scholarly journals Angka Kejadian Pasien Tumor Tulang yang Telah Melakukan Pemeriksaan Foto X-Rays di Instalasi Radiologi RSUD Dr. H. Abdul Moeloek Periode Tahun 2013 – 2018

2021 ◽  
Vol 3 (4) ◽  
pp. 570-577
Author(s):  
M. Rikza Hanif
Keyword(s):  
Bone Tumor ◽  
Bone Tumors ◽  
Bone Growth ◽  
Growth Period ◽  
X Rays ◽  
Tumor Patients ◽  
Cross Sectional ◽  
Primary Bone Tumors ◽  
Adult Age ◽  
Analytic Design

ABSTRACT: NUMBER OF EVENTS OF BONE TUMOR PATIENTS THAT HAVE BEEN CONDUCTING X-RAYS PHOTO EXAMINATION IN RADIOLOGICAL INSTALLATIONS IN RSUD Dr. H. ABDUL MOELOEK PERIOD 2013 - 2018 Background: Bone tumor is a relatively rare disease, in which cells will continue to grow in bone tissue. According to WHO, the incidence of bone tumors is around 4-5 people per 1,000,000 population. The estimated incidence of tumors increases to 8-11 per 1,000,000 population per year at 15-19 years of age. Primary bone tumors are more common in men than in women with a ratio of 3: 2. This could be because the bone growth period in men is longer than in womenThe research objective: to know the incidence rate in bone tumor patients who have undergone X-Rays examination at the Radiology Installation of the Regional General Hospital Dr. H. Abdul Moeloek Period 2013 - 2018.Methods: This type of research is quantitative, descriptive analytic design with cross sectional approach. The population in this study were patients who were clinically diagnosed with Bone Tumors who came to Dr. H. Abdul Moeloek Bandar Lampung January 2013 - December 2018. The sample size of the population taken is at least 30 samples according to the inclusion criteria. Retrieval of data using the observation sheet.Results: Distribution of the frequency of respondents in Dr. Hi. Abdul Moeloek, Lampung Province in 2013-2018 based on the location of the tumor, mostly on the long bones, as many as 26 patients (81.3%). adult age (> 18 years), namely 23 patients (71.9%), female, namely 18 patients (56.3%), treated in 2018 as many as 9 patients (28.1%), long history of diagnosis> 3 months, namely 17 patients (53.1%), the location of the metaphysical bone was 19 patients (59.4%), the tumors were malignant as many as 30 patients (93.8%), there was no congenital history, namely 32 patients (100.0%). Keywords: X-Rays, Bone Tumor  INTISARI: ANGKA KEJADIAN PASIEN TUMOR TULANG YANG TELAH MELAKUKAN PEMERIKSAAN FOTO X-RAYS DI INSTALASI RADIOLOGI  DI RSUD Dr. H. ABDUL MOELOEK PERIODE  TAHUN 2013 –  2018 Latar Belakang : Tumor tulang merupakan penyakit yang relatif langka, dimana sel-sel  akan terus tumbuh pada jaringan tulang. Menurut WHO insiden terjadinya tumor tulang sekitar 4-5 orang per 1.000.000 penduduk. Perkiraan insiden tumor meningkat menjadi 8-11 per 1.000.000 penduduk per tahun pada usia 15-19 tahun. Tumor tulang primer lebih sering terjadi pada pria dari pada wanita dengan perbandingan 3:2. Hal ini bisa disebabkan karena masa pertumbuhan tulang pada pria lebih lama dari pada wanitaTujuan penelitian:  Diketahui  Angka Kejadian pada pasien Tumor Tulang yang Telah Melakukan Pemeriksaan Foto X-Rays di Instalasi Radiologi Rumah Sakit Umum Daerah Dr. H. Abdul Moeloek Periode Tahun 2013 - 2018.Metode Penelitian : Jenis penelitian kuantitatif, rancangan deskriptif analitik dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah pasien yang terdiagnosis secara klinis Tumor Tulang yang datang ke RSUD Dr. H. Abdul Moeloek Bandar Lampung Januari 2013 - Desember 2018. Besar sample terhadap populasi yang diambil minimal 30 sample sesuai dengan kriteria inklusi. Pengambilan data menggunakan lembar observasi.Hasil penelitian : Distribusi frekuensi responden di RSUD Dr. Hi. Abdul Moeloek Provinsi Lampung Tahun 2013-2018 berdasarkan lokasi tumor, sebagian besar pada tulang panjang yaitu sebanyak 26 pasien (81,3%). berusia dewasa (> 18 tahun) yaitu 23 pasien (71.9%), berjenis kelamin perempuan yaitu sebanyak 18 pasien (56.3%), dirawat pada tahun 2018 yaitu sebanyak 9 pasien (28.1%), riwayat lama diagnosa > 3 bulan yaitu sebanyak 17 pasien (53,1%), lokasi tulang metafisis yaitu sebanyak 19 pasien (59,4%), tumor bersifat malignan yaitu sebanyak 30 pasien (93,8%), tidak ada riwayat kongenital yaitu sebanyak 32 pasien (100,0%). Kata Kunci    : Foto X-rays, Tumor Tulang

