scholarly journals Hubungan kadar leptin serum dengan derajat rinitis alergi

2011 ◽  
Vol 41 (1) ◽  
pp. 30
Author(s):  
Ahmad Dian Wahyudiono ◽  
Endang Retnoningsih ◽  
Pudji Rahaju

Background: Allergic rhinitis is a global health problem that could impair the patient’s quality of life. Recent studies had showed the role of leptin, a hormone that produced by adipose tissue, on sensitization process which can increase the serum level of B cells and IgE. Purpose: To define the relationship between serum leptin level with the degree of allergic rhinitis based on ARIA and VAS.Methods: This study involved 38 subjects with cross sectional design. Statistical analysis included t-test, logistic regression and Kruskal-Wallis. Results: This study showed serum leptin level has correlation with the degree of allergic rhinitis based on ARIA (p<0.05), specifically on the intensity of allergic rhinitis (p<0.05), but not with the degree of allergic rhinitis based on VAS. Conclusion: Serum leptin level has a role on the degree of allergic rhinitis specifically on the intensity but not on the severity of allergic rhinitis symptoms. Controlling the serum leptin level can be considered as health promotion for patient with allergic rhinitis. Further research focusing on controlling serum leptin level for allergic rhinitis symptoms is recommended. Keywords: allergic rhinitis, serum leptin level, degree of allergic rhinitis   Abstrak :  Latar belakang: Rinitis alergi merupakan masalah kesehatan global dan dapat mengganggu kualitas hidup penderitanya. Beberapa penelitian telah menunjukkan peran leptin, hormon yang diproduksi oleh jaringan lemak, pada proses sensitisasi yang ditandai dengan kemampuan leptin meningkatkan sel B dan IgE. Tujuan: Penelitian ini bertujuan mengetahui hubungan kadar leptin serum dengan derajat rinitis alergi. Metode: Penelitian ini melibatkan 38 subjek dengan desain potong lintang untuk mengetahui hubungan kadar leptin serum dengan derajat rinitis alergi pada penderita rinitis alergi. Analisis statistik yang digunakan adalah uji t, uji regresi dan Kruskal-Wallis.Hasil: Penelitian ini menunjukkan bahwa kadar leptin serum berhubungan dengan derajat rinitis alergi berdasarkan ARIA (p<0,05) khususnya dengan intensitas keluhannya (p<0,05), namun tidak berhubungan dengan derajat rinitis berdasarkan VAS. Kesimpulan: Kadar leptin serum berhubungan dengan derajat rinitis alergi terutama pada intensitas keluhan dan bukan pada beratnya keluhan. Pengendalian kadar leptin serum dapat dipertimbangkan sebagai upaya memperbaiki kesehatan penderita rinitis alergi. Penelitian lebih lanjut yang menekankan pada pengendalian kadar serum leptin disarankan untuk mengendalikan keluhan rinitis alergi. Kata kunci: rinitis alergi, kadar leptin serum, derajat rinitis alergi

Author(s):  
Etik Pratiwi ◽  
Sri Mulatsih ◽  
Sri Setiyarini

Background: In Indonesia, the prevalence of cancer up to 1.4 per 1000 population. Acute lymphocyte leukemia is one of type of cancers. Sspirituality is an element that increasing and is recognized by many patients with the disease at an advanced stage. Assessment of spirituality in children acute lymphocyte leukemia had ever done by the researcher before shows that spirituality contributes a positive influence to the coping and the achievement of adaptation. Aim of this research was to know how the relationship between spirituality with quality of life in children with cancer.Methods: This study used a mixed design (mixed method), with sequential explanatory strategy. Quantitative approach to the cross-sectional design and in- depth interviews in qualitative data collection. Research has received permission from the The Medical and Health Research Ethics Committee (MHREC).Results: There is a relationship between spirituality and the quality of life of children with cancer with a total value of p=0.001. Spirituality related to the children quality of life emotional, school, and physical domains with each value of p=0.001, p=0.026, p=0.028. Spirituality is not related to the social domains with p=0.054. Qualitative analysis shows that there are six categories from in-depth interviews, that is namely; prayer as a healing pain, the joy and gratitude; the interaction of the source of happiness; loneliness sadness source; socialitation with the enviroment; seek help in overcoming difficulties.Conclusions: There was correlation between spirituality and quality of life of children with cancer. 


