scholarly journals Incidence of post operative surgical site infection in thyroid surgery following single dose of prophylactic antibiotic

2020 ◽  
Vol 22 (1) ◽  
pp. 15-20
Author(s):  
Md Abul Hossan ◽  
Md Ariful Islam ◽  
Tapas Chakraborty ◽  
Firoz Ahmed Khan ◽  
Md Mozharul Islam

Surgical site infection after thyroid surgery is a less common incidence. Prophylactic antibiotic before surgery and empirical antibiotic therapy after surgery is a common practice in our country. But international guidelines do not suggest antibiotic in clean surgical procedure. Aim: To compare the incidence of surgical site infection after thyroid surgery with and without empirical antibiotic therapy. Method: It was a cross sectional study, done from July 2010 to December 2010 in 3 medical college hospitals in Dhaka city. Total 100 cases were included in this study, 50 cases for study in which only single prophylactic antibiotic used half an hour before operation, 50 cases for control in which 7 days antibiotic used per orally in addition to prophylaxis. Result: Among 100 cases male were 24 & female 76 (M: F= 1:3.2). Oldest patient was 56 yrs & youngest 21yrs. 47% patient operated for solitary thyroid nodule, 35% multinodular goiter & only 6% diffuse goiter. 47% patient was done hemithyroidectomy & only 7% total thyroidectomy. All the operations were completed within 2 hours where 40% within one hour. No surgical site infections were found in both study and control cases. Conclusion: There is no statistical difference between routine antibiotic use and no use of antibiotic after thyroid surgery. Bangladesh J Otorhinolaryngol; April 2016; 22(1): 15-20

2021 ◽  
Vol 62 (5) ◽  
Author(s):  
Tran Quynh Anh ◽  
Bui Van Tung ◽  
Nguyen Tuan Tai ◽  
Chu Van Thang ◽  
Dang Duc Hoan ◽  
...  

Objective: Description of knowledge on prevention of surgical site infections (SSIs) among medical staff in Son Tay general hospital, 2021 and some related factors.Method: A cross-sectional study was conducted on 151 medical staff.Results: The rate of medical staff with fully knowledge of SSI prevention is 36.42%, in which the rate of doctors is 38.3% and of nurses is 35.58%. Age group ≥30 (OR=2.82; 95%CI: 1.12 – 7.13);Department of Surgery (OR=13.61; 95%CI: 5.14 – 35.98); working year ≥10 (OR=2.54; 95%CI: 1.26 – 5.11) and number of patients cared for/day <8 (OR=3.43; 95%CI: 1.26 – 9 ,34) are factorsrelated to the knowledge of medical staff about regarding SSIs.Conclusion: The medical staff’s knowledge of surgical site infection prevention is suboptimal; relevant factors should be considered when conducting ongoing training in the prevention of surgical site infections in hospitals.


Author(s):  
Christie M Bertram ◽  
Michael Postelnick ◽  
Christian M Mancini ◽  
Xiaoqing Fu ◽  
Yuqing Zhang ◽  
...  

Abstract Alternative antibiotics for surgical prophylaxis are associated with increased adverse events and surgical site infection compared to cefazolin. In a sample of perioperative inpatients from 100 hospitals in the United States, cefazolin was 9-fold less likely to be used in patients with a documented β-lactam allergy whereas clindamycin was 45-fold more likely.


2015 ◽  
Vol 52 (2) ◽  
pp. 83-87 ◽  
Author(s):  
Álvaro Antônio Bandeira FERRAZ ◽  
Luciana Teixeira de SIQUEIRA ◽  
Josemberg Marins CAMPOS ◽  
Guido Correa de ARAÚJO JUNIOR ◽  
Euclides Dias MARTINS FILHO ◽  
...  

Background The incidence of surgical site infection in bariatric patients is significant and the current recommendations for antibiotic prophylaxis are sometimes inadequate. Objective The aim of this study was to analyze the effect of three prophylactic antibiotic regimens on the incidence of surgical site infection. Methods A prospective, cross-sectional study was conducted between January 2009 and January 2013 in which 896 Roux-en-Y gastric bypasses were performed to treat obesity. The study compared three groups of patients according to the perioperative antibiotic prophylaxis administered intravenously and beginning at anesthesia induction: Group I consisting of 194 patients treated with two 3-g doses of ampicillin/sulbactam; Group II with 303 patients treated with a single 1-g dose of ertapenem; and Group III with 399 patients treated with a 2-g dose of cefazolin at anesthesia induction followed by a continuous infusion of cefazolin 1g throughout the surgical procedure. The rate of surgical site infection was analyzed, as well as its association with age, sex, preoperative weight, body mass index and comorbidities. Results The rates of surgical site infection were 4.16% in the group treated prophylactically with ampicillin/sulbactam, 1.98% in the ertapenem group and 1.55% in the continuous cefazolin group. Conclusion The prophylactic use of continuous cefazolin in surgeries for morbid obesity shows very promising results. These findings suggest that some prophylactic regimens need to be reconsidered and even substituted by more effective therapies for the prevention of surgical site infections in bariatric patients.


