scholarly journals Overview of the ukrainian pharmaceuitical market of medications for periodontal diseases treatment in order to obtain a new dental product

2020 ◽  
pp. 4-11
Author(s):  
I. Y. Borisyuk ◽  
L. M. Unhurian ◽  
N. S. Fizor ◽  
O. I. Bielyaieva ◽  
А. V. Zamkovaya
Keyword(s):  
Classification System ◽  
Periodontal Diseases ◽  
Pharmaceutical Market ◽  
The Body ◽  
Raw Material ◽  
Material Base ◽  
Ministry Of Health ◽  
Prophylactic Measures ◽  
Trade Names ◽  
Topical Medications

Oral diseases occupy the leading position among common disorders. The etiological factors of the inflammatory processes of the oral cavity can be some general disturbances of the body. Today, the topical medications are important component of the treatment and prophylactic measures of range of pathological conditions in dental practice. Among this type of medicines widely used herbal preparations, which are known for their broad spectrum of activity. The aim of the research was to scrutiny the treatment methods for OD, to study the topical medications assortment of the pharmaceutical market of used in pharmacotherapy of OD with a view to further developing the dosage form and determining the feasibility of its use in the apitherapy of OD and the possibility of occupying it with certain market niche. The data from official information sources, in particular, the List of registered drugs approved for use in Ukraine as of 01. 01. 2019 were used as the objects of study. Market analysis was carried out using the ATC classification system (Anatomical Therapeutic Chemical) taking into consideration international non-patented and trade names, dosage forms, country of manufacture. Statistical, graphic, logical and marketing studies were conducted during the work. Information was used to determine the assortment of the modern pharmaceutical market of drugs that can be used in pharmacotherapy of OD, was the order of the Ministry of Health of Ukraine No. 566 dated 11. 23. 2004. «On approval of protocols for the provision of medical care in the fields of "orthopedic dentistry", "therapeutic dentistry", "surgical dentistry", "orthodontics", "pediatric therapeutic dentistry" and "pediatric surgical dentistry"». According to the official website of the SEC of the Ministry of Health of Ukraine as of 01. 01. 2019, 76 drugs were registered as the A01A group and 59 drugs under trade names. According to the АТС classification system major topical medications belong to group A01A. The share of domestic drugs prevails over foreign ones and amounts to 60.5%. Attention was drawn to the limited range of drugs from beekeeping products, whose share is only 6.6%. It has been found that the production of original propolis-based drugs at pharmaceutical enterprises of Ukraine with a sufficient raw material base is topical issue of pharmacy.

scholarly journals The analysis of prolonged-release drugs at the Ukrainian pharmaceutical market

2021 ◽  
Vol 7 (3) ◽  
pp. 64-72
Author(s):  
K. V. Tarapon ◽  
O. V. Tryhubchak
Keyword(s):  
Nervous System ◽  
Classification System ◽  
Marketing Research ◽  
Dosage Forms ◽  
Pharmaceutical Market ◽  
Prolonged Release ◽  
Scientific Analysis ◽  
Inflammatory Drugs ◽  
Trade Names ◽  
Marketing Methods

