scholarly journals Clinical Profile and Outcome of Acute Poisoning Cases in Children Living in a Rapidly Urbanizing Area

2021 ◽  
Vol 33 (2) ◽  
pp. 156-159
Author(s):  
Md Nurul Islam ◽  
Naimur Rahman Ringku ◽  
Md Saiful Islam
Keyword(s):  
Child Death ◽  
Complete Recovery ◽  
Acute Poisoning ◽  
Clinical Findings ◽  
Mortality And Morbidity ◽  
Male Preponderance ◽  
Study Population ◽  
Medicine Today ◽  
Etiological Agents ◽  
A Prospective Study

Introduction: Acute poisoning is a common childhood emergency in Bangladesh. In many cases history and clinical features fail to identify the offending agent. This study was done to identify the specific clinical findings related with the source of poisoning and assess the outcome. Materials and Methods: It was a prospective study done from January to June 2020, among 75 indoor children of Tangail District Hospital. A preformed structured questionnaire was filled up by data collected from direct interview with the parents or caregivers, hospital records, during clinical examination. Results: We found the mean age of the study population 5.5±1.5 years having male preponderance 1.6:1 in ratio. Kerosene 16(21.33%) and organophosphorus compound 15(20%) were the most common etiological agents and accidental (85%) was the most common mode of poisoning. Most of the cases were asymptomatic 25(33.3%). We encountered only 5(6.6%) death having 62(82.6%) complete recovery. Conclusion: Acute poisoning still remains a major cause of child death in Bangladesh. History remains the main information for early diagnosis. We should take necessary steps to prevent exposure to poisonous material in children to reduce related burden of hospitalization, mortality and morbidity. Medicine Today 2021 Vol.33(2): 156-159

scholarly journals Clinical study of geriatric dermatoses

2019 ◽  
Vol 5 (1) ◽  
pp. 128
Author(s):  
M. Vairaprabha Devi ◽  
N. C. Manikandan
Keyword(s):  
Outpatient Clinic ◽  
Healthy Life ◽  
Dermatological Examination ◽  
Number Of Patients ◽  
Male Preponderance ◽  
History Of ◽  
Study Population ◽  
Benign Tumours ◽  
General Physical ◽  
A Prospective Study

<p class="abstract"><strong>Background:</strong> Diagnosis of geriatric dermatoses is a challenging job for the Physician due to the involvement of many intrinsic and extrinsic ageing factors. The present study was done with the aim to determine the clinical profile and pattern of dermatological manifestations in elderly people aged 60 and above and to analyze the correlation of various geriatric dermatoses with systemic diseases.</p><p class="abstract"><strong>Methods:</strong> This was a prospective study done on 200 elderly individuals aged 60 years and above attending the outpatient clinic of Department of Dermatology, RGGGH and the outpatient clinic of Department of Geriatrics, RGGGH during the study period from October 2015 to September 2016.<strong> </strong>Detailed history of cutaneous complaints, present and past medical complaints were taken. A complete general, physical, systemic and dermatological examination was done in all patients and the<strong> </strong>findings were noted and analysed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Male preponderance was observed (M:F-1.8:1). Maximum number of patients (n=166) belonged to the age group of 60-69 years. Wrinkling of the skin is the commonest physiological geriatric dermatoses. Among the pathological changes, infections and infestations were observed in 27.5% of the study population. Fungal infection was the commonest among them (20%) followed by bacterial (18%) and viral (12%). Diabetes Mellitus was the commonest associated systemic ailment and was observed in about 31.5% of the study population.</p><p class="abstract"><strong>Conclusions:</strong> Geriatric dermatoses occur in the elders due to extrinsic and intrinsic ageing factors. Crinkles were the commonest physiological geriatric dermatoses and benign tumours were the commonest pathological ones. Educating the elders about proper skin care along with the early diagnosis and treatment of their cutaneous ailments would help them to lead a productive and healthy life.</p>

scholarly journals Balloon Temponade to Prevent Primary PPH in Jaundice - A Prospective Study