2020 ◽  
Vol 41 (S1) ◽  
pp. s336-s336
Author(s):  
Adriana Oliveira

Background: Surgical site infection (SSI) stands out among healthcare-related infections as one of the most important globally due to its associated morbidity and mortality. However, it is well known that the transoperative period is recognized as one of the most critical moments for the prevention of SSI. Objective: We evaluated the knowledge of the operating room (OR) nurse coordinators regarding SSI prevention measures. Methods: We conducted a cross-sectional study in 30 large hospitals in the state of Minas Gerais, Brazil, from February 2018 to April 2019. Data were collected through interviews with OR nurse coordinators. Results: Administration time of prophylactic antibiotic administered between 30 and 60 minutes prior to surgery was reported by 84% of the professionals and the suspension of this agent in the first 24 hours was reported by 47.8%. Preoperative hair removal within the operating room was mentioned by 60% of respondents and 36.7% mentioned using a razor. The Safe Surgery program of the WHO was unknown to 6.7% of nurses. Among those who knew about it, 20.8% stated that there was no surgical site demarcation. Presentation of the surgical team occurred before the beginning of the procedure in only 53.3% of the institutions. Patient surveillance for SSI was reported by 93.3% of respondents, but the criteria adopted for the diagnosis of SSI were unknown, even though SSI rates were given for 90% of services, predominantly via meetings (53.5%). Conclusions: The knowledge of nurses related to the prevention of SSI was not satisfactory, pointing to the need for immediate efforts in education and awareness programs. Such programs may facilitate changes in practice through the recognition of surgical patient risk by these professionals, thus leading to better planning and practice during the trans-operative period.Funding: NoneDisclosures: None


2020 ◽  
Vol 3 (1) ◽  
pp. 5
Author(s):  
Nabilah Puspa Utami ◽  
Dyah Fauziah ◽  
Muhtarum Yusuf

Introduction: Surgical site infection (SSI) often occurs in operation. SSI frequently only affects the superficial tissues, but some more serious infections can affect the deeper tissues or other parts of the body. The majority of SSIs become apparent within 30 days of an operative procedure, when a prosthetic implant is used, SSI may occur several months after the operation. To minimize surgical site infection occurrence, prophylaxis antibiotic is often used. The aim of the study is to evaluate the use of perioperative antibiotics for otorhinolaryngology surgery in third referral hospital in Surabaya.Methods: This study was a retrospective cross-sectional method through the medical record of patients cases from December 2017 to January 2018. All data about sex, age, diagnosis, wound classification, surgical intervention including ICD 9 CM codes, and antibiotics regiments are presented descriptively.Results: Of total 68 patients, 42 (61.8%) were male and 46 (61.8%) were aged 18-65 years old. The most common type of operation was clean surgery 52 (76.5%). The most common prophylactic antibiotic was cefazoline 25 (96.6%). Conclusion: Most of the performed surgery was clean surgery. The use of perioperative antibiotics in most performed operations was in accordance with existing literature. The most widely used prophylactic and therapeutic antibiotic was cefazoline and ceftriaxone, respectively. Further research about risk factor of SSI, the use of prophylaxis antibiotic, and bacterial profile with more samples is needed for more accurate results.


2020 ◽  
Vol 9 (1) ◽  
pp. SG01-SG03
Author(s):  
Ajeet Kumar ◽  
Bhartendu Kumar ◽  
Sunil Kumar

Background: Surgical site infections (SSI) are an important post-operative complication. Knowledge about its risk factors is essential. The present study was conducted to find the profile of surgical site infection among patients admitted in surgical ward of SKMCH, Muzaffarpur.Subjects and Methods:The present cross-sectional study included 322 patients undergoing surgery. Clinical details, onset of SSI and microbiological profile were noted.Results:Mean age of the cases was 43.7 years. 61.2% of these were males. 11.8% of the cases suffered from surgical site infection. Of the emergency surgeries, 20.2% had SSI while 8.1% elective surgery cases had SSI. 36.1% of the cases with dirty wound had SSI while only 5.2% of the cases with clean wound had such infection. S. aureus was the most common organism isolated (57.9%) followed by Pseudomonas (39.5%) and Klebsiella (23.7%).Conclusion: Incidence of SSI is higher in cases of emergency surgery and in dirty wounds.


