scholarly journals Risk factor Analysis and Angiographic Profiles in First 228 Cases Undergone Coronary Angiography in Cardiac Cath Lab of Dhaka Medical College Hospital

1970 ◽  
Vol 3 (2) ◽  
pp. 122-125 ◽  
Author(s):  
AEMM Islam ◽  
M Faruque ◽  
AW Chowdhury ◽  
HIR Khan ◽  
MS Haque ◽  
...  

Background: Coronary artery diseases are one of the major challenges faced by cardiologists. Control of certain risk factors for CAD is associated with decrease in mortality and morbidity from myocardial infarction and unstable angina. So, identification and taking appropriate measures for primary and secondary prevention of such risk factors is, therefore, of great importance. This retrospective study was carried at the newly set up cath lab in Dhaka Medical college. Materials and Methods: Total 228 consecutive case undergone diagnostic coronary angiogram from 10th January 2007 to31st January 2009 out of which 194(80%) were male and 34 (20%) were female. In both sexes most of the patients were between 41 to 60 years of age. Risk factors of the patients were evaluated. Results: In females commonest risk factor was Diabetes (58.8%) followed by dyslipidaemia (35.3%). In males commonest risk factor was hypertension (30.9%) followed by smoking (29.9%) and diabetes (28.3%). In males 44.3% patients presented with acute myocardial infarction followed by stable angina (43.3%); but in females stable angina was the commonest presentation (50.0%) followed by myocardial infarction (38.2%).CAG findings revealed that in males 33.5% had double vessel disease 26.8% followed by single vessel 26.8% and multivessel disease 25.3%. In females normal CAG was found in 35.5% followed by double vessel 23.5%, multivessel 20.6% and single vessel 20.6%. On the basis of CAG findings; in males 41.8% patients were recommended for CABG, followed by PTCA & stenting 26.3% and medical therapy 30.0%; where as in females 55.9% were recommended for medical therapy , followed by CABG 32.4% and PTCA & stenting11.8%. Conclusion: The commonest presentation of CAD was 4th and 5th decades in both sexes. Diabetes and dyslipidaemia were more common in females whereas hypertension and smoking were more common in males. Myocardial infarction and stable angina were most common presentation in both sexes though in males myocardial infarction was more common. In males the angiographic severity of CAD was more and they were more subjected for CABG in comparison to females. Key words: Risk factors; Coronary angiography. DOI: http://dx.doi.org/10.3329/cardio.v3i2.9179 Cardiovasc. J. 2011; 3(2): 122-125

1970 ◽  
Vol 4 (1) ◽  
pp. 53-57 ◽  
Author(s):  
PK Das ◽  
S Ghafur ◽  
B Bhattarcharjee ◽  
A Dey ◽  
AL Mollah ◽  
...  

Background: Coronary artery disease (CAD) is now an emerging epidemic in developing countries including Bangladesh. Younger people are being affected here more and more. Young individuals with acute myocardial infarction (AMI) may have unique presentation, risk factor, angiographic profile and outcome which may have an influence on the preventive strategies. This study is an attempt to investigate the same. Methods: Young patients (aged d” 40 yrs) with AMI admitted to the coronary care unit of Chittagong Medical College Hospital over a period of one year were included in the study. Assessments of the patients were done with clinical history, physical examination and systemic evaluation. Location and types (STEMI, NSTEMI) of myocardial infarction were determined by ECG and serum troponin- 1 assay. Blood for glucose and lipid profile was drawn within 24 hours of admission. High sensitivity testing for C-reactive protein (hs CRP) was done in all patients. Coronary angiography was done within 6 weeks of hospital discharge. Results: A total of 83 Patients with age d” 40 years were included .Age range were 21-40 years (34.21 ± 5.07 yrs). There were 71 male (85.5%). Male: female ratio was 5.9:1. Most of the young AMI patients presented lately to the hospital. Majority of these patients were thinly built, came from urban or semiurban areas, engaged in heavy physical activities and belonged to lower socioeconomic group. A positive family history of CAD was present in 18 patients (28.68 %). Smoking was the most prevalent risk factor followed by a raised serum triglyceride or low high density lipoprotein (HDL). A raised hs CRP was present in 47 patients (49.39%). The overall in hospital mortality was only 3.61 %. Coronary angiography done in 38 patients revealed single vessel disease in the majority. Conclusion: The study focuses our attention to the rising incidence of AMI in young individuals who are less prone to CAD. Early detection of AMI and timely intervention needs high index of suspicion in this age group. These young patients have got low BMI High TG, Low HDG High hs CRP & habit of smoking. Avoidance of smoking, controlling high TG and/or low HDL may reduce incidence of AMI among young patients. Use of high dose of statin at an early age in young persons with raised CRP may be considered. Keywords: Myocardial infarction; Young. DOI: http://dx.doi.org/10.3329/cardio.v4i1.9390 Cardiovasc. J. 2011; 4(1): 53-57


