scholarly journals Modern ideas about cluster headache. Literature review

2019 ◽  
Vol 2 (19) ◽  
pp. 19-23
Author(s):  
A. Savitskaya ◽  
E. G. Filatova

The article presents a review of the literature where, starting with the publication of Ekbom K. (1947), the history of the allocation of cluster headache into a separate form of primary head pain is described, modern diagnostic criteria are presented, the pathogenesis, clinical features of the disease are described. It is shown that due to the rarity of this type of headache and low awareness of doctors, the delay in diagnosis is on average 6–7 years. Patients are prescribed a lot of unnecessary examinations and expert consultations: oculists, ENT doctors, neurosurgeons, psychiatrists, etc. Favorite incorrect diagnoses are migraine and trigeminal neuralgia. The evidence of the leading role of the hypothalamus in the pathogenesis of cluster headache is presented. The principles of therapy are discussed: for the relief of acute attacks, triptans are used as in migraine, the leader of prophylactic therapy is a calcium channel blocker verapamil. In chronic forms and attacks resistant to pharmacological treatment, neurostimulation methods are used.

2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Shadi Rezai ◽  
Stephen LoBue ◽  
Daniel Adams ◽  
Yewande Oladipo ◽  
Ramses Posso ◽  
...  

Background.Tuberculosis (TB) is a disease that affects hundreds of millions of people across the world. However, the incidence in developed countries has decreased over the past decades causing physicians to become unfamiliar with its unspecific symptoms. Pregnant individuals are especially difficult because many symptoms of active TB can mimic normal physiological changes of pregnancy. We present a case report of a 26-year-old multiparous woman, G4P3003, at 38-week gestation with a history of positive PPD who emigrated from Ghana 6 years ago. She came to the hospital with an initial complaint of suprapubic pain, pressure, and possible leakage of amniotic fluid for the past week. Patient also complained of a productive cough for the past 3 to 4 months with a decrease in vision occurring with the start of pregnancy. Visual acuity was worse than 20/200 in both eyes. Definitive diagnosis of active TB was delayed due to patient refusal of chest X-ray. Fortunately, delay in diagnosis was minimized since patient delivered within 24 hours of admission. Active TB was confirmed with intraocular dissemination. Patient had optic atrophy OS (left eye) and papillitis, choroiditis, and uveitis OD (right eye) due to TB infiltration. Fetus was asymptomatic and anti-TB therapy was started for both patients.


2010 ◽  
Vol 51 (3) ◽  
pp. 391-409
Author(s):  
MILES LARMER

ABSTRACTZambia's unsuccessful coup attempt in 1980 was initiated by members of the country's intellectual and business elite, who had played a leading role in the postcolonial civil service and state bureaucracy, but who became disillusioned with the takeover of the state by the ruling party before and after the declaration of the one-party state in 1972. Among their number was Valentine Musakanya, one of those convicted for the coup attempt. Using Musakanya's biographical and other writings, this article explores his intellectual trajectory from head of the civil service to political prisoner. In so doing, it investigates the role of life writing in aiding understanding of the postcolonial political history of Africa.


2020 ◽  
Vol 67 (3) ◽  
pp. 60-66
Author(s):  
Sh. Demissenova ◽  

The article considers the issues related to the role, features of social and pedagogical consulting in the field of ethnic relations and the requirements for the consultant himself. The history of counseling on the problems of interethnic relations, ethical and emic approaches to counseling are briefly described. The features of the consultation process in consulting on the problems of ethnic relations. The interrelation of positive ethnic identity and tolerance, ethnocultural competence of a person is revealed. The leading role of positive ethnic identity of the client's personality in overcoming ethnic problems has been determined. The role of the consultant is revealed. The requirements for a consultant, for his training and experience are analyzed. The factors that determine the effectiveness of consulting are considered. The actual problems of consulting on the problems of ethnic relations are analyzed. Practical recommendations for consultants based on a theoretical overview, are listed. The experience of social and pedagogical consultations initiated and organized by the Council of Mothers to the Assembly of the People of Kazakhstan Kostanay’s region has been summarized. The most typical requests for consulting are analyzed. The problems and prospects of implementation such a practice are described.


2021 ◽  
Vol 5 (01) ◽  
pp. 1-9
Author(s):  
Mohammad Rafiq Khan

Although the history of immobilized enzymes and their applications in different fields are traced back to the second half of the twentieth century, their importance in bioreactors and biosensors highlighted at the turn of the current century is under active consideration in these days for broad-spectrum applications in different medical fields. Thus, this article presents a review of the literature concerning the current and future role of the immobilized enzymes in different medical fields. As the author and his supervised research groups have also been actively involved in research on immobilized enzymes, he has also made some input with a recommendation to revise the current classification of immobilized enzymes basically into “Naturally Immobilized” and “Artificially Immobilized Enzymes”, keeping the sub-classification intact. He has also suggested the development of some medical products based on the results of his research groups.


