scholarly journals Know the unknown fact of novel COVID -19 corona virus

2020 ◽  
Vol 9 (2) ◽  
pp. 1083-1088
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
World Health ◽  
The Novel ◽  
Shortness Of Breath ◽  
Corona Virus ◽  
First Case ◽  
Kerala State ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Learning Points

Coronavirus disease (COVID-19) is a contagious disease triggered by the novel coronavirus. A novel coronavirus was observed as the causative agent and was subsequently termed COVID-19 by the World Health Organization (WHO). In December 2019, a disruption of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections appeared in Wuhan, Hubei Province, China and spread across China and beyond. In India, the first case of CORONA virus was reported in Kerala state on 30 January 2020. The most common symptoms of COVID-19 are fever, cough, shortness of breath, and breathing difficulties. In more severe cases infection can give rise to pneumonia, severe acute respiratory syndrome, and even death. The period within which the symptoms would appear is 1-14 days i.e. the incubation period of COVID-19. The present review highlights the types, etiology, transmission stages, manifestations, prevention, therapeutic options, learning points from outbreak, and initiative taken by Government of India (GOI) to control the spread of literary deathly disease.

scholarly journals Histopathology and Pathogenesis of Coronavirus disease 2019 (COVID-19)

2020 ◽  
Vol 2 (3) ◽  
pp. 230-234
Author(s):  
Nikolaos Chrysanthakopoulos ◽  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Immune Responses ◽  
Good Prognosis ◽  
Multiple Organ ◽  
World Health ◽  
The Novel ◽  
Angiotensin Converting Enzyme 2 ◽  
Corona Virus ◽  
Novel Coronavirus ◽  
Health Organization

A severe pandemic of CoronaVirus disease 2019 (COVID-19), according to World Health Organization (WHO), appeared in China in December 2019, and spread rapidly. The majority of the patients had mild symptoms and good prognosis after recovery; however some patients developed severe inflammatory reaction and passed away from multiple organ complications. The novel coronavirus, Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) is a beta-coronavirus and is similar with the Severe Acute Respiratory Syndrome Corona Virus 1 (SARS-CoV-1) and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV). SARS-CoV-2 and -1 have the same host receptor, the angiotensin-converting enzyme 2 (ACE2). The pathogenesis of SARS-CoV-2 infection in humans remains unclear. The immune response is essential to control and reduce SARS-CoV-1 and -2 infections, however, irregular and exaggerated immune responses may lead to the immunopathology of the disease and the lung lesions. This article presents the immunological features of SARS-CoV-2 infection and its potential pathogenesis based on the recent observations of the International literature.

scholarly journals The First Case of Reactive Arthritis Associated with SARS-CoV-2-Infection in A 4-Year Old Child

2020 ◽  
Author(s):  
Stephanie Gabriele Werner ◽  
Hans-Eckhard Langer
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Reactive Arthritis ◽  
Virus Disease ◽  
The Novel ◽  
Case Presentation ◽  
Corona Virus ◽  
First Case ◽  
Novel Coronavirus ◽  
The Right

Abstract Background: The novel coronavirus SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus 2) and its associated disease COVID‐19 (Corona Virus Disease 19) has become a worldwide pandemic since its first cases in December 2019 in Wuhan Province in China. In Germany the pandemic started in February 2020.Case presentation: A 4 year old boy was presented and suffered from pain in the right hip. Arthrosonography demonstrated a significant effusion in the involved joint. The extended history revealed a slight but long lasting cold before. Serological findings were inconspicuous except for positive ELISA (Enzyme-linked Immuno Sorbent Assay) - test for SARS-CoV-2. Conclusion: In conclusion we believe that we can report the first case of reactive arthritis associated with SARS-CoV-2 in children.

scholarly journals COVID-19: an Indian perspective

2020 ◽  
Vol 7 (5) ◽  
pp. 2003
Author(s):  
Prahlad Kadambi
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
World Health Organization ◽  
Index Case ◽  
World Health ◽  
Corona Virus ◽  
First Case ◽  
The World ◽  
Health Organization ◽  
The University ◽  
Indian Perspective

