scholarly journals STATE AND PROSPECTS USING MOLECULAR HYDROGEN FOR ATHLETES

2020 ◽  
Vol 1 ◽  
pp. 443-450
Author(s):  
Oleg Pokotylo ◽  
◽  
Ivan Zakharchuk ◽  
Borys Vykhovanets ◽  
◽  
...  
Keyword(s):  
Sports Medicine ◽  
Molecular Hydrogen ◽  
The Body ◽  
Alternative Mechanism ◽  
Physically Active ◽  
Hydrogen Water ◽  
Positive Effects ◽  
Advantages And Disadvantages ◽  
The Individual ◽  
Effective Use

Introduction. The study of molecular hydrogen as the latest therapeutic and prophylactic corrector of metabolism has been successfully tested on more than 170 models of pathological conditions. Its effective antioxidant, cytoprotective, anti-inflammatory effect on the body has been proven. Separate studies of the effects of molecular hydrogen have been conducted on athletes. The aim of the study - to investigate the level of research and efficiency of using molecular hydrogen in sports medicine and to predict the algorithm of its further research and practical use. Research Methods: Analysis, generalization of data of professional scientific literature for researching the effect of molecular hydrogen in physical culture and sports and identify opportunities and criteria for its use for athletes and physically active people Results. An analytical study based on the results of professional publications about the effective use of molecular hydrogen for athletes in the world was conducted. The advantages and disadvantages of using molecular hydrogen for the organism are reasoned. Ways and methods of entry of molecular hydrogen into the body are described. Inventions of molecular hydrogen generators of Ukrainian scientists, their advantages over foreign analogues and possibilities of their application in sports are shown. Conclusions. Today in view of the analysis of the situation with the use of molecular hydrogen for therapeutic and prophylactic purposes in medicine and sports medicine in particular, the algorithm of prospects for its further research and practical application follows. Firstly, to study the optimal protocol for the intake of molecular hydrogen, depending on the intensity of physical activity, body weight, age, sex, comorbidities, etc.; secondly, to develop personalized antioxidant strategies for the using molecular hydrogen, taking into account the individual redox characteristics of individuals; thirdly, to investigate the consequences of long-term intake of H2 during exercise; fourthly, to reveal the alternative mechanism underlying the antioxidant action and other positive effects of molecular hydrogen. Key words: sports medicine, hydrogen water, «TIG «Liwing Water»», redox potential, oxidative stress.

scholarly journals PHYSICAL TREATMENT OF SPORTS KNEE INJURIES

2018 ◽  
Vol 16 (1) ◽  
pp. 211
Author(s):  
Olivera Krstić ◽  
Milovan Stamatovic
Keyword(s):  
Sports Medicine ◽  
Sport Activity ◽  
Knee Injuries ◽  
Modern Technology ◽  
The Body ◽  
Physical Treatment ◽  
Adequate Treatment ◽  
Uneven Terrain ◽  
Positive Effects ◽  
Injured Region

The development of sports medicine and rehabilitation with the great involvement of techniques and modern technology have increased the needs and possibilities for quick diagnosis and more adequate treatment. Regular companions of sports activities are sport injuries of various parts of the body, depending on the type and conditions in which sport activity is performed. In this paper, we analyzed knee injuries because they are the most dominant. The knee, which is the largest, the most complex and the most stressed joint, is most exposed to injuries. We analyzed 124 respondents who were treated in the Ribarska Banja, by physical and balneological treatment, during the period 2005-2006. Anamnestic data, as the most common cause of injury, include insufficient training, insufficient physical preparedness, rough start of an opponent or uneven terrain. The knee joint is the most commonly injured region in athletes, and because of the complexity of the joint itself, these injuries are very complicated. Balneal treatment showed positive effects on healing and accelerated return to the field. Balneo Climatic Treatment is always accompanied with certain methods of physical therapy and rehabilitation, and all of them together can accelerate healing. The successful return to the field depends on the applied therapeutic methods and on an early beginning  of therapeutic treatment.

scholarly journals Molecular hydrogen as a possible therapeutic factor in complex rehabilitation therapy in patients with muscular skeletal disorders (literature review)

