scholarly journals CLINICAL PROFILE AND OUTCOME OF CHILDREN ADMITTED WITH STATUS EPILEPTICS

Author(s):  
Sushil Kuamr Bakolia ◽  
Gajendra Kumar Verma ◽  
Dinesh Kumar Barolia

Background: Objective of this study was to study epidemiology and clinical profile of Status epilepticus Methods: Hospital based cross sectional study conducted on 50 children All children aged between 1 month to 12 years who at presentation or during the PICU stay had convulsive status epilepticus - defined as continuous seizure activity or recurrent seizure activity without regaining consciousness lasting for >5 min. Results: Among 50 children 56.00 % were in the age group were less than 5 years ,24 % were between 6-10 years ,20.00 % were above 10 yrs. The mean age group was 6.21±1.26 years. Incidence was higher in males (64%) when compared to females (36%). Generalized tonic clonic seizure were observed in 46 (92.00%) and partial seizure was noted in 4 (8%) of the children. About 36 (72%) of the children developed SE for the first time. Conclusion: Status epilepticus is one of the common neurological emergency which requires admission to PICU. In our study epilepsy is one of the most common causes of status epilepticus. Early and appropriate treatment with anticonvulsants and use of mechanical ventilation may improve the outcome. Keywords: Status epilepticus, mortality, clinical profile

2019 ◽  
Vol 6 (3) ◽  
pp. 159-164 ◽  
Author(s):  
Rajniti Prasad ◽  
◽  
Sujoy Saha ◽  
Ashish Verma ◽  
Om Prakash Mishra ◽  
...  

2003 ◽  
Vol 40 (140) ◽  
pp. 172-176 ◽  
Author(s):  
Sudha Agrawal ◽  
V K Garg ◽  
A Agarwalla ◽  
M Deb

A hospital based prospective cross sectional study was under taken over one-yearperiod from April 1998 to March 1999 to study the clinical profile and sexual behaviorin sexually transmitted diseases (STDs) patients at Dermatology and Venereology OPDat BPKIHS, Dharan, Nepal. A total of 105 patients giving history suggestive of STDswere studied. These patients were also enquired for their sexual behaviors. Therewere 85 males and 20 females; and the majority (55.2%) was in the age group of 21-30 years. Most of the patients (25.7%) were students followed by housewives (17.2%).service holders (13.3%), businessmen (13.3%), unemployed (9.5%) and fanners(8.5%).. Literates were 80%. Sixty-eight percent males and 90% females were married.Majority of the males contracted infection from CSW (58.8%). Females got theinfection from husbands and friends. More than 50% of male had multiple partnerswhereas in case of females it was only 5%. Homosexual and bisexual were 3.5% and4.7% respectively in males. Unprotected sexual contact was found in 94.1% of malesand 100% of females. Syphilis (30.5%) was the commonest type of STD followed bygonorrhea (14.3%), genital warts (14.3%), chancroid (6.7%), candidiasis (6.7%),herpes genitalis (5.7%), mixed infection (4.7%), donovanosis (2.8%), andLymphogranuloma venereum (0.9%). In homosexual and bisexual, only NGU andsyphilis were seen. STDs constituted 0.97% of all new dermatology patients. In spiteof high proportion of promiscuous sexual behavior, there was only one HIV positivepatient.Key Words: Clinical profile, Sexual behavior, STD patients, Nepal.


2018 ◽  
Vol 5 (1) ◽  
pp. 202 ◽  
Author(s):  
Sreenivasulu T. ◽  
Jahnavi K.

Background: Dengue is the most common fever. Among all flavi-viruses, it is the most common. It can cause around 50-100 million infections. Every year 2-5 lakh cases of Dengue hemorrhagic fever occur. The objective of the research was to study clinical profile of patients with Dengue fever at a tertiary care hospital.Methods: Present study was cross sectional study. The patients were interviewed and examined at one point of time and later they were never followed which is similar to the cross-sectional study design. Present study was carried out in the hospital. This was done in the department of General Medicine of a tertiary care hospital. Present study was carried out over a period of one year.Results: In the present study, there were 78 males and 22 females. The sex ratio was 3.5:1. Maximum number of males (29.5%) was in the age group of 15-25. Among females, the maximum (40.9%) were in the age group of 26-35 years and 46-55 years (9%). The most common presenting symptom was fever in all cases followed by headache in 90%. Among bleeding manifestations, epistaxis, gum bleeding and hematuria (15%) were the common symptoms. Most patients presented with generalized lymphadenopathy in 52%. 56 patients showed only hepatomegaly and 46 splenomegaly, and 30 patients showed hepato splenomegaly. 99 showed leucopenia and 10 were anemic and 25 showed platelet count less than 1,50,000cells/cumm.Conclusions: Males were commonly affected. Younger age group of 15-25 was most commonly affected and fever and headache were the most common presenting symptoms. These findings help physicians in early diagnosis of dengue by suspecting these features as of dengue and can prevent morbidity and mortality associated with dengue.


