scholarly journals Serum Adiponectin Level is Lower in Patients with Endometriotic Cyst

2016 ◽  
pp. 119-123
Author(s):  
Fahdiansyah Fahdiansyah ◽  
Ruswana Anwar ◽  
Setyorini Irianti
Keyword(s):  
Analytical Study ◽  
Obstet Gynecol ◽  
Adiponectin Level ◽  
Stage Iv ◽  
Serum Adiponectin ◽  
Serum Adiponectin Level ◽  
Cross Sectional ◽  
Significant Difference ◽  
Endometriotic Cyst ◽  
The Difference

Objectives: To analyse the difference of serum adiponectin level between patients with endometriotic cyst and those with non-endometriotic cyst, and its difference between endometriosis stages. Methods: This is a cross-sectional comparative analytical study involving 25 women with endometriotic cyst and 25 women with nonendometriotic cyst, which had undergone laparoscopy or laparotomy surgery. Blood samples were withdrawn and checked for serum adiponectin level in PRODIA laboratory in Jakarta. Serum adiponectin level of both groups were then measured and compared. The study was conducted in Dr. Hasan Sadikin Hospital in September- December 2012. Results: Shows no significant difference in subjects’ characteristic which are age (p = 0.994) and BMI (p = 0.267). There is a significant difference (p < 0.0001) between serum adiponectin level in endometriosis group (mean = 3.91 ± 1.976) with level of which in nonendometriosis group (mean = 8.59 ± 1.977). There is no significant difference (p = 0.384) of serum adiponectin level between stage III endometriosis (mean = 4.24 ± 1.8168) and stage IV endometriosis (mean = 3.54 ± 2.1531). Conclusion: Serum adiponectin level in patients with endometriotic cyst is significantly lower compared to level of which in patients with non-endometriotic cyst. There is no significant difference of serum adiponectin level between endometriosis stages. [Indones J Obstet Gynecol 2013; 1-3: 119-23] Keywords: adiponectin, endometriotic cyst, non-endometriotic cyst, endometriosis stage

scholarly journals Serum Adiponectin Level in Diabetic Patients with and withoutHelicobacter pyloriInfection: Is There Any Difference?

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Jamshid Vafaeimanesh ◽  
Akram Heidari ◽  
Marzieh Effatpanah ◽  
Mahmoud Parham
Keyword(s):  
Insulin Resistance ◽  
Adiponectin Level ◽  
Serum Levels ◽  
Serum Adiponectin ◽  
Diabetic Patients ◽  
Serum Adiponectin Level ◽  
Igg Antibody ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Mean

Background.Increased insulin resistance is an extragastrointestinal manifestation ofHelicobacter pylori(HP) infection. HP changes the level of inflammatory markers and cytokines and changes the adipocyte function by altering the adiponectin level. Given the high prevalence of HP and diabetes in our society, we evaluated the association between HP and serum adiponectin level. In this cross-sectional study, 211 diabetic patients under treatment other than insulin were studied. These patients were divided into two groups of HP+ and HP− based on their HP IgG antibody serology and their blood adiponectin levels were measured. Data was analyzed using independentt-test, Chi-square test, and Fisher’s exact test.Results.Seventy-two patients with an average age of51.56±8.34years were HP− and 139 patients with an average age of50.35±9.01years were HP+. The mean serum adiponectin level in HP− and HP+ groups was4.54±5.43and5.64±3.88 ng/mL, respectively. Insulin resistance degree was significantly higher in HP+ group (HP− =3.160±3.327versus HP+ =4.484±3.781,P=0.013) but no significant difference was found between the mean serum adiponectin level in HP− and HP+ groups (P=0.140).Conclusions.Although the insulin resistance degree was significantly higher in HP+ diabetic patients, no significant relationship was found between HP infection and serum levels of adiponectin.

