scholarly journals Clinicopathological Study of 50 Cases Colorectal Carcinoma At Tertiary Care Hospital

2013 ◽  
Vol 4 (2) ◽  
pp. 53-56
Author(s):  
Md Abdul Quddus ◽  
Md Alimunzzaman ◽  
Md Zilluar Rahman ◽  
Md Kausar Alam
Keyword(s):  
Colorectal Cancer ◽  
Colorectal Carcinoma ◽  
Rectal Carcinoma ◽  
Colonic Cancer ◽  
Tumour Size ◽  
Tertiary Care ◽  
Bowel Habit ◽  
Care Hospital ◽  
College Hospital ◽  
Serum Cea

Background: Colorectal carcinoma is a major causes of mortality and morbidity worldwide. Objective: The purpose of the present study was to consider the socio-demographic status and serum CEA level as diagnostic tool for advanced stages of colorectal cancer. Methodology: This analytical cross-sectional study was conducted in the Department of Surgery at Shaheed Ziaur Rahman Medical College Hospital, Bogra during the period of January 2010 to December 2011. Patients age ranged from 15 years to 75 years and above were included in this study. All efforts and available modern technologies including ultrasonography (USG), CT scan, endo-anal USG, chest X-ray were done to detect the primary site and metastasis of colorectal cancer. Result: The most frequent colorectal cancer was detected in 35-44 years age group with 60.0% male and 40.0% female patients. A total number of 41(82%) cases had been suffering from rectal carcinoma and 9(18%) with colonic cancer. Abdominal pain, anorexia, altered bowel habit, per rectal bleeding and abdominal lump were the cardinal features in clinical presentation. This study showed that serum CEA level was raised in 3(11.11%) cases with tumour size 2-5 cm and 21(91.30%) cases with tumor size >5cm. It was observed that serum CEA level was raised in 100% cases of Dukes stage 'D', 92.31% cases of stage 'C' and 30.56% cases of stage 'B' colorectal cancer. The serum CEA level in relation with tumour size and stage has been proved highly significant (p<0.001). Conclusion: Rectal carcinoma is found common than colonic cancer and level of serum CEA is directly related to the cancer stage. DOI: http://dx.doi.org/10.3329/jssmc.v4i2.14413 J Shaheed Suhrawardy Med Coll, 2012;4(2):53-56

scholarly journals CLINIC OPATHOLOGICAL STUDY OF COLORECTAL MALIGNANCY IN TERTIARY CARE HOSPITAL

2021 ◽  
Vol 5 (9) ◽  
Author(s):  
Ravindra Singh ◽  
Atul Ameta
Keyword(s):  
Colorectal Carcinoma ◽  
Correct Diagnosis ◽  
Tertiary Care ◽  
The United States ◽  
Bowel Habit ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
Presenting Symptoms ◽  
Loss Of Weight

Background: Colorectal carcinoma is one of the most frequent malignancies in the world. It is the second foremost cause of cancer mortality in the United States. Methods: The present study was carried out on 25 patients, being admitted to the various surgical wards ofM.B. Govt. Hospital, attached to the R.N.T. Medical College Hospital, Udaipur between the period July 2017 to November 2019 Results: The presenting symptoms in the present study were change in bowel habit (92%), bleeding per rectum (32%), and loss of weight in 60% of cases. A lump abdomen was noticed in 48% of cases, pain abdomen in 36% of cases. 16% presented with acute bowel obstruction. Conclusion: The common symptoms of constipation or constipation with diarrhoea are neglected and treated with simple laxative without elaborate investigation. Bleeding from malignant growth in the rectum is thought to be from piles and mis-treated accordingly, without doing a simple digital examination. It is emphasized that a thorough history taking, proper physical examination is must. To arrive in a correct diagnosis and plan a definite treatment. Also health education to the public in the forms of lectures, posters and audio-visual presentations will help the patient to seek medical advise at an earliest time. Keywords: Colorectal, Carcinoma, Clinical

scholarly journals Detection of Human Papilloma Virus in Colorectal Cancer by Polymerase Chain Reaction Technique in A Tertiary Care Hospital of Bangladesh