Perfusion ◽  
2020 ◽  
pp. 026765912094315
Author(s):  
Yuan Li ◽  
Qingchen Wu ◽  
Haoming Shi ◽  
Dan Chen ◽  
Cheng Zhang

Introduction: Generalized convulsive status epilepticus is defined as a generalized and convulsive seizure with 5 minutes or more of continuous clinical and/or electrographic seizure activity or recurrent seizure activity without recovery between seizures. For the first time, we present a case with retrograde type A aortic dissection after endovascular repairment and received thoracotomy intensely. Case report: The patient experienced frequent generalized seizures in the immediate postoperative period, and status epilepticus was considered for his medical history, clinic symptoms and related examinations. Discussion and Conclusion: Generalized convulsive status epilepticus should be alert for avoiding delay in the rehabilitation particularly after aortic dissection surgery. Under the good condition of ventilation, combining morphine with midazolam or diazepam can more effectively relieve the symptoms.


2020 ◽  
Vol 15 (1) ◽  
pp. 50-54
Author(s):  
Sapna Chauhan ◽  
Krishnapriya Radhakrishnan

Aims: To study the association of clinical profile of patients with Abnormal Uterine Bleeding with the different endometrial histopathological patterns Methods: A retrospective cross-sectional study was done in the department of Obstetrics and Gynaecology at a hospital in Karnataka, India from January 2017 to January 2019. Medical records were reviewed for all the cases of abnormal uterine bleeding who underwent endometrial biopsy. Results: There were 148 records of endometrial biopsies; >55% were in 41-50 years age group; 28% had postmenopausal bleeding; and 28% presented with menorrhagia. Menorrhagia and menometrorrhagia were equally common under 50 years of age. The various physiological patterns of endometrium (proliferative, secretory & menstruating endometrium) were noted in more than half the cases (51%). Proliferative endometrium was in 37%, followed by hyperplasia without atypia in 22% and only 3% showed malignancy; all of whom were in the postmenopausal group. Even in women with post menopausal bleeding, proliferative pattern was the commonest (33%), followed by atrophic endometrium and malignancy. Atypical hyperplasia was found to be most commonly associated with post menopausal bleeding. Conclusions: Both physiological and non physiological endometrial patterns were seen almost equally among the AUB cases. The knowledge of endometrial pattern in a case of AUB helps to decide a plan of management. Endometrial sampling plays a very important role in management of AUB, especially in the age group of more than 40 yrs; i.e, the peri and post-menopausal age groups, where incidence of malignant or pre malignant conditions was noted to be the highest. Key words: abnormal uterine bleeding, endometrial cancer, endometrial sampling, hyperplasia


Author(s):  
Pankaj Jain ◽  
Om Prakash Meena ◽  
Shivcharan Jelia

Background: Dengue, an endemic disease in most subtropical and tropical regions of the world and it causes severe epidemics in India. Dengue is one of the most common acute viral illness associated with considerable morbidity and mortality. The objective of this study was to study laboratory findings and clinical profile of patients with dengue fever at a tertiary care hospital of coaching city Kota.Methods: This study was cross sectional study. The patients were examined at one point of time and later they were never followed which is similar to the cross-sectional study design. A total of 100 patients of dengue fever who were NS1 Antigen or IgM dengue positive, admitted to department of medicine of government medical college, Kota included in the study. Through clinical examination and relevant laboratory investigations performed in all patients.Results: In the present study, there were 74 males and 26 females. The sex ratio was 2.8:1. Maximum number of males (50%) was in the age group of 15-25 Years. Among females the maximum (42.3%) were in the age group of 15-25 years. The most common presenting symptom was fever in all cases followed by headache in 96%. Among bleeding manifestation, Epistaxis, gum bleeding and melena (24%) were the common symptom. 47% patients showed hepatomegaly and 38% showed splenomegaly. 12% patients were anemic and 51% showed leucopenia while 93% showed thrombocytopenia.Conclusions: Males were commonly affected. Young age group of 15-25 was more commonly affected. Fever and headache were the most common presenting symptom. As dengue causes increased morbidity and mortality and requires prompt diagnosis and treatment for the proper management of these cases, this study helps physicians in early diagnosis of dengue by suspecting the features as of dengue and can prevent morbidity and mortality associated with dengue.