Onlay Silicone and Hydroxyapatite-Tricalciumphosphate Composite (HAP-TCP) Blocks Interfere with Nasal Bone Growth in Rabbits

1995 ◽  
Vol 32 (4) ◽  
pp. 282-289
Author(s):  
Minoru Arakaki ◽  
Shunichi Yamashita ◽  
Mehmet Mutaf ◽  
Shinji Naito ◽  
Tohru Fujii
Keyword(s):  
Bone Tissue ◽  
Bone Growth ◽  
Nasal Bone ◽  
Growth Period ◽  
Blood Biochemistry ◽  
Hydroxyapatite Ceramic ◽  
Cross Sectional ◽  
Porous Hydroxyapatite ◽  
New Type ◽  
The Right

We investigated how a new type of synthetic porous hydroxyapatite ceramic (HAP-TCP) acts when it is implanted in growing membranous bone. Seventy-six New Zealand White infant male rabbits (4-week-olds) were used. Rabbits received HAP-TCP block or silicone block implantation in their right nasal bone. The left nasal bone was used for a sham. Serial or cross-sectional examinations by morphometry, radiology, blood biochemistry, and histology were carried out. Both the HAP-TCP and silicone groups exhibited no systemic growth disturbance in terms of morphometry and blood biochemistry. Dual energy x-ray absorptiometry (DEXA) revealed, however, a decrease in the bone mineral content (BMC) of the right nasal bone in the silicone group. Histology revealed a superior affinity of HAP-TCP to bone tissue than that of silicone. When a HAP-TCP block was implanted under the periosteum it bonded directly to bone tissue. However, sinking of the implants into the bone tissue were noted both in the HAP-TCP and the silicone groups in longitudinal observation. These results suggest that although HAP-TCP has superior affinity to bone tissue, this by itself is not enough sufficient reason to believe that HAP-TCP can be effectively applied during the growth period.

scholarly journals Demographic, clinico-pathological features and management pattern of primary bone tumors in a tertiary care hospital of South India

2021 ◽  
Vol 8 (1) ◽  
pp. 60
Author(s):  
Subbiah Shanmugam ◽  
Sujay Susikar ◽  
Bharanidharan T. ◽  
Arun Victor Jebasingh
Keyword(s):  
Bone Tumor ◽  
Bone Tumors ◽  
Tertiary Care ◽  
Tumor Location ◽  
Care Hospital ◽  
Pathological Features ◽  
Primary Bone Tumor ◽  
Primary Bone Tumors ◽  
True Incidence ◽  
Primary Bone