Author(s):  
Ana Carolina Marian da Silva e Silva ◽  
Aline Arakawa-Belaunde

Objective: To verify the relationship between the quality of life and the socio-demographic and cognitive aspects of the participating elderly people from social groups. Methods: Epidemiological, quantitative, cross-sectional design study, carried out in groups of elderly people living in a capital city in southern Brazil. Four questionnaires were used concerning sociodemographic characterization, quality of life, cognitive aspects and subjective memory complaints. Results: There were significant differences in the quality of life and its domains in terms of age, education, income and region of residence, and cognitive aspects. The answers obtained in the general questions of the instrument showed that the quality of life was considered good by 176 (54.83%) of the respondents and 151 (47.04%) were considered satisfied in terms of overall health. Conclusion: Socio-demographic aspects, as well as cognitive aspects, are associated with the quality of life of active elderly people in the municipality. The complaint of subjective memory is emphasized, which showed a relationship with all the analyzed aspects of the quality of life. The data obtained can serve as inputs to expand the possibilities of promoting the health and quality of life of the elderly population.


2021 ◽  
Vol 38 ◽  
Author(s):  
Olayemi Fehintola Awopeju ◽  
Oluwasina Titus Salami ◽  
Adebola Adetiloye ◽  
Bamidele Olaiya Adeniyi ◽  
Olufemi Olanisun Adewole ◽  
...  

Author(s):  
Arif Wicaksono ◽  
Muhammad Sajidin

Hemodialysis therapy of patients with chronic kidney disease can changes the patients physically, psychological, social and economics because they have to deal with it for the rest of their life. This can affect the quality of life of the patients because of the long-term of hemodialysis therapy, this is one of the factors that affect the quality of life of the patients with chronic kidney disease. Quality of life is focused on the assessment of the individual against conditions acceptance. Each individual takes different phases to accept the condition. The purposes of the study were to determine if the relationship between the duration of hemodialysis and quality of life of the patients with chronic kidney disease at Gatoel Hospital Mojokerto. This research used cross-sectional design. The patient's population with chronic kidney disease undergoing hemodialysis is 150 people. The research sample is drawn using sampling techniques with the type of nonprobability purposive sampling with 130 people as a sample. Data obtained from questionnaires KDQoL 36. The result using Spearman rho test using SPSS V.16 shows p < α (0,006 < 0,05). H0 rejected, this means that there is a relationship between the duration of hemodialysis and quality of life with chronic kidney disease at Gatoel Hospital Mojokerto. The quality of life of the patients fluctuated based on the stage adaptation of the hemodialysis and disease. However, most patients with the duration of hemodialysis for more than 12 months had a sufficient quality of life and their therapy are already familiar with the symptoms and complications, but there are other factors that affect the quality of life such as gender, marital status, and education level. Patients are also expected to cooperate in what to do and not to do to improve the quality of life of the patients.


Author(s):  
Arif Wicaksono ◽  
Muhammad Sajidin

Hemodialysis therapy of patients with chronic kidney disease can changes the patients physically, psychological, social and economics because they have to deal with it for the rest of their life. This can affect the quality of life of the patients because of the long-term of hemodialysis therapy, this is one of the factors that affect the quality of life of the patients with chronic kidney disease. Quality of life is focused on the assessment of the individual against conditions acceptance. Each individual takes different phases to accept the condition. The purposes of the study were to determine if the relationship between the duration of hemodialysis and quality of life of the patients with chronic kidney disease at Gatoel Hospital Mojokerto. This research used cross-sectional design. The patient's population with chronic kidney disease undergoing hemodialysis is 150 people. The research sample is drawn using sampling techniques with the type of nonprobability purposive sampling with 130 people as a sample. Data obtained from questionnaires KDQoL 36. The result using Spearman rho test using SPSS V.16 shows p < α (0,006 < 0,05). H0 rejected, this means that there is a relationship between the duration of hemodialysis and quality of life with chronic kidney disease at Gatoel Hospital Mojokerto. The quality of life of the patients fluctuated based on the stage adaptation of the hemodialysis and disease. However, most patients with the duration of hemodialysis for more than 12 months had a sufficient quality of life and their therapy are already familiar with the symptoms and complications, but there are other factors that affect the quality of life such as gender, marital status, and education level. Patients are also expected to cooperate in what to do and not to do to improve the quality of life of the patients.


2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Sri Hendrawati ◽  
Ikeu Nurhidayah ◽  
Henny Suzana Mediani ◽  
Ai Mardhiyah ◽  
Nenden Nur Asriyani Maryam

