scholarly journals Effect of Dyslipidaemia on Arrhythmia in Diabetic Patients

2017 ◽  
Vol 46 (1) ◽  
pp. 20-24
Author(s):  
Shabnam Jahan Hoque ◽  
Aparna Rahman ◽  
Md Babul Miah ◽  
Md Zahid Alam ◽  
SM Rezaul Irfan ◽  
...  

Dyslipidaemia is an important risk factor for cardiovascular morbidity and mortality. This cross-sectional study aims to find out the effect of dyslipidaemia on arrhythmia in diabetic patients. A total of sixty (60) diabetic patients, 31 were male and 29 were female, mean age was 59.58±11.38 (range 40 to 84) years with arrhythmia were selected at the department of Cardiology at Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder(BIRDEM) General Hospital, Dhaka over a period of six months from January to July 2014. All the patients were accomplished with 24 hours Holter ECG monitoring, among them 40 were dyslipidaemia with mean age 60.7±13.1years and 20 were without dyslipidaemia with mean age 58±10.3 years (p-value was 0.424). Mean pulse, systolic and diastolic blood pressure were 78±15 (range 55-98) beats/min, 132±20 (range 90-180) mm of Hg and 79±8 (range 60-100) mm of Hg respectively. Mean maximum and minimum heart rate were 114±22 and 57±14 beats respectively. Mean cholesterol level was 222.58±55.51 mg/dl, mean triglyceride 241.26±98.81 mg/dl, LDL 135.53±35.61 mg/dl and HDL 41.46 ±15.46 mg/dl. Mean supraventricular beats in 24 hours was 12031± 4201 with dyslipidaemia and 8522± 2099 without dyslipidaemia which was statistically significant. Mean ventricular beats in 24 hours was 13472 ± 4872 with dyslipidaemia and 8754 ± 2689 without dyslipidaemia which was also statistically significant. Arrhythmia was found more common among diabetic patients having dyslipidaemia than without dyslipidaemia.Bangladesh Med J. 2017 Jan; 46 (1): 20-24

2021 ◽  
Vol 5 (5) ◽  
pp. 01-05
Author(s):  
Gninkoun Comlan Jules ◽  
Fanou Joseph Soglo ◽  
Alassani Adebayo Sabi Cossi ◽  
Djrolo François

Background Diabetes mellitus is well known as a major risk factor for cardiovascular diseases. Cardiovascular autonomic neuropathy is one of the diabetes complications that has a major impact on cardiovascular morbidity and mortality in patients with diabetes. Aim : To determine the prevalence of cardiovascular autonomic neuropathy in patients with diabetes attending the diabetic center in Cotonou and to identify its risk factors. Materials and Methods : It was a cross-sectional study. Cardiovascular autonomic neuropathy was identified using deep breathing test, standind test and the blood pressure response to standing test (orthostatic hypotension). Chi square test was used for statistical analysis and différence was considered significant when p<0.05. Results : A total of 405 subjects were included in the study. Their mean age was 53.67±11,68 years and the mean diabetes duration was 6.66 years. The prevalence of cardiovascular autonomic neuropathy was 65.9%. Regarding the severity of the complication in neuropathic patients, 51.7% of them had an early neuropathy, 41.2% have presented a moderate neuropathy and 7.1% have presented a severe neuropathy. Factors associated with cardiovascular autonomic neuropathy were age of patients (p = 0.0002), diabetes duration (p = 0.0012), hypertension (p =0.0015), dyslipidemia (p = 0.027) and high pulsed blood pressure (p = 0.032) Conclusion : Cardiovascular autonomic neuropathy is a very frequent complication of diabetes mellitus. Unfortunately this complication of diabetes is not often explored in the patient's follow-up examination. As this complication is recognised to be associated with high cardiovascular morbidity and mortality, systematic screening can be recommanded in patients with long duration of diabetes or presenting an other cardiovascular risk factor.


2014 ◽  
Vol 37 (8) ◽  
pp. 779-784 ◽  
Author(s):  
Hiromi Mori ◽  
Isao Saito ◽  
Eri Eguchi ◽  
Koutatsu Maruyama ◽  
Tadahiro Kato ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Yun Zhang ◽  
Qiong Wang ◽  
Quanzhong Li ◽  
Ping Lu