Severe acute respiratory syndrome coronavirus 2 is currently spreading globally rapidly. The World Health Organization (WHO) named the virus as the 2019 novel corona virus (2019-nCoV) on January 7, 2020. On February 11th 2020, the illness associated was named as 2019 coronavirus disease (COVID-19). Subsequently, the WHO declared COVID-19 as a pandemic on 11 March 2020. The first case of COVID-19 was reported in India on 30 January 2020 in Thrissur, Kerala. This was the index case in India who tested positive after coming for a vacation. This individual was a student of the University of Wuhan. Subsequent cases were reported in Kerala. Subsequently, the number of cases in India increased to 519 as on 24th March 2020 with mortality in 7 patients as on 22nd March 2020 and 10 patients on 24th March 2020.

scholarly journals Immunity Boosting measures during COVID– 19

2020 ◽  
Vol 6 (2) ◽  
pp. 40-42
Author(s):  
Tuba Tanveer ◽  
Keyword(s):  
Preventive Measures ◽  
Daily Practice ◽  
World Health ◽  
The Novel ◽  
Global Level ◽  
Human Race ◽  
Corona Virus ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Disease Epidemics

Viral pneumonia outbreak in Wuhan, China, in 2019 was observed and a novel coronavirus was identified as the cause of this outbreak. COVID-19 was the official term given by the World Health Organization and announced this on February 11, 2020 publicly. Corona virus spreads through person to person contact. The novel corona virus has taken a few months to sweep the globe, there are certain questions that are impossible to fathom as the disease rages. As the vaccine for Covid-19 is not yet discovered, the virus is being controlled from spreading worldwide through numerous strategies. Therefore, noticing the virulence of this virus several preventive measures have been taken at a global level to protect the human race. One of the effective measures in controlling the spread of respiratory disease epidemics is maintaining social distance and, therefore, can be used as a way to reduce its spread. Improving the immune power of a person is another crucial measure adopted to obviate its spread. AYUSH system of medicine is performing a central role in the contribution of meliorating the immune system of a person. Variety of herbal combinations have proven to perform the same function. The very first and easy way to boost the immunity and kill the virus, is to drink warm water throughout the day. It is further also advised to take steam once a day. 30 minutes of daily practice of Yogasana, Pranayama and meditation contributes in boosting immunity. Also using Dhaniya, Haldi, Jeera and Lahsun in cooking helps. It is also advised to use Half teaspoon Haldi with 150 ml of Hot milk, once or twice a day. Consuming Chyavanprash 10 mg in the morning is equally helpful.

The novel coronavirus and its possible treatment by vaccines, therapeutics and drug delivery systems: Current status and future perspectives

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 54-61 ◽  
Author(s):  
Madhurya Kadavakollu ◽  
Veera Venkata Satyanarayana Reddy Karri ◽  
Kuppusamy Gowthamarajan ◽  
Arun Radhakrishnan ◽  
Dhanabal Palanisamy ◽  
...  
Keyword(s):  
Virus Disease ◽  
World Health ◽  
Current Status ◽  
The Novel ◽  
Future Perspectives ◽  
Epidemic Disease ◽  
Wuhan City ◽  
Corona Virus ◽  
Novel Coronavirus ◽  
Health Organization

In the mid-end of December 2019, several cases of pneumonia outbreak of unknown cause and etiology were identified in Wuhan City of Hubei province in China, a city with a population of over 11 million.Till date(April 2020) around 1,051,635 confirmed cases of coronavirus disease 2019(COVID-19) and 56,985 confirmed deaths have been reported according to COVID-19 Situation Report – 75 by WHO. On 7th January 2020, the causative agent was identified and named consequently as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) by the Chinese Centre for Disease Control and Prevention (CCDC) from throat swab samples. Later, on 12th January 2020, this coronavirus was named as 2019-novel coronavirus (2019-nCoV) by World Health Organization (WHO) and in 11th February 2020,it has been declared the epidemic disease caused by SARS-CoV-2 as Corona Virus Disease 2019(COVID-19) as it is spreading rapidly from its origin in Wuhan City to the rest of the world. In this context, the current review provides a landscape of the novel Corona Virus including its origin, transmission, epidemiology, drugs and vaccines in clinical trials for better understanding to the reads and peoples the status and future perspectives of this pandemic disease