2019 ◽  
Vol 18 (1) ◽  
pp. 44-48
Author(s):  
Narayan Chandra Das ◽  
Mohammad Ismail Hossain ◽  
Saida Nasreen ◽  
Mehnaz Nasreen ◽  
Pradip Bhattacharjee ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Colorectal Carcinoma ◽  
Human Papilloma Virus ◽  
Tertiary Care ◽  
Mucinous Carcinoma ◽  
Hpv Infection ◽  
Care Hospital ◽  
Chi Square ◽  
Papilloma Virus ◽  
Medical College

Background: Human Papilloma Virus (HPV) infection is associated with the development of several cancers, including oral, esophageal, skin, lung, and uterine cervix. Association of HPV and colorectal cancers remains controversial. The aim of this study was to evaluate the association between HPV infection and colorectal cancer in Chattogram of Bangladesh. Materials and methods: The study was carried out in the Department of Pathology, Chattogram Medical College, Bangladesh over a period of one year from July, 2013 to June, 2014. A total of 60 cases were included in the study during the time period. Histopathological type and grading was done. HPV type 16 and 18 DNA was examined from all samples by means of Real Time PCR using type specific primer named E7 protein. Finally association between HPV types 16/18 with colorectal carcinoma was assessed by Chi-square (c2) test. Results: The mean age of 60 patients was 45.35 years (Range 17-75 years). Rectum was the common site of tumour 26 (43.3%). HPV type 16 and 18 was detected in 25 (41.7%) cases, out of whom 24 (96%) were associated with HPV16, and only one case was both HPV type 16 and 18. As regarding histological type, out of 25 cases 21 (84%) cases of adenocarcinoma, 3 (12%) case of signet ring carcinoma and only 1 (1.6%) case of mucinous carcinoma were positive for HPV. Conclusion: HPV specially subtype 16, may play a role in the oncogenesis of Colorectal Carcinoma. Chatt Maa Shi Hosp Med Coll J; Vol.18 (1); Jan 2019; Page 44-48

A Retrospective Descriptive Study of Pattern and Presentation of Colorectal Cancers in Shaikh Zayed Hospital Lahore

2021 ◽  
Vol 15 (11) ◽  
pp. 2993-2995
Author(s):  
Muhammad Aamir Jameel ◽  
Muhammad Imran Anwar ◽  
Muhammad Muaaz Akram ◽  
Haroon javid Majid ◽  
Sameen Tahir
Keyword(s):  
Colorectal Cancer ◽  
Colorectal Carcinoma ◽  
Tertiary Care ◽  
Age Groups ◽  
Case Series ◽  
Tumor Grade ◽  
Care Hospital ◽  
Clinical Presentations ◽  
Case Series Study ◽  
Study Methodology

Aim: To determine the distribution of gender, age and clinical presentations along with histological type of colorectal cancer in patients presented to Shaikh Zayed Hospital Lahore. Study design: This is a case series study Methodology: This retrospective study on colorectal cancer was conducted in Shaikh Zayed Hospital Lahore. Forty-four 44 patients from Jan 2018 to Jan 2021 were included of colorectal carcinoma. Data were collected and analyzed using SPSS v 23 retrospectively from hospital record. Results: 15.9% of the patients were below the age of 30 years, 31.8% were below 40 years. Male were 65.9%. Commonest presenting symptom was altered bowel habits, rectal bleeding along with weight loss and the dominating tumor grade was moderately differentiated adenocarcinoma. Conclusion: In this study colorectal carcinoma among young age groups were more commonly present at the fourth and sixth decade. Keywords: Colorectal carcinoma, Adenocarcinoma, Tertiary care hospital.

Patterns of serum CEA levels in different clinico-pathological variables of colorectal cancer

2020 ◽  
Vol 14 (2) ◽  
pp. 68-71
Author(s):  
Muhammad Hayat ◽  
Ghulam Haider ◽  
Shahid Hussain ◽  
Perwasha Kerio ◽  
Ravisha Bai ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Tertiary Care ◽  
Elevated Serum ◽  
Response To Therapy ◽  
Care Hospital ◽  
Significant Difference ◽  
Serum Carcinoembryonic Antigen ◽  
Serum Cea ◽  
Colorectal Cancer Patients

