ANTIHYPERLIPIDEMIC ACTIVITY OF METHANOLIC EXTRACT OF AZADIRACHTA INDICA

2019 ◽  
Vol 8 (6) ◽  
Author(s):  
Shalu Baghel ◽  
Charanjeet Singh
Keyword(s):  
Azadirachta Indica ◽  
Room Temperature ◽  
Fine Powder ◽  
Atherogenic Diet ◽  
Hot Water ◽  
Constant Weight ◽  
Hot Air ◽  
Whole Plant ◽  
Antihyperlipidemic Activity ◽  
Defective Clearance

Hyperlipidemia often results from delayed or defective clearance, or overproduction of VLDL by the liver, which is subsequently transformed into LDL. The whole plant of Azadirachta indica was collected from local areas of Jaipur district areas of Rajasthan. The plant is authenticated by university of rajasthan by Drmanju Sharma dept of botany   Selected medicinal plant were cut into small pieces, cleaned and shade dried at room temperature then subjected to physical evaluation with different parameters. Macerated 5 g of air dried drug coarsely powdered with 100 ml of ethanol of the specified strength in a closed flask for twenty four hours, shaking frequently during six hours and allowed to stand for 18 h. About 2-3 g of powder is accurately weighed in a china dish and kept in hot air oven maintained at 110±1oC for four hours. After cooling in a desiccator, the loss in weight was recorded. This procedure was repeated till constant weight was obtained. For insoluble ash value Boiled the ash for 5-10 minutes with 25 ml of diluted hydrochloric acid, collected the insoluble matter in a Gooch crucible washed with hot water, ignited and weighed. Whole plant of Azadirachtaindicawas reduced to fine powder and was subjected to maceration in a 1 liter conical flask for 7 days at room temperature with alcohol (70%) water (30%). In the present study we aimed to screen various extracts of selected plants on Cholesterol induced hyperlipidemic rat model. Thus the results of the present investigation clearly indicated that the selected medicinal plants possess good antihyerlipidemic activity in atherogenic diet induced hyperlipidemic rats and led to the development of new Herbal formulation possessing antihyperlipidemic and antiatherosclerotic activities. This is the first study which investigates the hypolipidemic activity. Keywords: Azadirachta indica, antihyperlipidemic, antiatherosclerotic activities, Maceration.

The Water Content of Some Normal and Pathological Brains

1917 ◽  
Vol 63 (260) ◽  
pp. 98-100
Author(s):  
John Cruickshank
Keyword(s):  
White Matter ◽  
Room Temperature ◽  
Preceding Paper ◽  
Solid Material ◽  
Chemical Methods ◽  
Constant Weight ◽  
Hot Air ◽  
The Brain ◽  
A Current ◽  
Routine Measure

In the preceding paper it has been shown that the general or local atrophy of the brain occurring in chronic insanity is very largely due to loss of white matter. It seemed to be of interest to determine what chemical changes accompanied this shrinkage in the size of the brain. As a preliminary to an examination of the complex substances of which brain matter is composed, it was necessary to investigate the proportion of water to solids, as the figures obtained in this way are of the highest importance in regard to the interpretation of the results obtained by chemical methods. The examination of the various portions of brain tissue for the amount of water was therefore proceeded with as a routine measure. The whole of the grey or of the white matter, as the case might be, from each of the five portions, obtained as described in the preceding paper, was spread on glass plates in as thin a layer as possible and carefully weighed. The plates were then placed in a Hearson electric drying oven, the temperature of which was maintained at about 90° C. A current of dry hot air was passed into the oven from a fan attached to a small motor. After fifteen to twenty hours' exposure the plates were removed from the oven, and the solid material which remained was carefully and completely scraped off. It was then allowed to cool to room temperature and weighed. The material was returned to the oven for some hours, again removed and allowed to cool. This procedure was continued until the material attained a constant weight at room temperature. The percentage of water in each sample was then calculated.

scholarly journals Effects of Etlingera elatior inflorescence extract on beneficial bacteria of the healthy human gut