2019 ◽  
Vol 7 (1) ◽  
pp. 172
Author(s):  
J. Gopala Krishna ◽  
U. Kishan

Background: Comorbidities and complications are more in patients with hypothyroidism compared to other people. hence early diagnosis and early treatment for hypothyroidism can prevent a lot of complications in patients with hypothyroidism and this is very true for subclinical hypothyroidism. Objective was to study the clinical profile of patients with hypothyroidism.Methods: A hospital based cross sectional study was carried out among 40 clinically diagnosed and biochemically confirmed hypothyroid cases of age group 21-60 years of age. Detailed clinical history was taken to note down the presenting symptoms. Thorough clinical examination was done to ascertain the clinical features and confirm. Data was analyzed using proportions.Results: The mean age of males was slightly more than females 36.8 years vs. 35.13 years. Total number of male patients was much lower i.e. only 10(25%) compared to 30(75%) female patients. The most common age group affected in either sexes was 31-40 years followed by 21-30 years. Among all the symptoms with which the patients presented, the most common symptom was weight gain which was seen in 29(72.5%) of the cases. The most common presenting sign was BMI >25 kg/m2 in 27 cases i.e. 67.5% of the cases followed by dry skin in 25 cases i.e. 62.5%.Conclusions: Any patient presenting with weight gain, lethargy, dry skin, hoarseness, dyspnoea, constipation, cold intolerance, depression, menstrual abnormalities, overweight, obesity, bradycardia, non-pitting edema, hypertension, pallor should be suspected of hypothyroidism and thyroid profile should be done to rule hypothyroidism.


2019 ◽  
Vol 19 (1) ◽  
pp. 29-34
Author(s):  
Andi Airina Binti A Agus ◽  
Dominicus Husada ◽  
Pudji Lestari

Abstract. Background Diphtheria is a vaccine-preventable disease and is eradicated mostly in developed countries. But the prevalence of diphtheria cases still remains endemic in developing countries such as Indonesia, mainly in East Java. Purpose: To study the clinical profile and epidemiological aspects of diphtheria cases admitted in Ruang Isolasi Khusus RSUD Dr. Soetomo in 2015. Method: This research is a hospital-based, cross-sectional study. The samples are all patients admitted in Ruang Isolasi Khusus RSUD Dr Soetomo with the diagnosis of diphtheria in 2015. Results: There were 23 diphtheria cases reported in Ruang Isolasi Khusus RSUD Dr. Soetomo in 2015. The most prevalent age group was 6 until 10 years old (56.52%) and the most common gender was male (57%). Most of the patients came from a non-endemic area (82.61%) and most of them are not fully vaccinated (73.91%). There are more unknowledgeable mothers (91%) about DPT immunization. The most prevalent clinical manifestations are fever, dysphagia and pseudomembrane (100%). Tonsillar diphtheria (86.96%) was the most prevalent type of diphtheria presented. There were no complications and mortality reported and the main managements used were isolation (100%), antibiotics (100%) and anti diphteria serum (82.61%). Conclusion: There is an age shift in the occurrence of diphtheria to 6 until 10 years of age. The immunization coverage especially the booster dose is still low among the patients. Less knowledge about DPT immunization contributes to low childhood immunization coverage. No complications and mortality reported.


2012 ◽  
Vol 45 (1) ◽  
pp. 89-94 ◽  
Author(s):  
Rita da Graça Carvalhal Frazão Corrêa ◽  
Dorlene Maria Cardoso de Aquino ◽  
Arlene de Jesus Mendes Caldas ◽  
Dayse Karen Carneiro Rêgo Amaral ◽  
Fábio Silva França ◽  
...  

INTRODUCTION: Leprosy is an infectious disease caused by Mycobacterium leprae. The aim of this study was to describe the epidemiological, clinical, and operational aspects of leprosy carriers. METHODS: A cross-sectional study leprosy patients assisted in São Luis, MA, was performed. RESULTS: Of the 85 cases analyzed, 51.7% were male participants, and 60% were brown. Concerning the age, 54.8% of women were between 35 and 49 years, and 57.6% of men were between 20 and 34 years. Lepromatous leprosy was found in 42.3% of cases, and the multibacillary form was found in 72.9%. The skin smear was positive in 42.3%. The occurrence of reaction was found in 43.5% of cases, and 83.5% had no Bacillus Calmette-Guérin scar. Leprosy in the family was reported by 44.7% of the patients. Most of the individuals (96.4%) lived in houses made of brick with more than three rooms (72.6%) and two persons per room (65.1%). Concerning the level of education, 41.4% of women and 34.1% of men had more than one to three years of education. The most evaluated age group in the beginning of the treatment was that of 35 to 49 years with a Grade 0 incapability (64.5%), and that in the end was the age group of 20 to 34 (29.9%) with Grade 0, 30.7% Grade 1, and 11.5% Grade 2. CONCLUSIONS: The frequency of multibacillary forms found in this study and the cases in family members point out delayed diagnoses. Thus, early diagnosis and appropriate treatment are important in decreasing the outcome of disabilities.


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