ADIPONECTIN SERUM LEVEL DIFFERENCE IN WOMEN WITH ENDOMETRIOTIC AND NON-ENDOMETRIOTIC CYSTS

2015 ◽  
Vol 1 (2) ◽  
Author(s):  
Ruswana Anwar ◽  
Fahdiansyah Fahdiansyah
Keyword(s):  
Serum Level ◽  
Comparative Study ◽  
Inflammatory Process ◽  
Adiponectin Level ◽  
Stage Iv ◽  
Serum Levels ◽  
Serum Adiponectin ◽  
Cross Sectional ◽  
Endometriotic Cyst ◽  
Low Levels

Endometriosis is an estrogen-dependent disease. Low levels of adiponectin resulted in an increased free estrogen levels and the inability to inhibit angiogenesis and the inflammatory process resulting in the development of increasingly severe endometriosis.This study is aimed to determine the differences in serum adiponectin levels in patient with nonendometriotic cyst with endometriosis cyst and its relationship with endometriosis stages. This is an analytical comparative study with cross-sectional method in group of women with endometriotic cyst (n=25) and women with non-endometriotic cysts (n=25), performed either laparoscopic or laparotomy surgery. The serum levels of adiponectin in both groups then compared with statistical analysis.The results showed there were no significant differences (p>0,05) on the characteristics of the study subjects in terms of age (p=0.994) and BMI (p=0.27). Significant differences of adiponectin levels were found between endometriotic patient group (mean=3.91) and nonendometriotic patients group (mean=8.59). There were no significant differences of adiponectin level in stages III endometriosis (mean = 4.24) and stage IV endometriosis (mean = 3.54).It is concluded that serum adiponectin levels in patients with endometriosis is lower than patient with non-endometriotic cyst. There is no relationship between adiponectin levels with endometriosis stage. Keywords: adiponectin, endometriotic cyst, non-endometriotic cyst, endometriosis stage

scholarly journals Perbedaan kadar hemoglobin pada remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Marianne C. Jacobus ◽  
Max F.J Mantik ◽  
Adrian . Umboh
Keyword(s):  
Analytical Study ◽  
Nutrition Status ◽  
P Value ◽  
Cross Sectional ◽  
Significant Difference ◽  
Good Nutrition ◽  
The Difference ◽  
Cross Sectional Design ◽  
And Gender ◽  
Main Component

Abstract: Haemoglobin is the main component of red blood cells that serves as a transporter of oxygen and carbon dioxide in the blood. The normal range of haemoglobin values can be used to determine the degree of anemia according to age and gender. Geographical condition such as altitude influences the haemoglobin value. This study aimed to obtain the difference of haemoglobin levels between teenagers with good nutrition status who live at the highland and those at the seaside. This was an observational analytical study with a cross sectional design. Samples were students with good nutrition status of SMPN 3 Tomohon (living at the highland) and those of SMP Kristen Nazaret Tuminting (living at the seaside). There were 60 students who met the inclusion criteria as follows: adolescent, good nutrition status, healthy, aged 13-15 years, lived at the highland or at the seaside ≥ 6 month, and willing to be performed blood examinations, and had been approved by their parents. The Mann-Whitney test for the difference between haemoglobin levels of the two groups showed a p value < 0,001. Conclusion: There was a very significant difference between haemoglobin levels of good nutrition teenagers who lived at the highland and at the seaside. Keywords: haemoglobin levels, good nutrition, teenagers, highland, seaside  Abstrak: Hemoglobin merupakan komponen utama sel darah merah dan berfungsi sebagai transporter oksigen dan karbon dioksida dalam darah. Batas normal nilai hemoglobin dapat digunakan untuk menetapkan derajat anemia, dengan distribusi usia dan jenis kelamin spesifik didasarkan pada sampel referensi sehat. Kondisi geografis, seperti ketinggian tempat dari permukaan laut menjadi faktor pertimbangan dalam distribusi nilai normal hemoglobin. Penelitian ini bertujuan untuk mendapatkan perbedaan kadar hemoglobin antara remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai. Jenis penelitian ini analitik-observasional dengan desain potong lintang. Sampel penelitian yaitu remaja gizi baik yang tinggal di pegunungan yaitu siswa SMPN 3 Tomohon dan yang di tepi pantai yaitu siswa SMP Kristen Nazaret Tuminting. Subjek penelitian berjumlah 60 remaja yang memenuhi kriteria inklusi yaitu gizi baik, sehat, berumur 13-15 tahun, berdomisili di pegunungan atau tepi pantai ≥6 bulan, bersedia dilakukan pemeriksaan darah, dan telah disetujui oleh orang tua. Data yang diperoleh dianalisis menggunakan uji Mann-Whitney dengan bantuan program SPSS. Hasil uji Mann-Whitney mengenai perbedaan kadar hemoglobin antara kedua kelompok menunjukkan nila p <0,001. Simpulan: Terdapat perbedaan yang sangat bermakna kadar hemoglobin remaja gizi baik yang tinggal di pegunungan dengan di tepi pantai.Kata kunci: kadar hemoglobin, remaja gizi baik, pegunungan, tepi pantai

