scholarly journals Management of Rapidly Progressing Periodontitis: An Overview

2017 ◽  
Vol 28 (1) ◽  
pp. 32-38
Author(s):  
SM Anwar Sadat ◽  
Naim Mahmud Chowdhury ◽  
Redwan Bin Abdul Baten
Keyword(s):  
Tissue Engineering ◽  
Tooth Loss ◽  
Periodontal Diseases ◽  
Aggressive Periodontitis ◽  
Regenerative Therapy ◽  
Successful Management ◽  
History Of ◽  
Rapid Destruction ◽  
Genetic Technologies ◽  
Early Tooth Loss

History of periodontal diseases recognition and treatment is ancient for at least 5000 years. There are different presentations of periodontal diseases. Rapidly progression periodontitis or aggressive periodontitis causes rapid destruction of the periodontium which leads to early tooth loss. It may be generalized or localized. Periodontitis may be treated surgically or non-surgically but patients with rapidly progressing periodontitis do not respond predictably to conventional therapy due to its multi factorial etiology. Successful management of the disease is difficult if not diagnosed early and treated appropriately. Regenerative therapy, tissue engineering and genetic technologies are the new hope for the treatment of rapidly progressing periodontitis.Medicine Today 2016 Vol.28(1): 32-38

scholarly journals Aggregatibacter actinomycetemcomitans: The virulence factors and relation to persistence biofilm formation

Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 429-435
Author(s):  
Syakir Syahiran ◽  
Wan Rohani Wan Taib ◽  
Norzawani Jaffar
Keyword(s):  
Oral Cavity ◽  
Virulence Factors ◽  
Tooth Loss ◽  
Periodontal Diseases ◽  
Aggregatibacter Actinomycetemcomitans ◽  
Aggressive Periodontitis ◽  
Essential Factor ◽  
Abiotic Surfaces ◽  
Functional Biology ◽  
Systemic Infections

Periodontitis is an infectious and inflammatory condition that is associated with subgingival biofilms in tooth-supporting tissues. Among the several hundred isolated organisms in the oral cavity, one of the most isolated bacteria from infected periodontal pockets are Aggregatibacter actinomycetemcomitans. It is a Gram-negative, facultative anaerobic bacillus that causes juvenile (localized aggressive periodontitis) and adolescent periodontal diseases. The development of biofilms is an essential factor in pathogenesis for A. actinomycetemcomitans. The early attachment of A. actinomycetemcomitans to abiotic surfaces relies on its protein-like fimbriae. This organism's ability to form tenacious biofilms can determine its survival and progression. A. actinomycetemcomitans, a pathogen not solely in periodontal but also involve in some systemic infections. This species has several virulence factors and genes that contribute to its oral cavity survival and, worst of all, cause bone resorption and tooth loss. Genetic diversity between the different A. actinomycetemcomitans isolates are great, and their ability to express and release virulence factors varies. In this review article, we discuss about the potential virulence factors and candidates genes for A. actinomycetemcomitans and their roles within periodontal disease by revealing their functional biology in facilitating attachment to oral surfaces, hindering protection of the host and causing inflammation and degradation of tissue.

scholarly journals Periodontal diseases and potential risk factors in Egyptian adult population—Results from a national cross-sectional study

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0258958
Author(s):  
Reham Khaled Abou El Fadl ◽  
Mona Ahmed Abdel Fattah ◽  
Muhammad Ahmed Helmi ◽  
Mariem Osama Wassel ◽  
Amira Saad Badran ◽  
...  
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Tooth Loss ◽  
Periodontal Diseases ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Treatment Needs ◽  
Cross Sectional ◽  
Potential Risk Factors ◽  
History Of

Background Despite the interdependence of general and periodontal health, there is paucity of national representative data on the prevalence of periodontal diseases and their associated risk factors in Egyptian population. This cross-sectional study, thus, aimed to assess the prevalence of periodontitis and tooth loss among Egyptian adults and investigate the association between potential risk factors and periodontal diseases. Methods A total of 5,954 adults aged ≥ 20 years were included in this study as a subsample from Egypt’s national oral health survey. Periodontitis was diagnosed with Community Periodontal Index ‘CPI’ scores ≥3 and tooth loss not due to caries was included in the analysis. Socio-demographic data and information on behavioral factors and history of diabetes were gathered in a face-to-face interview. Logistic regression was done to interpret the impact of potential predictors on the incidence of the two selected outcome variables. Results The overall prevalence of periodontitis was 26% and regression analysis revealed that higher odds of periodontitis existed among illiterate participants (OR = 1.74; 95% CI: 1.40–2.17), smokers (OR = 1.93; 95% CI: 1.69–2.20) and rural residents (OR = 1.16; 95% CI: 1.03–1.30). On the other hand, old age, frequency of dental attendance and history of diabetes were the main predictive factors for tooth loss. Conclusions Among Egyptian adults, periodontal diseases were strongly associated with a multitude of modifiable and non-modifiable risk factors and inequalities in distribution of periodontal treatment needs were determined mainly by age, gender, level of education and residency location.

scholarly journals Future of Decellularized Dental Pulp Matrix in Regenerative Endodontics