Aim. To analyze the range of prolonged-release dosage forms at the Ukrainian pharmaceutical market focusing on the pharmacotherapeutic groups that are insufficiently saturated with prolonged-release drugs, in particular to determine the proportion of non-steroidal anti-inflammatory drugs (NSAIDs). Materials and methods. The research was conducted in accordance with the data of the State Registry of Medicines of Ukraine and the АТС classification system. The methods of scientific analysis, in particular methods of grouping and comparison, marketing methods of analysis were applied. Results. The study of the assortment of prolonged-release drugs registered at the Ukrainian pharmaceutical market has been performed. The structure of the assortment by manufacturer, dosage forms, the АТС classification system has been analyzed. As a result of the study, it has been found that 202 trade names of prolonged-release drugs are registered in Ukraine. Most of them (196 names, 84 %) are medicines of foreign manufacturers. Prolonged-release drugs registered in Ukraine are mostly presented in the form of tablets and capsules, but tablets (72.77 %) are the largest part. The analysis of distribution of prolonged-release drugs by the ATC classification groups has shown that a significant number of prolonged-release drugs belongs to group N – Nervous system (80 trade names), and group C – Cardiovascular system (44 trade names). The share of group M – Musculoskeletal system, in particular prolonged-release NSAIDs, is insignificant (9 trade names). Conclusions. The marketing research of the prolonged-release drugs conducted allowed us to characterize the structure of the assortment of the Ukrainian market by pharmacotherapeutic groups, manufacturers and dosage forms. As a result of the research, the current assortment of prolonged-release NSAIDs has been determined.

scholarly journals EFFECTIVENESS OF LOCAL TREATMENT OF INFLAMMATORY PERIODONTAL DISEASES IN WOMEN WITH PREGNANCY COMPLICATED BY HESTOSIS

2019 ◽  
Vol 15 (3) ◽  
pp. 69-74
Author(s):  
Сергей Чуйкин ◽  
Sergey Chuykin ◽  
Гузель Акмалова ◽  
Guzel' Akmalova ◽  
Елена Егорова ◽  
...  
Keyword(s):  
Oral Fluid ◽  
Periodontal Diseases ◽  
Local Treatment ◽  
The Body ◽  
Dental Status ◽  
Local Immunity ◽  
Significant Group ◽  
Prophylactic Measures ◽  
Complicated Pregnancy ◽  
Chamomile Flowers

For a woman’s dental health, pregnancy is a critical period, characterized by an exacerbation of inflammatory periodontal diseases before pregnancy, as well as a significant increase in dental caries. Using a significant group of drugs during pregnancy is not safe for a woman's body. In this regard, in the treatment of periodontal diseases, the inclusion of phytopreparations into the complex of treatment and prophylactic measures that can restore local immunity, reduce inflammation and accelerate the restoration of the mucous membrane, which have minimal side effects on the body as a whole, is of great importance. The aim of the work was to assess the clinical effectiveness of the local use of a new chewing phytosubstrate containing beeswax and dry aqueous boron extract, consisting of oak bark, alder fruit, birch buds, chamomile flowers and thyme grass in women with gingivitis with gestosis complicated pregnancy. Methods. A survey was conducted of 127 pregnant women, of which 79 pregnant with gestosis and 48 patients with a physiological course of pregnancy at the age of 18-34 years in the II and III trimesters. Results. The dental status and physicochemical properties of the oral fluid in women with gestational complications of pregnancy were studied before and after the application of the new phytosubstrate. Conclusions. The chewing substrate containing beeswax and dry aqueous extract consisting of oak bark, alder fruit, birch buds, chamomile flowers and thyme herbs has been found to be highly effective in the prevention and treatment of gingivitis in women with gestosis complicated pregnancy, which was confirmed by improved biochemical and physico-chemical indicators of oral fluid, as well as clinical indicators of dental status. in women with gestational complications.

The interasin raw material base of coke-chemical production of Ukraine: Problems of charge formation, its preparation and coking

2018 ◽  
Vol 5 (6) ◽  
pp. 3-7 ◽  
Author(s):  
E.S. Popov ◽  
V.I. Gavrilyuk ◽  
N.V. Mukina ◽  
E.T. Kovalev ◽  
I.D. Drozdnik ◽  
...  
Keyword(s):  
Raw Material ◽  
Material Base ◽  
Chemical Production ◽  
Charge Formation