Objectives. The concept now emerging is that higher thyroid-stimulating hormone (TSH) and lower thyroid hormone levels within the euthyroid range may adversely affect atherosclerosis. The present study aimed to investigate the potential associations between thyroid parameters and hyperhomocysteinaemia in a cohort of euthyroid diabetic subjects.Material and Methods. Two hundred and seventy-three euthyroid diabetic subjects (167 males and 106 females) were consecutively recruited in this cross-sectional study. Clinical and biomedical data was collected.Results. TSH level was higher in females than males. Compared to normal-homocysteine group, hyperhomocysteinaemia group was more likely to be elderly, males, with longer diabetes history, and with lower diastolic blood pressure. Free thyroxine (FT4) level was lower in hyperhomocysteinaemia group than in normal-homocysteine group; however, it was not statistically significant. Adjusted for age, sex, body mass index, duration of diabetes, blood pressure, fasting glucose, total cholesterol, and triglyceride in logistic regression analyses, hyperhomocysteinaemia was significantly correlated with FT4 (P=0.021). No significant association was found with TSH or free triiodothyronine. When analyzed in subjects with TSH < 2.5 uIU/mL separately, we got similar results.Conclusions. In conclusion, we identified a relation between hyperhomocysteinemia and FT4 in a group of euthyroid diabetic patients.


2021 ◽  
Vol 12 (2) ◽  
pp. 327
Author(s):  
Ikit Netra Wirakhmi ◽  
Iwan Purnawan

AbstrakLatar belakang: Sampai saat ini, hipertensi masih merupakan tantangan besar di Indonesia. Kepatuhan pasien dalam menggunakan obat berpengaruh terhadap keberhasilan terapi pengobatan. Adanya ketidakpatuhan pasien hipertensi dalam minum obat dapat memberikan efek negative yang sangat besar, seperti munculnya komplikasi. Tujuan: Mengetahui hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi di Puskesmas Karangjambu Kabupaten Purbalingga. Metode: Desain penelitian ini adalah cross sectional study. Responden dalam penelitian ini adalah pasien hipertensi di Puskesmas Karangjambu Kbupaten Purbalingga. Sampel diambil menggunakan teknik accidental sampling dengan jumlah 86 responden. Data dikumpulkan pada bulan Mei 2021 menggunakan kuesioner 8 – Item Morisky Medication Aderence Scale (MMAS – 8) dan pengukuran tekanan darah secara langsung. Hasil: Penelitian ini menunjukkan bahwa Sebagian besar responden adlaah perempuan (86%), sebgain besar berada pada kategori tingkat kepatuhan sedang (47%) dan pada kategori hipertensi tahap 2 (63%). Uji stastistik didapatkan nilai p value 0.901 menunjukkan bahwa tidak ada hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi. Kesimpulan: Tidak ada hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi AbstractBackground: In Indonesia, hypertension is still a major problem. Adherence to treatment is critical for hypertension patients' long-term health and well-being. Adherence are required for hypertension therapy to be effective, and altering these patients' behavior has the greatest potential for improving hypertensive control. Objectives: To explore the relationship between medication adherence and blood pressure in hypertension patients. Methods: We used the cross-sectional study. This research sample was hypertension patients at Karangjambu Health Centre Purbalingga Regency. We included 89 respondents by accidental sampling technique. We collected the data by questionnaire. The Gamma & Sommers’d test was performed to analyze the data. Results: This research showed that that the majority of respondents were women (86%), the moderate category had the highest level of adherence (47%) and the most respondents suffer from hypertension stage 2 (63%). The statistical test result of 0.910 suggested that there was no relationship between medication adherence and blood pressure in hypertensive patients. Conclusions: There was also no significant between medication adherence and blood pressure. 


Author(s):  
Mahboube Ahmad Nazari ◽  
Hamid Oliaee ◽  
Reza Bidaki ◽  
Mohammad Hossein Sorbi

Objective: Diabetes is one of the chronic diseases which can be accompanied with suicide. The study was conducted to assess and compare the prevalence of suicidal ideation in diabetic patients receiving insulin and oralmedication treatment. Materials and Methods: In this cross-sectional study, 2000 patients with diabetes supported by diabetes institute of Rafsanjan in 2017. After giving conscious permission, the patients filled in a demographic checklist and Beck suicidal ideation questionnaire. The data were analyzed using SPSS-16. Results: Prevalence of suicidal ideation in patients with diabetes receiving insulin was 3.2% (n=32) and in people receivingoral medication treatment was 3.1% (n=31). There were no association between suicidal ideation and the method of diabetes treatment. Suicidal ideation was more prevalent in illiterate people; however, no significant relationship was seen between suicidal ideation and education level. Also, there was no significant relationship between marital status and suicidal ideation. There was no relationship between suicidal thoughts and the method of treatment ( P -value: 0.05). Conclusion: Suicidal ideation is more prevalent in diabetic patients, but there were not differences between two group under insulin therapy and oral anti-diabetic agents.


