scholarly journals Correlation of pap smear and colposcopic finding of cervix with histopatholgiocal report in a group of patient attending in a tertiary hospital

2013 ◽  
Vol 22 (1) ◽  
pp. 39-44
Author(s):  
Suraiya Parvin ◽  
Nazneen Kabir ◽  
Yeasmin Samad Lipe ◽  
Khaleda Nasreen ◽  
KM Nurul Alam
Keyword(s):  
Pap Smear ◽  
Diagnostic Value ◽  
Tertiary Hospital ◽  
Cervical Cytology ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
Abnormal Cervical Cytology ◽  
One Year ◽  
Colposcopy Clinic

Objective: To correlate Pap’s smear and colposcopic finding of cervix with histopathological report of abnormal area of cervix in a group of patient attending a tertiary hospital. Methods: It was a cross-sectional prospective study done in one year period from January to December 2007 in Colposcopy Clinic of Institute of Child and Maternal Health (ICMH) Hospital, Dhaka. The study carried out including fifty two female patients having clinically unhealthy cervices as in the form of hypertrophy, erosion, congestion or bleeds on touch or having positive pap smear found during P/V or P/S examination, attending gynaecology out patient department of ICMH Hospital after fulfilling all the inclusion criteria. Result: The present study showed a correlation between cervical cytology and colposcopically directed biopsy, the correlation was accurate within one grade in 39 of 51 cases (76.16%) (as cytology was not done in one case). Other studies showed cytologic accuracy (within one level of histologic finding) to about 83% and 88% cases. Conclusion: The study done here shows excellent correlation between findings of colposcopy with that of histopathology of guided biopsy. It also confirms the diagnostic value of colposcopy in the management of women with abnormal cervical cytology with squamous atypia. DOI: http://dx.doi.org/10.3329/jdmc.v22i1.15604 J Dhaka Medical College, Vol. 22, No. 1, April, 2013, Page 39-44

The prevalence of abnormal cervical cytology among postnatal clinic attendees at the University of Calabar Teaching Hospital, Calabar, Nigeria.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e12568-e12568
Author(s):  
Boniface Uji Ago
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Gynecologic Oncology ◽  
Cross Sectional Study ◽  
Cervical Cytology ◽  
Screening Methods ◽  
Low Grade ◽  
Cross Sectional ◽  
Preventable Disease ◽  
Abnormal Cervical Cytology

e12568 Background: Carcinoma of the uterine cervix is a deadly but preventable disease. It is still a major gynecologic problem in our subregion. Cervical cytology remains the key to its early detection and prompt treatment. Methods: This was a prospective cross sectional study of postnatal women to determine the prevalence of abnormal cervical cytology and their socio-demographic characteristics. Institutional ethical clearance and informed consent of participants were obtained. Aye's spatula and endocervical brush were used to collect specimen from the ectocervix and endocervix respectively and smeared on individually labelled glass slides. The samples were treated using the conventional Papanicolaou staining method and reported using the Bethesda system. Researcher-administered questionnaire generated data as well as results of cytology were analyzed using Epi-Info version 3.5.1.0 (CDC Atlanta USA 2008). Results: There were 100 women screened. Three percent had low grade squamous intraepithelial lesion. Colposcopy done, however, did not reveal abnormal findings. Ninety-five percent of the women had no prior knowledge of cervical cancer and Pap smear. Two percent of the women had a family history of cervical cancer and both patients died of the disease due to lack of facilities for treatment. Conclusions: Cervical cancer is a preventable disease. Women in our subregion are under-screened. Effective screening methods are the mainstay in its prevention. Availability of well equipped gynecologic oncology centers with personnel training are a necessary end to this carnage.

scholarly journals A correlation study of cervical cytology on Pap smear with cervical biopsy in a tertiary hospital of Eastern Nepal

2018 ◽  
Vol 8 (2) ◽  
pp. 1389-1392
Author(s):  
Nirajan Mainali ◽  
Neha Homagai ◽  
Niraj Nepal ◽  
Prabesh Choudhary
Keyword(s):  
Pap Smear ◽  
Early Stage ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Correlation Study ◽  
Pap Smears ◽  
Carcinoma Cervix ◽  
Cross Sectional ◽  
Medical College ◽  
Cervical Biopsy

