TO STUDY THE INFECTIVE PROFILE OF PATIENTS WITH EAR INFECTIONS IN TERTIARY CARE HOSPITAL BIHAR: AN OBSERVATIONAL STUDY.

Aim: to study the infective profile of patients with ear infections. Materials and Methods: The present prospective observational study was conducted in the Department of ENT, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar, India .Among 200 patients attended the OPD of the ENT presented with ear infection/discharge. Aural discharge samples collected through a sterile culture sensitivity tube and sent to microbiological lab and culture sensitivity reports collected from the patients during follow up visits. Results: majority of participants were in the age group between 1 and 20 years. 60.5% of the patients had ear discharge for ≥14 days. The prevalence of ear infection among females (53.5%) was slightly higher than males (46.5%). Gram negative organisms are detected in (47.0%), Gram positive organisms detected (34.5%), fungal infection detected (6.0%) and no organism detected (12.5%) of the aural swab samples. Conclusion: The profile and predominant bacteria isolated highlights the need for continuous surveillance and reporting of the microbiology of ear infection in our local community in order to guide clinicians use the appropriate antimicrobials towards the incriminated etiologies. Keywords: culture, sensitivity, ear infection

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AN AN OBSERVATIONAL STUDY OF PRESCRIPTION PATTERN OF DRUGS FOR OSTEOARTHRITIS IN A NORTH INDIAN MEDICAL COLLEGE

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2019.v12i7.33882 ◽

2019 ◽

pp. 308-310

Author(s):

ASHWANI UMMAT ◽

RANJODH JEET SINGH ◽

SONIA KOCHHAR

Keyword(s):

Observational Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Oral Route ◽

Care Hospital ◽

Age Group ◽

Cross Sectional ◽

Prescription Pattern ◽

Medical College ◽

Indian Medical

Objective: The objective of the study is to analyze the prescription pattern of drugs for osteoarthritis (OA) in a north Indian medical college collaborated with a tertiary care hospital. Methods: An observational study was conducted on 300 patients diagnosed with OA in the department of orthopedics in collaboration with the department of pharmacology, and thus, prescription was collected as in a cross-sectional manner for 6 months and the same were analyzed in the Department of Orthopedics in tertiary care hospital collaborated with medical college. Results: The average age of patients participating in this present study was 56.46±7.4 years with affected age group of 46-60 years. 60 % of females were affected by osteoarthritis outnumbering male (40 %) patients in this present study. The most commonly involved joint was knee joint (87.33 %) in patients diagnosed with osteoarthritis followed by back (6.67 %) and hip joint (6%). The combination therapy (90 %) outweighed monotherapy (10 %) with preferred route of drug administration as oral route (90 %) followed by topical route (10 %). The average number of drugs prescribed for patients of osteoarthritis was 2.62±0.76. This present study concludes that NSAIDs (45.8%) were prescribed most commonly. However, the drug paracetamol was lesser prescribed and other drugs such as Diclofenac (27.22 %) and acetaminophen (34.44 %) most of all followed by Nimesulide (16.67 %), ibuprofen (13.33 %) and Rofecoxib/valdecoxib (8.33 %) were prescribed. Conclusion: This present study concludes that NSAIDs were most commonly prescribed as p-drugs while paracetamol was undermined prescribed.

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Low birth weight: an observational study of maternal and neonatal factors in a rural tertiary care hospital, Telangana, India

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20212671 ◽

2021 ◽

Vol 10 (7) ◽

pp. 2799

Author(s):

Murty V. R. Nabhi ◽

Ramjyoti S. ◽

Vydehi B. ◽

Vasantha K. ◽

Vijayalakshmi Gillella

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Observational Study ◽

Tertiary Care ◽

Antenatal Visit ◽

Care Hospital ◽

Medical College ◽

High Infant Mortality ◽

Quality Health ◽

Nicu Admission

Background: Poor maternal health among Indian women is of global significance because India is home to 1/5th of the world’s births. 27% of these newborn babies in India are low birth weight (LBW), an important cause of high infant mortality. This study was conducted among puerperal women who delivered LBW babies in our hospital to know the various factors pertaining to socio-demographic, obstetric and anthropometric characteristics.Methods: this observational study was conducted in the department of obstetrics and gynecology at Bhaskar medical college and hospital, Moinabad, Hyderabad from January 2016 to June 2017. The study sample were those who delivered LBW babies in our hospital and a set questionnaire was used to collect the relevant details.Results: 75% of these mothers were in the age group of 20-25 years, 73.5% had more than 10 years of schooling. About 64% of these women had their 1st antenatal visit in 1st trimester of pregnancy and 54% had their 1st ultrasound in 1st trimester. 36 babies had NICU admission, either at our hospital or at a level III NICU facility, and all had good neonatal outcome.Conclusions: The state must endeavor to make quality health free and easily accessible to pregnant women so that all can avail these services to better the maternal and neonatal outcomes. This will be helpful in improving the overall health of our population over the next few decades.