Anthocyanins: Chemical Properties and Health Benefits: A Review

2021 ◽  
Vol 17 ◽  
Author(s):  
Siraj Salman Mohammad ◽  
Renata Oliveira Santos ◽  
Maria Ivone Barbosa ◽  
José Lucena Barbosa Junior
Keyword(s):  
Raw Materials ◽  
Health Benefits ◽  
Chemical Properties ◽  
Extraction Methods ◽  
The Body ◽  
Raw Material ◽  
Extraction Properties ◽  
Therapeutic Properties ◽  
Food Processes ◽  
Shed Light

: Anthocyanins are widely spread in different kinds of food, especially fruits and floral tissues, there is an extensive range of anthocyanin compounds reach more than 600 exist in nature. Anthocyanins can be used as antioxidants and raw material for several applications in food and pharmaceutical industry. Consequently, a plenty of studies about anthocyanins sources and extraction methods were reported. Furthermore, many studies about their stability, bioactive and therapeutic properties have been done. According to the body of work, we firstly worked to shed light on anthocyanin properties including chemical, antioxidant and extraction properties. Secondly, we reported the applications and health benefits of anthocyanin including the applications in food processes and anthocyanin characteristics as therapeutic and prophylactic compounds. We reviewed anticancer, anti-diabetic, anti-fatness, oxidative Stress and lipid decreasing and vasoprotective effects of anthocyanins. In conclusion, because the importance of phytochemicals and bioactive compounds the research is still continuing to find new anthocyanins from natural sources and invest them as raw materials in the pharmaceutical and nutrition applications.

scholarly journals COVID-19 and Alcohol Poisoning: A Fatal Competition

2021 ◽  
pp. 1-10
Author(s):  
Mohammad Heidari ◽  
Nasrin Sayfouri
Keyword(s):  
Side Effects ◽  
Alcohol Consumption ◽  
Mass Media ◽  
The Body ◽  
Ministry Of Health ◽  
Alcohol Poisoning ◽  
Methanol Poisoning ◽  
The Public

ABSTRACT In March 2020, concurrently with the outbreak of COVID-19 in Iran, the rate of alcohol poisoning was unexpectedly increased in the country. This study has attempted to make an overall description and analysis of this phenomenon by collecting credible data from the field, news, and reports published by the emergency centers and the Iranian Ministry of Health. The investigations showed that in May 20, 2020, more than 6150 people have been affected by methanol poisoning from whom 804 deaths have been reported. A major cause of the increased rate of alcohol poisoning in this period was actually the illusion that alcohol could eliminate the Coronaviruses having entered the body. It is of utmost importance that all mass media try to dismiss the cultural, religious, and political considerations and prepare convincing programs to openly discuss the side-effects of forged alcohol consumption with the public, especially with the youth. It must be clearly specified that “consuming alcohol cannot help prevent COVID-19.”

Research on the Recovery of Copper from Metallurgical Slag

Mining Revue ◽  
2021 ◽  
Vol 27 (3) ◽  
pp. 40-44
Author(s):  
Eugen Traistă ◽  
Camelia Bădulescu ◽  
Maria Lazăr ◽  
Camelia Traistă
Keyword(s):  
Metallurgical Slag ◽  
Industrial Wastes ◽  
Raw Material ◽  
Pollutant Emissions ◽  
Material Base ◽  
Metallurgical Slags ◽  
Slag Processing ◽  
Metallurgical Processes ◽  
Initial Research ◽  
Over Time

Abstract Metallurgical slag is one of the most common industrial wastes. Many of these wastes are not stable over time, by reacting with water and air, continuously generating emissions of heavy metals. Metallurgical slag processing is necessary for at least two reasons: reducing pollutant emissions and broadening the raw material base. The recovery of these slags is very difficult because they are the result of metallurgical processes that aimed to fix metals considered impurities in chemical matrices as stable as possible. This paper presents the initial research on the behavior of metallurgical slags against different leaching technologies.