Background: Carcinoma cervix is among a curable cancer, if identified at an early stage. Pap smear is a simple, safe, noninvasive, outdoor and effective method for detection of lesions of the cervix but it fails to localize the lesion. Cervical biopsy, on the other hand is a gold standard but invasive technique.Materials and Methods: A prospective cross-sectional study was done in Nobel medical college from January 16, 2017 to January 15, 2018 where all pap smears received in a Department of Pathology were included in the study. However, only cases that had undergone both Pap smear and cervical biopsy were compared. Out of the 1492 pap smears, 118 cases underwent biopsy. Correlation was then done regarding cytological and histological diagnosis.Results: Majority of the cytological findings were normal. 7 patients of HSIL revealed moderate dysplasia and higher lesions in biopsy. 2 cases were that of adenocarcinoma which were diagnosed as inflammatory smear in Pap smear.Conclusion: Cervical Pap smear is reliable screening test to identify high grade squamous cell lesions and carcinoma, but it fails to localize the lesion and adenocarcinoma is hard to identify in a pap smear. Hence, cervical biopsy should be carried out to confirm the findings of Pap smear and in case of strong clinical suspicion.

scholarly journals Significance of Reporting Cannon Balls in Diagnosing Bacterial Vaginosis Infection in PAP Smear

2021 ◽  
Vol 23 (2) ◽  
pp. 109-113
Author(s):  
Kricha Pande ◽  
Shraddha Koirala ◽  
Astha Shrestha
Keyword(s):  
Bacterial Vaginosis ◽  
Pap Smear ◽  
College Teaching ◽  
Cross Sectional Study ◽  
Gardnerella Vaginalis ◽  
Pap Smears ◽  
Cross Sectional ◽  
Medical College ◽  
The Mean ◽  
One Year

Bacterial vaginosis is the most common cause of vaginitis. It is caused by depopulation of lactobacilli from the normal vaginal flora and overgrowth of Gardnerella vaginalis and other anaerobic species. Pap smear being a screening and diagnostic tool for malignancy, is equally important to diagnose infective pathology as well. This study tried to establish the significance of reporting the presence of cannon balls in Pap smears and whether their presence suggested bacterial vaginosis or not. This was a cross sectional study conducted at Nepal Medical College, Teaching Hospital (NMCTH), Kathmandu for duration of one year (January 2020 to December 2020). Pap smears were sent from gynaecology department and standard routine Pap stain was done in Pathology Department. Presence of bacterial vaginosis and cannon balls were noted. Total of 799 Pap smears were received. The mean age of bacterial vaginosis was 38.2 ± 9.6 years. The age group of 31-40 years (n=32, 39%) was most commonly affected. Bacterial vaginosis was seen in 81 pap smears out of 799 pap smears. The prevalence of bacterial vaginosis was 10.1%. Of the total of 799 cases of Pap smears, cannon balls were seen in 9.1% cases and among the bacterial vaginosis, cannon balls were seen in 48% cases. There was significant association between cannonballs and bacterial vaginosis (p < 0.0001). Thus, the present study re-enforces the fact that Pap smear is also very effective tool to diagnose bacterial vaginosis.

Comparison of Visual Inspection with Acetic Acid and the Pap Smear for Cervical Cancer Screening

2017 ◽  
Vol 62 (1) ◽  
pp. 34-38 ◽  
Author(s):  
Parul Sinha ◽  
Pritika Srivastava ◽  
Anand Srivastava
Keyword(s):  
Cervical Cancer ◽  
Acetic Acid ◽  
Visual Inspection ◽  
Pap Smear ◽  
Cross Sectional Study ◽  
Test Accuracy ◽  
Sectional Study ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Medical College

