Risk Factors of Congenital Anomalies in South Sumatera Indonesia

Abstract Introduction. Congenital anomaly is one of the leading causes of neonatal death. It is the third leading cause of neonatal death in Indonesia. More than half of all congenital anomalies can’t be related to a specific cause, suggesting multiple risk factors. This study aims to identify patterns and risk factors of congenital anomalies in RSUP Dr. Mohammad Hoesin Palembang. Methods. This observational descriptive study with a cross-sectional design used 100 patients’ medical records, taken at RSUP Dr. Mohammad Hoesin Palembang, as samples. Missing data were complemented with a phone interview. Samples were picked using a proportional random sampling method. Collected data were counted within each category of congenital anomalies. Results. There were 366 neonatal patients diagnosed with congenital anomalies at RSUP Dr. Mohammad Hoesin Palembang in 2015. The most prevalent (44,8%) congenital anomalies belonged to congenital anomalies of the digestive system, followed by congenital anomalies of the circulatory system (18,6%), and cleft lip/palate (11,5%). Following risk factors were found: the history of maternal active or passive smoking (41%), maternal exposure to chemicals or solvents (31%), family member with congenital anomalies of the same category (27%), maternal drug consumption (26%), maternal infection (22%), maternal diabetes mellitus (4%), and maternal hypertension (4%). Conclusion. History of maternal active or passive smoking was the most frequently found risk factors among patients of congenital anomalies.

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Incidence of Orofacial Clefts in Kumasi, Ghana

ISRN Plastic Surgery ◽

10.5402/2013/280903 ◽

2013 ◽

Vol 2013 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

P. Agbenorku ◽

M. Yore ◽

K. A. Danso ◽

C. Turpin

Keyword(s):

Cleft Palate ◽

Congenital Anomalies ◽

Cleft Lip ◽

Cleft Lip And Palate ◽

Orofacial Clefts ◽

Female Ratio ◽

Live Births ◽

Male Female Ratio ◽

Cleft Lip Palate ◽

History Of

Background. Cleft lip and cleft palate are among the most common orofacial congenital anomalies. This study is to establish Orofacial Clefts Database for Kumasi, Ghana, with a view to extend it to other cities in future to obtain a national orofacial anomaly database. Methods. A descriptive prospective survey was carried out at eleven selected health facilities in Kumasi. Results. The total number of live births recorded was 27,449. Orofacial anomalies recorded were 36, giving an incidence of 1.31/1000 live births or 1 in 763 live births. The mean maternal age of cleft lip/palate babies was 29.85 years (range 18–40 years). The male : female ratio for the orofacial anomalies babies was 1.3 : 1; the male : female ratio was 0.5 : 1 in the cleft lip group, 1.3 : 1 in the cleft lip and palate group, and 4 : 1 in the cleft palate group. The majority of clefts were unilateral (69.4%, n=25), with females (n=14) outnumbering males (n=11). A family history of cleft was recorded with five babies (13.9%). Associated congenital anomalies were recorded in seven (19.4%) cleft lips and/or palates. Conclusion. The incidence of 1 in 763 live births found in this study indicates that cleft lip/palate is a common congenital anomaly in Kumasi.

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Study of Cleft Lip and Palate in Kathmandu Model Hospital, Nepal

Orthodontic Journal of Nepal ◽

10.3126/ojn.v9i1.25682 ◽

2019 ◽

Vol 9 (1) ◽

pp. 6-10

Author(s):

Sanzida Khatun

Keyword(s):

Cleft Palate ◽

Congenital Anomalies ◽

Cleft Lip ◽

Cleft Lip And Palate ◽

Positive Family History ◽

First Trimester ◽

Associated Anomalies ◽

Cross Sectional ◽

History Of ◽

First Trimester Of Pregnancy

Introduction: Cleft lip and/or palate is a congenitally persistent space affecting orofacial region. It is generally divided into cleft lip (CL), cleft palate (CP) and cleft lip with cleft palate (CLP). The objective of the study was to evaluate distribution of patterns of orofacial clefts according to sex and laterality; predisposing factors and other congenital anomalies associated with cleft lip and/or palate. Materials & Method: A cross-sectional descriptive type of study was carried out using in 268 patients having cleft lip and/or palate. Types of clefts, predominance of sex and laterality, familial history, associated anomalies and drug and disease history of mother were recorded. Result: The results revealed 23.51% CL, 54.85% CLP and 21.64% CP. There were 58.21% males and 41.79% females. Positive family history of cleft was present in 28.0% and associated anomalies were observed in 3.7% of the cleft subjects. Mothers of 6.0% of the total patients were exposed to teratogenic agents during first trimester of pregnancy. Conclusion: It was concluded that among the three types of cleft (CL, CP and CLP), CLP is the most common type. The males are affected more with cleft lip and/or palate than the females. Clefts also have risks of associated congenital anomalies. Exposure to teratogenic agents in first trimester of pregnancy is also associated with orofacial cleft.