scholarly journals PARAS INTERLEUKIN-18 PENDERITA TUBERKULOSIS PARU DAN PERAWAT SEHAT BERISIKOTUBERKULOSIS

2018 ◽  
Vol 14 (2) ◽  
pp. 56
Author(s):  
Sianny Herawati ◽  
J Nugraha
Keyword(s):  
At Risk ◽  
Analytical Study ◽  
Sandwich Elisa ◽  
Active Tuberculosis ◽  
Interleukin 18 ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Care Workers ◽  
Significant Difference ◽  
The Difference

Tuberculosis is an infectious disease which is the second cause of death in the world. Indonesia belongs to the third ranks as themost prevalent tuberculosis country. However the eradication is programmed only to focus on finding the case and treatment of theactive tuberculosis patients. Health care workers are at risk to tuberculosis infection, but there is no examination yet for early detectionactivity of tuberculosis. In order to know the activity of tuberculosis, other examinations are needed such as IL-18 examination. Today, no research about IL-18 is performed yet in Indonesia; therefore this study is performed in order to know the difference of IL-18level in active tuberculosis patients and nurses at risk. This study is to know the difference between IL-18 plasma of active tuberculosispatients and nurses at risk by analysis. A cross sectional, observational analytical study of 8 nurses at risk of tuberculosis and 8 activetuberculosis patients, has been conducted from February up to April 2007, at the Dr. Soetomo General Hospital and Karang TembokHospital in Surabaya. The diagnosis of active tuberculosis patients was based on positive sputum bacteriological examination, positiveradiology examination and who never had received anti-tuberculosis drugs. Nurses at risk of tuberculosis consisted of those who had beenworking more than 2 years, and was examined by negative bacteriological and radiology examination, TB-dot and positive tuberculinskin test with a diameter – 10 mm. IL-18 examination was done by double antibody sandwich ELISA method (MBL/Medical & BiologicalLaboratories Co.Ltd). IL-18 level in active tuberculosis patients was 491.4–1215.3 pg/ml (mean 794.6 pg/ml, SD 222.6), in nursesat risk of tuberculosis was 88.9–429.0 pg/ml (mean 256.2 pg/ml, SD 137.6). There was a significant difference of IL-18 level amongactive tuberculosis patients and nurses at risk of tuberculosis (p < 0.001); the IL-18 level in active tuberculosis patients was significantlyhigher than in nurses at risk of tuberculosis.

scholarly journals Association of Serum Vaspin and Adiponectin Levels with Renal Function in Patients with or without Type 2 Diabetes Mellitus

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Meiyu Yan ◽  
Bin Su ◽  
Wenhui Peng ◽  
Liang Li ◽  
Hailing Li ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Renal Insufficiency ◽  
Filtration Rate ◽  
Adiponectin Level ◽  
Serum Adiponectin ◽  
Diabetic Patients ◽  
Serum Adiponectin Level ◽  
Significant Difference ◽  
Antidiabetic Effects

Vaspin and adiponectin are two adipocytokines with antidiabetic effects. Some studies reported that levels of adiponectin and vaspin were correlated with decreased glomerular filtration rate (FGR) and increased albuminuria. We therefore evaluated the vaspin and adiponectin levels in renal insufficiency (RI) patients with or without T2DM. Serum vaspin, adiponectin levels were measured in 416 subjects with or without T2DM. Analysis was made between groups divided by these subjects presence or absence of RI. We found that serum adiponectin level was significantly higher in nondiabetic patients with RI than in nondiabetic subjects without RI; however, there were no statistical differences between the diabetic patients with RI and without RI. In all the subjects, the serum adiponectin level was also higher in 50 individuals with RI than that in 366 subjects without RI. The serum vaspin levels showed no significant differences between the diabetic patients or nondiabetics subjects with RI and without RI. Contrary to adiponectin, the serum vaspin level was lower in 169 patients with T2DM than in 247 individuals without T2DM. Our data suggested that both of T2DM and renal insufficiency were correlated with the serum level of adiponectin. However, the serum vaspin levels showed no significant difference between the individuals with renal insufficiency and without renal insufficiency.