Objective: To evaluate the efficacy of visual inspection with acetic acid (VIA) in the early detection of cervical cancer and compare it with the Pap smear. Study Design: This was a cross-sectional study conducted over a period of 3 months. A total of 316 patients who attended the Gynecology Outpatient Department of Era's Lucknow Medical College and Hospital, fulfilled the inclusion criteria, and gave their informed consent were included. Results: VIA was found positive in 38 patients (12.6%). Pap smear was positive in 31 patients (10.3%). Twenty-eight patients had a positive VIA and a positive Pap smear, 3 had a negative VIA and a positive Pap smear, 10 had a positive VIA and a negative Pap smear, and 34 had a negative VIA and a negative Pap smear. Conclusion: The sensitivity of VIA and the Pap smear was found to be nearly equal, 93.3 and 93.8%, respectively. The Pap smear was found to be more specific than VIA, i.e., 72.9 versus 60%. In terms of test accuracy, the Pap smear was found to have greater test accuracy, i.e., 77.3 versus 66.7% for VIA.

scholarly journals Prevalence of Adenomyosis in Hysterectomy Specimens Performed at a Tertiary Hospital of Kathmandu, Nepal

2020 ◽  
Vol 22 (3) ◽  
pp. 118-122
Author(s):  
Kricha Pande ◽  
S Koirala ◽  
A Giri
Keyword(s):  
Incidental Finding ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Age Group ◽  
Cross Sectional ◽  
Medical College ◽  
Intraepithelial Lesion ◽  
The Mean ◽  
One Year ◽  
Serous Cyst Adenoma

Adenomyosis is a common condition, detected in 15-30% of hysterectomy specimens. It is characterized by the presence of endometrial glands and stroma within the myometrium. The data regarding incidence or incidental finding of adenomyosis in hysterectomy specimen is lacking despite this condition being common and bearing serious implications in symptomatology as well as in infertility. Adenomyosis can be incidental finding in hysterectomy done for other gynecologic pathology as well. Hence, this present study has established the prevalence of adenomyosis as well as it’s association with other uterine pathology in routine hysterectomy specimens. This was a cross sectional study conducted at Nepal Medical College and Teaching Hospital (NMCTH), Kathmandu for a duration of one year (March 2019 to February 2020). Total of 154 hysterectomies were included in the study, out of which 37 cases showed adenomyosis. The prevalence of adenomyosis was 24%. The age group for adenomyosis ranged from 36 years to 52 years with the mean age of 44 ± 4.4 years. The most common pathology other than adenomyosis was leiomyoma (19 cases) followed by two cases of endometriotic cyst, two cases of endometrial polyp, one case of high grade squamous intraepithelial lesion (HSIL), one case of hyperplasia of endometrium with atypia, and one case of serous cyst adenoma of ovary. Thus this study showed that the prevalence of adenomyosis was 24% and was seen higher in the age group of 35-50 years. The most frequent co-pathology in these adenomyosis cases was leiomyoma.

scholarly journals Frequency of abnormal cervical cytology in symptomatic women.

2021 ◽  
Vol 28 (08) ◽  
pp. 1156-1160
Author(s):  
Hafiza Khatoon ◽  
◽  
Nousheen Mushtaq ◽  
Safia - ◽  
Fiza Ali Khan ◽  
...  
Keyword(s):  
Pap Smear ◽  
Cross Sectional Study ◽  
Cervical Cytology ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Abnormal Cervical Cytology ◽  
Large Numbers ◽  
Cervical Diseases ◽  
Study Setting ◽  
Smear Testing

Objective: To estimate the frequency of abnormal cervical cytology detected by Pap smear. Study Design: Cross Sectional Study. Setting: Department of Obstetrics and Gynaecology Gambat Institute of Medical Sciences Gambat, Khairpur Sindh. Period: November 2018 to June 2019. Material & Methods: A total of 160 women with the complaint of heavy vaginal discharge and moderate to servere lowere abdominal pain more than 6 weeks were included in this study. Per speculum examination of cervix was carried out with the help of cuscos speculum before PAP smear and finding were noted, After labeling the sample was sent to histopathology for cytological examination. Results: The average age of the patient’s was 37.68±7.46 years. Percentage of normal smears 10%, advance disease 1.3% and percentage of inflammatory smear is 63.8% while frequency of abnormal cervical cytology was observed in 25% in which CIN-1 was 12.5%, CIN-2 was 11.3% and CIN-3 was 1.3%. Conclusion: Our population have large numbers of undiagnosed cervical diseases. Therefore, Pap smear testing should be widely used throughout Pakistan to reduce the incidence of cervical cancer.

