scholarly journals Explained infertility among the couple attending the infertility unit of Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh

2015 ◽  
Vol 23 (1) ◽  
pp. 114-120
Author(s):  
Arifa Sultana ◽  
Shaorin Tanira ◽  
Sanchita Adhikary ◽  
Kashfia Ahmed Keya ◽  
Sayeba Akhter
Keyword(s):  
Semen Analysis ◽  
Ovarian Dysfunction ◽  
Male Factor ◽  
Cross Sectional ◽  
Polycystic Ovarian Disease ◽  
Ovarian Disease ◽  
Tubal Occlusion ◽  
Fibroid Uterus ◽  
Common Causes ◽  
Medical University

Context: The causes of infertility vary from country to country among different cultural, environmental and socio economic groups. The aim of the study was to explain the causes of infertility among the couple attending infertility unit of Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh and to compare with previous studies of both local and abroad. Methods: This cross sectional study was carried out between September 2007 and March 2008 at infertility unit of BSMMU Hospital, Dhaka, among 110 couples, who had tried unsuccessfully for more than one year to reproduce. The data included history, physical examination and relevant investigations for female partners and male partners. Results: The age group of 25-30 years was the most vulnerable as they represented 52% of primary and 51.42% of secondary infertility. Among the 110 subfertile couples, 43.63% had female factor problems; 20% were suffering from male factor problems. In 21.81% of cases both male and female were responsible. In 14.54% cases, there were no causes, and, therefore, remain unexplained infertility. Among women, primary subfertility was 68.18%, secondary subfertility was 31.81% and among men, it was 79% and 21% respectively. Most of the infertile couples (43.64%) were trying for 2-5 years. In this study, most common cause was ovarian dysfunction (33.63%). Among them, anovulation with regular menstruation was found in 60%, polycystic ovarian disease in 32%, hyperprolactinaemia in 16% cases. Bilateral tubal occlusion was found in 8% and pelvic adhesions in 24% by doing laparoscopy. In addition, 10% of patients had endometriosis. Fibroid uterus was found in 26% cases. Among the primary subfertility cases, common causes were anovulation with regular menstruation (14.66%) and polycystic ovarian disease (12%). 40% of secondary subfertility was related with menstrual regulation (MR). Among male factors, azoospermia was found in 6.36% cases, oligozoospermia in 10.9% cases, asthenozoospermia 18.18%, teratozoospermia was in 6.36% cases. Conclusion: Primary subfertility cases were more common than secondary subfertility cases. Ovarian dysfunction was the common causes of subfertility. Other factors were abnormal semen analysis, endometriosis, tubal occlusion, pelvic adhesions and fibroid uterus. DOI: http://dx.doi.org/10.3329/jdmc.v23i1.22705 J Dhaka Medical College, Vol. 23, No.1, April, 2014, Page 114-120

scholarly journals Etiologic Factors of Infertility in a Referral Hospital (BSMMU, Bangladesh)

2014 ◽  
Vol 14 (2) ◽  
pp. 110-113
Author(s):  
Begum Rokeya Anwar ◽  
Parveen Fatima ◽  
Nasim Afza ◽  
Tazkia Tarannum ◽  
Nazneen Begum ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Male Factor ◽  
Cross Sectional ◽  
Male And Female ◽  
Study Results ◽  
Common Causes ◽  
Tubal Blockage ◽  
Tubal Factor ◽  
One Year ◽  
Medical University