scholarly journals Perbedaan tinggi badan sebelum tidur dan setelah bangun pagi pada masyarakat subetnis Minahasa di Desa Senduk

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Magdalena I. Simanullang ◽  
George N. Tanudjaja ◽  
Djon Wongkar ◽  
Taufiq F. Pasiak
Keyword(s):  
Human Body ◽  
Analytical Study ◽  
Sampling Method ◽  
Wilcoxon Test ◽  
Cross Sectional ◽  
Purposive Sampling ◽  
Significant Difference ◽  
The Difference ◽  
Cross Sectional Design ◽  
Waking Up

Abstract: Anthropometry is a measurement of certain parts of human body including height. This study was aimed to obtain the difference in height between after waking up in the morning and before going to bed at night among Minahasan sub-ethnic people at Senduk village. This was an analytical study with a cross-sectional design. Sampels were obtained by using purposive sampling method. There were 65 people as subjects. The results showed that the heights after waking up in the morning were longer than the heights before going to bed at night with an average of 1-2 cm for both sexes. The Wilcoxon test showed a significant difference between the heights after waking up in the morning and the heights before going to bed at night (p=0.002 for males and p=0.000 for females). Conclusion: There was a significant difference between the heights after waking up in the morning and the heights before going to bed at night. The heights after waking up in the morning were longer than the heights before going to bed at night.Keywords: height, after waking up in the morning, before going to bed at night Abstrak: Antropometri merupakan sebuah alat ukur yang digunakan untuk mengukur bagian-bagian tubuh manusia termasuk tinggi badan. Penelitian ini bertujuan untuk mendapatkan perbedaan tinggi badan sebelum tidur dan setelah bangun pagi pada sub-etnis Minahasa di Desa Senduk. Jenis penelitian ialah analitik dengan desain potong lintang. Sampel diambil secara purposive sampling sebanyak 65 orang. Hasil penelitian mendapatkan bahwa tinggi badan setelah bangun pagi lebih panjang dibandingkan sebelum tidur malam hari dengan rerata perbedaan 1-2 cm untuk kedua jenis kelamin. Hasil uji Wilcoxon mendapatkan perbedaan bermakna antara tinggi badan setelah bangun pagi dan sebelum tidur (p=0,002 untuk laki-laki dan p=0,000 untuk perempuan). Simpulan: Terdapat perbedaan bermakna antara tinggi badan setelah bangun pagi dan sebelum tidur malam hari. Tinggi badan setelah bangun pagi lebih pendek dibandingkan sebelum tidur malam hari. Kata kunci: tinggi badan, sebelum tidur malam hari, setelah bangun pagi

scholarly journals PERBEDAAN RERATA KADAR NATRIUM MATERNAL ANTARA PREEKLAMPSIA BERAT DAN EKLAMPSIA DI RSUP DR. M. DJAMIL PADANG

2019 ◽  
Vol 2 (1) ◽  
pp. 16-20
Author(s):  
Gunawan Efri ◽  
Dovy Djanas
Keyword(s):  
Analytical Study ◽  
Cross Sectional Study ◽  
Sodium Content ◽  
Severe Preeclampsia ◽  
Cross Sectional ◽  
Blood Electrolytes ◽  
Significant Difference ◽  
The Mean ◽  
The Difference ◽  
Sodium And Potassium