1970 ◽  
Vol 18 (1) ◽  
pp. 37-42
Author(s):  
Abdur Rahsid ◽  
Md Mofakkurul Islam ◽  
Md Rafiqul Islam

Myocardial infarction (MI) is the common form of coronary heart disease. A large number of modifiable risk factors had been identified. This descriptive study was done to observe selected risk factors among the MI patients admitted in CCU of cardiology department of Rajshahi Medical College Hospital in the month of March to June 2005. Data were collected from 200 patients using a closed end questionnaire. Anterior, inferior and non-Q types of MI occupied the major (25%, 24.5% & 20.5%) portion of study subjects, CK-MB level was high in all MI patients, majority (57.5%) of the patients were smoker & most of them had smoked more than 10 cigarettes per day except Non-Q and antero-septal MI patients. Majority (57%) of the patients had systolic blood pressure (SBP) above 140mmHg but had normal diastolic blood pressure (DBP <90mmHg). Serum cholesterol level was high in all patients but majority (55.5%) had LDL within normal range. Less than half (46%) of the patients were diabetic (RBS >8mmol/l).   doi: 10.3329/taj.v18i1.3302 TAJ 2005; 18(1): 37-42


2018 ◽  
Vol 24 (2) ◽  
pp. 95-100
Author(s):  
MB Uddin ◽  
S Yasmin ◽  
M Sanaul Haque ◽  
A Hossain ◽  
KI Jahan

This study was aimed to identify risk factors of preterm LBW babies by following a cross sectional type of comparative study. This study was conducted at inpatient department of paediatrics of Rajshahi Medical College Hospital from January 2009 to December 2010. A total 150 preterm babies were included in this study. The mothers of the babies were studied to identify some selected risk factors. Maternal poor nutritional status (p<.001), low age at conception (p<.003), poor antenatal care (p<.001) and low level of education (p<.002) were found significant socio-economic risk factors. Maternal health related conditions like Antepartum haemorrhage (p<.001), Premature rupture of the membrane (p<.001), toxemia of pregnancy (p<.005), anaemia (p<.002) all were found as the significant contributors of preterm birth. This study might help to reduce the incidence of mortality and morbidity of preterm infants by providing information regarding risk factors.TAJ 2011; 24(2): 95-100


2021 ◽  
Vol 12 (10) ◽  
pp. 39-46
Author(s):  
Subhasish Singh ◽  
Rashmita Pradhan

Background: In order to facilitate diagnosis and timely intervention, it is essential to understand the presentation pattern of cardiac symptoms, and distribution of risk factors in women with Coronary Artery Disease (CAD). However, limited data is available regarding the salient features of CAD in women like distribution of risk factors and anatomical extent. Aims and Objective: The purpose of the present study was to determine the clinical and risk factor profile of women admitted with CAD and to analyze their angiographic findings in relation to the clinical presentation and risk factors in a tertiary care referral center of eastern India. Materials and Methods: In this study we prospectively analysed risk factors and angiographic patterns of 140 consecutive female patients who underwent coronary angiography for suspected CAD over a period of 2 years. Results: CAD most commonly affected females of age group >60yrs with higher incidence among postmenopausal as compared to premenopausal women. Unstable angina was the commonest presentation among patients with normal coronaries as well as obstructive CAD.A substantial percentage of women presenting with anginal pain were angiographically normal. Hypertension was the most common associated risk factor followed by diabetes, elevated total cholesterol, high LDL & low HDL. Most common coronary angiography finding was single vessel disease. On analysis, diabetes mellitus, elevated cholesterol, elevated LDL & triglycerides were most commonly associated with triple vessel disease. Conclusion: The incidence of CAD in females increased with age. Single vessel disease was the commonest presentation with Left Anterior Descending Artery, the most frequently involved vessel.


2017 ◽  
Vol 18 (2) ◽  
pp. 75-79
Author(s):  
Md Mahfuj Ul Anwar ◽  
Shah Md Sarwer Jahan ◽  
Sajeda Afrin ◽  
Md Zakir Hossain