Background: Infertility is defined as the failure in pregnancy after one year of unprotected intercourse. Several centers have reported different causes of infertility. The most common causes of infertility include: Female factors such as ovulation dysfunction and tubal factor; male factors like sperm disturbance as well as ; both male and female factors and unexplained infertility. The aim of this study was to find out the etiologic factors of infertility in BSMMU (Bangabandhu Sheik Mujib Medical University, Dhaka, Bangladesh)Methods: This cross sectional study was done at the Out Patient Department (OPD) of infertility in BSMMU during the period of December 2004 to March 2005. One hundred infertile couples with necessary investigations were reviewed for the study. Results: In this study the frequency of primary and secondary infertility was 56% and 44% respectively. Among 100 couples 57% had female factor, 25% had both male and female factors and in 3% had male factor and in 15% of couple, the causes of infertility were unknown. Among women, different infertility factors included: Tubal factor 33%, Ovarian factor 12% and endometriosis 11%. In this study tubal blockage were detected in 50% cases of female secondary subfertility following Menstruation Regulation (M/R). Result showed 82% of men had normal spermogram 28%, had sperm disturbance including Oligospermia, Asthenospermia, Oligoasthenospermia and teratospermia. Conclusion: Although female factor was the most common cause of infertility in BSMMU, we can not conclude that this factor is the most common causes of infertility in Bangladesh. Since this centre is considered as referral centre especially for female infertility. We suggest performance of similar researches with big sample size in different institution to evaluate most common causes of infertility in Bangladesh.DOI: http://dx.doi.org/10.3329/jom.v14i2.18460 J Medicine 2013, 14(2): 110-113

scholarly journals Study on Transvaginal Sonographic Diagnosis of Infertility of Infertility: A Comparative Outcome With Clinical Correlations

2012 ◽  
Vol 18 (Number 1) ◽  
pp. 9-19
Author(s):  
T Begum ◽  
F Begum ◽  
Md. N Islam
Keyword(s):  
Semen Analysis ◽  
Cyst Formation ◽  
Normal Range ◽  
Male Factor ◽  
Cross Sectional ◽  
Obstetrics And Gynaecology ◽  
Clinical Correlations ◽  
Medical University ◽  
Renal Abnormalities

A cross sectional comparative study was doneon ran.cvaginal sonographic (TVS) findings to diagnose infertility in 110 patients attended theta t.patient department of Obstetrics and Gynaecology at Bangabandhu Sheikh Mt jib Medical University (BSMM1.1). The study was done with an object ro asses the role of traavvaginal ultra sonography as a sensitive detector for the diagnosis of poly cystic ovarian disease. endonteriomas. leontyomas.retroversion of itterus.pelvic inflammatory disease. adnegal mass or pelvic tumour. congenital abnormalities of paramesonephric (niillarion)ducts and also its association with renal abnormalities. The age of the study patients ranged from 19-40 yrs. They were grouped into three categories. Amongst them 58 cases was represented with primary infertility which is 47.27 % Mike total cases. In this study 37 patients was diagnosed by TVS as having PCOD amongst them II patients presented with oligomenorrhoea. Comparison between clinical correlation and TVS findings were done in which 15 patients clinically seemed to have with endometrioma with cyst formation which correlates 10 cases of TVS findings. TVS findings were normal in 21 patients. But they had come only with primary or secondary infertility. This study included only those patients Otiose husband's semen analysis is within normal range and no other male factor. These are the unexplained infertility.

Genetic factors in common disorders of female infertility

2000 ◽  
Vol 8 (3) ◽  
pp. 173-202 ◽  
Author(s):  
JL Simpson
Keyword(s):  
Premature Ovarian Failure ◽  
Genetic Factors ◽  
Ovarian Failure ◽  
Female Infertility ◽  
Gonadal Differentiation ◽  
Polycystic Ovarian Disease ◽  
Ovarian Disease ◽  
Current Contribution ◽  
Common Causes ◽  
Gonadal Failure

Female infertility results from a myriad of causes – genetic and nongenetic. Sometimes a genetic aetiology is clearly evident. In other disorders heritable tendencies exist, but the precise genetic aetiology remains obscure. In this communication we shall consider the genetics of selected common causes of female infertility: premature ovarian failure; leiomyomata; polycystic ovarian disease; endometriosis. Not discussed here are disorders of gonadal differentiation primarily causing gonadal failure and disorders of female internal ducts, both considered elsewhere by the author and colleagues. The current contribution inevitably mirrors these other publications.