<p><strong>Background</strong>: Primary bone tumors are very rare tumors. The true incidence of bone tumors is not well established and is under reported due to rarity and lack of accurate registries. Hence it is essential to study about the demographic, clinico-pathological features and the pattern of surgical management of bone tumors. The aim of this study is to analyze the demographic and clinico-pathological features of primary bone tumors that were managed by surgery.</p><p><strong>Methods</strong>: A retrospective analysis of all patients with primary bone tumor who were treated by surgery from 2012 to 2019 was done. The age, sex distribution, histopathology, location of the tumor and surgical procedure done were analyzed.</p><p><strong>Results</strong>: Among 103 patients analyzed, 66 (64%) were men and 37 (36%) were women. Primary bone tumors most commonly presented in 11 to 20 years of age with 35 (33.9%) patients occurring in this age group. Osteosarcoma was the most common primary bone tumor and it occurred in 49 (47.6%) patients, out of which 34 (69.3%) patients were below 20 years of age. Giant cell tumor was the most common benign bone tumor and it occurred in 22 patients, out of which nine (40.9%) patients were of age 21 to 30 years. Distal femur was the most common site with 39 (37.9%) patients. The limb preservation rate for malignant appendicular bone tumors was 69.0%.</p><p><strong>Conclusions</strong>: The diagnosis of bone tumor depends not only on histopathological features but also needs correlation with age, clinical features, tumor location and radiological features for confirmation of diagnosis.</p>

scholarly journals Profile of Musculoskeletal Tumor in Saiful Anwar General Hospital Malang from January 2011 until December 2018

2020 ◽  
Vol 16 (2) ◽  
pp. 81
Author(s):  
Istan Irmansyah Irsan ◽  
Satria Pandu Persada Isma ◽  
Abdul Aziz ◽  
Muhammad Hilman Bimadi ◽  
I Gusti Ngurah Arga Aldrian Oktafandi
Keyword(s):  
Soft Tissue ◽  
General Hospital ◽  
Bone Tumor ◽  
Bone Tumors ◽  
Malignant Tumors ◽  
Soft Tissue Tumors ◽  
Musculoskeletal Tumor ◽  
Primary Bone Tumors ◽  
Musculoskeletal Tumors ◽  
Primary Bone

Abstract: Musculoskeletal tumors are relatively rare, with 0.2%-0.5% of all malignant tumors in all ages. The geographic distribution of musculoskeletal tumors varies significantly around the world. This study aims to describe the musculoskeletal tumor profile in Saiful Anwar General Hospital. All data were obtained from the department of orthopaedic and traumatology database, Saiful Anwar general hospital. Thus, patients who were diagnosed with either bone tumor or soft tissue tumor between January 2011 to December 2018 were selected for the present study. The clinical-pathological conference (CPC) was carried out to ensure the validity of all the registered data. A total of 577 patients with tumors from January 2011 to December 2018 was obtained. Out of all the cases, 439 (76%) cases are bone tumors, and the remaining 138 (24%) cases are soft tissue tumors. The most frequent locations of the musculoskeletal tumors are the long bones of the thigh and lower leg. This study shows an increasing trend in musculoskeletal tumors incidence, despite decreasing numbers in several years. This result goes along with a rising trend in malignancy cases with a higher amount compared to the benign one. Moreover, MBD and osteosarcoma were found to be the most common tumor and primary bone tumors, respectively. However, the fact that there is some data loss in the study limited the study for a more accurate result.   Keywords: Musculoskeletal tumor; Bone tumor; Osteosarcoma; Malang; East Java

X-ray micro tomography in the scanning electron microscope

1978 ◽  
Vol 36 (1) ◽  
pp. 106-107 ◽  
Author(s):  
W. Brünger
Keyword(s):  
Electron Beam ◽  
Electron Microscope ◽  
Scanning Electron Microscope ◽  
Target Surface ◽  
The Body ◽  
X Rays ◽  
Cross Sectional ◽  
X Ray ◽  
Micro Tomography ◽  
Scanning Electron

