scholarly journals HbA1C Level in 2nd and 3rd Trimester with Pregnancy Outcome in Diabetic Patients

2012 ◽  
Vol 2 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Ruma Sengupta ◽  
Soha Jesmen ◽  
Laila Arjuman Banu ◽  
Samir Humyra Habib

Objective: The present study was undertaken to determine the association of maternal serum HbA1C level with maternal and fetal outcome. Materials and Methods: It was prospective observational study. The study was carried out in the department of Obstetrics and Gynaecology in BIRDEM Hospital during the period of September 2006 to August 2007. During this study period, 100 pregnant patient with diabetes who attended or admitted at BIRDEM Hospital were studied. Estimation of serum HbA1C level was done in all patient in each trimester. From each patient 5 c.c blood was taken & HbA1C level was measured with the help of enzymatic method. HbA1C level < 6 was considered as normal. .The maternal complications in antenatal period, in postpartum period, during labour & fetal outcome were studied in both cases of controlled & uncontrolled HbA1C level. Result: In this study serum HbA1C level was found raised in uncontrolled diabetic patients. The incidence of vulvovaginitis, preterm delivery and polyhydramnios were significantly high in 2nd and 3rd trimester in raised HbA1C level. The rate of normal vaginal delivery was higher in patient with normal HbA1C leve uncontrolled HbA1C level (17.59% Vs 10.84%, p = 0.01), which statistically significant. Post partum haemorrhage (PPH) was significantly higher in raised HbA1C level than normal (0.00% Vs 22.20%, p =0.01) in NVD and (0.00% Vs 16.22%, p = 0.01) in Caesarean section. Neonatal complications were higher in raised HbA1C level than normal. The incidence of Hypoglycemia (5.88% Vs 38.55%, p = 0.02); Hyperbilirubinemia (11.76% Vs 33.73%, p = 0.03) ; RDS (0.00% Vs 12.05%, p = 0.02); Macrosomia (0.00% Vs 18.07%,p = 0.01) and Birth asphyxia (5.88% Vs. 12.05%, p = 0.04). These differences are statistically significant. Conclusion: There is increasing evidence that the raised level of maternal serum HbA1C in antenatal period is associated with maternal & neonatal complications. By investigating HbA1C level in each trimester, blood sugar control can be done. This study was taken out to evaluate the usefulness of HbA1C for good glycaemic control in diabetic pregnancy. DOI: http://dx.doi.org/10.3329/birdem.v2i1.12358 Birdem Med J 2012; 2(1) 23-28

Author(s):  
Eshrat Jahan ◽  
Rafiul Alam

Introduction: Adolescent childbearing is still a common social and health concern in Bangladesh. Adolescent maternity is causally associated with many poor obstetric complications. Low birth weight is one of the most common problems in adolescent pregnancy and majority of these LBW babies is due to intrauterine growth retardation (IUGR). The aim of the study was to evaluate the obstetric factors and outcomes of adolescent pregnancy having IUGR babies.Methods: This cross-sectional descriptive type of study was conducted at the Department of Obstetrics and Gynaecology, Dhaka Medical College Hospital from the period of January 2012 to June 2012. In this present study, 150 adolescent mothers selected. Sample technique was purposive sampling. Detailed medical, obstetric and neonatal information recorded on a designed data sheet. Data were analyzed using statistical program SPSS.Results: The mean age of all adolescent mothers was 18.14±0.85, while mean age at marriage found 16.24. All the adolescent respondents were married and 9 out of 10 were living with husband (91%). Higher proportion (70%) of Hindu respondents delivered IUGR babies. 60% pregnancies were unplanned, of them, 36% developed IUGR. High proportion of maternal and neonatal complications found among the mothers having IUGR babies. More common maternal complication were severe anemia (65%), fetal distress (56.2%), oligohydramnios (43.8%), pre-¬eclampsia (35.4%), eclampsia (33.3%), PPH (23%), puerperal sepsis (14.6%) and more common neonatal complications were birth asphyxia (96%), hypoglycemia (83%), hyperbilirubinemia (8.3%) and sepsis (8.3%).Conclusions: Adolescent pregnancy complicated with IUGR demonstrated higher proportion of maternal complications like severe anemia, pre-¬eclampsia, eclampsia, oligohydramnios, PPH, and adverse perinatal outcome.