Mucositis is very common in children with cancer who received chemotherapy. Mucositis in children renders other health problems such as pain, eating problems, insomnia, and emotional problems that directly determine children’s quality of life. The purpose of this research was to identify how the effects of mucositis on quality of life in children with cancer who received chemotherapy. The method used in this research is correlative descriptive analytic with cross-sectional design. Samples taken in this research utilized consecutive sampling technique. The children with cancer who met the inclusion criteria were approached to participate in this research. Sixty children with cancer hospitalized in Dr. Hasan Sadikin Hospital Bandung recruited in this research. Mucositis identification utilized Oral Assessment Guide (OAG). Data quality of life (QoL) would be assessed with PedsQoL Cancer Module 3.0. Data were analyzed by Chi-square correlation test. There are 53 children (88.3%) who experienced mucositis. In contrast, there are only 7 children who didn’t experience mucositis (11.7%). Based on this survey, there are 37 children (61.7%) have bad quality of life. Otherwise, 23 children (38.3%) have good quality of life. This research found that there is a significant relationship between mucositis and QoL of children with cancer. Accordingly, the relationship between mucositis cases and QoL of children with cancer valued at 0.006 (p<0.05). Mucositis cause low QoL in children with cancer compared to them without mucositis. Nurse should increase nursing care for children with mucositis as the side effect of chemotherapy. Suggested efforts are to prevent mucositis complication that will impact QoL, such as giving oral care with honey, keeping humid oral mucosa, and preventing infection


e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Moch. T. S. A. Rahman ◽  
Theresia M. D. Kaunang ◽  
Christofel Elim

Abstract: Chronic kidney disease (CKD) results in a decrease in kidney function that is irreversible and requires treatment in the form of a kidney transplant or hemodialysis. The main goal of hemodialysis is to prevent and control uremia, fluid overload, and electrolyte imbalance. Problems that commonly associate hemodialysis patients are physical and psycological stress that affect the quality of life. This study aimed to obtain the relationship between the duration of hemodialyis and the quality of life. This was an observational analytical study with a cross sectional design. The study included all hemodialysis patients in Dahlia and Melati Hemodialysis Unit Prof. Dr. R. D. Kandou Hospital Manado. There were 34 patients that met the inclusion criteria. The results showed that the correlation between the duration of hemodialyis and the quality of life had a p value of 0.579. Conclusion: The duration of hemodialysis did not correlate significantly with the quality of life of hemodialysis patients.Keywords: The duration of hemodialysis, quality of life.Abstrak: Gagal ginjal kronik (PJK) mengakibatkan penurunan fungsi ginjal yang ireversibel, yang memerlukan terapi berupa transplantasi ginjal atau hemodialisis. Tujuan utama hemodialisis yaitu mengendalikan uremia, kelebihan cairan dan ketidakseimbangan elektrolit. Permasalahan yang muncul pada pasien hemodialisis ialah masalah fisik, psikologi, perubahan sosial, dan gaya hidup; hal tersebut memengaruhi kualitas hidup pasien. Peneltian ini bertujuan untuk mencari hubungan antara lama menjalani hemodialisis dengan kualitas hidup. Metode penelitian yang digunakan ialah observasional analitik dengan pendekatan potong lintang Penelitian ini melibatkan semua pasien hemodialisis di Unit Hemodialisis Dahlia dan Melati RSUP Prof. Dr. R. D. Kandou Manado yang memenuhi kriteria inklusi yaitu sebanyak 34 orang. Hasil penelitian menunjukkan korelasi antara lama menjalani hemodialisis dengan kualitas hidup dengan nilai P=0,579. Simpulan: Tidak terdapat hubungan antara lama menjalani hemodialisis dengan kualitas hidup pada pasien hemodialisis.Kata kunci: lama menjalani hemodialisis, kualitas hidup.


