scholarly journals Breast Reduction for Fibrocystic Breast Disease: a case report

2018 ◽  
Vol 7 (2) ◽  
pp. 42-44
Author(s):  
Taslima Sultana ◽  
Maruf Alam ◽  
Shakhawat Hossain
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Connective Tissue ◽  
Breast Reduction ◽  
Breast Disease ◽  
Breast Diseases ◽  
Fibrocystic Disease ◽  
Breast Reduction Surgery ◽  
Fibrocystic Breast Disease ◽  
Clinical Correlate

The pathophysiology of fibrocystic breast disease is determined by estrogen predominance that results in hyper proliferation of connective tissue (fibrosis), the risk of breast cancer is increased twofold to fourfold in these patients. The clinical correlate of fibrocystic disease is reflected by breast and axillary pain or tenderness. The disease progresses with advancing premenopausal age and is most pronounced in women during their 40s. We present a case of 23 years old lady who completely get rid of her symptoms from heavy breast with diagnosed fibrocystic changes immediately after breast reduction surgery. Breast reduction can be a treatment option for fibrocystic breast diseases which are not responding to medical treatment. CBMJ 2018 July: Vol. 07 No. 02 P: 42-44

The Lai Test in Specific Immune-Reactivity Studies of Fibrocystic Breast Disease

1982 ◽  
Vol 68 (4) ◽  
pp. 291-294
Author(s):  
Giorgio Cavallini ◽  
Gilberte Berti
Keyword(s):  
Skeletal Muscle ◽  
Gastric Carcinoma ◽  
Breast Disease ◽  
Immune Reactivity ◽  
Leukocyte Adherence ◽  
Inhibition Assay ◽  
Fibrocystic Disease ◽  
Fibrocystic Breast Disease ◽  
Leukocyte Adherence Inhibition ◽  
Adherence Inhibition

Sixteen cases of fibrocystic breast disease at different histopathologic stage were examined with the leukocyte adherence inhibition assay. Skeletal muscle and gastric carcinoma extracts were used as controls. The glass adherence of leukocytes from patients affected by fibrocystic breast disease was more inhibited when extracts from breasts with fibrocystic disease were used rather than control extracts. Nonadherence indexes (NAIs) were high in 8 cases, around 20 in 4 cases, a little above zero in 2 cases and below zero in 2 cases. NAIs were related to the histopathologic stage: the highest NAIs were found in 8 cases of classic fibrocystic disease, the lowest in 1 case of simple breast fibrosis.

scholarly journals TSH receptor antibodies in breast cancer and benign breast disease: a hospital based study

2017 ◽  
Vol 4 (12) ◽  
pp. 3989
Author(s):  
Jawahar Krishnaswamy ◽  
Reshma Sattar
Keyword(s):  
Breast Cancer ◽  
Prognostic Markers ◽  
Breast Disease ◽  
Tsh Receptor ◽  
Breast Diseases ◽  
Breast Tumours ◽  
Receptor Antibody ◽  
Tsh Receptor Antibody ◽  
Receptor Antibodies ◽  
Tsh Receptor Antibodies

Background: Associations between breast cancer, benign breast tumours and thyroid disorders are reported in numerous studies. Relationship between thyroperoxidase antibodies (TPOAb), thyroglobulin antibodies (TgAb), and breast cancer have been previously demonstrated. However, no analysis has been performed concerning an association between thyrotropin (TSH) receptor antibodies (TSHRAb) and breast cancer. The aim of the study was to evaluate the presence of TSH Receptor antibodies in women with breast cancer or benign breast tumours, and to analyze a possible relationship between TSH Receptor antibodies, and these two groups of breast diseases with emphasis to laboratory findings.Methods: Clinical and laboratory details of 87 women hospitalized were prospectively analyzed, using an Post hoc Tukey HSD for normally distributed continuous data, chi-square test for comparison.Results: TSH Receptor antibody levels in breast cancer was statistically significant. We observed TSHRAb more frequently in patients with breast cancer. We found that TSHRAb is the only variable possessing as a prognostic marker for breast cancer.Conclusions: The present study indicates that the serum levels of TSH Receptor Antibody are significant higher in patients with Breast cancer. These results have implications not only for the screening of patients but also for the development of new prognostic markers. Further high-quality prospective studies are needed to explore whether TSH Receptor Antibodies are potential prognostic markers for patients with Breast cancer.