Reconstructive tomography is a new technique in diagnostic radiology for imaging cross-sectional planes of the human body /1/. A collimated beam of X-rays is scanned through a thin slice of the body and the transmitted intensity is recorded by a detector giving a linear shadow graph or projection (see fig. 1). Many of these projections at different angles are used to reconstruct the body-layer, usually with the aid of a computer. The picture element size of present tomographic scanners is approximately 1.1 mm2.Micro tomography can be realized using the very fine X-ray source generated by the focused electron beam of a scanning electron microscope (see fig. 2). The translation of the X-ray source is done by a line scan of the electron beam on a polished target surface /2/. Projections at different angles are produced by rotating the object.During the registration of a single scan the electron beam is deflected in one direction only, while both deflections are operating in the display tube.

Characterization of Rh/Si multilayer structure by HREM and HAADF

1992 ◽  
Vol 50 (1) ◽  
pp. 122-123
Author(s):  
Y. Cheng ◽  
J. Liu ◽  
M.B. Stearns ◽  
D.G. Steams
Keyword(s):  
Normal Incidence ◽  
High Resolution Electron Microscopy ◽  
X Rays ◽  
Beam Direction ◽  
Cross Sectional ◽  
Optical Elements ◽  
Resolution Electron ◽  
Point To Point ◽  
Better Than

The Rh/Si multilayer (ML) thin films are promising optical elements for soft x-rays since they have a calculated normal incidence reflectivity of ∼60% at a x-ray wavelength of ∼13 nm. However, a reflectivity of only 28% has been attained to date for ML fabricated by dc magnetron sputtering. In order to determine the cause of this degraded reflectivity the microstructure of this ML was examined on cross-sectional specimens with two high-resolution electron microscopy (HREM and HAADF) techniques.Cross-sectional specimens were made from an as-prepared ML sample and from the same ML annealed at 298 °C for 1 and 100 hours. The specimens were imaged using a JEM-4000EX TEM operating at 400 kV with a point-to-point resolution of better than 0.17 nm. The specimens were viewed along Si [110] projection of the substrate, with the (001) Si surface plane parallel to the beam direction.

Scintigraphy with 99m Tc-Phosphonate and 67Gallium in Patients Suspected of Primary Bone Tumors

1982 ◽  
Vol 21 (04) ◽  
pp. 136-139 ◽  
Author(s):  
C.-J. Edeling
Keyword(s):  
Soft Tissue ◽  
Bone Scintigraphy ◽  
Primary Tumor ◽  
Bone Tumors ◽  
Whole Body ◽  
Skeletal Metastases ◽  
Malignant Bone Tumors ◽  
67Ga Scintigraphy ◽  
Primary Bone Tumors ◽  
Primary Bone

Whole-body scintigraphy with both 99mTc-phosphonate and 67Ga was performed on 92 patients suspected of primary bone tumors. In 46 patients with primary malignant bone tumors, scintigraphy with 99mTc-phosphonate disclosed the primary tumor in 44 cases and skeletal metastases in 11, and 67Ga scintigraphy detected the primary tumor in 43 cases, skeletal metastases in 6 cases and soft-tissue metastases in 8 cases. In 25 patients with secondary malignant bone tumors, bone scintigraphy visualized a single lesion in 10 cases and several lesions in 15 cases, and 67Ga scintigraphy detected the primary tumor in 17 cases, skeletal metastases in 17 cases and soft-tissue metastases in 9 cases. In 21 patients with benign bone disease positive uptake of 99mTc-phosphonate was recognized in 19 cases and uptake of 67Ga in 17 cases. It is concluded that bone scintigraphy should be used in patients suspected of primary bone tumors. If malignancy is suspected, 67Ga scintigraphy should be performed in addition.