2021 ◽  
Vol 8 (2) ◽  
pp. 55-59
Author(s):  
Kavithra
Keyword(s):  
Fine Powder ◽  
Peninsular Malaysia ◽  
Hot Water ◽  
Beneficial Bacteria ◽  
Human Gut ◽  
Healthy Human ◽  
Hot Water Extraction ◽  
Hot Air ◽  
Broth Dilution ◽  
Etlingera Elatior

Background: Etlingera species is an enduring plant in the Zingiberaceae family, with more than 100 species local to many countries. It has been utilized commonly as a culinary spice or eaten crude for its therapeutic impacts. This research is intended to study the effects of E. elatior inflorescence, which is commonly known as bunga kantan in Peninsular Malaysia, upon the microbiota of healthy human gut. Material and methods: The closed bud E. elatior inflorescence was cleaned and dried in the hot air oven and grounded into fine powder. The extract from the E. elatior inflorescence was obtained using hot water extraction method. The effects of the inflorescence extract on L. rhamnosus and L. acidophilus were studied through micro-broth dilution process where different concentration of sample was incorporated into a broth medium followed by the application of a standardized volume of Lactobacillus sp. into the medium of the 96 well plate. Results: Growth was seen in both L. rhamnosus and L. acidophilus, indicating that E. elatior inflorescence acted like a prebiotic towards L. acidophilus and L. rhamnosus Conclusion: E. elatior inflorescence concentrate acts like a prebiotic towards L. acidophilus incomparable to L. rhamnosus

DETERMINING THE PROFITABILITY OF GREENHOUSE ELECTROTECHNOLOGIES: A MODELING APPROACH

HortScience ◽  
1994 ◽  
Vol 29 (4) ◽  
pp. 249a-249
Author(s):  
Eric A. Lavoie ◽  
Damien de Halleux ◽  
André Gosselin ◽  
Jean-Claude Dufour
Keyword(s):  
Energy Consumption ◽  
Heat Pump ◽  
Water System ◽  
Heat Pumps ◽  
Hot Water ◽  
Pump System ◽  
Heat Pump System ◽  
Artificial Lighting ◽  
Hot Air ◽  
Marketable Fruit

The main objective of this research was to produce a simulated model that permitted the evaluation of operating costs of commercial greenhouse tomato growers with respect to heating methods (hot air, hot water, radiant and heat pumps) and the use of artificial lighting for 1991 and 1992. This research showed that the main factors that negatively influence profitability were energy consumption during cold periods and the price of tomatoes during the summer season. The conventional hot water system consumed less energy than the heat pump system and produced marketable fruit yields similar to those from the heat pump system. The hot water system was generally more profitable in regards to energy consumption and productivity. Moreover, investment costs were less; therefore, this system gives best overall financial savings. As for radiant and hot air systems, their overall financial status falls between that of the hot water system and the heat pump. The radiant system proved to be more energy efficient that the hot air system, but the latter produced a higher marketable fruit yield over the 2-year study.

Matrix metalloproteinase-2 inhibition activity of Plukenetia volubilis L. leaves extract for anti-aging application

Food Research ◽  
2021 ◽  
Vol 5 (4) ◽  
pp. 120-126
Author(s):  
N. Wuttisin ◽  
T. Nararatwanchai ◽  
A. Sarikaphuti
Keyword(s):  
High Performance ◽  
Antioxidant Property ◽  
In Vitro Cytotoxicity ◽  
Hot Water ◽  
Matrix Metalloproteinase 2 ◽  
Human Skin Fibroblast ◽  
Inhibition Activity ◽  
Hot Air ◽  
Plukenetia Volubilis