scholarly journals The Importance of Clinical Data for the Diagnosis of Breast Tumours in North Afghanistan

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Gerhard Stauch ◽  
Peter Fritz ◽  
Rauofi Rokai ◽  
Atiq Sediqi ◽  
Haroon Firooz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Preliminary Data ◽  
Elective Surgery ◽  
Cost Effective ◽  
Final Diagnosis ◽  
Breast Disease ◽  
Developed Countries ◽  
Needle Aspiration ◽  
Breast Diseases ◽  
Data Set

Background. This study was performed in knowledge of the increasing gap between breast disease treatment in countries with restricted resources and developed countries with increasingly sophisticated examination methods. Methods. The authors present the analysis of a breast disease register consisting of diagnostic cases from Mazar e Sharif and Herat in 2018 and 2019. The study comprises a total of 567 cases, which were presented to experts via telemedicine for final diagnosis. 62 cases (10.9%) were excluded due to inacceptable data or insufficient image quality. These data provided by daily diagnostic classification were used for the built-up of a profile for each frequent breast disease and a breast cancer register. All images and cases were seen by at least 3 independent experts. The diagnoses were made in 60% of cases by cytology of fine needle aspiration and in 40% by histological images. Results. For each entity of breast diseases (e.g., fibroadenoma), a profile of context variables was constructed allowing to assist medical decisions, as “wait and see,” elective surgery or immediate surgical intervention with R0 (complete) resection. These “profiles” could be described for fibroadenoma, mastitis, galactocele, fibrous-cystic disease, and invasive breast cancer. Conclusions. The presented preliminary data set could serve as a cost-effective basis for a North Afghan breast cancer registry, with option to extent to a national model. These preliminary data are transformed in profiles of breast diseases, which are used by the local physicians in charge of breast disease patients. Each new case can be compared by the local treating physician with the profile of all preceded cases with the same diagnosis.

Benign Breast Diseases and Body Mass Index: Is There a Correlation?

2014 ◽  
Vol 80 (5) ◽  
pp. 461-465 ◽  
Author(s):  
Stacey O'Brien ◽  
Gopal Chandru Kowdley
Keyword(s):  
Breast Cancer ◽  
Body Mass Index ◽  
Body Mass ◽  
Breast Biopsy ◽  
Statistical Significance ◽  
Breast Disease ◽  
Breast Diseases ◽  
Increased Risk ◽  
Relationship Of ◽  
Risk Of Cancer

Breast cancer is the leading cancer affecting women in America. Body mass index (BMI) is a known risk factor for the development of breast cancer. The relationship of BMI to benign breast disease is less clear. In addition, certain benign pathologies are associated with an increased risk of cancer. We sought to measure the incidence of benign pathologies and to correlate these findings with BMI and age. All patients undergoing breast biopsy at our center from 2000 to 2005 were identified (n = 1717). Age, BMI, family history, sex, and diagnosis were determined. Patients were grouped into BMI, age, and intervention groups. χ2 ( P < 0.05) was used to identify statistical significance. Fibrocystic disease and fibroadenoma were seen with a lower incidence for patients older than 55 years of age, whereas pathologies requiring further surgical intervention were seen in higher proportions in patients older than 55 years of age. All pathologies were noted to decrease with increasing BMI, except for fibroadenoma, which peaked in BMI group 25 to 29.9 kg/m2. The presence of benign pathologies was associated with age as expected. Interestingly, although BMI is associated with increased risk of breast cancer, increasing BMI was not associated with benign pathologies that are associated with increased risk of breast cancer. Further study of this area is warranted.

scholarly journals Profiles of Breast Diseases among Women Seeking for Treatment during Covid-19 Pandemic at Surgery OPD of Medical University of Bangladesh