Background and Purpose: Diabetes and ischemic stroke are common diseases that frequently occurring together. Several studies have shown that people with diabetes have approximately twice the risk of ischemic stroke compared with those without diabetes. Although diabetes is a strong risk factor for ischemic stroke, it is still unclear whether risk factors, neuroimaging findings and hospital outcome are different in diabetic and nondiabetic patients. The aim of the present study was to evaluate cerebrovascular risk factor prevalence, neuroimaging findings and hospital outcome in patients between diabetic and non-diabetic of ischaemic stroke.Methods: We conducted a prospective study of 380 consecutive patients with cerebral infarction admitted into Rangpur Medical College Hospital over a 18-month period. With the use of a simple identical data sheet, we recorded the demographics, cardiovascular risk factors, neuroimaging findings and outcome in ischemic stroke patients with and without diabetes.Results: Overall, diabetes was present in 76 patients (20%). Diabetic patients, compared with those without diabetes, were younger (p=.034) and they were more likely to have hypertension (69.7%), hyperlipidemia (28.9%), ischemic heart disease (22.4%), previous cerebral infract (23.7%) and renal impairment (19.7%). Diabetic infract more frequently occurred in thalamus (11.8%), pons (9.2%) and with cerebral posterior involvement (13.2%). Mortality was higher in diabetic group (P = .046).Conclusions: Diabetic patients had higher risk burden for ischemic stroke with poorer short term hospital outcome than non-diabetic subjects. So control of diabetes and other risk factors along with a strict observation of adult individuals’ healthy life-style should warrant successful ischemic stroke prevention in our country.J MEDICINE July 2017; 18 (2) : 75-79


Mediscope ◽  
2018 ◽  
Vol 6 (1) ◽  
pp. 7-11
Author(s):  
MMA Shamim ◽  
ME Haque ◽  
I Chowdhury ◽  
A Debnath ◽  
S Arefin ◽  
...  

Ischemic heart disease is a common cardiac disorder and significant cause of mortality and morbidity worldwide. Effective risk stratification is integral to the management of patients with acute coronary syndromes and associated chronic kidney disease may adversely affect acute ST elevation myocardial infarction (STEMI) outcome. This prospective study was conducted in the Department of Cardiology, Chittagong Medical College Hospital after approval of the protocol for the study with duration of one year. For these purpose 100 patients of STEMI diagnosed by clinical, biochemical and ECG criteria were included in the study. After getting serum creatinine level, estimated glomerular filtration rate was calculated and if it is <60 ml/min then the patient was selected for the study. Among the 100 patients inferior MI was 34%, anterior MI was 20%, extensive anterior MI was 12%, antero-septal MI was 18%, infero-lateral MI was 10%, lateral MI was 2%, high lateral MI was 3% and antero-inferior was 1%. Of these patients heart failure was found in 21% of the patients. The association between incidence of heart failure patients and eGFR was statistically significant (p < 0.05). From this study, it was concluded that impaired renal function among MI patients plays a role for an adverse outcome. Early detection of renal impairment is necessary to avoid increased morbidity and mortality. Mediscope Vol. 6, No. 1: Jan 2019, Page 7-11


2013 ◽  
Vol 20 (Number 1) ◽  
pp. 22-25
Author(s):  
A H M Kamal ◽  
K Hossain ◽  
K E Khuda

Stroke is one of the commonest causes of death and disability in the world. Early detection and correction of risk factors, particularly the major and modifiable risk factors is the mainstay of controlling stroke. The present cross sectional hospital based study was carried out on 100 patients in Holy Family Red crescent Medical College Hospital to evaluate the correlation of hypertension with stroke as an important risk factor and the result of the study was compared with similar types of studies carried out at home and abroad. One hundred hospitalized patients of stroke were chosen randomly for the study. Male patients were more than female with ratio of 1.93:1. Majority of stroke patients were elderly 50 years and above (88%). Most of the patients came from middle and higher socioeconomic status. Hypertension was observed as the most common (82%) risk factor for stroke. Among them most of the patients were known hypertensive (90%) but were getting irregular treatment and only 10 percent cases were newly diagnosed. Most of the patients were hypertensive for 1-5 years.


2018 ◽  
Vol 5 (4) ◽  
pp. 1447
Author(s):  
Sundar K. C. ◽  
Devi Meenakshi K. ◽  
Aruna B. Patil

Background: Retinopathy of prematurity (ROP) affects developing retinal vasculature in premature infants. The risk factors for ROP are prematurity, low birth weight, oxygenation, respiratory distress, infection and frequent blood transfusion. Identification of risk factors leading to ROP may help in planning preventive strategies.Methods: A retrospective analysis of records of preterm babies less than 34 weeks of gestation or birth weight less than 1750 grams and between 34 -36 weeks gestation or 1750-2000 grams birth weight associated with risk factors for ROP admitted to NICU of Kilpauk Medical college hospital from August 2015 to July 2016 were evaluated.Results: Out of a total of 166 babies who were screened for ROP, 37 babies were detected to have ROP (22.3 %). Of these 20 (54%) were female and 17 (46%) were male. The mean birth weight of babies with ROP identified in our study was 1480 grams. The mean gestational age of babies with ROP was 32 weeks. By logistic regression analysis for mode of oxygen therapy as a risk factor for ROP it was found that prongs alone showed the strong risk factor towards ROP which was statistically significant. Sepsis, transfusion and shock requiring inotropes individually and statistical significantly contributed to the risk of ROP.Conclusions: ROP was more common in babies <34 weeks. Sepsis, transfusion and shock requiring inotropes significantly contributed to the risk of ROP. Analysis of the mode of oxygen therapy showed that use of prongs significantly increased the risk of ROP.