Background: Globally, colorectal malignancy is the 3rd most frequent cancer and the 2nd major cause of mortality. Serum carcinoembryonic antigen (CEA) is a simple tumor marker for the diagnosis, predicting response to therapy and survival and identifying the recurrence of colorectal cancer. Therefore, the aim was to evaluate the pattern of serum CEA levels in patients with colorectal cancer presenting at a tertiary care hospital in Karachi Patients and methods: It was a cross-sectional study conducted at the Department of Medical Oncology of Jinnah Postgraduate Medical Center, Karachi from January till August 2019. One ninety-nine patients of 12-80 years age and either gender diagnosed with colorectal cancer (biopsy-proven) were included. Data on demographics, clinical and pathological findings were recorded in the pre-designed proforma. The serum CEA levels in colorectal cancer patients were assessed using an ELISA kit. CEA levels higher than 5.0 ng/mL were deemed as elevated CEA levels in colorectal patients. Data were analyzed using SPSS version 23. Results: A total of 191 colorectal cancer patients were included. The mean age of the patients was 42.81±15.22 years. Most of the patients (61.3%) were male. Out of 191 colorectal cancer patients, 60 (31.4%) had CEA level 0-0.3 ng/ml, whereas 79 (41.4%) had elevated serum CEA level (>10 ng/ml). The CEA levels were stratified with respect to effect modifiers. The size of the tumor, TNM staging and localization and metastasis of cancer showed a statistically significant difference between levels of CEA (p<0.05). Conclusion: The raised CEA levels are associated with clinically progressive or presence of residual and recurrent disease. For patients with progressive tumors, particularly colorectal carcinoma, CEA assays are an important guide to assess the burden of the tumor, hence clinicians and surgeons ought to monitor antigen levels. It is recommended to enhance the clinical efficacy of the CEA levels.

Causes of Epilepsy in Elderly Patients Presenting in a Tertiary Care Hospital of Karachi

2020 ◽  
Keyword(s):  
Elderly Patients ◽  
Cerebrovascular Disease ◽  
Neurodegenerative Disorder ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Traumatic Head Injury ◽  
Keywords Epilepsy ◽  
College Hospital ◽  
Cross Sectional

Background: Epilepsy is fairly a frequent occurrence in the elderly. It is commonly diagnosed after the episode of two or more unprovoked seizures. Unprovoked seizures in elderly are recurrent rather than younger individuals. This study was designed to estimate the concrete burden of frequent causes of epilepsy. Methods: A descriptive cross-sectional study with a total of 153 patients diagnosed case of epilepsy were included in this study at Jinnah Medical College Hospital from February 2018-August 2018. Mean was calculated for age, duration of disease of the patients. Causes of epilepsy, gender, and education was calculated and presented as percentages. Electrolyte readings were taken i.e., Sodium, Calcium and Magnesium levels and imaging was planned to rule out stroke, primary neurodegenerative disorders and tumors. Post stratification Chi square test was applied and p-value less than or equal to 0.05 was considered significant. Results: The mean age of the patients was 63.91±5.68 years and mean duration of the disease was 4.61± 1.07 months. The common causes of epilepsy were found to be cerebrovascular disease 56.9%, cryptogenic 54.2%, neurodegenerative disorder 20.3%, traumatic head injury 11.8%, metabolic abnormalities or electrolyte disturbances 10.5% and brain tumor 7.8%. Conclusion: Elderly patients with first seizure should present to a facility designed in a way that neurologist, cardiologist, rehabilitation and geriatrics work together to identify and treat the condition in a better way. Keywords: Epilepsy; Seizures; Cerebrovascular Disease; Neurodegenerative Disorder.

scholarly journals Management of Ectopic Pregnancy in a Tertiary Care Hospital by Surgery

2016 ◽  
Vol 28 (1) ◽  
pp. 21-25
Author(s):  
Saida Akter ◽  
Sharmin Sultana
Keyword(s):  
Physical Examination ◽  
Ectopic Pregnancy ◽  
Radical Surgery ◽  
Tertiary Care ◽  
Total Abdominal Hysterectomy ◽  
Conservative Surgery ◽  
Diagnostic Tools ◽  
Care Hospital ◽  
College Hospital ◽  
Cross Sectional

