scholarly journals Association of Hypertension and Smoking with Ischaemic Stroke

2013 ◽  
Vol 3 (1) ◽  
pp. 16-18
Author(s):  
K Kirtania ◽  
N Sultana ◽  
S Ahmed ◽  
A Khatun

Hypertension is one of the most important modifiable risk factors for ischemic stroke. Cigarette smoking is a risk factor for atherosclerotic disease. There is a strong relationship between hypertension and cigarette smoking with ischaemic stroke. A case control study was undertaken to see the association of hypertension and cigarette smoking with ischaemic stroke. The study was done from January to December 2009 in the Department of Biochemistry, Dhaka Medical College, Dhaka. A total of 60 subjects were selected as study population. Among them 30 were diagnosed case of ischaemic stroke and 30 were age-and sex-matched control subjects. It was found that 60% patients of case group and 20% respondents of control group were hypertensive and diffrence was significant. Study showed that 56.66% of cases and 53.33% of controls were smoker and the findings were insignificant. The mean duration of smoking was 27.41 ± 2.98 years in cases and 15.63 ± 2.85 years in controls which was significant. The study suggests that hypertension is significantly associated with ischaemic stroke and longer duration of smoking also associated with ischaemic stroke. DOI: http://dx.doi.org/10.3329/bjmb.v3i1.13802 Bangladesh J Med Biochem 2010; 3(1): 16-18

1970 ◽  
Vol 20 (1) ◽  
pp. 12-14
Author(s):  
K Kirtania ◽  
N Sultana ◽  
MZ Hossain ◽  
S Ahmed ◽  
A Khatun

Diabetes mellitus is one of the most important modifiable risk factors for ischemic stroke.Cigarette smoking is a risk factor for atherosclerotic disease. There is a strong relationship between diabetes mellitus and cigarette smoking with ischemic stroke. A case control study was designed to see the association of diabetes mellitus and cigarette smoking with ischaemic stroke. The study was done from January 2009 to December 2009. Sixty subjects were selected as study population which were taken from Dhaka medical college hospital, Dhaka. Among them 30 were diagnosed case of ischemic stroke and 30 were age and sex matched control. The study showed that 33.33% patients of case group and 10 % respondents of control group had diabetes mellitus. It also revealed that 56.66% of case group and 53.33% of control group were smoker and the mean duration of smoking was 27.41 ± 2.98 years in case group and 15.63 ± 2.85 years in control group. The study suggests that diabetes mellitus is significantly associated with ischemic stroke and longer duration of smoking is also associated with ischaemic stroke. Key words: Ischemic stroke; cigarette smoking; diabetes mellitus. DOI: http://dx.doi.org/10.3329/jdmc.v20i1.8565 J Dhaka Med Coll. 2011; 20(1) : 12-14


Author(s):  
B. Khanam ◽  
M. Imran Khan ◽  
Ajay Kumar Singh ◽  
Sumit Solanki ◽  
S.M. Holkar

Background: Few studies have assessed the relation of hyperuricacidemia with the acute coronary syndrome (ACS). This study investigated the association between high uric acid levels with the presence and severity of ACS.  Methods: Three hundred and seventy patients having angiographic evidence of atherosclerosis (CAD + case group) compared to 170 patients with no luminal stenosis (n=110) or with <50% luminal stenosis (n=60) at coronary angiography (CAD – control group). Results: The mean age of the patients was 60 ± 10 years (317 men, 58.7%). Hyperuricacidemia was more likely associated with a trend toward higher vessel scores, indicating a more severe CAD (adjusted OR=1.51, 95% CI=1.09-2.09; P=0.005) in the whole population. A comparison of sex-specific values showed a significant association existed only in men. Conclusions: Asymptomatic hyperuricacidemia may be associated with the presence and severity of ACS. Keywords: Hyperuricacidemia, Severity & Acute Coronary Syndrome.


2020 ◽  
Vol 20 (3) ◽  
pp. 1241-1249
Author(s):  
Mostafa Ahmadi ◽  
Mahbobeh Faramarzi ◽  
Zahra Basirat ◽  
Farzan Kheirkhah ◽  
Mohammad Chehrazi ◽  
...  