CRYOSURGERY IN THE TREATMENT OF PATIENTS WITH BONE TUMORS

2019 ◽  
Vol 65 (2) ◽  
pp. 165-171
Author(s):  
Aleksey Belyaev ◽  
Georgiy Prokhorov ◽  
Anna Arkhitskaya
Keyword(s):  
Liquid Nitrogen ◽  
Bone Tumors ◽  
Cryogenic Treatment ◽  
Long Term Results ◽  
Bone Lesions ◽  
Giant Cell Tumors ◽  
Primary Bone Tumors ◽  
Circulation Circuit ◽  
Recent Emergence ◽  
Primary Bone

A review of the literature shows that surgical procedures will remain the standard treatment for primary bone tumors. Analysis of studies on the assessment of long-term results shows that additional double cryogenic treatment of the curettage cavity can improve the treatment outcomes of patients with giant cell tumors, dysplastic diseases and some forms of malignant lesions. The traditional execution of the procedure is associated with the open installation of liquid nitrogen in the bone cavity, which requires special skills in handling aggressive refrigerant from the staff and does not exclude complications. In case of multiple metastatic bone lesions, surgical treatment is not indicated. The recent emergence in clinical practice of new equipment with a closed liquid nitrogen circulation circuit inside cryoprobes resumes interest in cryoabla-tion of bone tumor lesions using modern minimally invasive puncture cryotechnology and expanding indications for its use in patients with severe comorbidities.

scholarly journals FRI0499 ACROMEGALY ARTROPATHY: IS THERE SOMETHING MORE BEHIND THE PAIN? A CROSS-SECTIONAL STUDY TO EVALUATE RHEUMATIC DISEASE IN GROWTH HORMONE SECRETING TUMOR PATIENTS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 848.1-848
Author(s):  
M. Scarati ◽  
S. Parisi ◽  
N. Prencipe ◽  
M. C. Ditto ◽  
E. Ghigo ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Logistic Regression ◽  
Rheumatic Disease ◽  
Power Doppler ◽  
Connective Tissue Diseases ◽  
Joint Damage ◽  
Joint Space ◽  
Tumor Patients ◽  
Cross Sectional ◽  
Significant Difference

Background:Acromegaly is a rare disease with a remarkable impact on patients, both in terms of life expectancy and quality of life. Osteo-articular complications are one of the most frequently reported bothers. The “acromegaly artropathy” characterizes more than 70% of patients at diagnosis. Artropathy affects both spine and peripheral joints. A recent prospective study documented progression of acromegalic arthropathy identified as a worsening of osteophytes and joint space narrowing in 72–74% of patients despite long-term biochemical control. In addiction the Literature has occasionally reported cases of simultaneous presence of rheumatic diseases (rheumatoid arthritis, polymyalgia rheumatica, undifferentiated connective tissue diseases) and acromegaly and in all these cases the treatment has been delayed, because of wrong symptoms attribution to acromegaly artropathy.Objectives:The primary goal of the study is to better characterize joint pain in acromegaly patients and to evaluate the prevalence of rheumatic disease in growth hormone (GH) secreting pituitary tumor patients.Methods:We enrolled 20 acromegaly subjects (AS) and 20 control subjects (CS). In each subject immunological pattern (rheumatoid factor – RF; antinuclear antibodies - ANA, ENA; anti-citrullinated protein antibodies - ACPA; erythrocyte sedimentation rate – ESR) has been evaluated; they, also, underwent bilateral joint ultrasound of hands and wrists and nail capillaroscopy. The Chi square test and the Fisher’s exact test were used to evaluate the association between binary variables, while the Spearman’s test to evaluate the correlation of continuous ones. A multiple or logistic regression model was calculated in order to define the association between the capillaroscopic alterations and other detected variables.Results:Articular pain emerged as significantly more frequent in AS (p = 0.0269). No statistically significant differences are detected regarding immunological pattern. ANA and ENA screening resulted positive in 10% in AS and in 5% in CS. No IgA ACPA were detected in AS or CS, while IgG ACPA were positive only in one AS subject. No significant differences were detected between IgM and IgG RFin the two groups (AS 5% and CS 0%). Three fold higher IgG FR in AS compared to CS were detected. ESR levels were significantly higher than CS (p = 0.0405), as well as increased power doppler (PWD) articular uptake (AS 30% vs CS 5% p 0.081). The capillaroscopic evaluation showed a significant difference in almost each parameter that has been evaluated (logistic regression: number of enlargement p 0.004, hemorragies p 0.01 and capillaries p 0.001), showing a moderate-severe microangiopathy in AS. Interestingly, analyzing only the acromegaly cohort, we noticed higher GH levels at the enrollment in patients which developed capillary enlargements (GH: 0.95 ng/ml IQ 0,6-1,6) compared to other ones (GH: 0.55 ng/ml IQ 0.4-0.7; p = 0.08) and a significant lower number of hemorrhages (p = 0.02) in patients treated with GH antagonist pegvisomant.Conclusion:Our results demonstrated that joint damage in acromegaly does not seem to have an autoimmune etiology. Therefore, articular damage is mechanical and increased ESR and PWD alterations seems to confirm the presence of an inflammatory component. In addition, acromegaly is characterized by a microvascular pattern of moderate-severe microangiopathy, without correlation to IGF-I, but GH levels. Although requiring further confirmatory studies, our preliminary results seem to indicate how the capillaroscopic examination could be useful to detect earlier microangiopathy and to identify patients with a greater risk of macroangiopathy development..References:[1]Claessen KMJA et al. Bone and joint disorders in acromegaly. Neuroendocrinology. 2016;103(1):86-95.[2]Örük G et al. Is every joint symptom related to acromegaly? Endocrine. 2013 Apr;43(2):404-11.Disclosure of Interests:None declared