Introduction: Tubal ectopics if large, uncontrollably bleeding or severely damaged need radical surgery (salpingectomy), otherwise conservative surgery (salpingotomy, salpingostomy) is the way of operative management. Laparoscopic surgery usually done in case of haemodynamically stable condition.Objective: To explore the different ways of surgical management of ectopic pregnancy in a tertiary care hospital.Materials and methods: This cross sectional study was carried out in the Department of Obstetrics and Gynaecology, Shaheed Suhrawardy Hospital and Dhaka Medical College Hospital during August 2005 and June 2006. The study population consisted of 50 women with ectopic pregnancy. Selected women underwent meticulous history taking and physical examinations. Some investigations like ultrasonography, culdocentesis, urine for pregnancy tests were done. Patients were treated by either radical or conservative surgery.Results: All (100%) women had abdominal tenderness. Ectopic pregnancy was diagnosed by history, physical examination and culdocentesis (84%), ultrasonography (12%) and laparotomy (4%). Two (4%) women were treated by conservative surgery, while the rest by radical surgery; 40 (80%) underwent unilateral salpingectomy, 3 (6%) unilateral salpingectomy with contralateral tubectomy, 2 (4%) unilateral salpingo oophorectomy, 1 (2%) total abdominal hysterectomy and 2 (4%) resection of rudimentary horn.Conclusion: Most common diagnostic tools were by history, physical examination and culdocentesis and common management was unilateral salpingectomy.Bangladesh J Obstet Gynaecol, 2013; Vol. 28(1) : 21-25

scholarly journals COLORECTAL CARCINOMA

2011 ◽  
Vol 18 (04) ◽  
pp. 566-570
Author(s):  
AYAZ GUL ◽  
SYED IFTIKHAR ALAM ◽  
RASHID ASLAM ◽  
Waqar Alam
Keyword(s):  
Colorectal Cancer ◽  
Colorectal Carcinoma ◽  
Tertiary Care ◽  
Young Patients ◽  
Age Group ◽  
Surgical Department ◽  
Male Preponderance ◽  
Histologic Types ◽  
Hospital Study

Objective: Colorectal cancer is the second commonest cause of death in the world. Its incidence in young patients is on rise. Objective: To determine the common types of colorectal carcinoma in patients below 40 years of age presenting to tertiary care level hospital. Study Design: Descriptive study Setting: It was carried out at Surgical Department, KTH, Peshawar Period: January 2007 to January 2008. Materials and methods: Total of 50 patients younger than forty years of age with colorectal cancer were included in study for the determination of histologic types. Results: There were 66% males and 34% were females. The commonest affected age group was 31-35 years old having 46% cases. On history 86% patients complained of altered bowel habits and on clinical examination anemia was present in 72% patients. Left and right sided tumors were found in 70% and 30% patients respectively. Adenocarcinoma was the commonest type found in 94% cases followed by lymphoma (4%). Conclusions: The incidence in young age group (≤ 39 years) was highest There was slight male preponderance. Adenocarcinoma was the commonest tumor.

scholarly journals VAGINAL DISCHARGE

2011 ◽  
Vol 18 (04) ◽  
pp. 598-603
Author(s):  
SHAHIDA SHAIKH ◽  
SALEEM AKHTER SHAIKH ◽  
INAYAT MAGSI
Keyword(s):  
Vaginal Discharge ◽  
Tertiary Care ◽  
Care Hospital ◽  
College Hospital ◽  
Internally Displaced ◽  
Syndromic Management ◽  
Sexually Transmitted ◽  
Medical College ◽  
Abnormal Growth ◽  
History Of

Objective: To observe the results of syndromic management in women living in IDPs camps complaining of chronic vaginal discharge. Design: Descriptive study. Setting: Medical Camps at Larkana set by Chandka Medical College Hospital for Internally Displaced Persons (IDPs) due to floods. Period: 1st September 2010 to 31st December 2010. Material and Methods: Total 200 symptomatic patients aged from 20 to 50 years suffering from chronic vaginal discharge having history of more than 6 months duration were included in the study. Asymptomatic as well as pregnant women and patients with abnormal cervix and having abnormal growth on cervix were excluded from the study. A detailed history and examination (including speculum and vaginal) was done and a proforma was filled. All these patients were given empirical treatment recommended by WHO as syndromic management consisting of stat doses of antifungal along with antibiotics, where no laboratory tests are required before treatment. Results: Next to vaginal discharge which was main symptom in all patients, the other symptoms like dusparunia, dysuria, itching ,lower abdomen pain and low backache was reported 9%, 16%, 20%, 24% and 31% respectively. Also 8% patients reported post coital bleeding. All patients were married and the mean age of the patients was 28+0.2 years and 15% of them were over 40 years. Mean parity was 4±1.Vaginal infection improved in 65% of the patients excellently with a first line single course of antibiotic and percentage raised up to 88% with second course. 19(9.5%) patients couldn’t be followed as they left that camp and 5(2.5%) patients who did not improve with two courses of antibiotics had big cervical erosions, referred to nearby tertiary care hospital for further management. Conclusions: IDPs live in poor conditions in camps without basic facilities and where it is difficult to perform bedside tests like microscopy, Potassium Hydroxide, wet mount films and tests for Sexually transmitted diseases like Chlamydia and gonorrhea are not available, syndromic management there is a rational way of treating cases of chronic vaginal discharge to get quicker response in such desperate women. 