2016 ◽  
Vol 5 (1) ◽  
pp. 9-13
Author(s):  
Sultan Ahmed ◽  
Md Aminul Islam ◽  
Mohammad Abdul Bari ◽  
Mahmud Javed Hasan ◽  
Md Ashraful Siddique Pathan ◽  
...  

The present descriptive cross-sectional study was conducted in the department of medicine, Community Based Medical College Hospital Bangladesh over a period of one year during March 2013 to February 2014. The study was conducted to describe Haemorrhagic stroke during summer and winter. An attempt was also made to observe in the frequency of common risk factors of stroke by seasons. A total 146 patients of any age irrespective of sex fulfilling the WHO criteria of acute stroke and confirmed by CT Scan were selected from consecutive admission in the Department of Medicine, Community Based Medical College Hospital Bangladesh. Detail history and through clinical examinations were done. Routine and relevant investigations were carried out. The mean age of the patients was 60.9±14.3 years. A male preponderance was observed in the study. In summer 65.8% of patients and in winter 34.2% patients were presented. Ischemic stroke was present in 52.1% patients and 47.9% patients had haemorrhagic stoke. The study found that the frequency of ischemic stroke during summer (65.8%) was significantly greater than that during winter (34.2%). The frequency of haemorrhagic stroke during winter (65.8%) significant greater than that during summer (39.6%). Hypertension was the most important risk factor and other risk factors were smoking. Diabetes mellitus, tobacco chewing, ischamic heart disease, dyslipidaemia, oral contraceptive pill, alcohol consumption atrial fibrillation and past history of stroke. Increasing age was also noted as a risk factor (60.7%>60 years). Most of the risk factors were homogenously distributed between two seasons and between ischemic and haemorrhagic group. Hypertension was significantly higher in haemorrhagic stroke patients compared to ischemic stroke patients. CBMJ 2016 January: Vol. 05 No. 01 P: 09-13


2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
I Leonova ◽  
S Boldueva ◽  
V Feoktistova ◽  
D Evdokimov

Abstract Funding Acknowledgements Type of funding sources: None. The widespread use of coronary angiography (CAG) in patients with acute coronary syndrome led to the understanding that in some patients myocardial infarction (MI) occurs against angiographically unchanged or slightly modified coronary arteries (CA). In such cases, the so-called "type 2 IM" is diagnosed in some patients, however, to determine the true cause of MI, a modern method of investigation such as optical coherence tomography (OCT) is needed to visualize the intima of the CA and detect a minimal atherosclerotic process.  The purpose of the study was to establish the etiology of MI without obstructive coronary artery disease (MINOCA) using OCT. Materials and methods 160 conclusions of the OCT were analyzed. In 9 (6%) cases, the study was conducted in patients who underwent proven MI (mean age 43,1 ± 13,2, 8 males, 1 female) who had no hemodynamically significant CA stenosis according to CAG data. Results in 2 cases (22%) patients had ST-elevation MI, thrombotic occlusion of the CA (in one case, thrombaspiration was performed). In both patients, spontaneous dissection of the intima of the unmodified CA was detected in the OCT. The remaining 7 patients had non-ST-elevation MI, and in 2 cases, a diagnosis of type 2 MI was established: in both patients, the atherosclerotic plaque was visualized, narrowing the lumen of the CA less than 50%, in one case MI developed against a background of the hypertensive crisis, in another - against a background of spasm of CA. In the remaining 5 patients, OCT revealed subintimal atheromatous, with elements of local dissection of the intima. Thus, in 78% of patients atherosclerosis of CA of different severity (from the subintimal deposition of lipids to the development of atherosclerotic plaque, narrowing the clearance of the SC by less than 50%) was diagnosed. In the analysis of risk factors for coronary heart disease (CHD), 57% of patients with atheromatous CA had more than 2 risk factors for CHD: 3 (42%) smoked, 5 (71%) - obesity, 4 (57% ) - had arterial hypertension, 3 (42%) had dyslipidemia, 1 (14%) had type 2 diabetes. In the group of patients with spontaneous intima dissection of the CA, 1 patient (woman) did not have CHD risk factors, the 2-nd suffered from obesity and hypertension. For all patients a lifestyle correction was recommended; statins, antiplatelets were prescribed, patients with spontaneous dissection of CA had the recommendation of examination in the medical-genetic center. Conclusion Based on the results of the study, in most cases, the cause of IMBOC development was an atherosclerotic lesion of the coronary arteries, which is not always visualized with standard coronary angiography. Basically, the patients were young and middle-aged. Most patients had different risk factors for coronary heart disease.


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