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Demographic Factors Associated with Congenital Malformations Among Young Infants in Fallujah Maternity and Children Hospital, Fallujah City, Iraq

10.31487/j.gg.2020.01.03 ◽

2020 ◽

pp. 1-5

Author(s):

Samira T.Abdulghani ◽

Samira T.Abdulghani

Keyword(s):

Developing Countries ◽

Congenital Anomalies ◽

Prevalence Rate ◽

Gestational Hypertension ◽

Heart Defects ◽

Demographic Factors ◽

Cross Sectional ◽

Factors Associated ◽

Young Infants ◽

History Of

Background: Congenital anomalies are a major cause of infant morbidity and mortality in developing countries including our country. Registries and data on these anomalies are still primitive and poorly collated. In this study we aimed to assess the important demographic factors associated with the development of congenital anomalies. Methods: This was a cross-sectional hospital-based study involving 880 infants in the 1st year of life registered in the birth defect unit in Fallujah Maternity and Children Hospital in the period between 1st of January 2017 to the 31st of December 2019. The prevalence rate, the pattern of anomalies and the factors associated with their occurrence were determined. Results: The prevalence rate of the group enrolled in this study was 31/1000 total births, congenital heart defects was the commonest followed by central nervous system anomalies, 58% of the infants were males, 65% had ≥ 2.5 kg birth weight & 95% were singletons. Family history of congenital anomalies was found in 31.25% of cases. The largest group of mothers (55.7%) were 21-30 years old & 92.5% of fathers were less than 45 years old. Parental consanguinity reported in 64.3% of the total cases. Only 4.5% of mothers reported history of fever during pregnancy, and none of them had history of exposure to x-ray or teratogenic drug use. Gestational hypertension was reported in 10% of the total (880) mothers, hypertension and diabetes mellitus in 0.3%, while hepatitis C, hepatitis B, toxoplasmosis and epilepsy, each was reported in only one mother (0.1% of the total). Regarding the outcome of pregnancy, 66.6% were live births, 24.2% were abortions and 9.2% were stillbirths. History of previous abortions was reported in 22% of cases. Urban residents accounted for 63% of the families of congenitally abnormal infants while 37% were rural. Conclusion: Congenital anomalies are still a major cause for concern and tension in Fallujah society, there is serious need to establish a surveillance and good statistical system for congenital anomalies and efforts should be made to raise awareness of their occurrence and the associated risk factors in Iraq and other developing countries.

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Prevalence of bone fracture and its association with severe hypoglycemia in Japanese patients with type 1 diabetes

BMJ Open Diabetes Research & Care ◽

10.1136/bmjdrc-2020-002099 ◽

2021 ◽

Vol 9 (1) ◽

pp. e002099

Author(s):

Yuji Komorita ◽

Masae Minami ◽

Yasutaka Maeda ◽

Rie Yoshioka ◽

Toshiaki Ohkuma ◽

...

Keyword(s):

Risk Factors ◽

Type 1 Diabetes ◽

Fracture Risk ◽

Bone Fracture ◽

Severe Hypoglycemia ◽

Japanese Patients ◽

Anatomic Site ◽

Cross Sectional ◽

History Of

IntroductionType 1 diabetes (T1D) is associated with higher fracture risk. However, few studies have investigated the relationship between severe hypoglycemia and fracture risk in patients with T1D, and the results are controversial. Besides, none has investigated the risk factors for fracture in Asian patients with T1D. The aim of the present study was to investigate the prevalence of bone fracture and its relationship between severe hypoglycemia and other risk factors in Japanese patients with T1D.Research design and methodsThe single-center cross-sectional study enrolled 388 Japanese patients with T1D (mean age, 45.2 years; women, 60.4%; mean duration of diabetes, 16.6 years) between October 2019 and April 2020. The occurrence and circumstances of any fracture after the diagnosis of T1D were identified using a self-administered questionnaire. The main outcomes were any anatomic site of fracture and fall-related fracture. Severe hypoglycemia was defined as an episode of hypoglycemia that required the assistance of others to achieve recovery.ResultsA total of 92 fractures occurred in 64 patients, and 59 fractures (64%) were fall-related. Only one participant experienced fracture within the 10 years following their diagnosis of diabetes. In logistic regression analysis, the multivariate-adjusted ORs (95% CIs) of a history of severe hypoglycemia were 2.11 (1.11 to 4.09) for any fracture and 1.91 (0.93 to 4.02) for fall-related fracture. Fourteen of 18 participants with multiple episodes of any type of fracture had a history of severe hypoglycemia (p<0.001 vs no fracture).ConclusionsWe have shown that a history of severe hypoglycemia is significantly associated with a higher risk of bone fracture in Japanese patients with T1D.