2019 ◽  
Vol 6 (3) ◽  
pp. 843
Author(s):  
K. Saravanan ◽  
T. Uma Maheswari

Background: Surgical site infections (SSI) are one of the most common postoperative complications leading to increased morbidity which also an important factor of increased hospital stays and increased healthcare cost. The use of prophylactic antibiotics may benefit the patients in preventing the surgical site infection. Aim of the study was to study the single dose prophylactic antibiotic use in preventing surgical site infection in elective surgery.Methods: Patients were included from the list of elective surgery. Patient with comorbid was excluded. The patient was handled as per NICE guideline for prevention of surgical site infection and treatment 2017. Prophylactic antibiotic injection cefuroxime 1500mg administered intravenously 30 minutes before surgery, at the site of the incision.Results: In 110 patients included in the study, 46% of patients were in 35 to 45 years, male were higher in number. 20% of patients underwent hernioplasty followed by cholecystectomy 18.3%. 9% of SSI was recorded in this study. 4 cases in cholecystectomy, 3 cases in hernioplasty, each 1 case in appendicectomy, Hydrocele and ventral hernia mesh repair. The most common bacteria isolated from the samples were Staphylococcus aureus.Conclusions: In uncomplicated surgeries, single dose antibiotics before 30 minutes of surgery may benefit in preventing SSI.


2021 ◽  
Vol 8 (9) ◽  
pp. 2519
Author(s):  
Mohammad Jayedul Islam ◽  
Rasell Md ◽  
Krisna Rani Majumdar ◽  
K. M. Shaiful Islam ◽  
Abu Khaled Muhammad Iqbal

Background: Surgical site infections (SSIs) has been reported to be one of the most common causes of nosocomial infections which accounting for 20% to 25% worldwide. Despite recent advances in aseptic techniques, SSIs continue to be a major source of morbidity and mortality in developing countries and continue to represent about a fifth of all healthcare-associated infections. The aim of the study was to assess the pattern and etiological factors of surgical site infection among the patients who had undergone in surgery.Methods: This study was a cross-sectional study conducted at the department of surgery in Sir Salimullah Medical College and Mitford Hospital (SSMC and MH), Dhaka, Bangladesh from August 2017 to July 2018. Total 160 admitted patients who had undergone surgical procedures during the study period were assessed and interviewed.Results: The mean±SD age of the participants was 51.79±11.30 SD years. About 59% were male and 41% were female. Most of them came from rural areas (61%).  Surgeries were done in different indications and 21% developed SSI. Of all SSIs, 73% were superficial and 27% were deep infections. The most common organism involved in SSI was S. aureas (42.4%), followed by E. coli (27.3%), P. aeruginosa (12.1%), bacteroids (12.1%), and Klebsiella spp. (6.1%). Meropenem was the most sensitive drug followed by Ceftriaxone. Gentamycin showed cent percent sensitivity on the gram-negative organisms.Conclusions: The incidence of SSIs was found in about one-fifth of the post-surgical cases, where Staphylococcus aureus was the most prevalent organism. 


2020 ◽  
Vol 15 (2) ◽  
Author(s):  
Muhammad Hasan Wattiheluw ◽  
Fauna Herawati ◽  
Setiasih Setiasih ◽  
Rika Yulia

Infectious diseases are one of the top ten causes of death in the world. Antibiotic therapy is administered for infectious diseases, but if bacteria are exposed to antibiotics continuously, then the bacteria are able to adapt to the medication, thereby resulting in antibiotic resistance. This condition results in an increase in mortality, long hospitalization period, and increased cost of antibiotic therapy and health services. Adherence to using antibiotics may be influenced by knowledge and beliefs about them. This study aimed to understand correlation between knowledge and belief with adherence to antibiotic use at a private hospital in Sidoarjo. This cross-sectional study, the data collected in three months period, was conducted with a questionnaire for assessment knowledge and belief. A pill count method was applied for assessment adherence to using antibiotics prescribed by doctors. The study results show that knowledge of the respondents was adequate for 76 people (69.7%), belief was adequate for 74 people (67.9%), and adherence to antibiotic use for 79 people (72%). Regression analysis showed that the variable that significantly influenced the adherence of patients in using antibiotics was perceived threat (p-value = 0,029). Sex, age, education, income, occupation, and marital status have no contribution to antibiotic knowledge, belief, and adherence.


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