2021 ◽  
pp. 92-97
Author(s):  
Vasyl Makolinets ◽  
Tamara Grashenkova ◽  
Volodymyr Moseichuk ◽  
Kyrylo Makolinets ◽  
Vladyslav Moseichuk
Keyword(s):  
Free Radicals ◽  
Molecular Hydrogen ◽  
The Body ◽  
Matrix Proteins ◽  
Cartilage Tissue ◽  
Joint Diseases ◽  
Chain Reactions ◽  
Hydrogen Water ◽  
Normal Metabolism ◽  
The Brain

The paper presents an analysis of foreign scientific and medical data on the therapeutic factor — molecular hydrogen. The effectiveness of its application in the complex therapy of many diseases is revealed. The effect is achieved due to the small size of the mo­lecule, which passes through biological membranes and inhibits dangerous free radicals in the mitochondria, as well as in the nuc­leus, which reduces the possibility of DNA damaging. Molecular hydrogen neutralizes oxidants in the brain due to its ability to cross the blood-brain barrier. It normalizes the functions and metabolic processes in the body and, as an antioxidant, is selective: it does not affect the useful free radicals involved in important metabo­lic processes and selectively eliminates only the most dangerous oxidants — hydroxyl radicals. Interacting with them, hydrogen converts them into water molecules without the formation of by-products and chain reactions. Unlike other known antioxidants, molecular hydrogen does not disrupt normal metabolism, does not cause negative changes in cells, activates the body’s own anti­oxidant systems. The possibility and expediency of the use of molecular hydrogen in the case of pathology of the musculoskeletal system has been confirmed. The peculiarities of its effect on bone and cartilage tissue in the experiment are shown. It has been determined that the use of molecular hydrogen is a new pharmacological strategy aimed at the selective removal of ONOO—, and can be an effective method in the treatment of joint diseases. Because cartilage receives nutrients through a diffusion-loading mechanism, and molecular hydrogen penetrates rapidly into tissues, it can be useful for the prevention of diseases of joints of degenerative origin. It reduces oxidative stress and slows down the reduction of matrix proteins and inhibition of proteinase degradation. Its effectiveness has been proven after injuries to the spinal cord, muscles and tendons, comorbid diseases such as hypertension, coronary heart disease, diabetes and metabolic syndrome. Key words. Molecular hydrogen, hydrogen water, hydrogen inhalations, joint diseases, consequences of musculoskeletal injuries, comorbid pathology.

scholarly journals DISTURBANCES OF CARDIOVASCULAR SYSTEM IN PERSONS WITH CHRONIC SPINAL CORD INJURY DURING EXERCISE AND PARTICIPATION IN PARALYMPIC SPORTS

2018 ◽  
Vol 73 (4) ◽  
pp. 236-243
Author(s):  
Andrey V. Krassioukov ◽  
Evgeny V. Mashkovskiy ◽  
Evgeny E. Achkasov ◽  
Elena M. Kashchenko
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Sports Medicine ◽  
Motor Impairment ◽  
The Body ◽  
Autonomic Dysreflexia ◽  
Additional Stress ◽  
Physically Active ◽  
Essential Components ◽  
Cord Injury

Spinal cord injury (SCI) is a devastating condition that affects mostly young and active individuals but also impacts their family members and results in significant challenges for medical care and social integration. In addition to obvious motor impairment (tetraplegia/paraplegia), these individuals also suffer from a variety of less obvious but devastating autonomic nervous system dysfunctions that negatively impact their health and affect various aspects of daily living. Physical training and sports are essential components of rehabilitation and leaser activities for people with disabilities. Number of individuals with SCI who run an active lifestyle is increasing. Physical activity puts an additional stress on various organs and body systems. The presented manuscript describes in detail cardiovascular dysfunctions in physically active individuals with a SCI, including those engaged in Paralympic sports: low resting blood pressure, orthostatic hypotension, arrhythmias, and the phenomenon of «autonomic dysreflexia». We also address issues related to self-induced episodes of autonomic dysreflexia in order to improve athletic performance ― a phenomenon known as «boosting». Boosting may improve sports performance in short term but is associated with the risk of serious cardiovascular disorders and even sudden death. This practice is considered as anti-doping rule violation by the International Paralympic Committee and thus prohibited. Understanding of the changes occurring in the body of a physically active individual after SCI is necessary for general practitioners, neurologists, rehabilitation specialists, sports medicine physicians, as well as for specialists of adapted physical education and sports.

scholarly journals Correlation Between Monitoring Practices During Anesthesia and Patient Recovery