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Analysis of Sociodemographic and Clinical Factors Associated with Hospitalized Stroke Patients of Bangladesh

Faridpur Medical College Journal ◽

10.3329/fmcj.v6i1.7405 ◽

1970 ◽

Vol 6 (1) ◽

pp. 19-23 ◽

Cited By ~ 6

Author(s):

AM Hossain ◽

NU Ahmed ◽

M Rahman ◽

MR Islam ◽

G Sadhya ◽

...

Keyword(s):

Risk Factors ◽

Heart Disease ◽

Ischaemic Heart Disease ◽

Low Income ◽

Heart Diseases ◽

Previous History ◽

Stroke Patients ◽

College Hospital ◽

Cross Sectional ◽

History Of

A hospital based cross sectional study was carried out to analyze prevalence of risk factors for stroke in hospitalized patient in a medical college hospital. 100 patients were chosen using purposive sampling technique. Highest incidence of stroke was between the 6th and 7th decade. Patients came from both urban (54%) and rural (46%) areas and most of them belong to the low-income group (47%). In occupational category; service holder (28%) and retired person (21%) were the highest groups. Most of the study subjects were literate (63%). CT scan study revealed that the incidence of ischaemic stroke was 61% and haemorrhagic stroke 39%. Analysis indicated hypertension as major risk factor for stroke (63%) and major portion of the patients (42.85%) were on irregular or no treatment. Twenty four percent of the patients had heart diseases and out of 24 patients 45.83% were suffering from ischaemic heart disease. The present study detected diabetes in 21% patients. Fifty three percent of the study subjects were smoker, 39% patients had habit of betelnut chewing. Out of 26 female patients, only 23% had history of using oral contraceptives. Majority of the patients were sedentary workers (46%). Thirty seven percent of the stroke patients were obese. Among the stroke patients 9% had previous history of stroke and 3% had TIA respectively. Most of the patients (21%) were awake while they suffered from stroke and the time of occurrence was mostly in the afternoon (46%). This study found that hypertension, cigarette smoking, ischaemic heart disease and diabetes mellitus are the major risk factors prevalent in our community while other risk factors demand further study. Key words: stroke; risk factors; hospitalized patients; Bangladesh. DOI: 10.3329/fmcj.v6i1.7405 Faridpur Med. Coll. J. 2011;6(1): 19-23

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The Cross-Sectional Determinants of Secessionism in Advanced Democracies

Comparative Political Studies ◽

10.1177/0010414004272538 ◽

2005 ◽

Vol 38 (3) ◽

pp. 304-326 ◽

Cited By ~ 72

Author(s):

Jason Sorens

Keyword(s):

Risk Factors ◽

Regression Analysis ◽

Ethnic Identity ◽

Ethnic Conflict ◽

Political System ◽

Regional Level ◽

Cross Sectional ◽

Regional Language ◽

History Of ◽

Advanced Democracies

This article analyzes the “risk factors” of secessionism at the substate, regional level. It seeks to answer the question, What regions are more likely to support more successful secessionist parties? Using new data in cross-sectional regression analysis, the author finds that secessionism involves unique factors not common to other kinds of ethnic conflict. Specifically, in addition to “identity” variables such as regional language and history of independence, the following variables explain secessionist strength: lack of irredentist potential, relative affluence, geographical noncontiguity, population, and multiparty political system. These factors generally serve as activators of ethnic identity rather than a substitute for the same, although there are important cases of nonethnic secessionism.