scholarly journals ASSOCIATION OF VARICOCELE WITH OLIGOSPERMIA AND AZOSPERMIA

1969 ◽  
Vol 3 (2) ◽  
pp. 303-307
Author(s):  
NAIK ZADA ◽  
SHAFI ULLAH KHAN ◽  
RIAZ AHMAD KHAN
Keyword(s):  
Sperm Count ◽  
Human Subjects ◽  
Semen Analysis ◽  
Cross Sectional Study ◽  
Semen Parameters ◽  
Male Factor ◽  
Cross Sectional ◽  
Seminal Parameters ◽  
The Mean ◽  
Age Range

OBJECTIVE: To determine the frequency of abnormal semen parameters among patients presenting withvaricocele1METHODS:It was a descriptive cross-sectional study conducted at the Department of Urology Institute ofkidney diseases Hayat Abad Medical Complex Peshawar and Cenna hospital Saidu Sharif Swat. The studywas carried out on 139 human subjects with clinical evidence of varicocele between age range of 15-45years.The diagnosis of varicocele was based on palpable and/or visible scrotal lump of testicular veins(pampiniform plexus) and was diagnosed on the basis of clinical examination. Semen analysis was carriedout in all these patients and information wascollected on pre designed proforma.RESULTS:The study included a total of 139 patients with varicocele. The mean age of patient was 30 years(15-45) among the patients having symptoms of varicocele. The Mean ±SD for duration of varicocelesymptoms was 9.32 ± 9.70 months. 6.5% (n=9) patients were having azoospermia and 20.1% (n=28)patients had oligozoospermia.CONCLUSION: Patients with varicocele have poor seminal parameters in terms of sperm count i.e.oligozoospermia and azoospermia responsible for male factor infertility in majority ofcases.KEYWORDS:varicocele;seminal parameters;sperm count, infertility

scholarly journals Prevalence and Patterns of Male Infertility Based on Semen Analysis in Patients Visiting Massawa Hospital; Eritrea: Cross-Sectional Study; 2020

2021 ◽  
Author(s):  
Berhe Tesfai ◽  
Fitsum Kibreab ◽  
Hailemichael Gebremariam ◽  
Liwam Abraham
Keyword(s):  
Male Infertility ◽  
Sperm Motility ◽  
Sperm Count ◽  
Semen Analysis ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Cross Sectional ◽  
Semen Volume ◽  
Primary Type ◽  
Study Participants

Abstract Background Semen analysis is the first step to identify male factor infertility. World Health Organization estimates that male factor accounts for 50% of couple sub-fertility. The objective of this study was to determine the prevalence and patterns of male factor infertility based on semen analysis in patients visiting Massawa Hospital with infertility complaints. Methods It was a retrospective, descriptive cross sectional hospital based type of study with a census sampling method. Patient’s medical records and hospital laboratory register were used to retrieve semen analysis results of patients from June 2018 to June 2020. Ethical approval was obtained from the Ministry of Health Research and Ethical Review Committee. Confidentiality of patients records kept was secured and consent was obtained from study participants to use their data. Results were presented in frequency, tables and p value < 0.05 was considered significant. Results A total of 112 patients data was analyzed in the study with 49.1% were aged between 20 to 30 years. The prevalence of male factor infertility in these patients was found to be 42% and 79.5% of them had primary type of infertility. Of the study participants; 63 (56.3%), 72 (64.3%) and 70 (62.5%) had sperm count < 15 million sperms/ml, sperm motility < 40 % and morphology of < 60% respectively. One tenth, 15 (13.4%) of the patients had a semen volume of < 1.5ml/ejaculate, out of which 13(86.7%) had primary type of infertility. Moreover; 72 (64.3%) patients had total sperm count/ejaculate of < 39 million and 59 (82%) of these had primary type of infertility. In addition; 50.8% and 50% of patients aged 20 to 30 years had a sperm count < 15 million/ml and sperm motility of < 40% respectively. Conclusion The prevalence of male factor infertility was slightly higher and was dominated with primary infertility. Most patients had lower sperm count, sperm motility but higher semen volume, and majority of the patients with abnormal sperm results were aged between 20 to 30 years. Further prospective researches to determine the risk factors for male infertility and introducing assisted type of fertility in Eritrea are highly recommended.