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Bacterial etiology of otitis media and their antibiogram among patients attending tertiary care hospital

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20203557 ◽

2020 ◽

Vol 6 (9) ◽

pp. 1604

Author(s):

Ashish Sharma ◽

Nagababu Pyadala

Keyword(s):

Otitis Media ◽

Social Adjustment ◽

Tertiary Care ◽

Care Hospital ◽

Bacterial Isolates ◽

Older Children ◽

Ear Infection ◽

Medical College ◽

Sensitivity Report ◽

System Disorder

Background: Otitis media is one of the common infection prevalent worldwide. Chronic ear infection in older children can cause hearing loss which leads difficulty in communication, learning and social adjustment. It can result to severe disability, death due to central nervous system disorder in developing countries. Hence, the present study aimed to determine the bacteriological profile and its antibiogram of ear infection.Methods: This study conducted in ENT department of MNR Medical College and Hospital during the period of October 2019 to January 2020. Results: A total of 120 patients were included in this study. Among the total, 70 were adult (58.3%), age group ranges between 20-55 years and 50 were children (41.6%). Bacterial isolates from ear swab included; Staphylococcus aureus 28, Pseudomonas 19, Klebsiella spp 15, Proteus spp 10, Escherichiae coli 7, Enterobacter spp 4 and Citrobacter spp 2. Overall bacteria mostly sensitive to drugs like pipercillin tazobactum (85%), amikacin (90%) and gentamycin (90.2%). Other than these drugs ampicillin (90.1%), cefazolin (90%), cefuroxime (89.4%), ceftriaxone (81%), oxacillin (83.4%), penicillin (88.2%) showed highly resistant to bacterial isolates.Conclusions: Therefore, it is clear from this study that, most of the prescribed drugs were resistant to bacteria isolated from ear infection. Hence it is mandatory to include culture and sensitivity report to manage the cases of otitis media.

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Isolation of ESBL producing organisms by Double Disc Synergy Test in tertiary care hospital

Bangladesh Journal of Medical Microbiology ◽

10.3329/bjmm.v7i2.19330 ◽

2013 ◽

Vol 7 (2) ◽

pp. 21-24

Author(s):

Mili Rani Saha ◽

Sanya Tahmina Jhora ◽

Shikha Paul ◽

Durdana Chowdhury

Keyword(s):

Tertiary Care ◽

Care Hospital ◽

Burn Wound ◽

Gram Negative ◽

Medical College ◽

Wound Swab ◽

Synergy Test ◽

Gram Negative Organisms ◽

Klebsiella Spp ◽

Esbl Producers

Extended spectrum beta-lactamase (ESBL) producing organisms pose unique challenges to clinical microbiologists, clinicians, infection control professionals and antibacterial discovery scientists. The study was done to determine ESBL producing strains by a most feasible and accurate phenotypic method. Urine, surgical wound swab, burn wound swab and pus samples were taken from Sir Salimullah Medical College and Mitford Hospital and from Burn Unit of Dhaka Medical College Hospital from January 2011 to December 2011. ESBL producers were detected by Double Disc Synergy Test. From 354 different samples, 59.04% organisms were isolated. Among them 89% were Gram-negative organisms. Out of these Gram-negative organisms 41.40% isolates were ESBL producers. Among them 75% were Klebsiella spp. and 41.67% were Esch coli. This study shows that the frequency of ESBL producing strains of Esch. coli and Klebsiella spp. is high in both hospitals and it has a significant inference for patient's management. Hence, it is very important that a doctor should be familiar with the clinical significance of these enzymes and potential strategies for dealing with this growing problem.DOI: http://dx.doi.org/10.3329/bjmm.v7i2.19330 Bangladesh J Med Microbiol 2013; 07(02): 21-24

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Maternal and perinatal outcome in placenta previa: an observational study at a tertiary care hospital in Mysore, Karnataka, India

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20190978 ◽

2019 ◽

Vol 8 (4) ◽

pp. 1322

Author(s):

Maunica Reddy Sorakayalapeta ◽

Nandish S. Manoli

Keyword(s):

