnerable and endangered plant. The present review encompasses the phytochemical, analytical, pharmacological, biotechnological, and other specific aspects of N. nimmoniana.

scholarly journals Biological Activities and Phytochemical Constituents of Trailing Daisy Trilobata: A Review

2019 ◽  
Vol 9 (4-s) ◽  
pp. 888-892
Author(s):  
K Sai Prasanna ◽  
G Jyothi Reddy ◽  
M Kiran ◽  
K Thyaga Raju
Keyword(s):  
Skin Diseases ◽  
Biological Activities ◽  
Pharmacological Activities ◽  
Traditional System ◽  
Wedelia Trilobata ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Anti Inflammatory ◽  
Anti Fungal ◽  
Natural Medicines

The traditional system of medicinal plants have been found to possess significant anti-inflammatory, antibacterial, anti-fungal, anti-diabetic, analgesic properties etc. Plant-derived drugs are used to cure mental illness, skin diseases, tuberculosis, diabetes, jaundice, hypertension, and cancer. Wedelia Trilobata belongs to family Asteraceae. Leaf, stem, and flower of Wedelia trilobata show anti-microbial, anti-oxidant and anti-inflammatory activity, analgesic activity. Phytochemical screening of the extract has been reported to show the presence of tannins, cardiac glycosides, flavonoids, terpenoids, phenols, saponins, and coumarins. Wedelia Trilobata is also used in reproductive problems, amenorrhea, chest cold, dry cough, and fever. The present review aims to the study was phytoconstituents, biological and pharmacological activities of Wedelia trilobata. This study suggested a possible use of Wedelia trilobata as a source of natural medicines as an anti-inflammatory, anti-oxidant, anti-microbial, hepatoprotective, antidiabetic agents. Keywords: Wedelia Trilobata, Trialing daisy trilobata, Complaya trilobata(L), Sphagneticola Trilobata, pharmacological review.

A Review of Various Pharmacological Effects of Quercetin with its Barriers and Approaches for Solubility and Permeability Enhancement

2021 ◽  
Vol 11 ◽  
Author(s):  
Rakesh Mishra ◽  
Shweta Kulkarni
Keyword(s):  
Solid Dispersions ◽  
Aqueous Solubility ◽  
Pharmacological Effects ◽  
Pharmacological Activities ◽  
Human Diet ◽  
Permeability Enhancement ◽  
Current Review ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Novel Approaches

Background: Quercetin, one of the most beneficial flavonoids, has been included in the human diet due to its therapeutic effect on health. Recently, Quercetin is gaining scientific attraction for its multifarious activities, including anti-oxidant, anti-inflammatory, antiviral, anti-diabetic, anti-cancer, anti-arthritic, as well as function to ease some cardiovascular diseases. However, these applications of quercetin in the pharmaceutical field are limited due to its poor aqueous solubility and poor permeability. Objective: The present review summarizes various pharmacological activities of quercetin, analyses the barriers like solubility and permeability, which restrict the therapeutic efficiency of quercetin, and also discusses novel approaches to enhance aqueous solubility and permeability of quercetin for its effective clinical use. Methods: The current review information sources were peer-reviewed relevant scientific articles of recognized journals from scientific engines and databases (Scopus, Web of Science, PubMed, Science Direct, Google Scholar) using different key words related to quercetin pharmacological effects, mechanism, solubility, permeability, absorption barriers, and formulation approaches. Results: Various novel approaches, including solid dispersions, inclusion complex, pro-drugs, nanoemulsion, micelles, liposomes, SNEEDS, and microspheres, have been developed to overcome the solubility and permeability barriers for efficient quercetin delivery. Conclusion: This review revealed that the multifaceted pharmacological activities of quercetin for management of various disease are enormously dependent on the development of novel and safe drug delivery systems of quercetin.

scholarly journals Pistacia integerrima (Shringi)- A Plant with Significant Pharmacological Activities

2021 ◽  
Vol 10 (5) ◽  
pp. 323-330
Author(s):  
Manish Grover ◽  
Keyword(s):  
Skin Diseases ◽  
Pharmacological Activities ◽  
North West ◽  
Alpha Pinene ◽  
Anti Cancer ◽  
The Family ◽  
The World ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Important Medicinal Plant

Pistacia integerrima is an important medicinal plant belongs to the family Anacardiacea. It is commonly called as Crab’s claw in English and Shani/Shringi in Hindi. It is a single-stemmed, dioecious tree widely distributed in countries like Nepal, China, Afghanistan, Pakistan, Armenia, North-west and West Himalayas. The plant has significant applications in the traditional systems of medications such as Ayurveda, Unani and Siddha. In addition, the plant is also used in many folkloric cultures around the world to treat a vast array of human ailments such as diarrhoea, dysentery, fever, vomiting, skin diseases, respiratory ailments and psoriasis appetizer, hepatitis and liver related disorders. The characteristic feature of the plant is its essential oil content comprised of many important phytochemical constituents such as alpha-pinene, camphene, di-limonene, 1:8-cineol, caprylic acid, alpha-terpineol and aromadendrene. However, the plant contains many other important secondary metabolites such as steroids, flavonoids, tannins, saponins and phenols which are associated with important pharmacological activities such as anti-bacterial, anti-oxidant, anti-inflammatory, cardio-protective, anti-cancer, antidiarrhoeal, anticonvulsant and muscle relaxant. The aim of the present study is to summarize the recent pharmacological activities of Pistacia integerrima along with its utilization in traditional medication systems

scholarly journals Pharmacognostical standardization, formulation and evaluation of tablets incorporated with stem bark of Butea monosperma for anti cancer activity