Background: Polycystic Ovarian Syndrome (PCOS) is one of the most common causes of infertility in women. Objective: The current study investigated mental and personality disorders in infertile women with and without PCOS. Methods: This case-control study evaluated 400 infertile women who referred to the Infertility Center in Babol city (North of Iran). Participants were categorized into the case group (201 PCOS) and the control group (199 without PCOS). All of the participants completed the Millon Clinical Multi-axial Inventory-III (MCMI-III). Results: The mean scores for clinical personality patterns were significantly higher for six personality disorders (schiz- oid, avoidant, antisocial, depressive, sadistic, and negativistic) and for three classes of severe personality disorder patterns (schizotypal, borderline, and paranoid) in infertile women with PCOS than in women without PCOS. The mean scores for eight clinical disorders (somatoform, manic disorder, dysthymia, alcohol-dependence, drug-dependence, post-trauma stress disorder, major depression, and delusion disorder) were also higher in infertile women with PCOS than in women without PCOS. Conclusion: The scores of many mental and personality disorders are higher in infertile women with PCOS than in women without PCOS. Thus, clinicians should prioritize recognizing and treating psychological problems of infertile women with PCOS. Keywords: Polycystic ovarian syndrome; infertility; personality disorders.


Author(s):  
Neelam Jhajharia ◽  
Madhureema Verma

Background: Pregnancy induced hypertension (PIH) is one of the most common and potential life-threatening complications of pregnancy. This study is aimed to investigate and correlate the hemoglobin, haematocrit, white blood cell count, lymphocytes and platelets in PIH patients in their third trimester.Method: Total 126 subjects were studied out of them 63 patients (case) and 63 healthy pregnant women (control) visiting the Obstetrics and Gynaecology department Jhalawar Medical College, Jhalawar were registered in the study and followed during their pregnancy. Two millilitre of blood sample was drawn aseptically using the 5ml syringe from the median ante cubital vein of all the cases and control participants into EDTA-anticoagulated tubes. Haematological parameter calculated by using Sysmex XN-9100™ Automated Haematology System.Results: The mean hemoglobin level of the case group (8.8206±2.53779) was significantly lower than that of the control group (9.7289±2.47033) (p<0.05). The mean platelet count of the case group (131.4937±62.05999) was significantly lower than that of the control group (324.9683±230.78764) (p<0.05). The mean lymphocytes level of case group (1.2510±0.56369) was significantly lower than that of the control group (1.9295±1.4150) (p<0.05). The mean WBC level of case group (36.3467±119.90635) was significantly high than control group (11.5260±4.83059) (p<0.05). The mean haematocrit level of case group (32.6851±7.29789) was significantly high than control group (30.0424±23.38116) (p<0.05).Conclusion: The mean hemoglobin, mean platelets and mean lymphocytes are lower in PIH patients. The mean WBC and haematocrit are higher in PIH patient. 


2013 ◽  
Vol 21 (2) ◽  
pp. 84-89 ◽  
Author(s):  
Md Manjurul Karim ◽  
Md Abdul Wahab ◽  
Lubna Khondoker ◽  
Md Shirajul Islam Khan

A case-control study conducted in the Department of Dermatology and Venereology of Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2008- December 2010. A total 60 female patients of telogen effluvium attending in outpatient department (OPD) were enrolled in the study with 30 having hair loss considered as case (Group-A) and another 30 females had no history of hair loss were considered as control (Group-B). The study included 60 patients and the mean age were 25.4±7 years ranging from 18 to 42 years in group A and 24.8±5.6 years ranging from 17 to 36 years in group B. Maximum number was found in the age group of 21- 30 years in both groups and nearly three fourth (73.4%) patients were unmarried in group A and 18(60.0%) in group B. Most of the patients were student in both groups, which were 21(70.0%) and 17(56.7%) in group A and group B respectively and majority of the the patients were HSC level in both groups, 15(50.0%) and 14(46.7%) in Group A and Group B respectively. Most of the patients came from middle class, which were 20(66.7%) and 16(53.3%) in group A and group B respectively. The mean serum ferritin were 18.8±8.1 g/L ranging from 4.5 to 36.54 g/L and 36.6±9.9 mg/L ranging from 18.46 to 56.3 mg/ L in group A and group B respectively. The mean Hb level was 11.5±1.4 gm/dl ranging from 8.5 to 14.0 gm/dl in group A and 12.8±1.1 gm/dl ranging from 10.5 to 14.5 gm/dl in group B. The mean difference of Hb level was statistically significant (p<0.05) between two groups in unpaired t-test. It can be concluded that low iron level is associated with telogen effluvium in women. DOI: http://dx.doi.org/10.3329/bjmed.v21i2.13617 Bangladesh J Medicine 2010; 21: 84-89