Observational Study ◽

Perinatal Outcome ◽

Placenta Previa ◽

Tertiary Care ◽

Morbidity And Mortality ◽

Care Hospital ◽

Perinatal Morbidity ◽

Medical College ◽

Clinical Complications ◽

History Of

Background: 2-5% of the pregnancies are complicated by antepartum haemorrhage. About one third of them are due to placenta previa thus contributing to a significant amount of maternal and perinatal morbidity and mortality. In the present times with liberally increasing caesarean section rates, there is a changing trend in the incidence and complications of placenta previa. The objective of this study was to evaluate the obstetrical characteristics and maternal and perinatal outcome of cases of placenta previa.Methods: This was a prospective observational study conducted in the Department of Obstetrics and Gynaecology of JSS Medical College and Hospital, Mysore during the period January 2017 to June 2018.Results: Out of total 13,150 deliveries during this period, placenta previa was observed in 131 cases with an incidence of 1%. Majority belonged to the age group 25-29 years (48.8%). 66% of the cases presented with painless vaginal bleeding as their chief complaint. The major risk factor was previous caesarean delivery seen in 29.8% cases followed by history of abortion in 18.3%. 67% cases had major degree placenta previa. Remaining 33% cases had minor degree. One case was complicated by placenta accrete. Peripartum hysterectomy was performed in 3.1%. Preterm deliveries amounted to 29.8%. Maternal and perinatal mortality were 0.76% and 3.05% respectively. 10.7% cases had Postpartum haemorrhage and 3.8% required ICU admission. 25% neonates required NICU admissions and 10% had RDS.Conclusions: Placenta previa is a prime contributor to substantial maternal and perinatal morbidity and mortality. Early referral to tertiary care centres, anticipation of clinical complications and appropriate measures can avoid grave consequences. Such cases must always be managed at a higher centre with good NICU services and round the clock operation theatre and blood bank facility.

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Detection of SHV Gene from Extended-Spectrum Beta-Lactamases (ESBLs) Producing Isolates in a Tertiary Care Hospital

Bangladesh Journal of Medical Microbiology ◽

10.3329/bjmm.v8i2.31093 ◽

2017 ◽

Vol 8 (2) ◽

pp. 14-18

Author(s):

Mili Rani Saha ◽

Sanya Tahmina Jhora ◽

Tarek Mahbub Khan ◽

Shikha Paul ◽

Durdana Chowdhury

Keyword(s):

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Gram Negative ◽

Beta Lactamases ◽

Medical College ◽

Extended Spectrum Beta Lactamases ◽

Synergy Test ◽

Gram Negative Organisms ◽

Klebsiella Spp

Most ESBL Extended-Spectrum beta-lactamases (ESBLs) producing isolates carry TEM and SHV type betalactamases. Among these two types beta-lactamases SHV type was reported nosocomial infection outbreak in many countries in the world. The goal of this study was to see the rate of ESBLs production and also to detect SHV gene in those isolates recovered from a tertiary care hospital. A total of 354 samples were collected from Sir Salimullah Medical College and Mitford Hospital and from Burn Unit of Dhaka Medical College Hospital from January 2011 to December 2011. To detect ESBLs, Gram-negative organisms were subjected to Double Disc Synergy Test and SHV gene was detected from those ESBLs producing microorganisms by PCR. In this study, out of 354 different clinical samples 186 (89%) were Gram-negative organisms. Among of these Gramnegative organisms 77 (41.40%) were ESBL producing isolates detected by Double Disc Synergy Test. Out of these 77 isolates, 8 isolates (10.38%) carried bla SHV gene. Among those ESBL producing 26.26% Klebsiella spp. (4 out of 15 isolates) had SHV gene. Our findings showed that the majority of the ESBLs positive clinical isolates were Klebsiella spp. and high frequency of SHV genes were found in Klebsiella spp.Bangladesh J Med Microbiol 2014; 08 (02): 14-18

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Study of infective profile of patients with ear infections in lower Himalayan region

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20201001 ◽

2020 ◽

Vol 6 (4) ◽

pp. 642

Author(s):

Manjeet Singh

Keyword(s):

Staphylococcus Epidermidis ◽

Regional Hospital ◽

Himalayan Region ◽

Living Standard ◽

Ear Infection ◽

Major Health Problem ◽

Major Health ◽

Sterile Culture ◽

Culture Sensitivity ◽

Ear Infections

Background: An ear infection is a bacterial, viral and fungal infection of the external or middle ear. The aim of the study was to study the infective profile of patients with ear infections in lower himalayan region.Methods: 100 patients with ear infections/ear discharge were included in the study. Aural discharge samples collected through a sterile culture sensitivity tube and sent to microbiological lab in the Regional Hospital Bilaspur (SRL diagnostics). Results: Out of total 100 ears swab samples examined Staphylococcus aureus (35%) was the commonest infecting organism followed by Pseudomonas aeruginosa (25%), mould (10%), Staphylococcus epidermidis (06%), Escherichia coli (05%) and Klebsiella pneumoniae (05%).Conclusions: Prevalence of ear infection is a major health problem in developing countries due to the poor living standard and hygienic conditions.

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SEROPREVALENCE OF HIV AND HBsAg AMONGST BLOOD DONORS IN A TERTIARY CARE HOSPITAL, CHHATTISGARH.

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v3i8.495 ◽

2019 ◽

Vol 3 (8) ◽

Author(s):

Anusha P ◽

Bankar Nandkishor J ◽

Karan Jain ◽

Ramdas Brahmane ◽

Dhrubha Hari Chandi

Keyword(s):

Hepatitis B ◽

Blood Donors ◽

Hepatitis B Surface Antigen ◽

Tertiary Care ◽

Laboratory Diagnosis ◽

Blood Bank ◽

Care Hospital ◽

Medical College ◽

The World ◽

First Time

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.

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