2019 ◽  
Vol 9 (1) ◽  
pp. 114-123
Author(s):  
Pragada Venkateswara Rao ◽  
Bura Nagaraju ◽  
Pajjuri Venkanna ◽  
Vasudha Bakshi ◽  
Narender Boggula
Keyword(s):  
Methanolic Extract ◽  
Stem Bark ◽  
Compression Method ◽  
Butea Monosperma ◽  
Anti Cancer ◽  
Hepg2 Cell Lines ◽  
Anti Fungal ◽  
Eac Cells ◽  
Cancer Activity ◽  
Pvp K30

The plant Butea monosperma (Palas) popularly known as 'dhak' or 'palas' and commonly known as ‘Flame of forest’ belongs to family Fabaceae. This herb is indigenous to India. The plant is traditionally reported to possess astringent, bitter, alterative, aphrodisiac, anthelmintic, antibacterial and anti-asthmatic, anthelmintic, anti-conceptive, anti-convulsive, anti-diabetic, anti-diarrhoeal, anti-estrogenic, anti-fertility, anti-microbial, anti-fungal, anti-bacterial, anti-stress, chemopreventive, hepatoprotective. The present research investigation was envisaged on pharmacognostical standardization, formulation and evaluation of tablets incorporated with methanolic extract of stem bark Butea monosperma for anti cancer activity. Conventional release tablets of methanolic extract of Butea monosperma stem bark (MEBMSB) were formulated using Microcrystalline Cellulose as a filler and PVP-k30 as a binder by direct compression method. Finally from this research investigation it can be concluded that methanolic extract of Butea monosperma stem bark has moderate anti-cancer activity when compare to standards and be suggested as a better substitute for the synthetic anti cancer drugs. Keywords: Butea monosperma, anti cancer activity, MTT assay, EAC cells, DAC cells, HepG2 cell lines.

scholarly journals Flavonoids: isolation, characterization, and health benefits

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Abiche Ekalu ◽  
James Dama Habila
Keyword(s):  
Secondary Metabolites ◽  
Health Benefits ◽  
The Body ◽  
Pharmacological Activities ◽  
Potential Health ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Plant Families ◽  
Anti Fungal

Abstract Background The unique and vast pharmacological activities of flavonoids have made them of research interest. This led to the use of various techniques to isolate and characterize them, intending to determine their potential health benefits. Main text The medicinal values of plant-based flavonoids that this literature review tends to summarize the pharmacological activities of these secondary metabolites from 22 selected plant families. The pharmacological shreds of evidence reported in the literature have proven that flavonoids have shown anti-cancer, anti-microbial, anti-oxidant, anti-inflammatory, anti-fungal, anti-ulcer, and anti-edematogenic activities. Out of these, 30% showed to have anti-oxidant activity, key in protecting the body against free radicals. Besides, 18% of the references showed anti-microbial and anti-cancer activities. Further literature reports indicated that flavonoids from these families exhibited anti-inflammatory and anti-edematogenic (9%), anti-viral and anti-ulcer (5%), anti-fungal, anti-nociceptive, and anti-histamine (2%). Conclusion The pharmacological activities of flavonoids from the various sources reviewed in this study show that the secondary metabolites could provide a scaffold for the development of potent anti-cancer drugs in the future.

Role of Rasayan Churna in outbreak of Covid -19 as preventive and curative aspect

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1208-1212
Author(s):  
Amol Madhav Deshpande ◽  
Mayuri Amol Deshpande
Keyword(s):  
Recurrent Infection ◽  
Symptomatic Patient ◽  
H1n1 Influenza ◽  
Drug Of Choice ◽  
Asymptomatic Patients ◽  
Diseased Person ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Immune Booster ◽  
Respiratory Droplets

In last two decade world suffer with three epidemic diseases like SARS-CoV, H1N1 influenza, MERS –CoV and presently the world under a pandemic of Covid-19, out of these SARS-CoV, MERS –CoV and Covid-19 are form the same virus call as corona, which primary present on bats and transferred from animal to human, and then it transfer from human to human mostly by respiratory droplets or in the direct contact with the diseased person, these recurrent infection of corona virus is the burning issue in the word, so to avoid these recurrent infections good habitual behaviour with regular immune booster medicine should be taken which can be used in both normal and symptomatic patient for this Rasayan churna  is the best drug of choice as it is used for  rejuvenation therapy. From literally study from various recourses it is found that Rasayan churna have property anti-depressant, anti-xylotic, Immunomodulatory, Anti-diabetes, anti hypertensive, anti-inflammatory, Anti-toxic effects, Anti-arthritic, Anti-cancer effects, Anti-microbial effect, and Anti-oxidant which can be useful in preventive aspect of Covid -19 in all phase like normal individual, also can be used in asymptomatic patients and symptomatic patients, clinical study can be performed for the same to evaluate the result.

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