2021 ◽  
pp. 1-4
Author(s):  
Tariq No’aman Al-Shurbaji
Keyword(s):  
Blood Pressure ◽  
General Anesthesia ◽  
Treatment Process ◽  
Healthcare Professionals ◽  
The Body ◽  
Noninvasive Blood Pressure ◽  
Advantages And Disadvantages ◽  
Monitoring Process ◽  
Anesthesia Monitoring ◽  
The Individual

Anesthesia is used by healthcare professionals to induce loss of sensation in the body of the patient so that the surgical process of treatment is carried out effectively. Anesthesia doses that are given to patients have been classified into three types which are general anesthesia, sedation anesthesia, and regional or local anesthesia. These medications are given to patients as per the severity of the injury and treatment process. The provision of anesthesia includes monitoring processes such as Electrocardiography (ECG), Noninvasive Blood Pressure (NIBP), pulse oximetry, and others so that patient safety is ensured at all the levels of treatment. It also includes Depth of General Anesthesia (DGA) is an advanced monitoring process of anesthesia through which accurate drug administration in the individual patient is executed. The study introduces current prospects of anesthesia monitoring and mentions details about important methods and technologies in use and their both advantages and disadvantages. It also provides details about DGA and other latest upcoming methods for anesthesia monitoring.

scholarly journals Influence of probiotic complex on productive performance and metabolism in growing pigs

2020 ◽  
pp. 22-26 ◽  
Author(s):  
I. M. Magomedaliyev ◽  
R. V. Nekrasov ◽  
M. G. Chabaev ◽  
V. V. Dzhavakhiya ◽  
E. V. Glagoleva ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Growing Pigs ◽  
Feed Additives ◽  
The Body ◽  
Farm Animals ◽  
Processing Plant ◽  
Science Center ◽  
Positive Effects ◽  
Young Pigs ◽  
Effective Use

Topicality. To date, an extensive scientific and practical material has been accumulated to study the effectiveness of probiotic feed additives in the feeding of farm animals. Some mechanisms of their action on the animal body have been studied, positive effects have been established, which are expressed in improving the microbial balance of the intestine, increasing the protective properties of the body, and realizing the productive qualities of animals. It is necessary to study the effectiveness of the use of probiotic complexes in comparison with the action of antibiotic-containing drugs.Methodology. It was studied the probiotic complex of Enzymsporin containing a consortium of bacteria of the genus Bacillus (Bacillus subtilis VKM B-2998 D, Bacillus licheniformis VKM B-2999 D, Bacillus subtilis VKM B-3057D) at least 5x109 CFU/g was studied in comparison with antibiotic-containing drug Virginiamycin in feeding fattened young pigs. The studies were carried out on four groups (30 heads in each group) of growing pigs in the conditions of LLC “Bryansk meat processing plant” and in the laboratories of L.K. Ernst Federal Science Center for Animal Husbandry. The duration of the experiment was 113 days.Results. During the studies, the control group of animals received compound feeds without probiotic additives, while the animals of the 2nd and 3rd experimental groups received compound feed with the addition of probiotic complex in an amount of 0.5 and 1.0 kg/t, the 4th experimental group of pigs received compound feed with the addition of antibiotic-containing drug Virginiamycin 250 g/t. By the end of the study, the live weight and average daily increments of experimental animals increased by 5.0; 6.0; 10.02 and 5.8; 6.5; 12.2% (p < 0.001), respectively, compared with the control. Biochemical, morphological, immunological blood indices corresponded to physiological norms, the inclusion in the feed of pigs fed different levels of probiotic complex has led to a significant increase lysozyme, bactericidal and phagocytic activity of blood in animals 2nd and 3rd groups during rearing. Additional profit for the period of research was in the experimental groups of fattened young pigs +705,0; +849,0 and 1440.0 rubles/ head, accordingly, in comparison with the control, which indicates the effective use of not only antibiotic-containing drugs in feeding pigs, but also suggests the effective use of probiotics instead of antibiotic-containing feed preparations.

scholarly journals Wave energy devices with compressible volumes

2014 ◽  
Vol 470 (2172) ◽  
pp. 20140559 ◽  
Author(s):  
Adi Kurniawan ◽  
Deborah Greaves ◽  
John Chaplin
Keyword(s):  
Wave Energy ◽  
The Body ◽  
Period Range ◽  
Energy Devices ◽  
Positive Effects ◽  
Advantages And Disadvantages ◽  
Air Turbine ◽  
Absorbed Power ◽  
The First Variation ◽  
The Second Variation