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The prevalence and risk factors of musculoskeletal disorders among subcontracted hospital cleaners in Thailand

Journal of Health Research ◽

10.1108/jhr-01-2021-0040 ◽

2021 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Thanaphum Laithaisong ◽

Wichai Aekplakorn ◽

Paibul Suriyawongpaisal ◽

Chanunporn Tupthai ◽

Chathaya Wongrathanandha

Keyword(s):

Risk Factors ◽

Musculoskeletal Disorders ◽

Teaching Hospital ◽

Stress Test ◽

Cross Sectional Study ◽

Related Factors ◽

Cross Sectional ◽

Middle Income ◽

Content Type ◽

History Of

PurposeThis research aimed to explore the prevalence of musculoskeletal disorders (MSDs) and related factors among subcontracted cleaners in a teaching hospital in Thailand.Design/methodology/approachA cross-sectional study was conducted of 393 subcontracted cleaners in a teaching hospital, from May to June 2020. Face-to-face interviews were carried out using a standard questionnaire, consisting of four parts: (1) participant characteristics, (2) stress test, (3) work characteristics and (4) standardized Nordic questionnaire, Thai version, for MSDs outcome. Multiple logistic regression analyses were performed to determine the association between MSDs and related factors.FindingsThe prevalence of MSDs was 81.9%, involving mostly the lower back (57.7%), followed by the shoulder (52.6%). Factors significantly associated with MSDs were as follows: male gender (OR = 3.06, 95% CI [1.19, 7.87]), severe stress (OR = 2.72, 95% CI [1.13, 6.54]), history of injuries (OR = 4.37, 95% CI [1.27, 15.11]), mopping posture (OR = 2.81, 95% CI [1.43, 5.50]) and task duration (OR = 1.90, 95% CI [1.01, 3.57] for 2–4 h and OR = 3.39, 95% CI [1.17, 9.86] for more than 4 h). Sick leave due to MSDs was associated with history of injuries, Thai nationality and having another part-time job.Originality/valueThe study findings about MSDs in terms of prevalence and related factors contributed to limited pool of the knowledge among subcontracted hospital cleaners in Thailand and middle-income country settings. With growing popularity in outsourcing cleaning services among hospitals in these countries, the study findings could raise a concern and inform policymakers and hospital administrators the importance of the magnitude and risk factors for MSDs necessitating design of preventive strategies.

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Analysis Factors That Affecting the Incidence of Hypertension in Menopausal Woman

Jurnal Kebidanan Midwiferia ◽

10.21070/midwiferia.v6i1.449 ◽

2020 ◽

Vol 6 (1) ◽

pp. 21-25

Author(s):

Estin Gita Maringga ◽

Nunik Ike Yunia Sari

Keyword(s):

Risk Factors ◽

Statistical Data ◽

Free Variable ◽

Hormonal Contraceptives ◽

Menopausal Woman ◽

Cross Sectional ◽

Menopausal Women ◽

History Of ◽

Using Data ◽

The Village

Hypertension is an increased incidence of blood pressure characterized by the increase of sistole and diastole. Hypertension if not properly administered, can cause a variety of complications such as stroke, heart failure, renal failure, encephalopathy, and others. Based on the statistical data of menopause women risk to experience hypertension of 41% compared with males. This research aims to analyze the risk factors that affect the incidence of hypertension in menopausal women in the village Kayen Kidul. The design of research in this study uses cross sectional, with the population is all menopause women who have hypertension in the village of South Kayen, using simple random samplling technique, obtained as many as 71 respondents . The variables in this study consist of a free variable that is age and a history of the use of KB and variables bound in the form of hypertension in menopausal women. The study was conducted on 16-21 September 2019, collecting data using interview and observation techniques using data collection sheets. Data analysts use linear regression, with calculations using SPSS. The results in this study were obtained from 71 respondents, 59.2% of the mother aged < 60 years, 69% had a history of hormonal contraceptives, 57.6% menopause had hypertension. The aged menopause ≥ 60 years and has a history of hormonal contraceptives have a greater risk of hypertensive incidence in menopause.

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Etiology, Risk Factors, Mortality and Morbidity of Status Epilepticus in Children: A Retrospective Cross-Sectional Study in Tehran, Iran

The Open Neurology Journal ◽

10.2174/1874205x02014010095 ◽

2020 ◽

Vol 14 (1) ◽

pp. 95-102

Author(s):

Mohammad Vafaee-Shahi ◽

Elaheh Soltanieh ◽

Hossein Saidi ◽

Aina Riahi

Keyword(s):