Author(s):  
Jafer Siraj ◽  
Turi Abateka ◽  
Oliyad Kebede

Introduction: A number of medications have been demonstrated to lower blood glucose. However, current-day management has failed to achieve and maintain the optimal glycemic level for diabetic patients. Patients’ non-adherence is among the most contributing factors. Therefore, the aim of this study was to explore the prevalence of non-adherence to anti-diabetic medications and associated factors. Methods: A hospital based cross-sectional study was conducted from November 2020 to January 2021. A systematic random sampling technique was used. Data were collected by structured questionnaire adapted from different literatures. Then, data were entered into SPSS version 25 and analyzed. To determine the association of dependent and independent variables, multiple logistic regression was done. P-value <.05 was considered statistically significant. Results: A total of 275 study participants were interviewed with a response rate of 100%. From this 53.8% were females, 59.3% were in the age group of 41-60 years, 35.3% were college/university graduates and 79.3% were not using social drugs. One hundred eighty-seven (68%) of them were adherent to their anti-diabetic medication. Factors found to be significantly associated with anti-diabetic medication adherence were age >60 years (AOR = .276, 95% CI = .124-.611) attending higher education (AOR = 6.203, 95% CI = 1.775-21.93), retired (AOR = 7.771, 95% CI = 1.458-41.427), housewife (AOR = 7.023, 95% CI = 1.485-33.215), average monthly income 1001birr-2000 birr (AOR = .246, 95% CI = .067-.911) and social drug use (AOR = 3.695, 95% CI = 1.599-8.542). Forgetfulness, not affording, side effects, misunderstanding of instructions, and poly-pharmacy were identified reasons for non-adherence. Conclusions and Recommendations: Patients’ adherence to anti-diabetic medications in the current study is sub-optimal. Age, monthly income, level of education, occupational status, and social drug use were associated with adherence. Forgetfulness, not affording, and side effects were reasons identified to contribute to non-adherence. Therefore, adherence counseling, use of alarms, and the way to mitigate non-affordability, including anti-diabetic medications into a program drug should be considered.


2016 ◽  
Vol 2 (3) ◽  
pp. 458-463
Author(s):  
AHM Mahmudur Rahman ◽  
Lutful Haque Saran ◽  
Md Mamun Ur Rashid ◽  
Adnan Taher

A study way carried out in Dhaka city to find out the management and treatment patterns of diabetic patients those having blood pressure complications. It was a cross sectional study of 150 patients by using self administered survey questionnaire and founded data was analyzed and described. In this study, it is found that almost all of the patients (92%) were from Dhaka and just were a few those were outsider but came as referred patients. The male and female percentages were accordingly 64.67% and 35.33% and among those diabetes patients 47.33% had hypertension and 10.66% had hypotension and most of them (74%) check their diabetes monthly. Among those patients 79.33% patients were prescribed only drugs while 17% patients were prescribed to change their routine only and 4% were prescribed both (drug and routine). Most of the diabetes patients having blood pressure complicacy were prescribed only drugs which is very significant and those are going to do further research in this aspect will be benefited by getting this information.Asian J. Med. Biol. Res. September 2016, 2(3): 458-463


2017 ◽  
Vol 4 (6) ◽  
pp. 2205
Author(s):  
Madhivanan S. ◽  
Harikrishnan E. ◽  
Kumarasamy K.

Background: Blood pressure measurements in childhood are an important clinical examination. Present study was done to evaluate the normal range of blood pressure (BP) in children aged 6-12 years and to find its relationship with regard to age, sex, height and weight criteria and comparing the values with the available standards.Methods: This prospective cross-sectional study was done in primary and middle schools of Chennai from January 2016 to May 2017. Three readings of blood pressure were recorded for each subject and were correlated with age, gender, socioeconomic status and anthropometry. Data was analysed on SPSS 20.0. P value of <0.05 was considered significantResults: A total of 2002 children (1026 boys, 976 girls) of age between 6-12 years were examined over 18 months. There was an upward trend in both systolic (r = 0.437, P<0.001) and diastolic BP (r = 0.386, P <0.001) with age. There was no statistically significant difference in mean systolic and diastolic BP with gender (P = 0.10), weight (P = 0.10) and height (P = 0.10). There was a statistically significant difference between the mean systolic and diastolic BP between low and high socio-economic groups (P <0.0001). The proportion of children with hypertension was 9.54% with a slight female preponderance.Conclusions: Blood pressure measurement in children is pivotal in clinical examination. It shows a linear relationship with age and varies across socio-economic status. Periodic recording of BP would enable identify hypertension at an early age.


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