scholarly journals COMPARATIVE EVALUATION OF THE EFFICACY OF DIODE LASER, GLUMA DESENSITIZER AND DESENSITIZING MOUTH RINSE IN THE TREATMENT OF DENTINE HYPERSENSITIVITY – CLINICAL STUDY

Author(s):  
Sai Chandra Goud ◽  
Prerna Kataria ◽  
Pradeep Shukla ◽  
Gaurav Malhotra ◽  
Varun Dahiya ◽  
...  

Introduction: Dentine hypersensitivity is characterized by acute, sharp pain arising from the exposed dentine, most commonly in response to thermal, tactile, or chemical stimuli, and which cannot be linked to any other pathological changes in the tooth or the environment. Therapy uses various impregnating agents in the form of solutions or gels and, in more recent times, lasers. Gluma Desensitizer, Desensitizing mouthrinse has been used previously in a dentifrice or gel to alleviate dentinal hypersensitivity. Aim: To compare the efficacy of Diode laser, Gluma desensitizer and desensitizing mouth rinse in the treatment of dentine hypersensitivity. Materials and Methods: The study contained 60 individuals (42 males and 18 females) of dentinal hypersensitivity. There were three groups in the study i.e., patients treated with laser, Gluma Desensitizer and Desensitizing mouth rinse. Before starting any treatment, the hypersensitivity was checked with the help of cold air blast and probe test according to VAS (Visual analog scale) the responses were evaluated from the patients. Results: Group I (Laser) showing the highly significant results compared to group 2 (Gluma desensitizer) and group 3 desensitizing mouth rinse (3% Potassium Nitrate) in decreasing the dentinal hypersensitivity. Keywords: dentine hypersensitivity, desensitizing agent, diode laser, laser therapy. Gluma Desensitizer; mouth rinses

Author(s):  
Aman Mallick ◽  
Gaurav Malhotra ◽  
Pradeep Shukla ◽  
Prerna Kataria ◽  
C. S Joshi

Introduction: Dentine hypersensitivity (DH) occurs on exposed dentine and is dependent on the patency of dentinal tubules. This study compared the effectiveness of toothpaste containing Strontium Chloride, Novamine, Pro-Arginine in occluding dentine tubules along with comparision of those. Materials and Method: 45 freshly extracted teeth were randomly divided (15 each) into 3 groups: Group 1 15 Teeth treated with toothpaste containing Strontium Chloride. Group 2 15 Teeth treated with toothpaste containing Novamine Group 3 15 Teeth treated with toothpaste containing Pro-Arginine. Each specimen was brushed with the dentifrice slurries and examined under SCM. Result: The mean of occluded dentinal tubules on the dentin surface after brushing with three dentifrices were significant among them Pro-arginine group showed maximum occlusion. Conclusion: The present in vitro SEM study results revealed that:  All the experimental agents– Strontium chloride, novamin, Pro- Argenine were effective in occluding dentinal tubules & the percentage (%) of occluded tubules was found to be highest for Pro- Argenine as compared to the other groups. Keywords: SCM, DH


1996 ◽  
Vol 8 (2) ◽  
pp. 279 ◽  
Author(s):  
RC Fry ◽  
MA Driancourt

The changes in follicle-stimulating hormone (FSH) concentration required to affect follicle growth and ovulation rate within individual ewes were examined. Relationships between peripheral FSH concentrations during the late-luteal and follicular phase and subsequent ovulation rates were investigated in 22 ewes from 4 breeds over 3 successive cycles (Experiment 1). Ewes were grouped as follows: Group 1 (n = 6), ewes exhibiting the same ovulation rate at each oestrous cycle: Group 2 (n = 5), ewes with three different ovulation rates at each oestrous cycle; and Group 3 (n = 11), ewes with the same ovulation rate at two oestrous cycles and a different ovulation rate on one occasion. Data from ewes in Group 1 and 3 provided estimates on the variation in FSH concentrations between cycles which were not large enough to alter ovulation rate (range, 0-67% variation in FSH concentration). In Group-2 ewes, there was no consistent association between increases in ovulation rate and the proportional increases in FSH concentrations. Differences in FSH concentrations were often less than those that did not alter ovulation rate in Group-I ewes. Furthermore, only 3 of 11 Group-3 ewes demonstrated high FSH concentrations associated with high ovulation rate (or low FSH concentrations and low ovulation rate) when compared with the concentrations found at the two cycles in which ovulation rate was similar. Hence, there was little evidence that FSH concentrations during the late-luteal and follicular phase are associated with changes in ovulation rate within individual ewes. In Experiment 2, follicles of similar size obtained from the same ewe (FecBFec+ and Romanov) showed markedly different responses in vitro to graded doses of FSH as measured by aromatase activity. It is concluded that, within a ewe, the large variability between gonadotrophin-dependent follicles in their requirement for FSH prevented the expression of any thresholds of ovarian response to FSH.