2022 ◽  
Author(s):  
Zohaib Khurshid ◽  
Ahmed Jamil Ahmed Alnaim ◽  
Ahmed Abdulhakim Ahmed Alhashim ◽  
Eisha Imran ◽  
Necdet Adanir
Keyword(s):  
Tissue Engineering ◽  
Dental Caries ◽  
Bone Grafting ◽  
Dental Pulp ◽  
Tooth Loss ◽  
Periodontal Diseases ◽  
Dental Tissue ◽  
Pulp Regeneration ◽  
Regenerative Endodontics ◽  
Synthetic Scaffolds

AbstractWith the advancements in tissue engineering, the repair and regeneration of oral/dental tissue are becoming possible and productive. Due to periodontal diseases, the tooth loses bone support resulting in tooth loss, but bone grafting stabilizes with new bone. It is seen that due to the progression of dental caries, pulp damage happens, and the vitality of the tooth is compromised. The current theme of dental pulp regeneration through biological and synthetic scaffolds, is becoming a potential therapy for pulp revitalization.

scholarly journals Rehabilitation of Lower Anteriors with Implant Therapy in Localized Aggressive Periodontitis

2017 ◽  
Vol 1 (1) ◽  
pp. 40-44
Author(s):  
Varshal J Barot
Keyword(s):  
Tooth Loss ◽  
Aggressive Periodontitis ◽  
Early Age ◽  
Viable Option ◽  
Implant Placement ◽  
History Of ◽  
Implant Therapy ◽  
Localized Aggressive Periodontitis ◽  
Rare Group ◽  
Severe Destruction

ABSTRACT Periodontitis is the most common, destructive, inflammatory disease of supporting tissues of the teeth in humans, with profound effects on general health. Aggressive periodontitis (AgP) comprises a rare group of population, a rapidly progressing form of periodontitis, characterized by severe destruction of periodontal attachment apparatus and tooth loss at an early age. Considering the psychological problems that these patients have faced during the early stages of their life, the main aim of treatment is to achieve functional, esthetic, and phonetic rehabilitation. Dental implant is a widely used treatment option that provides functional and esthetic resolution. Implant placement in patients with a history of AgP might be considered a viable option to restore oral function; however, the risk for implant failure is significantly higher. This report presents rehabilitation of lower anteriors with implant therapy in a 24-year-old systemically healthy male with history of localized AgP, who had previously received complete periodontal therapy for periodontal stabilization. How to cite this article Barot VJ. Rehabilitation of Lower Anteriors with Implant Therapy in Localized Aggressive Periodontitis. Int J Clin Dent Res 2017;1(1):40-44.

scholarly journals Rehabilitation of Lower Anterior Teeth with Implant Therapy in Localized Aggressive Periodontitis

2018 ◽  
Vol 9 (2) ◽  
pp. 63-68
Author(s):  
Varshal J Barot
Keyword(s):  
Tooth Loss ◽  
Inflammatory Diseases ◽  
Aggressive Periodontitis ◽  
Early Age ◽  
Viable Option ◽  
Implant Placement ◽  
Anterior Teeth ◽  
History Of ◽  
Implant Therapy ◽  
Severe Destruction

Periodontitis is the most common, destructive, inflammatory diseases of supporting tissues of the teeth in humans, with profound effects on general health. Aggressive periodontitis (AgP) comprises a rare, rapidly progressing form of periodontitis, characterized by severe destruction of periodontal attachment apparatus and tooth loss at an early age. Considering the psychological problems which these patients have during the early stages of their life, the chief aim of the treatment is to achieve functional, esthetic, and phonetic rehabilitation. Dental implant is a widely used treatment option that provides functional and esthetic resolution. Implant placement in patients with a history of AP might be considered a viable option to restore oral function; however, the risk for implant failure is significantly higher. This report presents rehabilitation of lower anterior teeth with implant therapy in a 24-year-old systemically healthy male with a history of localized AP, who had previously received complete periodontal therapy for periodontal stabilization

scholarly journals Use of mouthwashes in the treatment of chronic catarrhal gingivitis in children

2020 ◽  
Vol 5 ◽  
Author(s):  
Muzaffarov Bekzod Yunusovich ◽  
Saidov Akbar Ahadovich
Keyword(s):  
Tooth Loss ◽  
Periodontal Diseases ◽  
Aggressive Periodontitis ◽  
Young Age ◽  
Diagnosis And Treatment ◽  
Short Period ◽  
High Prevalence

Inflammatory periodontal diseases are a serious problem of modern dentistry due to the high prevalence, complexity of diagnosis, treatment and rehabilitation of patients. The least studied pathology to date is aggressive periodontitis, in which active destruction of the supporting tissues of the teeth begins at a young age and in a relatively short period of time leads to massive tooth loss [Grigoryan A. S ssoavt., 2004; Dmitrieva L. A., 2007; grudyanov A. I., 2010; Jin L. J. et al., 2011;WolfD.L., Lamster I. B., 2011; Ohrn K., Jonsson V., 2012]. The prevalence of inflammatory periodontal diseases is extremely high and reaches according to various authors from 70 to 98 %. In this regard, improving the methods of diagnosis and treatment of these diseases is a serious problem of dentistry.