Plukenetia volubilis L. leaves were part of the traditional diets in many countries. P. volubilis leaves were used to make tea and sold as local products in Thailand. There is less information on the composition of P. volubilis leaves. Previous study revealed that roasted leaves extract with hot water showed the highest antioxidant activity and the antioxidant property might be due to the presence of flavonoid. The present study was carried out to determine the quercetin content in P. volubilis leaves extract and evaluate the anti-aging potential activities including MMP-2 inhibition activity and telomerase stimulation activity. P. volubilis leaves were roasted in hot air oven and extracted with hot water. The extract was investigated for quercetin content by high-performance liquid chromatography (HPLC). In vitro cytotoxicity, MMP-2 inhibition activity and telomerase stimulation activity were determined for anti-aging properties. The results revealed that P. volubilis leaves contained quercetin 50.50±4.78 mg/g DW. The extract showed no cytotoxicity on human skin fibroblast with cell viability of 96.76-120.83%. It demonstrated the potential of MMP-2 inhibition (8.74±2.84%) activity but lower than ascorbic acid. P. volubilis leave extract did not have telomerase stimulation activity on the human Hela cell line. However, the results from this study have indicated the possibility of anti-aging potential of P. volubilis leaves extract.

scholarly journals Effect of Blanching and Drying Temperatures on Physicochemical Properties of Red Dragon Fruit (Hylocereus polyrhizus) Peel Powder

2021 ◽  
Vol 12 (1S) ◽  
pp. 62-73
Author(s):  
Nor Anis Shafira Rosidi ◽  
Asmaliza Abdul Ghani @ Yaacob ◽  
Nurhayati Yusof ◽  
Norzaida Yusof
Keyword(s):  
Physicochemical Properties ◽  
Water Solubility ◽  
Hot Water ◽  
Powdered Sample ◽  
Fruit Peel ◽  
Hot Air ◽  
Dragon Fruit ◽  
Large Production ◽  
Range Of Values ◽  
By Products

Large production of red dragon fruit by-products, which are frequently discarded from food industry has become a major waste problem. Converting this waste into useful products with good physicochemical properties could solve the pollution issues. Thus, a study was carried out to investigate the effect of blanching and drying temperatures on physicochemical properties of red dragon fruit peel powder. Dragon fruit peel was pre-treated with hot water at 90 °C for 2 minutes before being dried in hot air oven dryer at 50 °C, 60 °C and 70 °C. Results showed that the powdered sample of blanched and dried at 50 °C had significantly higher fiber, water activity and moisture content than those of unblanched/blanched and dried at 60 °C and 70 °C. Result also showed that the colour of this powder was similar to the fresh dragon fruit peel. When dried at 50 °C, the unblanched and blanched powders exhibited a slightly higher water solubility index compared to those dried at 60 °C and 70 °C. Based on the evaluation of bulk and tapped densities, all powders having the Carr Index in the range of values between 20 and 28 thus can be categorised as slightly poor flowing. For all conditions studied, powder that was blanched and dried at 50 °C was the best condition as it contained the highest amount of fiber with good physicochemical properties.

scholarly journals Study on Sewage Sludge Drying System With Built-in Solar Drying Bed

2021 ◽  
Vol 237 ◽  
pp. 01041
Author(s):  
Zhipan Gu ◽  
Jichun Yang ◽  
Jing Liu ◽  
Leren Tao ◽  
Ye Zhang ◽  
...  
Keyword(s):  
Heat Transfer ◽  
Sewage Sludge ◽  
Radiation Heat Transfer ◽  
Middle Layer ◽  
Bottom Layer ◽  
Mass Transfer Process ◽  
Hot Water ◽  
Solar Drying ◽  
Hot Air ◽  
Air Supply

In this paper, the renewable energy solar energy is used as the heat source. The combination of solar drying bed and traditional hot air drying can effectively reduce energy consumption and operation cost. The drying chamber is divided into three layers. The top air supply outlet supplies hot air, the middle layer places wet sludge, and the bottom layer uses hot water coil to dry the sludge. The whole drying process is a heat and mass transfer process with convective heat transfer and radiation heat transfer. After analysis and comparison with traditional energy drying, it is found that drying 97.5kg of sewage sludge will save 79% energy, save 12.84 kg of standard coal, reduce 32 kg of carbon dioxide and 1.284 kg of sulphur dioxide.

scholarly journals Effect of pre-sowing treatments and growing media on seed germination and seedling growth of Albizia lebbeck (L.) Benth