1970 ◽  
Vol 26 (1) ◽  
pp. 22-25
Author(s):  
Maruf Siddiqui ◽  
Maliha Rashid
Keyword(s):  
Hepatitis E Virus ◽  
Postpartum Haemorrhage ◽  
Hepatitis E ◽  
College Hospital ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Study Population ◽  
Etiological Agents ◽  
A Prospective Study ◽  
And Control

This prospective interventional study was carried out on 40 intrapartum jaundice patients admitted in the Department of Obstetrics and Gynaecology, Dhaka Medical College Hospital during January to December 2004. The purpose of the study was to evaluate the effectiveness of prophylactic intrauterine hydrostatic balloon/condom temponade in addition to other conventional methods to prevent and control postpartum haemorrhage in patients with jaundice, to detect the prevalence of different etiological agents responsible for jaundice and to assess the foeto-maternal outcome in this study group. Prophylactic intrauterine hydrostatic balloon temponade was inserted in all of the 40 cases which showed an excellent effectiveness in preventing postpartum haemorrhage in patients with jaundice. The study also showed increased prevalence of Hepatitis E virus (HEV) and a high proportion of perinatal deaths in the study population. DOI: 10.3329/jbcps.v26i1.4229 J Bangladesh Coll Phys Surg 2008; 26: 22-25

scholarly journals Clinico-Haematological Study of Pancytopenia

2021 ◽  
Vol 33 (1) ◽  
pp. 12-18
Author(s):  
Samira Taufique Reshma ◽  
Susane Giti ◽  
Shahed Ahmed Chowdhury ◽  
Mohammad Golam Rabbani ◽  
Mohammad Iqbal Kabir ◽  
...  
Keyword(s):  
Diagnostic Yield ◽  
Bone Marrow Aspiration ◽  
Armed Forces ◽  
Clinical Findings ◽  
Diagnostic Challenge ◽  
Male Predominance ◽  
Life Saving ◽  
Medicine Today ◽  
A Prospective Study ◽  
Physical Findings

Introduction: Pancytopenia is a clinical condition, which refers to a combination of anaemia, leucopenia and thrombocytopenia. It often poses diagnostic challenge to physician and the knowledge of accurate etiologies of this condition is crucial in the management of the patient. Materials and Methods: The study was a prospective study done over a period of October 2011 to December 2011 and 50 patients were evaluated clinically along with haematological parameters, bone marrow aspiration and wherever required, a trephine biopsy was performed in Haematology department of Armed forces institute of pathology (AFIP), Dhaka cantonment, Dhaka. In all patients, a detailed relevant history along with a physical examination was done and data was collected using pre designed proforma. Results: Among the 50 cases studied, age of the patients ranged from 3 to 80 yrs with a mean age of 37.5 yrs and male predominance. Fever and generalized weakness were the most common symptoms. The commonest physical findings were pallor followed by splenomegaly and hepatomegaly. Anisopoikilocytosis and relative lymphocytosis was the most prominent peripheral blood findings in patients. The commonest cause of pancytopenia was Aplastic anaemia (36%), followed by Myelodysplastic syndrome (18%), visceral leishmaniasis (12%), Megaloblastic anaemia (8%), Acute leukaemia (6%), Myelofibrosis (4%), Multiple myeloma (4%), Hypersplenism (4%), Malaria (2%). Conclusion: As a large number of pancytopenic patients have a reversible aetiology, early & proper diagnosis may be life saving. Maximum diagnostic yield can be achieved by correlation with clinical findings & laboratory parameters. Medicine Today 2021 Vol.33(1): 12-18

Addiction and Liver Disease

2014 ◽  
Vol 25 (2) ◽  
pp. 75-83
Author(s):  
Md Akmat Ali ◽  
Farida Yeasmin ◽  
MN Nag
Keyword(s):  
Liver Disease ◽  
Liver Diseases ◽  
Drug Users ◽  
Harmful Effect ◽  
Main Role ◽  
Drug Induced ◽  
Mortality And Morbidity ◽  
Other Substances ◽  
Excessive Alcohol ◽  
Medicine Today