Comparison of Heffner Criteria and Light Criteria in Differentiating Exudative and Transudative Pleural Effusion

2020 ◽  
Vol 22 (3) ◽  
pp. 141-145
Author(s):  
Krishna Chandra Devkota ◽  
S Hamal ◽  
PP Panta
Keyword(s):  
Pleural Effusion ◽  
Cross Sectional Study ◽  
Pleural Space ◽  
Sectional Study ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
The Common ◽  
The Mean ◽  
Exudative Pleural Effusion

Pleural effusion is present when there is >15ml of fluid is accumulated in the pleural space. It can be divided into two types; exudative and transudative pleural effusion. Tuberculosis and parapneumonic effusion are the common cause of exudative pleural effusion whereas heart failure accounts for most of the cases of transudative pleural effusion. This study was a hospital based cross sectional study performed at Nepal Medical College during the period of January 2016-December 2016. A total of 50 patients who fulfilled the inclusion criteria were enrolled. Pleural effusion was confirmed by clinical examination and radiology. After confirmation of pleural effusion, pleural fluid was aspirated and was analysed for protein, LDH, cholesterol. The Heffner criteria was compared with Light criteria to classify exudative or transudative pleural effusion. Among 50 patients, 30 were male and 20 were female. The mean age of patient was 45.4±21.85 years. The sensitivity and specificity of using Light criteria to detect the two type of pleural effusion was 100% and 90.9%, whereas using Heffner criteria was 94.87%, 100% respectively(P<0.01). There are variety of causes for development of pleural effusion and no one criteria is definite to differentiate between exudative or transudative effusion. In this study Light criteria was more sensitive whereas Heffner criteria was more specific to classify exudative pleural effusion. Hence a combination of criteria might be useful in case where there is difficulty to identify the cause of pleural effusion.

Determine the Frequency of Sensorineural Deafness in Children with Cerebral Palsy

2021 ◽  
Vol 15 (6) ◽  
pp. 1478-1481
Author(s):  
A. G. Magsi ◽  
M. U. Rehman ◽  
F. A. Soomro ◽  
Z. Ahmed ◽  
A. Q. Memon
Keyword(s):  
Hearing Loss ◽  
Cerebral Palsy ◽  
Sensorineural Deafness ◽  
Inclusion Criteria ◽  
Profound Hearing Loss ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Hearing Assessment ◽  
Normal Head

Aim: To determine the frequency of sensorineural deafness in child with cerebral palsy. Study Design: Descriptive/cross-sectional Place and Duration of Study: Department of Neurology, Chandka Medical College Hospital, Larkana from 1st October 2020 to 31st March 2021. Methodology: One hundred and seventy patients of both genders age between 1-14 years were enrolled. Children diagnosed as having cerebral palsy and fulfilling the inclusion criteria was included. Hearing assessment was done with audiometry and degree of hearing loss was recorded in both ears in the form of mild, moderate, severe and profound degree of hearing loss. Results: Most of the patients 90 (52.94%) were between 1-5 years old followed by 51(30%) patients between 5-10 years with mean age of 4.8±7.8 years. 115 (67.65%) cases were males and 55 (32.35%) females. 54 (31.8%) cases had microcephaly and116 (68.2) cases had normal head circumference. Among 170 cases of cerebral palsy 48 (28.23%) cases had hearing loss and 122 (71.77%) of patients of CP had no hearing deficit. Among 48 cases of CP with hearing loss 15 (31.25%) cases had mild, 14 (29.17) cases had moderate, 10 (20.83%) had severe and 11 (22.92%) cases had profound hearing loss. Conclusion: The frequency of sensorineural deficit is high and significantly associated with cerebral palsy patients. Keywords: Degree of hearing loss, Sensorineural hearing loss, Cerebral palsy

scholarly journals A Cross Sectional Descriptive Study of Etiology and Clinical Pattern of Liver Abscess : 50 Cases