2018 ◽  
Vol 10 (3) ◽  
pp. 860-863
Author(s):  
Naresh Kumar ◽  
A. K. Handa ◽  
Inder Dev ◽  
Asha Ram ◽  
A. R. Uthappa ◽  
...  
Keyword(s):  
Seedling Growth ◽  
Room Temperature ◽  
Cold Water ◽  
Hot Water ◽  
Albizia Lebbeck ◽  
Physical Dormancy ◽  
Growing Media ◽  
Hard Seed ◽  
Collar Diameter ◽  
Hard Seed Coat

The seeds of Albizia lebbeck have been observed to exhibit physical dormancy due to presence of hard seed-coat. To overcome this problem, the seeds were subjected to seven pre-sowing treatments viz., T1-immersion of seeds in cold water for 12 h; T2-immersion of seeds in cold water for 24 h; T3-immersion of seeds in hot water (100 °C) and subsequent cooling at room temperature for 12 h; T4-immersion of seeds in hot water (100 °C) and subsequent cooling at room temperature for 24 h; T5-immersion of seeds in cold water for 12 h followed by immersion in hot water (100 °C) and allowed to cool for 1 h; T6-immersion of seeds in cold water for 24 h followed by immersion in hot water (100 °C) and allowed to cool for 1 h. Untreated seeds served as control (T0). Treatment T3 gave highest germination (96%) which was comparable with T5 (95 %), T4 (94 %) and T6 (93%). Nine growing media viz., T1: soil,  T2: soil+sand (2:1), T3: soil+perlite (2:1), T4: soil+Farm Yard Manure (FYM) (2:1), T5: soil+vermicompost (2:1), T6: soil+sand+FYM (1:1:1), T7: soil+sand+vermicompost (1:1:1), T8: soil+perlite+FYM (1:1:1) and T9: soil+perlite+ vermicompost (1:1:1) were, also, studied for their effect on seedling growth of A. lebbeck. Among these media, maximum values of shoot length (23.82 cm), root length (21.14 cm), collar diameter (3.59 mm) and seedling quality index (0.350) were observed in T7.

scholarly journals COMPARISION OF ANTIOXIDANT ACTIVITY OF ACTINIDIA DELICIOSA AND PSIDIUM GUAJAVA USING FERRIC REDUCING ANTIOXIDANT POWER ASSAY METHOD

2020 ◽  
pp. 175-178
Author(s):  
CAROLINE JEBA R ◽  
INDHUJA D
Keyword(s):  
Antioxidant Activity ◽  
Room Temperature ◽  
Psidium Guajava ◽  
Actinidia Deliciosa ◽  
Assay Method ◽  
Frap Assay ◽  
Antioxidant Power ◽  
Hot Air ◽  
Ferric Reducing Antioxidant Power ◽  
Dried Extract

Objectives: Antioxidant activity was studied in naturally dried seed extract and hot air oven dried extract of Actinidia deliciosa and Psidium guajava using ferric reducing antioxidant power (FRAP) assay method. Methods: The dried powdered seed of A. deliciosa and P. guajava 10 g was dissolved in 100 ml of ethanol in four different conical flasks S1 (for naturaly dried seeds of A. deliciosa), S2 (for hot air oven-dried seeds of A. deliciosa), S3 (for naturally dried seeds of P. guajava), and S4 (for hot air oven-dried seeds of P. guajava). The extract was carried out in shaker at 120 rpm for 72 h at room temperature by mild shaking. The extract was taken out and centrifuged at 4000 rpm for 10 min, the supernatant was taken out. The supernatant was placed in a water bath at 95°C for the solvent to evaporate and stored at room temperature. Results: According to the FRAP results, P. guajava which was naturally dried and extracted has shown the highest antioxidant activity (sample 3) then followed by the samples S4, S1, and S2. The least activity is observed in the sample (S2). Conclusion: By comparing the antioxidant activity between the A. deliciosa and P. guajava with the help of FRAP assay results, P. guajava has the highest amount of vitamin C (responsible for antioxidant activity) when compared to that of the A. deliciosa.

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