We present an analysis of wave energy devices with air-filled compressible submerged volumes, where variability of volume is achieved by means of a horizontal surface free to move up and down relative to the body. An analysis of bodies without power take-off (PTO) systems is first presented to demonstrate the positive effects a compressible volume could have on the body response. Subsequently, two compressible device variations are analysed. In the first variation, the compressible volume is connected to a fixed volume via an air turbine for PTO. In the second variation, a water column separates the compressible volume from another volume, which is fitted with an air turbine open to the atmosphere. Both floating and bottom-fixed, axisymmetric, configurations are considered, and linear analysis is employed throughout. Advantages and disadvantages of each device are examined in detail. Some configurations with displaced volumes less than 2000 m 3 and with constant turbine coefficients are shown to be capable of achieving 80% of the theoretical maximum absorbed power over a wave period range of about 4 s.

scholarly journals Possibilities of carboxytherapy for diseases of the cardiovascular system

2020 ◽  
pp. 31-38
Author(s):  
S. M. Drogovoz ◽  
L. B. Ivantsyk ◽  
Yu. V. Stoletov ◽  
A. L. Shtroblya ◽  
A. V. Kononenko ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Clinical Evidence ◽  
Evidence Base ◽  
The Body ◽  
Foreign Experience ◽  
Analgesic Effects ◽  
Positive Effects ◽  
Anti Oxidant ◽  
Carbon Dioxide Co2 ◽  
Effective Use

The aim of the study was to analyze the mechanisms of action and pharmacodynamics of carboxytherapy in diseases of the cardiovascular system (CVS). Materials and methods. An analysis of domestic and foreign experience in the use of carboxytherapy for diseases of CVS. Results and discussions. The mechanism of action of carboxytherapy is based on the principle of the introduction of carbon dioxide (CO2) in the patient's body, due to which many pathological disorders can be eliminated. Inhalation and non-inhalation introduction of CO2 into the body has been used for medicinal purposes for many decades. The empirical (off label) use of this therapy in course of time has gained a wide clinical evidence base. There is a large amount of clinical evidence in the world of the effective use of carboxytherapy in many fields of medicine, including those with CVS diseases. It is proved that CO2 introduced into the body penetrates freely through cell membranes and has antihypoxic, vasodilating, antioxidant, anti-ischemic, antispasmodic and other positive effects. Therefore, carboxytherapy contributes to a complex of pharmacological effects inherent of traditional antianginal, hypotensive, antispasmodic and other drugs that are widely used in the treatment of CVS diseases. Conclusions. An analysis of domestic and foreign experience in carboxytherapy shows that the effects of CO2 in diseases of the CVS are achieved by improving oxygenation and microcirculation, anti-anginal, anti-inflammatory, antihypertensive, antispasmodic, anti-oxidant, and analgesic effects of this gas. Carboxytherapy is an alternative, promising and safe method of treating diseases of the cardiovascular system.

scholarly journals MOLECULAR HYDROGEN GENERATOR GVCH LIFE

2021 ◽  
pp. 65-68
Author(s):  
Volodymyr Moseichuk ◽  
Vladyslav Moseichuk ◽  
Vasyl Makolinets
Keyword(s):  
Musculoskeletal System ◽  
Molecular Hydrogen ◽  
Water Concentration ◽  
Hydrogen Gas ◽  
The Body ◽  
Water Volume ◽  
Antioxidant Systems ◽  
Pure Hydrogen ◽  
Hydrogen Generator ◽  
Hydrogen Water