scholarly journals Abnormal semen parameters among males in infertile couples: a cross sectional study from a tertiary care centre

2020 ◽  
Vol 9 (8) ◽  
pp. 3398
Author(s):  
Jyoti Garg ◽  
Rachana Meena ◽  
Shailaja Shukla ◽  
Sunita Sharma ◽  
Riva Choudhury
Keyword(s):  
Semen Quality ◽  
Semen Analysis ◽  
Tertiary Care ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Medical Attention ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Cross Sectional ◽  
Infertile Couples

Background: In India, the prevalence of primary infertility ranges from 3.9% to 16.8%. Male factor contributes 40-50% of this. Male factor infertility is indicated by decreased sperm concentration, reduced motility, vitality or abnormal sperm morphology. Semen analysis is the single most important investigation to detect male factor infertility. The aim of this study was to analyse the prevalence of abnormal semen parameters among males in infertile couples and their association with contributing factors.Methods: This cross-sectional hospital-based study was carried out in the Department of Pathology at Lady Hardinge Medical College and Smt. Sucheta Kriplani Hospital. A total of 400 cases were analyzed during a period of 6 months. Detailed history of the couple was taken. Semen analysis was done using automated semen analyzer (SQA-vision) after 3 days of abstinence according to the WHO 5th edition 2010 guidelines. The results were analysed using excel sheet and SPSS software.Results: In the present study, 122 cases (30.5%) out of 400 cases had abnormal semen parameters. Most common abnormality detected was asthenozoospermia (14.3%) followed by oligozoospermia (13.8%), azoospermia (10.5%) and teratozoospermia (10.5%). There was significant association of alcohol intake, obesity and trauma with abnormal semen parameters.Conclusions: Asthenozoospermia was the most common abnormality noted in this study. Lifestyle modifications along with timely medical attention in male partners of infertile couples can improve the semen quality.

scholarly journals Etiology and Risk Factors Associated With Infertility

2019 ◽  
Vol 7 (3) ◽  
pp. 346-353 ◽  
Author(s):  
Azam Moridi ◽  
Nasibeh Roozbeh ◽  
Halimeh Yaghoobi ◽  
Shirin Soltani ◽  
Sareh Dashti ◽  
...  
Keyword(s):  
Risk Factors ◽  
Medical Science ◽  
Underlying Disease ◽  
Cross Sectional Study ◽  
Male Factor ◽  
Cross Sectional ◽  
Factors Associated ◽  
Validated Questionnaire ◽  
Pregnancy And Postpartum ◽  
Common Causes

Objectives: Infertility is one of the important complications in gynecology and the aim of the present study was to investigate the etiology and risk factors associated with infertility in the southern region of Iran. Materials and Methods: This cross-sectional study was conducted in infertility centers of Hormozgan University of Medical Science (HUMS). Totally, 250 infertile couples were included. The variables including socio-demographic characteristics, smoking, body mass index (BMI), and infertility status (e.g., type of fertility, duration, etc.) were assessed by a self-administered and validated questionnaire. Data analysis was carried out using SPSS version 22.0. Results: The most common causes of male and female infertility were varicocele (49.4%) and ovulation disorders (57.5%), respectively. There was a significant association between female factor infertility and level of education, age of women, women’s age at marriage, number of abortions, alcohol consumption, presence of an underlying disease, and BMI (P<0.005). There was also a significant relationship between male factor infertility and men’s job, addiction, smoking, and presence of an underlying disease (P<0.005). Conclusions: Considering various risk factors for infertility, an important step forward can be taken towards reducing the incidence of these risk factors by providing different education classes during pre-marriage, pre-partum, pregnancy and postpartum periods so as to inform couples of controllable risk factors.