Objective: To determine the difference in mean ratio of sodium content between pregnancy with severe preeclampsia and eclampsia.Method: This is an analytical study using a cross sectional study design. The study was conducted inMaternity room of Dr. M. Djamil Padang from January 15th, 2016 to December 31st, 2017, there were 60 patients as subjects, the sample was divided into 2 groups: severe preeclampsia and eclampsia. Furthermore, history and physical examination to obtain data and clinical diagnosis. Data is recorded in a research form that has been provided, then performed blood electrolytes of Sodium and Potassium. Statistical analysis to assess significance using T-test.Results: In the severe preeclampsia and eclampsia, multiparous parity had the highest respondent. This is consistent with the literature in which the incidence of preeclampsia is more common in late pregnancy.Conclusions: There was no significant difference in the mean sodium ratio between normal severe preeclampsia pregnancy and normal pregnancy.Keywords: pregnancy condition, severe preeclampsia, eclampsia, and sodium.

scholarly journals Expression of the adiponectin gene (ADIPOQ) in the subcutaneous and visceral fatty tissues and the serum adiponectin level in children

2010 ◽  
Vol 56 (6) ◽  
pp. 3-8 ◽  
Author(s):  
A V Kosygina ◽  
V V Sosunov ◽  
V A Peterkova ◽  
I I Dedov
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
Adiponectin Level ◽  
Primary Objective ◽  
Normal Weight ◽  
Serum Adiponectin ◽  
Adiponectin Gene ◽  
Metabolic Disturbances ◽  
Serum Adiponectin Level ◽  
Significant Difference

The primary objective of the present work was to study specific features of adiponectin gene (ADIPOQ) expression in the subcutaneous and visceral fatty tissues along with the serum adiponectin level in children. The secondary objective was to elucidate the relationship between these variables and the basic anthropometric characteristics. The study included a total of 62 patients (31 boys and 31 girls at the age from 2.5 to 18 (median 13.6 (8.5-15.1) years] after they underwent planned surgical interventions. The expression of the adiponectin gene ADIPOQ was determined in paired samples of adipose tissue using the polymerase chain reaction in the real time; in addition, the serum adiponectin levels were measured. The expression of the adiponectin gene ADIPOQ was shown to be unrelated either to the age or to the sex of the children. Nor was there any significant difference between its expression in the subcutaneous and visceral tissues. The highest expression of mRNA encoding for adiponectin was recorded in the children at the Tanner stages 2-3 of sexual development. The ADIPOQ gene expression in the subcutaneous and visceral tissues of overweight children was 22% and 22.6% higher respectively than in the same tissues of normal weight children. Gene expression in the subcutaneous adipose tissue negatively correlated with the serum adiponectin level ( R = –0.38, p = 0.002), BMI SD (R = –0.35, p = 0.004 ), and the waist circumference (R = –0.36, p = 0.004). The results of the study suggest the necessity of further studies to clarify the pathophysiological role of adiponectin in the development of obesity and the related metabolic disturbances.

scholarly journals PERBEDAAN TINGKAT KEPARAHAN PSORIASIS PADA PASIEN PSORIASIS DENGAN DAN TANPA FOKAL INFEKSI

2018 ◽  
Vol 11 (2) ◽  
pp. 80
Author(s):  
Caroline Astrid ◽  
Ismiralda Oke Putranti ◽  
Kurniasih Dwi Purwanti
Keyword(s):  
Public Hospital ◽  
Analytical Study ◽  
Severity Index ◽  
Exclusion Criteria ◽  
Psoriasis Area Severity Index ◽  
Cross Sectional ◽  
Focal Infection ◽  
Significant Difference ◽  
Epidermal Growth ◽  
The Difference