PEDIATRICS ◽  
1975 ◽  
Vol 55 (4) ◽  
pp. 507-516
Author(s):  
Mary Ellen B. Wohl ◽  
N. Thorne Griscom ◽  
Demetrius G. Traggis ◽  
Norman Jaffe

To determine the long-term effects of therapeutic pulmonary irradiation and treatment with actinomycin D during a period of lung growth, 12 patients treated for Wilms' tumor metastatic to the lung and 8 patients treated for Wilms' tumor with no evidence of pulmonary metastases were studied 7 to 14 years after their initial tumor therapy. All patients had received irradiation to the tumor bed and treatment with actinomycin D. Group I had received a single course of bilateral pulmonary irradiation; group 2 had received additional pulmonary irradiation and/or thoracic surgery; group 3 had received no therapeutic irradiation directed primarily to the chest. Total lung capacity (TLC) averaged 71% of predicted value in group 1,58% in group 2, and 94% in group 3. Diffusing capacity in groups 1 and 2 was reduced to the same extent as lung volume. Quasi-static pressure-volume relationships, studied in three of six patients in group 1, were within the normal range when lung volume was expressed as percentage of observed TLC. Airway resistance, evaluated by spirometry, maximum expiratory flow-volume curves, and resistance of the total respiratory system, was normal or reduced. The data support the hypothesis that therapeutic irradiation during a period of lung growth primarily affects the lung parenchyma and produces a decrease in subsequent size of both the lung and chest wall. No effect of actinomycin D alone upon the lung could be demonstrated.


2020 ◽  
Vol 22 (1-2) ◽  
pp. 33-38
Author(s):  
Rojin Joshi ◽  
S Gautam ◽  
B Joshi

Dentinal hypersensitivity has been defined as a short, sharp pain arising from exposed dentine in response to stimuli thermal, evaporative, tactile, chemical or osmotic and which cannot be ascribed to any other form of dental defect or pathology. This is a common clinical condition which may cause patients more distress due to exposure of dentin. There are various management options for this clinical condition which can be either home applied or in office techniques. Various dentifrices are commercially available in the market. The chemical compositions of the dentifrices are different. We conducted this study to compare the effectiveness of a potassium nitrate containing dentifrice and a Novamin based dentifrice in relieving dentinal hypersensitivity. The patients were divided into two experimental groups; group 1-potassium nitrate containing dentifrice and group 2-Novamin containing dentifrice. The sensitivity score was analyzed by using a verbal rating scale at baseline, at three weeks and at six weeks after using the dentifrices. Statistical analysis was done using SPSS version 17. Chi-square test showed that there was no significant difference between the effectiveness and efficacy of the two dentifrices. The results were highly significant (p<0.001). Hence, potassium nitrate and Novamin were equally effective in reducing dentinal hypersensitivity.


2017 ◽  
Vol 9 ◽  
pp. 176 ◽  
Author(s):  
Diah Ayu Maharani ◽  
Alia Ramadhani ◽  
Melissa Adiatman ◽  
Yuniardini Septorini Wimardhani ◽  
Linda Kusdhany ◽  
...  

Objective: This study aimed at comparing the antiplaque, anticalculus, and antigingivitis potentials of a mouth rinse containing essential oil, alcohol,zinc, and fluoride with a mouth rinse containing cetylpyridinium chloride (CPC) 0.1% over 1-, 2-, and 3-month periods.Methods: This study was a double-blind, parallel randomized clinical trial with a 3-day run-in phase. Respondents were asked to gargle twice dailywith 15 ml of mouth rinse for 30 seconds after brushing teeth. Respondents were 80 females with a mean age of 21 years, and a single dental examinerwas employed throughout the study to decrease the variance. Prophylaxis was performed for all respondents before the intervention. Three mouthrinses were tested: Group 1 with the mouth rinse containing CPC 0.1%, Group 2 as the negative control, and Group 3 as the positive control with amouth rinse containing alcohol. Evaluations were conducted by plaque index, gingival index, calculus index, and CariScreen examinations.Results: The clinical trial showed that the mouth rinse with alcohol and the mouth rinse containing CPC 0.1% were effective in inhibiting bacterialbuildup (antiplaque) and have anticalculus properties, but with no statistically significant antigingivitis effect.Conclusion: It was found that the mouth rinse containing alcohol has similar effectiveness with CPC 0.1% mouth rinse, but side effects, such as aburning sensation, were reported in the alcohol-containing mouth rinse.