scholarly journals Novel Coronavirus Disease (COVID-19): An Update

2020 ◽  
Vol 22 (1-2) ◽  
pp. 93-98
Author(s):  
Niranjan Nayak ◽  
SK Rai
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
World Health Organization ◽  
Social Distance ◽  
Virus Disease ◽  
Hand Washing ◽  
World Health ◽  
Corona Virus ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Wet Market

At present, a novel Corona Virus called Severe Acute Respiratory Syndrome corona virus (SARS-Cov-2) has caused pandemic infection. This virus has been thought to be of zoonotic origin specially originating from bats. This Virus originated from wet market in Wuhan, China in December 2019. A small cluster of Pneumonia cases that occured in Wuhan in December 2019 was named COVID-19 (Corona Virus Disease) by World Health Organization (WHO). The Covid-19 is still on the rise across the globe. As there is no treatment available for the SARS-Cov-2, it is important to mantain social distance, practice frequent hand-washing and use mask.

scholarly journals Perceived Myths and Misconceptions about the Novel COVID-19 Outbreak

2020 ◽  
Vol 2 (3) ◽  
pp. 108-117
Author(s):  
Michael Abiola Okunlola ◽  
Emmanuel Lamptey ◽  
Ephraim Kumi Senkyire ◽  
Serwaa Dorcas ◽  
Benita Aki Dooshima
Keyword(s):  
Face Mask ◽  
The Elderly ◽  
World Health ◽  
Survey Method ◽  
The Novel ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Corona Virus ◽  
Novel Coronavirus ◽  
Health Organization

The outbreak of the novel Coronavirus (Covid-19) which was first reported in Wuhan, China has now spread globally becoming a matter of international concern. The World Health Organization officially changed their classification of the situation from a Public Health Emergency of International Concern to a Pandemic on March 11, 2020. As the corona virus continues to spread rapidly so do the headline news and a host of misconceptions surrounding the outbreak. This paper investigated and highlighted some of the most common misconceptions surrounding the outbreak of the covid-19. Using a cross-sectional survey method, the study collected and analysed data on these misconceptions and examined factors that influence the levels of these misconceptions. The study identified four top misconceptions respondents believe or agree with. These are; the novel corona virus is deadly (83.3%), Hand sanitizers do kill the virus (67.5%), face mask offer protection against the virus (55.8%) and Drying the hands with hand dryer helps to prevent the virus (44.2%). However, respondents were able to disagree, identify correctly and debunked certain statements of misconception. These include coronavirus affect only the elderly (95%), the virus can spread by mosquito bites (87.5%), antibiotics are effective for treatment (60%) and homemade remedies can cure the corona virus (54. 2%). Factors such as employment status and the relatedness of respondent’s occupation to Human Health were found to influence some of these misconceptions. Exploring these misconceptions keep the general public fully educated and informed about the facts of the outbreak as well as avoiding making up these misconceptions to protect themselves.

Novel Coronavirus Disease (COVID-19): A Narrative Review Based on Current Status

2020 ◽  
Vol 18 ◽  
Author(s):  
Rina Das ◽  
Dinesh Kumar Mehta ◽  
Meenakshi Dhanawat
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Clinical Symptoms ◽  
Virus Disease ◽  
Relevant Literature ◽  
World Health ◽  
Current Status ◽  
Future Research ◽  
Treatment And Prevention ◽  
First Case ◽  
Novel Coronavirus