Psoriasis adalah penyakit kulit yang sering dijumpai, kronik, tidak menular, terjadi akibat kelainan kompleks pada pertumbuhan dan diferensiasi epidermal serta abnormalitas multipel dari biokimia, imunologi, dan vaskular. Salah satu faktor risiko psoriasis adalah fokal infeksi. Penelitian ini bertujuan mengetahui perbedaan tingkat keparahan psoriasis pada pasien psoriasis dengan dan tanpa disertai fokal infeksi di RSUD Prof. Dr. Margono Soekarjo, Purwokerto. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross-sectional. Subjek penelitian adalah 40 pasien psoriasis yang berobat di Poli Kulit dan Kelamin RSUD Prof. Dr. Margono Soekarjo pada bulan November hingga Desember 2017 yang memenuhi kriteria inklusi dan eksklusi. Tingkat keparahan psoriasis diukur menggunakan Psoriasis Area Severity Index (PASI). Analisis data menggunakan independent t-test. Rata-rata tingkat keparahan psoriasis pada pasien dengan fokal infeksi 28,63 dan tanpa fokal infeksi 17,29, dengan jenis fokal infeksi didapatkan fokal infeksi intraoral (47,5%) dan genital (2,5%). Perbedaan tingkat keparahan psoriasis pada pasien dengan dan tanpa fokal infeksi didapatkan p = 0,000 (p < 0,05). Terdapat perbedaan signifikan tingkat keparahan psoriasis pada pasien dengan dan tanpa fokal infeksi.     Psoriasis is a common, chronic, noncontagious skin disease, caused by complex abnormal epidermal growth with multiple abnormality of biochemistry, immunology, and vascular. One of psoriasis risk factors is focal infection. This study was an analytical study with cross-sectional approach, to establish the difference of Psoriasis Area Severity Index (PASI) in patients with and without focal infections in Prof. Dr. Margono Soekarjo Public Hospital, Purwokerto. Subjects of this study were psoriasis outpatients in Dermatology and Venereology Clinic in November until December 2017. Forty subjects who fulfilled the inclusion and exclusion criteria were measured using PASI. This study showed the average of the PASI on patients with focal infections was 28.63 and without focal infections was 17.29, with types of the focal infection were intraoral focal infections (47,5%) and genital focal infections (2,5%). The difference of PASI between patients with and without focal infections was significant with p = 0,000 (p < 0,05). There is a significant difference on degree of psoriasis between patients with and without focal infections.

scholarly journals Adiponectin Is Negatively Associated With Disease Activity and Sharp Score in Rheumatoid Arthritis: a Cross-sectional Study on Treatment-naïve Han Chinese Patients

2021 ◽  
Author(s):  
Xixi Chen ◽  
Kaiwen Wang ◽  
Tao Lu ◽  
Jiajia Wang ◽  
Ting Zhou ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Adiponectin Level ◽  
Cross Sectional Study ◽  
Serum Adiponectin ◽  
Sectional Study ◽  
Serum Adiponectin Level ◽  
Cross Sectional ◽  
Sharp Score ◽  
Treatment Naïve

Abstract Background: The association and potential role of the protein hormone adiponectin in autoimmune diseases causing musculoskeletal disorders, including rheumatoid arthritis (RA), are controversial. Conflicting results may arise from the influences of confounding factors linked to genetic backgrounds, disease stage, disease-modifying anti-rheumatic drugs and patients’ metabolic characteristics. Here, we examined serum level of adiponectin and its relationship with disease activity score 28 with erythrocytes sedimentation rate (DAS28[ESR]) and Sharp score in a treatment-naïve Han Chinese RA population.Methods: This cross-sectional study enrolled 125 RA patients. Serum level of total adiponectin was assessed by enzyme-linked immunosorbent assay (ELISA). Other important clinical and laboratory parameters were collected from the hospital database. DAS28(ESR) was calculated according to the equation previously published. Sharp score was evaluated based on hands radiographs by an independent radiologist. The correlation between serum adiponectin level and DAS28(ESR) or the Sharp score was investigated by univariable and multivariable regression analyses. Multiple imputation by chained equations was used to account for missing data.Results: Univariable analyses showed significant positive correlation between DAS28(ESR) and age or C-Reactive Protein (CRP) (both p = 0.003), while serum adiponectin level was negatively correlated with DAS28(ESR) (p = 0.015). The negative correlation between adiponectin level and DAS28(ESR) remained true in multivariable analyses adjusted for confounders. In addition, the univariable analyses revealed positively correlations of Sharp score to disease duration (p < 0.001), CRP (p = 0.023) and ESR (p < 0.001). In the multivariable model adjusted for confounders, adiponectin was negatively correlated with Sharp score (p = 0.044).Conclusion: In this single-institution cross-sectional study, serum adiponectin level in treatment-naive RA patients is negatively correlated with DAS28(ESR) and the Sharp score after adjustment for prominent identified confounders. Serum adiponectin may be potentially useful for assessing disease activity and radiographic progression of RA.

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