Author(s):  
Sonja H. M. Derman ◽  
Eva-Maria Lantwin ◽  
Anna Greta Barbe ◽  
Michael J. Noack

Abstract Objectives Pain is affecting acceptance of supportive periodontal therapy and primary periodontitis prevention. Our objective was to evaluate the efficacy of a 1-week pre-treatment use of dentinal-hypersensitivity-reducing mouth-rinses (DHM) in periodontal maintenance (SPT) or dental prophylaxis patients. Material and methods One hundred fifty-five participants attending for professional mechanical plaque removal (PMPR) were randomly assigned to use a mouth-rinse twice daily for 1 week prior to their next PMPR. Rinses were containing either potassium oxalate (n = 52), arginine (n = 52), or herbal extracts (n = 51). At baseline and reassessment, procedural pain was assessed by visual analogue scale (VAS) and verbal rating scale (VRS). Self-reported efficacy was documented. Results No inter-group differences were estimated between both test groups and the control for baseline and reassessment means (VAS, VRS). In the SPT group, VAS reduction and self-reported efficacy were found (p < 0.05). Conclusion The 1-week use of DHM failed to show a predictable effect on discomfort during PMPR overall. Around 20% of the patients showed a quantifiable benefit from both test mouth-rinses, whereas more than 50% reported a subjective pain reduction. Focusing patients undergoing supportive periodontal therapy, quantifiable effects were found for both test groups. From a patient’s point of view, DHM might be a suitable adjunct to enhance procedural comfort, especially in patients with a history of periodontitis. Clinical relevance The 1-week use of the dentinal-hypersensitivity-reducing mouth-rinses prior to professional-mechanical-plaque-removal showed to be a suitable adjunct to enhance procedural comfort during instrumentation, especially in patients undergoing supportive periodontal therapy. Registration number: DRKS00010811


1985 ◽  
Vol 5 (1) ◽  
pp. 24-26 ◽  
Author(s):  
Thomas A. Golper ◽  
David L. Sewell ◽  
Linda West ◽  
Marge Trinklein

Thirty routine CAPD exchange spikes (Travenol) were dipped in a Staphylococcus aureus suspension and then divided into three equal groups. Group I (G1) spikes were advanced from the bacterial suspension to a povidone-iodine solution for a five-minute soak; Group 2 (G2) spikes were advanced into a sterile, non-bacteriostatic, physiologic saline solution for a five-minute soak. Then G1 and G2 spikes were attached in the usual sterile fashion to dialysis bags pretreated with tryptic soy broth to enhance bacterial growth. Group 3 (G3) spikes were advanced immediately to pretreated dialysate bags. Cultures of the dialysis solution were obtained immediately after the spikes were connected to the dialysis bags, 48 hours later, and at weekly intervals for three weeks. All 10 of the G3 bags connected to spikes without soaking grew greater than 10 colony forming units/mi of S. aureus by 48 hours. All 10 of the saline soaked G2 bags also demonstrated growth at 48 hours. Only one of the 10 Gl povidone-iodine soaked spike bags grew detectable colonies of bacteria at 48 hours. We conclude that a five-minute povidone-iodine soaking of spikes contaminated with S. aureus usually will prevent bacterial growth but is not a perfect solution to the problems of spike contamination. The frequent occurrence of peritonitis remains the limiting factor to the widespread acceptance of CAPD. Oreopoulos et al proposed that 36.5% of episodes of peritonitis are secondary to contaminations at the connection site during the a CAPD bag exchange (1). Although the exact frequency is unknown, we agree that the likelihood is high that contamination at the time of the exchange is a common mode of bacterial access to the peritoneal cavity. When we established our CAPD programs we instructed our patients to change the tubing if the spike became contaminated. Patients only rarely notified us of this necessity, despite our suspicion that known contamination was occurring. Two of us asked the Bulletin's editors if one could manage spike contamination simply by soaking the spike in povidone-iodine (2). Vas recommended that the tubing be changed because simple soaking would not deal with contamination inside the lumen (3). We decided to study this issue further because we believed that patients would not comply with this recommendation.