Risk Factors ◽

Status Epilepticus ◽

Brain Imaging ◽

Morbidity And Mortality ◽

Cross Sectional ◽

Mortality And Morbidity ◽

Imaging Results ◽

History Of ◽

Abnormal Brain ◽

Febrile Status Epilepticus

Background: Risk factors identification associated with status epilepticus is valuable in order to prevent morbidity and mortality in children. This study aimed to consider the etiology, risk factors, morbidity and mortality in children with status epilepticus. Methods: This retrospective cross-sectional study was performed on 119 patients aged from one month old to 15 years old. Patients’ data were recorded, including basic demographic, etiology and clinical information. The different risk factors correlated to morbidity and mortality were evaluated in this study. Results: The most common etiologies were acute symptomatic and febrile status epilepticus by 32.8% and 22.7%, respectively. Abnormal brain imaging results were reported far more frequently in patients with a history of neurodevelopmental delay and previous status epilepticus (p<0.001). The overall morbidity and mortality rates were 18.9% and 10.9%, respectively; while these rates in patients with delayed development (45.16% and 18.42%, respectively) were significantly higher than patients with normal development (8% and 7.4%, respectively). The morbidity rates in patients with previous seizures and previous status epilepticus were remarkably higher than those without previous history of seizure (26.41% vs 11.32%; p=0.047) and without previous status epilepticus (36.36% versus 14.28%; p=0.018). The length of hospital stay in patients with mortality was considerably longer than patients without mortality (12.30 ± 16.1 days vs 7.29 ± 6.24 days; p=0.033). The mortality rate in patients with normal Lumbar Puncture result was notably lower than those with abnormal LP result (2.9% vs 50%). The morbidity rate in patients with abnormal brain imaging results (p<0.001) was significantly greater than those in patients with normal results. The mortality rate was relatively higher in patients with abnormal imaging results compared to those normal results. Etiology was an important predictor of mortality and morbidity rates; acute symptomatic (32.8%), febrile status epilepticus (22.7%) and remote symptomatic (16.8%) etiologies were the most common underlying causes of S.E. While in children less than 3 years old, the acute symptomatic etiology and febrile status epilepticus etiologies were estimated as the most common, in most patients older than 3 years old the most common etiology of status epilepticus was unknown. Congenital brain defects etiology had the highest mortality (36.36%) and morbidity (42.85%) rate. The lowest morbidity (3.84%) and mortality (0%) rates were for patients with febrile status epilepticus etiology. Conclusion: Age, developmental delay, history of previous status epilepticus, the length of hospital stay, abnormal brain imaging results and the underlying etiology of status epilepticus were associated with increased morbidity and mortality among children with status epilepticus.

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Screening of Gestational Diabetes and Hypertension Among Antenatal Women in Rural West India

Central Asian Journal of Global Health ◽

10.5195/cajgh.2014.140 ◽

2014 ◽

Vol 3 (1) ◽

Cited By ~ 3

Author(s):

Viral R. Dave ◽

Bhavik M. Rana ◽

Kantibhai N. Sonaliya ◽

Suraj J. Chandwani ◽

Samkit V. Sharma ◽

...

Keyword(s):

Risk Factors ◽

Gestational Diabetes ◽

Rural Areas ◽

Screening Program ◽

Cross Sectional Study ◽

Sampling Procedure ◽

Cluster Sampling ◽

Cross Sectional ◽

Screening Guidelines ◽

History Of

Background: Hypertension and gestational diabetes are among the leading causes of maternal and perinatal mortality, especially in rural areas of developing countries with meager health facilities. With early diagnosis and timely treatment, these adverse events can be decreased. The primary aim of this study was to implement a screening program for gestational diabetes and hypertension, and to assess risk factors associated with these conditions among antenatal women in the rural area of the Gujarat province in India.Methods: A cross–sectional study was conducted at one of the rural areas of Gujarat province in India. Following a random cluster sampling procedure, the village of Davas was selected. A multistage random sampling method was utilized, resulting in a sample of 346 antenatal women. Screening guidelines from the American Diabetes Association were followed for gestational diabetes screening.Results: The majority of antenatal mothers (55.50%) were between 21-25 years of age. 242 antenatal women were multigravida, and among them, 85.96% had institutional delivery at their last pregnancy. Of the total 346 women, 17.60% were prehypertensive. The prevalence of systolic hypertension was 1.40%, diastolic hypertension was 0.90%, and gestational diabetes was 1.73%.Conclusion: Socioeconomically upper class, a family history of hypertension, and BMI ≥ 25 were strong risk factors for hypertension during pregnancy and gestational diabetes. Health education should be made readily available to antenatal mothers by paramedical workers regarding symptoms of hypertension and gestational diabetes mellitus for early self identification.

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