2018 ◽  
Vol 16 (2) ◽  
pp. 58-61
Author(s):  
Sumit Pandey ◽  
Smita Jha ◽  
Shyam Kumar B.K ◽  
Shyam Kumar B.K. ◽  
Kumar Pokharel

Background: Psoriasis is primarily a chronic skin disease, the course being punctuated by remissions and relapses. Research has shown that hypertension, obesity, heart failure and diabetes are significantly more common in patients with psoriasis. Obesity is associated with severe psoriasis and is reported about twice as frequently among psoriasis patients as in the general population. In recent years many reports have demonstrated an association between psoriasis and metabolic syndrome. Objectives: The aim of this study was to identify the prevalence of obesity in patients with psoriasis and compare it with that of non-psoriatic population. Material and Method: This study is a case control hospital based study conducted in the Department of Dermatology, Venereologyand Leprology of Nepalgunj Medical College Teaching Hospital, Kohalpur between May 2017 to October 2018.Total 56 cases of psoriasis and similar number of healthy age and sex matched controls were enrolled in the study after taking written consent. Detailed history and physical examination was performed with measurement of body mass index which was recorded. Statistical analysis was done using SPSS 20. Result: The results of the study which included 56 patients with psoriasis and 56 subjects without psoriasis. Among them 26 male and 30 female in study population and 25 male and 31 female in control group. The mean age was41.68±19.04 years in study population and 39.46 ±16.27 years in control group. Duration of disease ranged from 2 months to 360months and PASI score ranged from 4.4 to 28.2 with mean PASI score 11.02±5.4. BMI in cases ranged from 16.7 to 34.2 with mean24.3±4.3 and in controls it ranged from 15.5 to 29.1 with mean 21.9±3. Mean BMI was significantly higher in cases than controls. Conclusion: The result of this study supports the significantly higher prevalence of obesity in study population than control group.


2013 ◽  
Vol 29 (1) ◽  
pp. 31-42
Author(s):  
Mohammad Selim Shahi ◽  
Aminur Rahman ◽  
Md Shaheen Wadud ◽  
Ak Takib Uddin Ahmed ◽  
Uttam Kumar Saha ◽  
...  

Background: Several epidemiological studies have identified the association of abnormal ABPI with ischemic stroke. So the goal of this study was to determine the actual relationship of ABPI with ischemic stroke in the context of our country. Materials and Methods: This case control study was carried out in the Department of Neurology, Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh. ABPI was measured by Doppler ultrasound machine of 100 patients who were admitted to the Mitford Hospital during the study period. Among them 50 patients with Ischemic stroke, confirmed by CT/MRI scan of brain were considered as ‘case’ and 50 age- sex matched individuals with one or more vascular risk factors (VRF) but without stroke were considered as ‘control’. Then the results of ABPI were compared between the two groups. Results: Among the 50 patients with ischemic stroke (case group) , 74% had normal ABPI and 26% had ABPI< 0.9; on the other hand among 50 age and sex matched individuals (control group) 90% had normal ABPI and 10% had ABPI <0.9. The difference was statistically significant between two groups (p=<0.05).This association remained significant even after adjustment for potential confounders (age, gender, high BMI, hypertension, diabetes mellitus, hyperlipidemia, smoking, ischemic heart disease and family history) in a multiple logistic regression model. Conclusion: The incidence of low ABPI is significantly higher in ischemic stroke patients than the age- sex matched control. Bangladesh Journal of Neuroscience 2013; Vol. 29 (1) : 31-42


2017 ◽  
Vol 15 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Seyma Kayali ◽  
Fadime Demir