Drug induced liver disease is a global problem. The aims of the study are to know the recreational drugs causing harmful effect on liver, epidemiology of addiction; pathophysiology and their consequences. The major findings published to date concerning different agents causing addiction and liver disease, their implications with regard to understanding disease mechanisms and their amplitude or spectrum are described. Addiction not only invites lot of sufferings to the family and the country, but also responsible for different types of liver disease including fatty liver, hepatitis and liver failure; responsible for mortality and morbidity. Among the addiction causing substances alcohol playing the main role for liver disease worldwide. Indirect effects of addiction on liver are hepatitis B, hepatitis C and their complication, mainly due to contamination of sharing needle. Majority of people in Bangladesh are life long abstainer. Excessive alcohol beverages and other substances like heroin, amphetamine are not harmless, rather they can cause serious liver diseases. There are some differences in prevalence of addiction and liver diseases among countries. Intravenous drug users are affected both directly and indirectly due to contaminated needle sharing . DOI: http://dx.doi.org/10.3329/medtoday.v25i2.17926 Medicine Today 2013 Vol.25(2): 75-83

Hybrid Endovascular Repair of Thoracoabdominal Aorta: Early Results

2014 ◽  
Vol 17 (3) ◽  
pp. 146
Author(s):  
Osman Tansel Darcin ◽  
Mehmet Kalender ◽  
Ayse Gul Kunt ◽  
Okay Guven Karaca ◽  
Ata Niyazi Ecevit ◽  
...  
Keyword(s):  
Endovascular Repair ◽  
Therapeutic Option ◽  
Complete Recovery ◽  
Aortic Aneurysms ◽  
Thoracoabdominal Aorta ◽  
Mortality And Morbidity ◽  
Early Results ◽  
The Mean ◽  
Procedural Success

<p><b>Background:</b> Thoracoabdominal aortic aneurysms (TAAA) present a significant clinical challenge, as they are complex and require invasive surgery. In an attempt to prevent considerably high mortality and morbidity in open repair, hybrid endovascular repair has been developed by many authors. In this study, we evaluated the early-term results obtained from this procedure.</p><p><b>Methods:</b> From November 2010 to February 2013, we performed thoracoabdominal hybrid aortic repair in 18 patients. The mean age was 68 years (12 men, 6 women). All of the patients had significant comorbidities. Follow-up computed tomography (CT) scans were performed at 1 week, 3 months, 6 months, and annually thereafter.</p><p><b>Results:</b> All patients were operated on in a staged procedure and stent graft deployment was achieved. Procedural success was achieved in all cases. All patients were discharged with complete recovery. No endoleaks weres detected in further CT examination.</p><p><b>Conclusion:</b> Our results suggests that hybrid debranching and endovascular repair of extensive thoracoabdominal aneurysms represents a suitable therapeutic option to reduce the morbidity and mortality of TAAA repair, particularly in those typically considered at high risk for standard repair.</p>

scholarly journals Clinical Profile of Acute Poisoning in Children at a Teaching Hospital in Lalitpur

2014 ◽  
Vol 34 (2) ◽  
pp. 100-103 ◽  
Author(s):  
Ajaya Kumar Dhakal ◽  
D Shrestha ◽  
A Shakya ◽  
SC Shah ◽  
H Shakya
Keyword(s):  
Teaching Hospital ◽  
Hospital Admissions ◽  
Acute Poisoning ◽  
Childhood Mortality ◽  
Age Group ◽  
Common Cause ◽  
Mortality And Morbidity ◽  
History Of ◽  
The Common ◽  
Poisoning In Children