2021 ◽  
Vol 3 (4) ◽  
pp. 609-616
Author(s):  
Dea Prasetya

ABSTRACT: THE RELATIONSHIP OF PRE-TRANSFUSION HB LEVEL WITH QUALITY OF LIFE OF THALASSEMIA PATIENTS IN RSUD Dr. Hi ABDUL MOELOEK, LAMPUNG PROVINCE Background: Thalassemia is a chronic disease that can significantly affect the patient's quality of life, which is caused by the disease itself and the effects of the therapy given. Patients with thalassemia in Dr. H Abdoel Moeloek Hospital Lampung Province from year to year showed an increasing trend, namely in 2012 as many as 75 people, in 2013 as many as 87 people, and in 2014 as many as 102 people.Purpose: To determine the relationship between Hb levels before transfusion with the quality of life of thalassemia patients. Hi Abdul Moeloek Lampung ProvinceResearch Methods: This type of research is a quantitative, analytical observation design, with a cross-sectional design. The study population was all pediatric thalassemia patients at Dr. Hospital. Hi Abdul Moeloek, Lampung Province for the period January – October 2019 with a total of 146 patients. The sample is 60 people. Collecting data using observation sheets and questionnaires. The data analysis technique used a regression test.Results: The average distribution of Hb levels before transfusion of the research subjects was 7.11 with the lowest value being 6.8 and the highest being 7.4. The distribution of the average quality of life of the subjects of this study was 60.72 with the lowest value of 27 and the highest 93. There was a significant relationship between pre-transfusion Hb Levels and Quality of Life of Thalassemia Patients at Abdul Moeloek Hospital Bandar Lampung in 2019 (p-value 0.000 ).Conclusion: There is a significant relationship between Hb levels before transfusion with Quality of Life of Thalassemia Patients. It is recommended to monitor Hb levels before transfusion and comply with transfusions and consume iron chelation regularly so that the growth of their children can be normal like other children. Keywords: Hb levels before transfusion, Quality of Life, Thalassemia Patients  INTISARI: HUBUNGAN KADAR HB PRE TRANFUSI DENGAN KUALITAS HIDUP PENDERITA TALASEMIA DI RSUD Dr. Hi ABDUL MOELOEK PROVINSI LAMPUNG  Latar Belakang : Thalasemia adalah salah satu penyakit  kronis  yang  dapat mempengaruhi kualitas hidup penderita secara nyata, yang diakibatkan penyakitnya sendiri maupun efek terapi yang diberikan. Penderita thalasemia di RSUD Dr H Abdoel Moeloek Provinsi Lampung, dari tahun ketahun menunjukkan trend mengalami kenaikan, yaitu tahun 2012 berjumlah 75 orang, tahun 2013 berjumlah 87 orang dan tahun 2014  tercatat  102  orang.Tujuan penelitian:  Diketahui  hubungan kadar Hb Pre Transfusi dengan kualitas hidup penderita Talasemia Di RSUD Dr. Hi Abdul Moeloek Provinsi LampungMetode Penelitian : Jenis penelitian kuantitatif, rancangan observasi analitik, dengan desain cross sectional. Populasi penelitian adalah semua pasien Talasemia anak di RSUD Dr. Hi Abdul Moeloek Provinsi Lampung periode Januari - Oktober 2019 sejumlah 146 pasien. Sampel 60 orang. Pengambilan data menggunakan lembar observasi dan kuesioner. Teknik analisis data menggunakan uji regresi.Hasil penelitian : Distribusi rata-rata kadar Hb Pre tranfusi subyek penelitian ini adalah 7,11 dengan nilai terendah 6,8 dan tertinggi 7.4. Distribusi rata-rata kualitas hidup subyek penelitian ini adalah 60,72 dengan nilai terendah 27 dan tertinggi 93. Ada hubungan antara hubungan yang signifikan antara Kadar Hb Pre Transfusi Dengan Kualitas Hidup Penderita Talasemia di Rumah Sakit Abdul Moeloek Bandar Lampung tahun 2019 (p value 0,000).Kesimpulan : Ada hubungan antara hubungan yang signifikan antara Kadar Hb Pre Transfusi Dengan Kualitas Hidup Penderita Talasemia. Disarankan agar melakukan pemantauan terhadap Kadar Hb Pre Transfusi dan patuh menjalani tranfusi serta mengkonsumsi kelasi besi secara teratur agar pertumbuhan anaknya dapat normal seperti anak-anak lainnya. Kata Kunci    : Kadar Hb Pre Transfusi, Kualitas Hidup, Penderita Talasemia


2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P29-P29
Author(s):  
Charles S. Coffey ◽  
Richard J. Harvey ◽  
Jamie I. Woody ◽  
Sarah K. Koepp ◽  
Patrick Sheahan ◽  
...  

Objective (1) Assess the relationship between QoL, objective assessment and confounding factors. (2) Describe a model representing the severity of pathology and predicting potential responses from therapeutic interventions beyond Quality of Life measurements alone. Methods A cross-sectional study of allergic rhinitis (AR) patients, from a teritary rhinology clinic in 2007, with Modified Quantitative Testing (MQT) and Mini-Rhinoconjuctivitis Quality of Life Questionnaire (mRQLQ) assessments was performed. Correlation and regression analyses assessed the relationship of mRQLQ, MQT endpoints, and number of reactive antigens. Results 47 patients (53% female, mean age 36.0 ± 16.3yrs) were assessed. Percentage of positive antigens was a significant factor that decreased mRQLQ (p=0.05). Maximal MQT endpoint (mMQT) correlates well to mRQLQ when controlled for percentage of positive antigens (p=0.038). In a regression analysis to predict mRQLQ, percentage of positive antigens and mMQT were good predictors (p=0.018 for percent positive antigens; p=0.038 for mMQT) and such a model was significantly linked to those factors (F=3.2, p=0.05). Conclusions Semi-quantitative measurement by MQT correlates with symptom severity in AR when broad reactivity does not exist. Adaptation in QoL scores may occur with more atopic individuals. A model for predicting QoL and symptom severity as measured by mRQLQ based upon MQT is presented. Such systems may enhance our ability to predict clinical outcomes, compare research cohorts, and better educate patients on treatment benefits.


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