2021 ◽  
Vol 8 (1) ◽  
pp. 3-6
Author(s):  
Bidyut Chandra Debnath ◽  
Abanti Ghosh ◽  
Abul Kalam Chowdhury ◽  
Rana Jahangir ◽  
Ferdous Alam ◽  
...  
Keyword(s):  
Breast Disease ◽  
Cross Sectional Study ◽  
Breast Diseases ◽  
Age Group ◽  
Fibrocystic Disease ◽  
Breast Lump ◽  
Cross Sectional ◽  
Study Population ◽  
The Mean ◽  
Medical University

Background: Different pathology of breast is found among the women. Objective: The purpose of the present study was to see the profiles of breast disease among women seeking for treatment during Covid-19 pandemic at the OPD of medical university of Bangladesh. Methodology: This descriptive cross-sectional study was conducted in the Department of Surgery at Bangabandhu Shiekh Mujib Medical University, Dhaka, Bangladesh from 1 April to 31 October 2020 for a period of six months. All the women who were attended at the OPD of the Department of Surgery with the different complaints of breast at any age were selected as study population. The different disease profiles were recorded in the data sheet. Result: A total number of 1625 women were recruited for this study. The mean age with standard deviation of the study population was 36.4±12.54 years. Among 1492 women the most common breast complaints was mastalgia which was 492(29.9%) cases followed by fibrocystic disease, breast lump, fibroadenoma and carcinoma breast which was 296(18.0%) cases, 202(12.3%) cases, 141(8.6%) cases and 84(5.1%) cases respectively. Similarly duct ectasia, fibroadenoma, fibrocystic disease and lipoma were also most common among the less than or equal to 45 years age group of women which were 47(94.0%) cases, 137(97.2%) cases, 269(90.9%) cases and 75(51.4%) cases respectively. Conclusion: In conclusion breast lump and fibrocystic disease are the most common diseases among the women attending during covid19 era. Journal of Current and Advance Medical Research, January 2021;8(1):3-6

scholarly journals Vitex agnus-castus Ze 440 extract in the therapy of cyclic mastodynia in women with non-tumor breast damage

2021 ◽  
pp. 79-82
Author(s):  
O.O. Kovaliov ◽  
L.I. Alivapova
Keyword(s):  
Breast Lesion ◽  
Hormonal Treatment ◽  
Pain Syndrome ◽  
Breast Disease ◽  
Breast Diseases ◽  
Fibrocystic Breast Disease ◽  
Progesterone Synthesis ◽  
Main Effect ◽  
Agnus Castus ◽  
Severe Degree

Cyclic mastalgia of varying intensity occurs every month in at least 70% of women, persistent pain in the mammary glands of moderate and severe degree is occur in about 50% of patients with benign mastopathy. The cause of mastodynia is the morphofunctional rearrangement of the glandular and stromal components of tissues with the expansion of ducts and proliferation of epithelial structures due to a lack of progesterone and an increase in prolactin levels. Therapy for cyclical and chronic mastalgia is empirical and not always effective. Herbal medicine with Vitex agnus-castus is a reasonable alternative to hormonal treatment for women suffering from cyclic mastalgia in combination with other manifestations of premenstrual syndrome. The main effect of such drugs is an increase of luteinizing hormone and progesterone synthesis, effect on the hypothalamic-pituitary system, prolactin and endorphins release, which can increase the level of endogenous opioids.Purpose of the study: to study the effect of the phytopreparation Prefemin (Vitex agnus-castus extract Ze 440) on the intensity of chronic pain syndrome in women with diffuse non-tumor breast lesion. Materials and methods. The study involved 30 women aged 22 to 43 years with various types of benign breast diseases and chest pain lasting at least 3 months. In 12 patients there was diffuse fibroadenoma, in 18 – diffuse cystofibroadenoma (small cystic variant) and duct ectasia.Results. Therapy with Prefemin (Ze 440) allowed to completely eliminate pain syndrome in 93.3% of women and to reduce the frequency of mastodynia in the group with moderate severity in 90.0% of patients with diffuse fibroadenoma and cystofibroadenoma.Conclusions. Phytopreparation Prefemin, which is obtained from the medicinal plant Vitex agnus-castus, has demonstrated high efficacy in the mastalgia treatment in women with diffuse fibrocystic breast disease. This drug was well tolerated and there were no side effects.

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