Introduction: Acute poisonings are one of the common cause of emergency visits and hospital admissions and is potentially preventable cause of childhood mortality and morbidity. The objectives of this study were to identify the common type of poisoning in children, to determine types of poisoning according to age and to find out the common age group in which the incidence of poisoning was high.Materials and Methods: It was a descriptive observational study done in a teaching hospital in Lalitpur, Nepal in patients aged 1 month to 18 years who visited the emergency department and were admitted to hospital with history of alleged poisoning from 2009 July to 2014 January.Results: Fifty patients were included. Drugs, kerosene and organophosphorus were most common cause of poisoning. Drugs and kerosene below 10 years of age and organophosphorus and drugs above 10 years of age were common types of poisoning. Maximum numbers (50%) of children with poisoning cases were below five year of age. Mean duration of hospital stay was 2.1days and mean age of poisoning was 7.8 years with a male(54%) predominance. Majority of poisoning occurred at home (84%) and 68% of patients were symptomatic at presentation to hospital with 84% of patients presenting to hospital within six hours.Conclusion: This study showed that drugs, kerosene and organophosphorus were most common forms of poisoning. Young children were most vulnerable for acute poisoning.DOI: http://dx.doi.org/10.3126/jnps.v34i2.10139J Nepal Paediatr Soc 2014;34(2):100-103 

scholarly journals A Prospective Study of Etiological Agents Among Febrile Patients in Sierra Leone

2021 ◽  
Author(s):  
Han Wang ◽  
Jing Zhao ◽  
Na Xie ◽  
Wanxue Wang ◽  
Ruping Qi ◽  
...  
Keyword(s):  
Prospective Study ◽  
Sierra Leone ◽  
Etiological Agents ◽  
A Prospective Study

scholarly journals Epidemiological and clinical characteristics of immunocompromised patients infected with Pneumocystis jirovecii in a twelve-year retrospective study from Norway

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Stine Grønseth ◽  
Tormod Rogne ◽  
Raisa Hannula ◽  
Bjørn Olav Åsvold ◽  
Jan Egil Afset ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Fold Increase ◽  
Epidemiological Data ◽  
Opportunistic Pathogen ◽  
Incidence Rates ◽  
Clinical Findings ◽  
Pneumocystis Jirovecii ◽  
Common Denominator ◽  
Study Population ◽  
Cardinal Symptoms

Abstract Background Pneumocystis pneumonia (PCP) severely menaces modern chemotherapy and immunosuppression. Detailed description of the epidemiology of Pneumocystis jirovecii today is needed to identify candidates for PCP-prophylaxis. Methods We performed a 12-year retrospective study of patients with P. jirovecii detected by polymerase chain reaction in Central Norway. In total, 297 patients were included. Comprehensive biological, clinical and epidemiological data were abstracted from patients’ medical records. Regional incidence rates and testing trends were also assessed. Results From 2007 to 2017 we found a 3.3-fold increase in testing for P. jirovecii accompanied by a 1.8-fold increase in positive results. Simultaneously, regional incidence rates doubled from 5.0 cases per 100,000 person years to 10.8. A majority of the study population had predisposing conditions other than human immunodeficiency virus (HIV). Hematological (36.0%) and solid cancers (25.3%) dominated. Preceding corticosteroids were a common denominator for 72.1%. Most patients (74.4%) presented with at least two cardinal symptoms; cough, dyspnea or fever. Main clinical findings were hypoxia, cytopenias and radiological features consistent with PCP. A total of 88 (29.6%) patients required intensive care and 121 (40.7%) suffered at least one complication. In-hospital mortality was 21.5%. Three patients (1.0%) had received prophylaxis. Conclusions P. jirovecii is re-emerging; likely due to increasing immunosuppressants use. This opportunistic pathogen threatens the life of heterogenous non-HIV immunosuppressed populations currently at growth. Corticosteroids seem to be a major risk factor. A strategy to increase prophylaxis is called for.

scholarly journals Typical and atypical CT chest imaging findings of novel coronavirus 19 (COVID-19) in correlation with clinical data: impact on the need to ICU admission, ventilation and mortality