Effect of an interval rehabilitation program with home-based, vibration-assisted training on the development of muscle and bone in children with cerebral palsy – an observational study

2020 ◽  
Vol 33 (8) ◽  
pp. 1083-1092 ◽  
Author(s):  
Ibrahim Duran ◽  
Kyriakos Martakis ◽  
Christina Stark ◽  
Leonie Schafmeyer ◽  
Mirko Rehberg ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Bone Growth ◽  
Muscle Growth ◽  
Rehabilitation Program ◽  
Whole Body ◽  
Cross Sectional ◽  
Home Based ◽  
Children With Cerebral Palsy ◽  
One Year ◽  
Intensive Rehabilitation

AbstractObjectivesIn children with cerebral palsy (CP), the most common cause of physical impairment in childhood, less muscle and bone growth has been reported, when compared with typically developing children. The aim of this study was to evaluate the effect of an intensive rehabilitation program including physiotherapy in combination with 6 months of home-based, vibration-assisted training on muscle and bone growth in children with CP.MethodsWe included children with CP, who participated in a rehabilitation program utilizing whole-body vibration (WBV). Muscle mass was quantified by appendicular lean mass index (App-LMI) and bone mass by total-body-less-head bone mineral content (TBLH-BMC) assessed by Dual-energy X-ray absorptiometry (DXA) at the beginning of rehabilitation and one year later. To assess the functional muscle-bone unit, the relation of TBLH-BMC to TBLH lean body mass (TBLH-LBM) was used.ResultsThe study population included 128 children (52 females, mean age 11.9 ± 2.7). App-LMI assessed in kg/m2 increased significantly after rehabilitation. The age-adjusted Z-score for App-LMI showed no significant change. TBLH-BMC assessed in gram increased significantly. The Z-scores for TBLH-BMC decreased lesser than expected by the evaluation of the cross-sectional data at the beginning of rehabilitation. The parameter $\frac{TBLH-BMC}{TBLH-LBM}$ did not change relevantly after 12 months.ConclusionsMuscle growth and to a lesser extent bone growth could be increased in children with CP. The intensive rehabilitation program including WBV seemed to have no direct effect on the bone, but the observed anabolic effect on the bone, may only been mediated through the muscle.

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