scholarly journals Comparison of ovulation induction with letrozole plus dexamethasone and letrozole alone in infertile women with polycystic ovarian disease: An RCT

2020 ◽  
Author(s):  
Farahnaz Farzaneh ◽  
Fatemeh Afshar
Keyword(s):  
Pregnancy Rate ◽  
Endometrial Thickness ◽  
Ovarian Response ◽  
Male Factor ◽  
Polycystic Ovarian Disease ◽  
Ovarian Disease ◽  
Infertile Women ◽  
Follicle Diameter ◽  
Group I ◽  
The Mean

Background: Infertility is characterized by the inability to obtain a successful pregnancy after 6 months or more with unprotected and regular intercourse. In developing countries, the incidence of infertility is 2%. The causes of infertility could be male factor or female factor, or mixed factor. Objective: This study was conducted with the aim of comparison the ovarian response to letrozole alone and letrozole plus dexamethasone in infertile women with poly cystic ovarian disease (PCOS). Materials and Methods: This randomized clinical trial was conducted on 120 infertile women with PCOS referred to Ali-Ebne-Abitaleb hospital, Zahedan, Iran from February to August 2017 into two groups: group I received letrozole alone and group II recived letrozole plus dexamethasone. The endometrial thickness, follicle diameter, and ovulation were evaluated and compared by ultrasound on days 12 to 14. Results: The mean thickness of endometrium was not different between two groups. Pregnancy rate was 8% in letrozole group and 23% in Letrozole plus Dexamethasone (p = 0.024). Also, the mean diameter of follicles in two groups were not statistically significant. Conclusion: Overall, this study showed that dexamethasone may increase pregnancy rate. Key words: Letrozole, Dexamethasone, PCOS, Induction ovulation.

scholarly journals Prevalence and associated risk factors of polycystic ovarian disease in professional college going girls of Agra City: a cross-sectional study

2021 ◽  
Vol 8 (4) ◽  
pp. 1917
Author(s):  
Neelika Tripathi ◽  
Renu Agrawal ◽  
Richa Singh ◽  
S. K. Misra ◽  
Geetu Singh
Keyword(s):  
Risk Factors ◽  
Lifestyle Modification ◽  
Emotional Health ◽  
Reproductive Age ◽  
Menstrual Irregularity ◽  
Cross Sectional ◽  
Polycystic Ovarian Disease ◽  
Ovarian Disease ◽  
Associated Risk Factors ◽  
Agra City

Background: Polycystic Ovarian Disease is the most common endocrine disorder among females of reproductive age group. This study was aimed to assess the prevalence of PCOS and its associated risk factors in girls of 18-30 years of age, studying in various professional colleges of Agra city.Methods: Sample size for this study was calculated as 1108. Girls from various professional colleges in Agra were approached (n=1280), 36 girls disagreed to give consent and 64 forms were incomplete. 1200 agreed to participate. They were asked to fill up a questionnaire asking details of menstrual cycle and features of hyperandrogenism. Anthropometric measurements like height, weight, waist and hip circumference were taken. Blood pressure was measured. A probable case was defined as a girl with menstrual irregularity or hirsutism or both. All the probable cases were asked for detailed examination, hormone estimation, and ovarian ultrasonography.Results: Of the 1200 girls, 220(18.30%) had menstrual irregularity, 101(8.40%) had hirsutism, and 65(5.40%) had both menstrual irregularity and hirsutism. After hormonal evaluation and ultrasonography, prevalence of PCOS according to Rotterdam’s criteria was found to be 16.60% .PCOS was found to be significantly associated with socioeconomic status I and II, non-vegetarian diet, snacking, inadequate physical activity, obesity and overweight, central obesity, prehypertension and hypertension, family history of PCOS and self-perceived feeling of disturbed emotional health in girls.Conclusions: An early lifestyle modification and health education among girls is required to reduce PCOS and its complications in girls. 

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