Adjustment of a technology of cast iron smelting in the blast furnace of jsc "ural steel" w ith a volume of 1232 см3 with charge h a v in g 95% share of Mikhailovskii GOK pellets

2021 ◽  
Vol 77 (7) ◽  
pp. 768-775
Author(s):  
I. F. Iskakov ◽  
G. A. Kunitsyn ◽  
D. V. Lazarev ◽  
А. А. Red`kin ◽  
S. A. Trubitsyn ◽  
...  
Keyword(s):  
Blast Furnace ◽  
Iron Ore ◽  
Raw Materials ◽  
Raw Material ◽  
Material Base ◽  
Hot Metal ◽  
Charging System ◽  
Iron Smelting ◽  
Gas Consumption ◽  
A Charge

To use effectively internal raw material base, JSC “Ural Steel” accomplished I category major overhaul of the blast furnace No. 2. The main purpose of the overhaul was to design a rational profile which could ensure an ability to operate with a charge containing 95 % of Mikhailovskii GOK (mining and concentrating plant) pellets having basicity of 0.5 by CaO/SiO2. The blast furnace No. 2 having useful volume of 1232 m3, was constructed by design of Danieli Corus, the Netherlands, and was blown in on December 30, 2020. In the process of guarantee tests, step-by-step increase of Mikhailovskii GOK pellets (Fetotal = 60.5 %, CaO/SiO2 = 0.5) content in the charge iron ore part was being accomplished from 55 to 95.1%. Charging of the blend containing pellets in the amount of 55% of iron ore part, was done by charging system 4OOCC + 1COOCC (Ore - Coke) with filling level 1.5 m. Under conditions of pellets part increase in the blend, the charging system was changed to decrease their content at the periphery, to increase it in the ore ridge zone and make it intermediate between periphery and the ore ridge. At the pellets share in the iron ore raw materials 0.75 the charging system was used as the following: 3OOCC + 1COOC + 1COOCC, while at the content 95.1% the following charging system was used: 2COOC + 2COOC + 1COOCC. It was noted that in the period of guarantee tests the furnace running was smooth. The average silicon content in the hot metal was 0.70% at the standard deviation 0.666. Sulfur content in the hot metal did not exceed 0.024%, the blowing and natural gas consumption figures were 2100 m3/min and 11000 m3/min correspondently, oxygen content in the blowing 26.5%, hot blowing and top smoke pressure figures were 226.5 and 109.8 KPa correspondently. The productivity of the furnace was reached as high as 2358 t/day at the specific coke rate 433 kg/t of hot metal. After guarantee tests completion, the pellets content in the iron ore part was decreased gradually from 95 down to 50%. The decreasing was made by 5% in every 6 hours of operation. Application of the mastered technology of the blast furnace No. 2 with the increased share of pellets will enable to stably supply the blast furnaces No. 1, 3 and 4 by iron ore raw materials in the proportion of 30-35% of pellets and 65-70% of sinter.

Studying the Effect of some Factors on the Stress-Strain Behavior of the Rostov Region Limestones in the Course of their Production and Use

2021 ◽  
Vol 1022 ◽  
pp. 80-86
Author(s):  
Mikhail G. Kholodnyak ◽  
Sergey A. Stelmakh ◽  
Evgeniy M. Shcherban ◽  
Mukhuma P. Nazhuev
Keyword(s):  
Construction Material ◽  
Experimental Studies ◽  
Raw Material ◽  
Material Base ◽  
Strain Behavior ◽  
Current State ◽  
Rostov Region ◽  
Literary Sources ◽  
Crushed Granite ◽  
Strain Stress

The paper considers the current state of the mineral raw material base and the construction material market of the Rostov Region. The effect of various factors on the strain-stress behavior of local limestones has been investigated. The scientific and technical literary sources devoted to the processes of rock failure under various loads have been analyzed. The experimental studies have shown that the tested samples of limestone with a high content of cuboidal grains have characteristics comparable to those of the crushed granite stone. It has been concluded that the use of the Rostov Region limestones in the construction industry is competitive and feasible, provided the proper implementation of the engineering measures proposed in their production.

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