Abstract:: A novel virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), appeared and expanded globally by the end of year in 2019 from Wuhan, China, causing severe acute respiratory syndrome. During its initial stage, the disease was called the novel coronavirus (2019-nCoV). It was named COVID-19 by the World Health Organization (WHO) on 11 February 2020. The WHO declared worldwide the SARS-CoV-2 virus a pandemic on March 2020. On 30 January 2020 the first case of Corona Virus Disease 2019 (COVID-19) was reported in India. Now in current situation the virus is floating in almost every part of the province and rest of the globe. -: On the basis of novel published evidences, we efficiently summarized the reported work with reference to COVID-19 epidemiology, pathogen, clinical symptoms, treatment and prevention. Using several worldwide electronic scientific databases such as Pubmed, Medline, Embase, Science direct, Scopus, etc were utilized for extensive investigation of relevant literature. -: This review is written in the hope of encouraging the people successfully with the key learning points from the underway efforts to perceive and manage SARS-CoV-2, suggesting sailent points for expanding future research.

scholarly journals Potential of CRISPR/Cas13 System in Treatment and Diagnosis of COVID-19

2021 ◽  
Author(s):  
Amir Khodavirdipour ◽  
Motahareh Piri ◽  
Sarvin Jabbari ◽  
Mohammad Khalaj-kondori
Keyword(s):  
Diagnostic Tool ◽  
Human Kidney ◽  
World Health ◽  
Rapid Review ◽  
The Novel ◽  
Rapid Action ◽  
Antiparasitic Drug ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Treatment And Diagnosis

AbstractThe novel coronavirus disease 2019 (COVID-19) belongs to coronaviridae families, like sarbecovirus (SARS), and causes pyrexia, pertussis, and acute respiratory distress syndrome (ARDS) in major. Started from Wuhan, China now forced the World Health Organization (WHO) to call it a pandemic. These dreadful figures elevate the need for rapid action for a rapid diagnostic tool, an efficacious therapy, or vaccine for such widespread disease. Here we reviewed all the latest research and trials including conventional antiviral medicines that have a narrow and finite effect on COVID-19. Recently, some advances have been made by a nucleotide/nucleoside analogues (NUC) inhibitor (remdesivir), ivermectin (antiparasitic drug), and convalescent plasma, the later one has more recently been approved by the Food and Drug Administration (FDA). In addition, a clinical-grade soluble human angiotensin-converting enzyme (ACE2), named hrsACE2, was able to inhibit the infection of human blood vessel organoids, as well as the human kidney organoids, by the virus. As of now, innovative therapeutics based on the CRISPR/Cas13d might overcome the challenge of COVID-19 either as a treatment option or precise and rapid diagnostic tool due to its rapid and precise nature. In this updated comprehensive rapid review, we try to cover all recent findings in terms of genomics, diagnosis, prevention, and treatment.

scholarly journals Progression and Trends in Virus from Influenza A to COVID-19: An Overview of Recent Studies

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1145
Author(s):  
Hakimeh Baghaei Daemi ◽  
Muhammad Fakhar-e-Alam Kulyar ◽  
Xinlin He ◽  
Chengfei Li ◽  
Morteza Karimpour ◽  
...  
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
World Health ◽  
H1n1 Pandemic ◽  
Global Pandemic ◽  
First Case ◽  
Influenza A H1n1 ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization

Influenza is a highly known contagious viral infection that has been responsible for the death of many people in history with pandemics. These pandemics have been occurring every 10 to 30 years in the last century. The most recent global pandemic prior to COVID-19 was the 2009 influenza A (H1N1) pandemic. A decade ago, the H1N1 virus caused 12,500 deaths in just 19 months globally. Now, again, the world has been challenged with another pandemic. Since December 2019, the first case of a novel coronavirus (COVID-19) infection was detected in Wuhan. This infection has risen rapidly throughout the world; even the World Health Organization (WHO) announced COVID-19 as a worldwide emergency to ensure human health and public safety. This review article aims to discuss important issues relating to COVID-19, including clinical, epidemiological, and pathological features of COVID-19 and recent progress in diagnosis and treatment approaches for the COVID-19 infection. We also highlight key similarities and differences between COVID-19 and influenza A to ensure the theoretical and practical details of COVID-19.

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