Author(s):  
Niranjan N. Chavan ◽  
Vibhusha Rohidas ◽  
Hanumant Waikule

Background: Abruptio placenta or accidental haemorrhage is one of the obstetrical emergencies and is truly accidental with few warning signs. Present study is planned to study the maternal and fetal outcome in patients of abruption placenta in a tertiary care referral hospital in a rural set up which is helpful to plan management strategies and to decrease mortality and morbidity.Methods: A prospective observational study was conducted at Department of Obstetrics and Gynaecology at tertiary care centre during September 2015 to August 2019. A total of 270 cases of abruptio placenta coming to the labor ward and delivered were included in the study. The information collected regarding maternal and fetal parameters were recorded in a master chart in Microsoft Excel 2010 and analyzed using the statistical package for the social sciences software (SPSS) version 20.0.Results: In the present study there were a total of 29887 deliveries with 270 cases of abruptio placenta, incidence being 0.9%. Bleeding per vagina is the most common presentation (85.6%) followed by pain abdomen (70.7%). Common risk factors for accidental hemorrhage were: Pre-eclampsia (39.6%) and anaemia (32.2%). Rate of cesarean section was 40.7% (n-110) while rate of forceps delivery was 4.8% (n-13). Associated maternal complications include: post-partum hemorrhage (18.9%), DIC (10%), acute renal failure (4.1%) and puerperal sepsis (1.9%) while maternal mortality rate was 1.9%. Low birth weight (<2.5kg) was observed in 74.8% cases while still birth and neonatal mortality rate was 35.2% and 12.6% respectively.Conclusions: Abruptio placenta or accidental hemorrhage is major risk factor for maternal and perinatal morbidity and mortality, thus efforts should be taken to reduce risk factor for abruptio placenta. Strengthening of antenatal care, anticipation and evaluation of associated high-risk factor and prompt management of complication can improve maternal and perinatal outcome in these cases. Abruptio placenta should be managed in centers where there is advanced maternal and neonatal health care facilities are available.


2019 ◽  
Vol 31 (2) ◽  
pp. 50-53
Author(s):  
Most Merina Akhter ◽  
Mst Shaheen Nawrozy ◽  
Abu Hena Mostafa Kamal ◽  
Sahela Jesmin

Background: Postdated pregnancy complicates about 10% of all gestation and is associated with an increase in perinatal mortality and morbidity. This study was designed to observe fetal as well as maternal outcome in the management of postdated pregnancies admitted into Rajshahi Medical College Hospital. Methods: The study was carried out from July 2008 to June 2010. 100 cases of postdated pregnancies were included. Patients’ age, occupation, parity, mode of delivery, the indication of LUCS, fetal & maternal outcomes were recorded in a predesigned questionnaire. Results were expressed as Mean± SD, actual number and percentage of total where applicable. Results: Mean age (±SD) was 21.3 (±5.32) years. 90% were housewives, 5% were in service and 5% were in other occupations. 53% were nullipara, 21% para-2, 18% were para-3, 8% were para-4.57% of the study patients underwent caesarean section and 43% underwent vaginal delivery. Fetal distress (n=34), non-progression of labour (n=19), cord prolapse (n=1) & CPD (n=3) were the causes of LUCS. Regarding fetal outcome, healthy babies were 76%, meconium aspiration 13%, birth asphyxia 11%. Among birth asphyxia, neonatal death was 1% & still born was 2%. Maternal complications at delivery were tear in the genital tract 8%, PPH 5% & wound infection in 4% cases. Conclusion: Here, still-birth rate was 2% (normally about 1 in 3000 deliveries) and perinatal mortality rate is 3% (normally about 2-3 in 1000 deliveries). So, patients should be encouraged to attend regular antenatal check up to prevent postdated pregnancy and its complications. TAJ 2018; 31(2): 50-53


Author(s):  
Caroline T. Henderson Jumbo ◽  
Malachy E. Ayogu ◽  
Habiba I. Abdullahi