scholarly journals Satisfaction of women with health service provider in outpatient department of Obstetrics and Gynecology at a Tertiary care hospital

2017 ◽  
Vol 6 (2) ◽  
pp. 79-81 ◽  
Author(s):  
Ashia Khatun ◽  
Khairun Nahar ◽  
Mst Nurunnahar Aktar ◽  
Fatema Mahbooba Akter ◽  
Habibur Rahman
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Hospital Environment ◽  
Obstetrics And Gynecology ◽  
Care Hospital ◽  
Health Service Provider ◽  
College Hospital ◽  
Cross Sectional ◽  
Patient’S Satisfaction ◽  
Medical College

Background: Patient's satisfaction over the health care services is very important issue in Bangladesh.Objective: The purpose of present study was to find out the level of satisfaction of women attending in the OPD of Obstetrics and Gynecology department at a tertiary care hospital in Dhaka.Methodology: This descriptive type of cross sectional study was carried out in the OPD of Obstetrics and Gynecology department at Dhaka Medical College from September 2011 to October 2011 for a period of one month. All the women attending in Obstetrics and Gynecology department in outdoor service at Dhaka Medical College Hospital, Dhaka with the age group of 22 to 40 years were selected as study population. A purposive sampling method was used to collect the data.Results: A total number of 200 cases were taken for this study. Highly satisfied over the services delivered by the doctors was reported in 135 (65.8%) cases and service of nurses was satisfied 111(55.8%) of cases. Satisfactory waiting time (two hours) was 143(7l.9%) of cases and the satisfactory hospital environment was 127 (63.8%) of cases.Conclusion: In conclusion most of the women are satisfied to the treatment delivered by the doctors at the OPD of a tertiary care hospital.J Shaheed Suhrawardy Med Coll, 2014; 6(2):79-81

scholarly journals Socio-demographic Characteristics of Vesico-vaginal fistula (VVF) patients attended at a tertiary Care Hospital in Bangladesh

2020 ◽  
Vol 6 (2) ◽  
pp. 114-117
Author(s):  
Shimul Akter ◽  
Naznin Rashid Shewly ◽  
Kashefa Khatun ◽  
Rokshana Parvin Nupur ◽  
Kamrun Nahar ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Demographic Characteristics ◽  
Medical College Hospital ◽  
Care Hospital ◽  
Vaginal Fistula ◽  
College Hospital ◽  
Medical College ◽  
The Mean ◽  
Vesico Vaginal Fistula

Background: Vesico-vaginal fistula can occur in different women with varied socio-economic condition. Objectives: The purpose of the present study was to see the socio-demographic characteristics of vesico-vaginal fistula (VVF) patients attended at a tertiary care hospital in Bangladesh. Methodology: This cross-sectional study was carried out from July 2013 to December 2013 for a period of 6 months in the National Fistula Centre in the Department of Obstetrics & Gynaecology at Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh. All patients who underwent surgical repair for iatrogenic VVF in National Fistula Centre of the department of Obstetrics and Gynaecology of Dhaka Medical College Hospital were included in this study. Patients who got themselves admitted to Obstetrics & Gynaecology department of DMCH with the complaints of fistula. The entire selected patients were interviewed for detailed socio-demographic characteristics. Result: A total number of 51 cases of VVF were recruited for this study. The mean age was 46.02 (±SD 6.104) years. Most of the respondents were illiterate (55.0%) and one-third patients had primary level education. The number of highly educated patients was scarce (12.0%). It was evident that average age at marriage of the patients was 15.8(±4.74) years. Some females were forced to accept marriage at the age of 10 years. The mean interval between initiation of menstruation and the marriage was only 4.72 years. Mothers were on an average 17.48 years old at the time of first delivery. Conclusion: In conclusion middle age illiterate women are most commonly suffering from VVF. Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 114-117

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