Molecular hydrogen is one of the effective antioxidants, which not only does not disrupt normal metabolism in the body, but also activates its antioxidant systems. Hydrogen-saturated water has  antioxidant, anti-inflammatory, anti-allergic, anti-apoptotic properties, stimulates energy metabolism and contributes to the systemic recovery of the body. It is used as a therapeutic factor for the treatment of patients with various pathologies: arterial hypertension, coronary heart disease, diabetes, obesity, metabolic disorders, disorders of the musculoskeletal system. The article discusses the various methods of obtaining molecular hydrogen and hydrogen water (direct and indirect saturation). Technical characteristics are described and features of the hydrogen generator GVCh Life (manufacturer LTD «Chemtest Ukraine+», Kharkiv, Ukraine), which produces molecular hydrogen (purity of which is 99.99 %, productivity — 100 ml/min) and saturates water with it (https://chemtest.com.ua/generator_vodorodnoy_vodi_i_dihanie_gvch_life). In contrast to the problems of most known generators in the device GVChLife is completely no contact of the electrodes with water, so it is not subject to electrolysis and is not saturated with metal ions. Water saturated in this way has the following characteristics: redox potential 560 mV, hydrogen concentration 1.0–1.15 ppm(water volume 1 l, saturation duration 10 min). The generator can be used for both hydrogen saturation and hydrogen inhalation. In the case of therapeutic use of hydrogen water to obtain it, you can use any drinking water (spring, prepared or non-carbonated bottled), hydrogen inhalation using nasal cannulas. Inhalation of pure hydrogen gas (99.99 %) for 30 minutes is equal to the use of 15 liters of hydrogen water (concentration 1.1–1.2 ppm). Conclusions. The developed MoHC Life molecular hydrogen generator is safe to use, without special requirements during operation. It can be successfully used in the complex therapy of patients with various diseases, including musculoskeletal system.

Multidisciplinary management of vascular access for haemodialysis: from the preparation of the initial access to the treatment of stenosis and thrombosis

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 188-198 ◽  
Author(s):  
Reinhold ◽  
Haage ◽  
Hollenbeck ◽  
Mickley ◽  
Ranft
Keyword(s):  
Vascular Access ◽  
Central Venous ◽  
Advantages And Disadvantages ◽  
Multidisciplinary Study ◽  
First Results ◽  
Lower Complication ◽  
Lower Complication Rate ◽  
Access Problems ◽  
Arteriovenous Grafts ◽  
The Individual

In February 2008 a multidisciplinary study group was established in Germany to improve the treatment of patients with potential vascular access problems. As one of the first results of their work interdisciplinary recommendations for the management of vascular access were provided, from the creation of the initial access to the treatment of complications. As a rule the wrist arteriovenous fistula (AVF) is the access of choice due to its lower complication rate when compared to other types of access. The AVF should be created 3 months prior to the expected start of haemodialysis to allow for sufficient maturation. Second and third choice accesses are arteriovenous grafts (AVG) and central venous catheters (CVC). Ultrasound is a reliable tool for vessel selection before access creation, and also for the diagnosis of complications in AVF and grafts. Access stenosis and thrombosis can be treated surgically and interventionally. The comparison of both methods reveals advantages and disadvantages for each. The therapeutic decision should be based on the individual patients’ constitution, and also on the availability and experience of the involved specialists.

Influence of stable iodine on the uptake of the thyroid – model vs. experiment

2001 ◽  
Vol 40 (01) ◽  
pp. 31-37 ◽  
Author(s):  
U. Wellner ◽  
E. Voth ◽  
H. Schicha ◽  
K. Weber
Keyword(s):  
Time Course ◽  
Compartment Model ◽  
The Body ◽  
Iodine Uptake ◽  
Model Calculations ◽  
Physiological Conditions ◽  
Iodine Supply ◽  
Predicted Values ◽  
The Individual ◽  
Stable Iodine

Summary Aim: The influence of physiological and pharmacological amounts of iodine on the uptake of radioiodine in the thyroid was examined in a 4-compartment model. This model allows equations to be derived describing the distribution of tracer iodine as a function of time. The aim of the study was to compare the predictions of the model with experimental data. Methods: Five euthyroid persons received stable iodine (200 μg, 10 mg). 1-123-uptake into the thyroid was measured with the Nal (Tl)-detector of a body counter under physiological conditions and after application of each dose of additional iodine. Actual measurements and predicted values were compared, taking into account the individual iodine supply as estimated from the thyroid uptake under physiological conditions and data from the literature. Results: Thyroid iodine uptake decreased from 80% under physiological conditions to 50% in individuals with very low iodine supply (15 μg/d) (n = 2). The uptake calculated from the model was 36%. Iodine uptake into the thyroid did not decrease in individuals with typical iodine supply, i.e. for Cologne 65-85 μg/d (n = 3). After application of 10 mg of stable iodine, uptake into the thyroid decreased in all individuals to about 5%, in accordance with the model calculations. Conclusion: Comparison of theoretical predictions with the measured values demonstrated that the model tested is well suited for describing the time course of iodine distribution and uptake within the body. It can now be used to study aspects of iodine metabolism relevant to the pharmacological administration of iodine which cannot be investigated experimentally in humans for ethical and technical reasons.

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