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Doaa M. Emara ◽  
Nagy N. Naguib ◽  
M. A. Moustafa ◽  
Salma M. Ali ◽  
Amr Magdi El Abd
Keyword(s):  
Pleural Effusion ◽  
Complete Recovery ◽  
Clinical Findings ◽  
Mediastinal Lymphadenopathy ◽  
Imaging Features ◽  
Imaging Findings ◽  
Icu Admission ◽  
Mortality Outcome ◽  
Novel Coronavirus ◽  
Contrast Ct

Abstract Background The aim of this study was to highlight the typical and atypical chest CT imaging features at first presentation in 120 patients who were proved to be COVID-19 by PCR and to correlate these findings with the need for ICU admission, ventilation, and mortality. We retrospectively included 120 patients 71 males (59.2%) and 49 females (40.8%) with a mean age of 47.2 ± 14.4 years. Patients subjected to clinical assessment, CBC, PCR for COVID-19, and non-contrast CT chest at first presentation. Typical and atypical imaging findings were reported and correlated with the clinical findings of the patients, the need for ICU admission, ventilation, and mortality. Results Clinically, fever was seen in 112 patients followed by dry cough in 108 patients and malaise in 35 patients. The final outcome was complete recovery in 113 cases and death in 7 cases. Typical CT findings included bilateral peripheral ground-glass opacities (GGO) in 74.7%, multilobar affection in 92.5% while atypical findings such as homogeneous consolidation, pleural effusion, mediastinal lymphadenopathy, and single lobar affection were found in 13.4, 5, 6.7, and 7.5% respectively. A statistically significant association between the presence of white lung, pleural effusion, peripheral GGO, and the need for ICU admission as well as mechanical ventilation was noted. The death was significantly higher among elderly patients; however, no significance was found between the imaging features and mortality. Conclusion CT features at first presentation can predict the need for ICU admission and the need for ventilation but cannot predict the mortality outcome of the patients.

scholarly journals Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study

Blood ◽  
2009 ◽  
Vol 113 (22) ◽  
pp. 5412-5417 ◽  
Author(s):  
Ola Landgren ◽  
Robert A. Kyle ◽  
Ruth M. Pfeiffer ◽  
Jerry A. Katzmann ◽  
Neil E. Caporaso ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Monoclonal Gammopathy ◽  
Population Based ◽  
Serum Samples ◽  
M Proteins ◽  
Cancer Screening Trial ◽  
Risk Of Progression ◽  
Study Population ◽  
A Prospective Study ◽  
Undetermined Significance

Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma-cell proliferative disorder associated with a life-long risk of progression to multiple myeloma (MM). It is not known whether MM is always preceded by a premalignant asymptomatic MGUS stage. Among 77 469 healthy adults enrolled in the nationwide population-based prospective Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, we identified 71 subjects who developed MM during the course of the study in whom serially collected (up to 6) prediagnostic serum samples obtained 2 to 9.8 years prior to MM diagnosis were available. Using assays for monoclonal (M)–proteins (electrophoresis/immunofixation) and kappa-lambda free light chains (FLCs), we determined longitudinally the prevalence of MGUS and characterized patterns of monoclonal immunoglobulin abnormalities prior to MM diagnosis. MGUS was present in 100.0% (87.2%-100.0%), 98.3% (90.8%-100.0%), 97.9% (88.9%-100.0%), 94.6% (81.8%-99.3%), 100.0% (86.3%-100.0%), 93.3% (68.1%-99.8%), and 82.4% (56.6%-96.2%) at 2, 3, 4, 5, 6, 7, and 8+ years prior to MM diagnosis, respectively. In approximately half the study population, the M-protein concentration and involved FLC-ratio levels showed a yearly increase prior to MM diagnosis. In the present study, an asymptomatic MGUS stage consistently preceded MM. Novel molecular markers are needed to better predict progression to MM in patients with MGUS.

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