ABSTRACT Objective To assess the association between cigarette smoking and ventricular arrhythmias in adolescents. Novel electrocardiographic parameters –Tp-e interval, as well as Tpe/QT and Tpe/QTc ratios – were used to make this assessment. Methods The study population consisted of 87 subjects aged between 16-19 years. Fifty-one adolescent smokers with no risk of arrhythmia comprised the Smoker Group, and 36 adolescents who had never smoked cigarettes comprised the Control Group. Smokers were defined as patients smoking more than three cigarettes per day, for at least 1 year. Body mass index, systolic, diastolic and mean blood pressures were measured, and electrocardiograms were performed on all subjects. Heart rate, PR and Tp-e intervals, and Tpe/QT, Tpe/QTc ratio were digitally measured. Results Adolescents in Smoker Group had smoked cigarettes for 2.9±1.4 years (range 1 to 6 years). The mean age at starting smoking was 13.8±1.4 years. There were no differences between smokers and Control Group as to baseline clinical variables (p>0.05). The PR, QT and QTc intervals were similar in all groups. Tp-e interval (98.4±12.7ms and 78.3±6.9 ms; p<0.001), Tpe/QT (0.28±0.04 and 22±0.03; p<0.01), Tpe/QTc (0.24±0.03 and 0.19±0.01; p<0.001) ratios were significantly higher in Smoker Group. There were no correlations between years of smoking, number of cigarettes per day, Tpe interval, Tpe/QT or Tpe/QTc ratios. Conclusion Cigarette smoking is associated with risk of ventricular arrhytmogenesis with prolonged Tp-e interval and increased Tpe/QT and Tpe/QTc ratios in adolescents.


2017 ◽  
Vol 2 (3) ◽  
pp. 90
Author(s):  
Azar Pirdehghan ◽  
Abolghasem Rahimdel ◽  
Fariba Yazdanfar ◽  
Mohammadreza Malekjamshidi

Background: Social capital, in general, is mutual relationships, interactions, and networks that emerge among human grouping and is the level of trust formed in the specific group as commitment and social norm. This issue is associated with many mental and physical disorders in the community. The objective of this study was to evaluate the level of social capital in some people with a primary headache in comparison with control group.Methods: This case-control study was performed on 60 patients with a primary headache who referred to one of neurology clinics in Yazd city, Iran, as the case group and 60 subjects without primary headache as the control group that had some similarities with case group in demographic features. Data was collected via social capital questionnaire containing demographic information.Results: The mean score of social capital in the case group was 193.5±30.82 while the mean score of social capital in the control group was 214.1±34.22 (P=0.001) that indicate a significant correlation between social capital level and catching primary headache.Conclusion: Further studies are needed on the effect of social capital on the level of response to treatment in patients with primary headache. It is also suggested to be conducted interventions regarding the impact of social capital on headaches and broader studies with larger scale (urban population) in this regard.


2021 ◽  
Vol 8 (9) ◽  
pp. 1451
Author(s):  
Sayeeda Anwar ◽  
Zohora Jameela Khan ◽  
Naznin Akhter ◽  
Fatema Farzana ◽  
Zannatul Shormin ◽  
...  

Background: The COVID-19 pandemic has caused devastating diseases worldwide both in children and adults. Subsequently, a serious and novel pediatric condition called children's multisystem inflammatory syndrome (MIS-C) has emerged and it is important to understand the temporal association between MIS-C and COVID-19. In hyper inflammation syndrome following COVID-19, MIS-C, and multi-organ involvement were documented in the pediatric population. The main goal of this study was to assess the relation of the MIS-C with COVID-19.Methods: This single-center case-control study was conducted at Dhaka medical college hospital (DMCH), Dhaka, Bangladesh. Among 1715 studied population, 227 COVID-19 positive pediatric patients were included in this study. Among them 103 had features of MIS-C in the case group and 124 were in the control group without MIS-C.Results: There were 6% MIS-C patients with COVID-19. The prevalence of male patients was observed in this study. The mean age of the patient group with MIS-C was 7.8±3.12 years. The frequencies of fever 93.3 vs 67.7%, p=0.045; conjunctivitis 75.6% vs 53.2%, p=0.039; rash 47.3% vs 16.1%; arterial hypotension 71.3 vs 12.9%, p=0.058 hypoxemia 80.4% vs 57.2%, p=0.049 and other features were significantly higher in MIS-C patients than the patients without MIS-C. More patients with MIS-C had cardiac abnormalities in our study.Conclusions: MIS-C is an emerging clinical entity and this study was focused on the cases of MIS-C in the pediatric population withCOVID-19. In patients with atypical clinical findings and complaints about COVID-19, MIS-C-like illnesses should be considered.


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