2013 ◽  
Vol 12 (3) ◽  
pp. 44-48
Author(s):  
Joyabrata Das ◽  
Subash Majumdar ◽  
Subrata Das ◽  
Saiem Nurul Anwar ◽  
Hossain Ahmed ◽  
...  
Keyword(s):  
Clinical Features ◽  
Liver Abscess ◽  
Rural Areas ◽  
Descriptive Study ◽  
Age Group ◽  
Cross Sectional ◽  
Medical College ◽  
Abdominal Abscesses ◽  
One Year ◽  
The Right

Background: The liver is the organ most subjected to the development of abscesses and made up 48 % of all visceral abscesses' and 7% of all intra abdominal abscesses. Liver abscess should be suspected when there is a combination of fever, leucocytosis, constitutional symptoms, and pain in the right upper quadrant, and tenderness over the liver or right lower rib cage. The liver is affected by a number of local and disseminated infections; their frequency and types vary considerably around the world. Parasitic disorders are more prevalent in developing countries. Methods: It was a cross-sectional descriptive study. The cases were taken from the admitted patients of Medicine unit of SMCH, Chittagong. The study was conducted over a period of one year with a sample size of 50 patients and sample was taken by purposive sampling. Results: Among 50 patients 40 (80%) were diagnosed as ALA and 10 (20%) were diagnosed as PLA. ALA cases are common in 21-30 years age group & PLA cases are more common in >50 years of age group. Majority of the cases were from rural area. Common clinical features were fever, abdominal pain, nausea and tender hepatomegaly. Diarrhea was present on admission in 7 (15.9%) patients of ALA. Anaemia was common in both but polymorphonuclear leucocytosis was moderate to severe in PLA. Microscopic examination of stool samples for E. Histolytica trophozoites was positive in 3 (7.5%) cases and cysts in 4(10%) cases. Nine patients had right sided pleural effusion. Conclusions: Clinical features are common in both ALA and PLA. Liver abscesses are more common in men and more prevalent in rural areas. ALA more commonly occurs in 21-30 years age group but can occur at any age. Pyogenic abscess is more common in older age group (>50 years) and E. Coli is the commonest organism. Chattagram Maa-O-Shishu Hospital Medical College Journal Volume 12, Issue 3, September 2013: 44-48

scholarly journals Prevalence of abnormal cervical cytology and HPV DNA positivity among HIV positive women

2019 ◽  
Vol 8 (9) ◽  
pp. 3649
Author(s):  
Sunita Malik ◽  
Supriti Kumari ◽  
Harsha S. Gaikwad ◽  
Archana Mishra ◽  
Mausumi Bharadwaj
Keyword(s):  
Hpv Infection ◽  
Cervical Cytology ◽  
Hiv Positive ◽  
Abnormal Cytology ◽  
Cross Sectional ◽  
Hpv Dna ◽  
Hpv Dna Testing ◽  
Abnormal Cervical Cytology ◽  
Hiv Positive Women ◽  
Relationship Of

Background: The relationship among HIV, HPV, and development of CIN is complex and incompletely understood. Present study is undertaken to find out the prevalence and relationship of abnormal cervical cytology and HPV infection in HIV positive women.Methods: This was a cross-sectional, case control study conducted on 95 HIV seropositive and 95 seronegative women. Specimen was collected from the cervix for HPV DNA testing, subtyping and cytology.Results: HPV DNA positivity was higher in seropositive group (18.6% vs. 7.4%). Premalignant conditions were found only in seropositive group. At CD4 count <249 HPV DNA positivity was 53%, at 250-499 the percentage of HPV DNA positivity was 31% and at >500 HPV DNA positivity was 19%.Conclusions: Prevalence of abnormal cytology and HPV DNA positivity is higher amongst HIV positive women and there is an association between HPV DNA positivity with lower CD4 counts. 

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