Microbiological substantiation of application of phytopreparations in treatment of inflammatory periodontal diseases

2019 ◽  
Vol 24 (3) ◽  
pp. 196-202 ◽  
Author(s):  
S. A. Abdurakhmanova ◽  
G. S. Runova ◽  
M. S. Podporin ◽  
E. V. Tsareva ◽  
E. V. Ippolitov ◽  
...  
Keyword(s):  
Tooth Loss ◽  
Periodontal Diseases ◽  
Adult Population ◽  
Experimental Studies ◽  
Herbal Medicines ◽  
Growth Dynamics ◽  
Integrated Approach ◽  
Bacterial Populations ◽  
Streptococcus Constellatus ◽  
Urgent Task

Relevance: Inflammatory-destructive periodontal diseases are the most complicated and became the main cause of tooth loss in adult population. Herbal medicines have a variety of pharmacological properties, so the development and introduction of new forms for the treatment of inflammatory periodontal diseases is an urgent task today.Purpose – experimental evaluation of effectiveness of the use of herbal medicines “Tonzinal” and “CM-1” in relation to the priority periodontal pathogenes.Materials and methods: in experimental studies, the basis for the experiment was the system for the cultivation of microorganisms in real time – the Revers-Spinner RTS-1 bioreactor. With the priority strains of periodontitis pathogens, the study of the growth dynamics of the culture was carried out in several parallels.Results: herbal medicines “CM-1” and “Tonsinal” has a multilateral therapeutic effect, exerting a diverse influence on the key stages of development of such bacterial populations as Aggregatibacter actinomycetemcomitans, Streptococcus constellatus, Candida albicans.Conclusion: tan integrated approach in the treatment of patients with inflammatory periodontal diseases is promising and will contribute to a more prolonged remission and increase the effectiveness of treatment. 

Pseudogenized Amelogenin Reveals Early Tooth Loss in True Toads (Anura: Bufonidae)

2021 ◽  
Author(s):  
John Shaheen ◽  
Austin B Mudd ◽  
Thomas G H Diekwisch ◽  
John Abramyan
Keyword(s):  
Tooth Loss ◽  
Tooth Enamel ◽  
Synonymous Substitution ◽  
Bufo Bufo ◽  
Molecular Dating ◽  
Bufo Gargarizans ◽  
The Family ◽  
Synonymous Substitution Rates ◽  
Mandibular Teeth ◽  
Early Tooth Loss

Abstract Extant anurans (frogs and toads) exhibit reduced dentition, ranging from a lack of mandibular teeth to complete edentulation, as observed in the true toads of the family Bufonidae. The evolutionary timeline of these reductions remains vague due to a poor fossil record. Previous studies have demonstrated an association between the lack of teeth in edentulous vertebrates and the pseudogenization of the major tooth enamel gene amelogenin (AMEL) through accumulation of deleterious mutations and the disruption of its coding sequence. In the present study we have harnessed the pseudogenization of AMEL as a molecular dating tool to correlate loss of dentition with genomic mutation patterns during the rise of the family Bufonidae. Specifically, we have utilized AMEL pseudogenes in three members of the family as a tool to estimate the putative date of edentulation in true toads. Comparison of AMEL sequences from Rhinella marina, Bufo gargarizans and Bufo bufo, with nine extant, dentulous frogs, revealed mutations confirming AMEL inactivation in Bufonidae. AMEL pseudogenes in modern bufonids also exhibited remarkably high 86–93% sequence identity among each other, with only a slight increase in substitution rate and relaxation of selective pressure, in comparison to functional copies in other anurans. Moreover, using selection intensity estimates and synonymous substitution rates, analysis of functional and pseudogenized AMEL resulted in an estimated inactivation window of 46-60 MYA in the lineage leading to modern true toads, a timeline that coincides with the rise of the family Bufonidae.

3-Methylcyclohex-2-en-1-one and the Douglas-fir beetle (Coleoptera: Curculionidae): history of successful bark beetle pheromone treatments

2020 ◽  
Vol 153 (1) ◽  
pp. 62-78
Author(s):  
Darrell W. Ross
Keyword(s):  
Bark Beetle ◽  
Douglas Fir ◽  
Future Research ◽  
Beetle Species ◽  
Successful Management ◽  
Dendroctonus Pseudotsugae ◽  
Successful Development ◽  
History Of ◽  
Antiaggregation Pheromone

AbstractThis paper reviews the literature on the identification of 3-methylcyclohex-2-en-1-one (MCH) as the antiaggregation pheromone of the Douglas-fir beetle (Dendroctonus pseudotsugae Hopkins) (Coleoptera: Curculionidae) and the development of successful management applications using the pheromone. Previously unpublished data from two studies on novel uses of MCH are included. The successful development of antiaggregation pheromone-based treatments for the Douglas-fir beetle is discussed in relation to efforts to develop similar treatments for other bark beetle species, and opportunities for future research on MCH and the Douglas-fir beetle are suggested.

Sign in / Sign up

Export Citation Format

Share Document