Background: Most women will achieve spontaneous vaginal delivery; however, a few will need assistance in form of Instrumental vaginal delivery (IVD). These are employed to shorten the second stage on labour and to minimize the incidence of cesarean section. The aim of the study was to determine the prevalence and outcomes of instrumental vaginal delivery at the University of Abuja teaching hospital.Methods: This was a retrospective study of women who had instrumental vaginal delivery over a 5-year period at the University of Abuja teaching hospital. Data on socio-demographic variables, type of instrumental delivery performed, Apgar scores of neonates delivered, indications and complication were obtained from the labour ward registers and case notes of patients and entered into a proforma and analysed using SPSS software for Windows version 23.Results: Instrumental vaginal delivery (IVD) rate performed for both Vacuum or Forceps) was 0.99%, Forceps delivery was 0.30% and vacuum accounted for 0.69% of all deliveries. The mean maternal age was 27.53±5.5 years and 51 (54.8%) of the parturient were primigravidae, 55 (59.1%) were booked patients.  Delayed second stage of labour (38.7%) was the most common indications for IVD. Maternal complications noted were genital tract laceration 17 (18.3%) and primary post-partum haemorrhage 10 (10.8%). The mean APGAR scores was 6 and 8 in the first and fifth minutes respectively, live births were 85 (91.4%), stillbirths were 7 (7.5%) and one early neonatal death was recorded (1.1%) due to asphyxia as a result of difficult forceps delivery.Conclusions: The IVD rate at UATH is low with good maternal and fetal outcome and preference for vacuum delivery.


Author(s):  
Mamatha Poondru ◽  
R. Kala ◽  
A. Kumar

Background: The aim is to study the prevalence of prelabour rupture of the membranes (PROM), to identify risk factors, mode of delivery, and its maternal and fetal effects.Methods: This was a cross-sectional study conducted in the department of obstetrics and gynaecology at Government Head Quarters Hospital, Cuddalore, Tamil Nadu, with a duration of 6months (January 2020 – June 2020). The study was conducted on 800 pregnant women between 28-42 weeks of gestational age consecutively and those who met the inclusion and exclusion criteria were taken into study.Results: The prevalence of PROM was 27.9% (tPROM 24.6% and PPROM 3.2%). Most of the cases were primigravida (74%). Risk factors associated with PROM were low socioeconomic state (63.2%), urinary tract infection (UTI) (7.2%), vaginal infections (5.8%), and previous history of PROM (3.1%). Most of the patients were delivered by lower segment caesarean section (LSCS) (55.2%), normal vaginal delivery (39.9%) and forceps delivery (4.9%). The most common indication for LSCS was fetal distress (43.9%). Misoprostol induction was associated with more failed induction (2 times) than syntocinon. Maternal complications were post-partum haemorrhage (PPH) (8%), fever (6.7%), wound infection (6.2%), manual removal of placenta (4.4%), and puerperal sepsis (0.9%). Neonatal complications were neonatal intensive care unit (NICU) admissions (14%), respiratory distress syndrome (RDS) (11%), neonatal sepsis (2.6%). Maternal (54.5%) and neonatal (90%) morbidity were more in prolonged PROM >24 hours.Conclusions: Antenatal screening for genitourinary infections especially in cases of the previous history of abortions and PROM should be done. Oxytocin is the preferred method of induction over misoprostol in this study. Active management in term PROM cases can reduce the cesarean section rate.


Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_1) ◽  
Author(s):  
Trixy David ◽  
Ryan Malcolm Hum ◽  
Yen June Lau ◽  
Sue Thornber ◽  
Louise Simcox ◽  
...  