2021 ◽  
Vol 10 (22) ◽  
pp. 1645-1649
Author(s):  
Pallavi Samatha Yalamanchili ◽  
Nirupa Elisetti ◽  
Janaki Kesipeddy ◽  
Bilwa Bindu A ◽  
Bhagyasree Vegunta

BACKGROUND The focus of this study was to assess the relationship of nutrients (magnesium, iron) in periodontitis and diabetic patients. Serum magnesium (Mg) and iron (Fe) levels were evaluated in periodontitis patients and were compared between diabetic patients with periodontitis and healthy controls. METHODS Total sixty subjects (18 females and 42 males) were recruited in this cross-sectional study and were divided into three groups - Group I (healthy subjects), Group II (chronic generalized periodontitis), Group III (Type II diabetes mellitus and chronic generalized periodontitis). Loe and Silness gingival index and probing pocket depth were used for categorizing chronic generalized periodontitis patients. Serum levels of magnesium and iron were estimated and then compared among the groups. Statistical analysis was done using one-way analysis of variance (ANOVA) and Newmann-Keuls multiple post-hoc procedures. Statistical significance was accepted for P ≤ 0.05. RESULTS Mean serum levels of magnesium (Mg) were 0.89 in Group 3 (Type II DM + CGP), 1.01 in Group 2 (CGP) against 1.52 in Group 1 (Control), which were statistically significant. Mean Iron (Fe) levels showed 165.56 in Group 3 (Type II DM + CGP), 137.77 in Group 2 (CGP) against 78.17 (Control) which is also statistically significant. CONCLUSIONS In this study, we found statistically significant decrease in magnesium and increase in serum iron levels in Group 3 (Type II DM + CGP) compared to Group 2 (CGP) and healthy controls. These findings suggest that trace elements also play an important role in the progression of periodontal disease. KEY WORDS Chronic Periodontitis, Diabetes Mellitus, Iron, Magnesium


Author(s):  
K. Vadivelan ◽  
J. S. Poyyamozhi ◽  
G. Dinesh Kumar ◽  
C. Rajan Rushender

Background: Low back pain is the common symptom of the lumbar region that more than 80 percent of people experience in their lifetime. Methods: Quasi-experimental study was conducted with three intervention groups. Ankle mobilization (Group I), Active stretching of calf muscle (Group 2), No Intervention (Group 3). This study was carried out in the Department of Physiotherapy at SRM University, Chennai. 21 subjects were included in the study, with 7 subjects in each group. Results: Median age was found to be 20 (19–21), 19 (18–20) and 21 (20–22) in group 1, group 2 and group 3 respectively and no significant difference was seen between the groups, p value 0.11) There was a significant improvement seen in visual analogue scale, in both the intervention groups before and after intervention. The median and IQR for ankle mobilization group pre and post intervention was 6 (IQR, 5–6) and 4 (IQR, 3–5) respectively, with a p value <0.01. Conclusions: Overall results have shown that both the intervention groups have similar effects in reducing lower back pain and improving lumbar flexion, compared to the control group. 


1978 ◽  
Vol 64 (4) ◽  
pp. 407-418 ◽  
Author(s):  
Federico Bozzetti

Sixty-six patients with locally advanced or diffuse gastrointestinal cancer or suffering from major complications due to surgery or radiation therapy, were treated with continuous parenteral hyperalimentation at the Istituto Nazionale Tumori of Milan for a cumulative period of 2101 study-days. Patients were divided into 4 groups: Group 1, malnourished patients with advanced gastrointestinal malignancy; Group 2, patients with gastrointestinal fistulae due to simple surgical complications or to radiation injury of the bowel; Group 3, patients with major postoperative complications; Group i, surgical patients with gastric or colo-rectal carcinoma treated preoperatively. Mean infusional regime for the various groups included 42–56 Cal/kg/day and 1.5 to 2.4 g amino acid/kg/day, and the duration of the treatment ranged from 7 to 144 days. The results obtained show that protein calorie depletion of cancer patients may depend on malnutrition and that it can be reversed by parenteral nutrition, in patients, that are candidates for surgical treatment or those who qualify for chemotherapy and/or radiotherapy. Parenteral nutrition has a fundamental role in patients with fistulae, even if much attention must be paid to the external care of the fistula and the wound. In addition, nutritional support by intravenous feeding has proven essential for a successful outcome of patients with major postoperative complications. Preoperative protein repletion and central venous nutrition in patients who require gastrointestinal surgery represent a modern advance in the field of cancer surgery.


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