Abstract Background/Aims  The Lupus in Pregnancy Scanning (LIPS) clinic, a joint obstetrics and rheumatology clinic was established in 2010 at Saint Mary’s Hospital, Manchester, UK for women with systemic lupus erythematosus (SLE) and other complex rheumatological conditions. We aimed to describe pregnancy outcomes of women attending this clinic to establish a baseline for future changes aimed at improving the service. Methods  Data were collected retrospectively from electronic records of patients who attended the LIPS clinic at least once between 1st January 2018 and 31st December 2019. Results  Pregnancy outcomes were available in 105/125 (84%) women (Table). The median age [inter-quartile range] was 30.6 years [IQR 27.7 - 33.6] and 40 (38%) were of non-Caucasian background. Sixty-one (58%) had a connective tissue disease (CTD) of whom 36 (59%) had SLE. Other rheumatological diagnoses included inflammatory arthritis, primary anti-phospholipid syndrome (APS) and systemic vasculitis. Anti-Ro was found in 32 (31%) and anti-phospholipid antibodies in 25 (24%). During pregnancy, 65 (62%) received aspirin and 40 (38%) had low molecular weight heparin (LMWH). In the antenatal period, 43 (41%) took steroids, 52 (50%) had conventional disease modifying anti-rheumatic drugs and 8 (8%) received biologics. Active disease in the antenatal period was noted in 14 (13%) women. Regarding pregnancy outcomes (Table), still-births were low (0.95%). The rate of C-sections (45%) and assisted deliveries (19.6%) was comparable to previously published data from similar clinics. P096 Table 1:Pregnancy outcomes over a 2-year period in women attending the LIPS clinic at St. Mary's HospitalPregnancy Outcomen (%)Miscarriage3 (2.9)Deliveries• Live101 (96.2)• Still-birth1 (0.95)Median Gestation (weeks) [inter-quartile range (IQR)]38 [37 - 39]Sex of Neonate• Female57 (56)• Male45 (44)Mode of Delivery• Normal vaginal36 (35.3)• Assisted20 (19.6)• Elective Caesarean Section15 (14.7)• Emergency Caesarean Section31 (30.4)Median Neonatal Birth Weight (grams) [IQR]3137 [2724 - 3428]• Low Birth Weight &lt;2500g15 (15)Maternal Complications (Antenatal and Peri-Partum)• Infection22 (22)• Pre-Eclampsia1 (1)• Post-Partum Haemorrhage56 (55)Neonatal Intensive Care Admission7 (7)Neonatal Complications• Sepsis1 (1)• Congenital Heart Block2 (2)• Prematurity (&lt;36 weeks)39 (38) Conclusion  In this cohort we report a high live birth rate and comparable rates of assisted delivery to similar cohorts. Infection and post-partum haemorrhage are maternal complications that are common, and reflect the complex clinical presentations and therapeutic regimes in these conditions. Overall this specialist clinic achieves favourable maternal and foetal outcomes in this high-risk population. Disclosure  T. David: None. R. Hum: None. Y. Lau: None. S. Thornber: None. L. Simcox: None. I. Bruce: None. C. Tower: None. P. Ho: None.


Author(s):  
Rajib Roy ◽  
Manisha Vernekar

Background: Grand multiparity has been considered as obstetric hazards both to the mother and foetus and thus, viewed with great caution. In present set up grand multiparity is associated with increased likelihood of feto-maternal complications.Methods: The study was conducted to determine the feto-maternal outcome in grand multipara pregnancy.Results: In present study, the prevalence of grand multipara was 0.72% out of 15196 deliveries in the period from September 2010 to august 2012. 79.1% of the grand multipara women belonged to the age group of 31-40 years. A majority of the women were in Para 5. Most of the women had no antenatal care attendance. The highest prevalence of grand multipara women was seen among Muslim community (1.65%). A majority (59.1%) of the women were anemic. Caesarean section rate was 30.0% in our study. Post-partum hemorrhage was the most common complication encountered. 7.0% were macrosomic babies, whereas 8.7% were LBW babies. There were 10 perinatal deaths, birth asphyxia being the most important cause for the perinatal mortality. There were no maternal deaths.Conclusions: Our study demonstrates that, there is increase in antenatal and intra-partum maternal complications like anaemia, hypertensive disorder, preterm labour, increase in the rate of caesarean section, PPH etc., leading to severe maternal morbidity. So, the study concludes that in grand multipara pregnancy, both the woman and the fetus are at a greater risk during pregnancy and labour. This risk can be effectively reduced with good antenatal care and delivery by trained personnel.


2019 ◽  
Vol 26 (09) ◽  
pp. 1491-1499
Author(s):  
Samina Anwar ◽  
Gulmeen ◽  
Shareen Sultan ◽  
Sara Amin

Introduction: GDM is a metabolic disorder defined as its recognition first time in pregnancy. Women with GDM are at increased risk of morbidity and poor fetal outcome. Hence it is essential that early diagnosis and management of disease is carried out to avoid poor maternal and fetal outcome. Objectives: The study was conducted to find out the prevalence of GDM in KHUH following the International Association of Diabetes and Pregnancy Study Groups (IADPSG} Criteria. Following this strict criteria we analyzed the management and its effect on maternal and fetal outcome. Study Design: Retrospective cohort study. Setting: King Hamad University Hospital. Period: Feb 2015-Jan 2016. Inclusion: Patients diagnosed as GDM after 75gm OGTT. Exclusion Criteria: Known diabetic. Patients with unknown diabetic status. Materials and Methods: The study included 230 patients mostly between 24-28 weeks attending the antenatal clinic and some in late third trimester. This study included patient with GDM from - Feb 2015-Jan 2016. For the said year the total number of deliveries were 2747. These patients were given 75 gm OGTT test, by taking first fasting levels and then were given 75 gms of glucose drink and blood levels were taken at 1and 2hrs respectively. The fasting, 1hr and 2hr values were <5.1, 1 hr <10 and 2hrs <8.5. Patient with GDM were managed and followed till delivery to find out the maternal and fetal outcome. Results: The prevalence of GDM in this study was 8%. The C-section rate was 21.8%. The antenatal complications were 7.3% and major complication was hypertension. The postnatal complications were 5.6% and main complication was post-partum haemorrhage (PPH) due to lacerations. Macrosomia was found in 3.4% of cases. The preterm delivery rate was 2.6%. NICU admission was 25.7% and 58.3% of these were admitted for 24 hour observation only. Conclusion: GDM affects maternal and fetal outcome. By following the IADPSG criteria for screening and managing the women helped us in attaining good maternal and fetal outcome.


Author(s):  
Neeraj Sharma ◽  
Deepika Kumari ◽  
Sonal Prasad ◽  
Akanksha Srivastava

Background: A significant rise in triplet pregnancy rate has occurred recently. This rise is of concern, as these infants are frequently reported as a risk factor of adverse outcome. The aim of this study was to retrospectively study the outcomes of triplet births.Methods: A retrospective study was undertaken to analyze the clinical data of all patients with triplet gestation admitted to the labour room of Dr. Baba Saheb Ambedkar Hospital, Delhi to study the maternal and fetal outcomes. Authors retrospectively observed and analyzed the database to examine triplet gestations delivered between January 2014 and December 2018.Results: Over the five-year study period, there were total 44,011 deliveries. Out of these, there were 35 (0.079%) triplet pregnancies. Of all the triplet pregnancies studied 80% resulted from ovulation induction and assisted reproductive technology. The mean gestational age at delivery was 31.6±3.0 weeks, and the mean birth weight was 1,594±460 gm. The most common maternal complications were Preterm labour in 32 pregnancies (92%), anemia in 17 (49%), pre-eclampsia in 11 (31%), post-partum hemorrhage in 8 (22%). Of the total deliveries neonatal complications included Respiratory distress syndrome in 44 (42.2%), Hyperbilirubinemia in 41 (39%), Intrauterine growth restriction in 19 (18.1%). The perinatal mortality rate was 10.5%.Conclusions: Higher order pregnancies are associated with maternal and neonatal complications. These high risk women need more care and the neonates require intensive care and monitoring after birth, most commonly due to prematurity and low birth weight.


2018 ◽  
Vol 30 (1) ◽  
pp. 19-22
Author(s):  
Ummay Salma ◽  
Mahe Jabeen ◽  
Sabiha Shimul ◽  
Dilruba Akhter

Less fetal movement affects perinatal outcome. To examine association between antenatal CTG findings and perinatal outcome in women with less fetal movement. This prospective observational study was conducted in the department of Obstetrics and Gynecology, Kumudini Women's Medical College and Hospital, Mirzapur, Tangail over a period of six months from January 2015 to June 2015. It included 100 pregnant women after 34 weeks of gestation. They underwent a cardiotocogram (CTG) test. Data were collected by face-to-face interview, observation and document review. The mean age of the women was 24.37±4.62 (SD) years and mean gestational age was 38.48±2.15 weeks. In this study, 82.0% of the cases presented at term pregnancy, 42.0% of the women were primi gravida and rest falls between 2nd to 4th gravida. Normal vaginal delivery was in 59.0% cases and rest were undergone caesarean sections (41.0%). Late deceleration with decreased variability was (23.5%) most common. Incidence of low birth weight was 16.0% & macrosomia was 5.0%. Birth asphyxia was found in 52.0% cases, 49.0% needed immediate resuscitation, 35.0% were admitted into neonatal unit and early neonatal death was 8.0%. Birth asphyxia was significantly higher in non-reassuring [37(72.5%)] than reassuring [15(30.6%)] on CTG. Incidence of low birth weight was higher in non-reassuring [11(21.6%)] than in reassuring [5(10.2%)] on CTG (p>0.05). Early neonatal death was more in respondents with non-reassuring [5(9.8%)] on CTG than reassuring [3(6.1%)] on CTG (p>0.05). Twenty six (51.0%) neonatal of the non-reassuring were admitted into neonatal unit whereas only 9 (18.4%) neonatal of the reassuring were admitted into neonatal unit. It can be concluded that CTG may be the first line investigation for ante and intrapartum fetal assessment.Medicine Today 2018 Vol.30(1): 19-22


Sign in / Sign up

Export Citation Format

Share Document