2020 ◽  
pp. 90-109
Author(s):  
Nikita Istomin

This article analyzes the model of participation of many interested parties in governance of the Internet, as well as its definition on the international level and within the doctrine. The goal consists in determining the importance and the role of participation of multiple interested parties in the context of Internet governance, and its correlation to the transnational approach in international law. The model of participation of multiple interested parties is predominantly examined as participation in Internet governance of the actors of international law and private entities. The subject of this research is the provisions of summary documents, summits on the highest level regarding the questions of information community, resolution of the UN General Assembly and other branches of the UN system, provisions of acts of other transnational organizations that are dedicated to development of state policy in the area of Internet governance, as well as doctrinal sources covering history of the question. The scientific novelty lies in determination of correlation of the participation of interested parties in Internet governance. It is noted that in the practice of Internet governance there are two clear approaches for implementation of this model: ran by states and international organizations, or one that is ran by private entities. The international legal acts reflect the former approach towards implementation of this model. In accordance with this approach, the work on Internet governance in consultation of state with private entities, allowing private entities as observers, or creation of public-private partnerships aimed at solution of global issues. The leading role of the private sector is advanced by the United States and several other Western nations as an alternative to translational multilateral approach, which contradicts the international legal acts, since the role ICANN as a leader is delegated to private entities, rather than states.


2017 ◽  
Author(s):  
Lyudmila Grudtsyna ◽  
Alyeksandr CHyernyavskiy ◽  
Dmitriy Pashentsev

The monograph is devoted to the study of the role of government in shaping, support and development of Russia´s civil society institutions. by the authors E practical examples and using the theoretical and legal structures proved the leading role of the state in the formation of Russian civil society, which is based in Russia "from below", according to the classical western models, and "from above", taking into account the centuries-old traditions and the history of the Russian people and the Russian statehood. The state acts as the management system in relation to civil society as a managed system. However, civil society functions as a self-regulating social system, the determining state. The fact that civil society - self-regulating system, and at the same time controlled, there is no contradiction. The book will be of interest to lawyers, political scientists, sociologists, public servants, students, graduate students and faculty of liberal arts colleges and faculties, as well as all interested in the development of civil society in Russia and the role of the state in this process.


2011 ◽  
Vol 26 (S2) ◽  
pp. 1469-1469
Author(s):  
A. Paraschakis ◽  
G. Molochas

AimTo impress the diversity of positive symptoms in patients with schizophrenia.MethodCase report and review of the literature (PubMed).ResultsMale patient, 43 years old, single, elementary school graduate, living with his mother. First hospitalization.Clinical featuresPersecutory ideas and auditory hallucinations dating from 8 months: he was convinced that his neighbor wanted to harm him; for this reason he had recruited his dog. He noted that the dog was following him when he was going out in the neighborhood, and was very aggressive towards him (he“heard” the dog barking at him continuously). His fear made him stop working (scrap dealer) and he was afraid of coming out of his home. He had even thought of poisoning the animal. Laboratory as well as neuroimaging exams (EEG, brain CT) were normal. The patient was treated with haloperidol (30 mg daily) and olanzapine (15 mg daily). He was discharged after 18 days. Three months later, he spontaneously stopped medication (15 mg olanzapine daily); in three weeks time the same ideas had resurfaced and was “hearing” the neighbor's dog barking again loudly at him. Since then he takes his medication regularly without experiencing any symptoms. Only one relevant article was found in the literature (Dening, T.R., and West, A.“The Dolittle phenomenon: hallucinatory voices from animals”, Psychopathology. 1990; 23: 40–45).ConclusionsAnimals could, rarely, play a key role in the delusional ideas of patients with schizophrenia. This doesn’t make these ideas less debilitating or even potentially dangerous.


Author(s):  
Tatyana P. Filippova ◽  
◽  
Nina G. Lisevich ◽  

On the basis of a wide range of sources, the research analyzes the history of the study of permafrost in the territory of the European Northeast of Russia in the first half of the 20th century. The documentary sources revealed in the Archive of the Russian Academy of Sciences (Moscow), the National Archive of the Komi Republic (Syktyvkar), the Scientific Archive of the Komi Science Center of the Ural Branch of the Russian Academy of Sciences (Syktyvkar), the Vorkuta Museum and Exhibition Center (Vorkuta) are introduced into the scientific use for the first time. The 1920s became the period of the birth of a new scientific direction – permafrostology. This science gave an impetus to the systematic study and development of the North and the Arctic. The beginning of systematic geocryologic studies was connected with the development of the European Northeast in the 1920s–1930s. It has been determined that the USSR Academy of Sciences played the leading role in carrying out these studies: it organized special scientific expeditions for studying the cryolithozone of this region. The main results of the studies and their motives interconnected with the government’s interests in the development of valuable northern mineral resources are shown. The results of the expeditions were conclusions about the possibility of constructing large industrial facilities in the regions of the explored reserves of natural raw material resources. Following scientists’ recommendation, the industrial development of the Pechora coal basin and the colonization of the polar region began. The climatic and natural features of the region demanded stationary scientific research in the field of design and construction. The Vorkuta Research Permafrost Station (VRPS) (1936–1958), created under the supervision of the USSR Academy of Sciences, began to carry out this research. Today, the history of this station’s activities is poorly studied. The article presents the main directions of VRPS research: engineering permafrostology and general issues of permafrost studies. The staff of the station were researchers of the Committee on Permafrost Studies of the USSR Academy of Sciences and scientists from among prisoners of GULAG. The role of the staff who made a great contribution to permafrost studies is shown. Under the leadership of the scientists of the station, on the basis of their techniques, large industrial structures of Vorkuta District and Vorkuta, among them the first railroad in the conditions of permafrost, were designed. The conclusion is drawn on the leading role of scientists of the USSR Academy of Sciences in carrying out studies of permafrost soil in the European Northeast in the first half of the 20th century which became the basis in the successful solution of construction problems in the Arctic territory.


2021 ◽  
pp. 100-108
Author(s):  
N. V. Vashchenko ◽  
A. M. Uzhakhov ◽  
Ju. E. Azimova

Trigeminal autonomic cephalalgias (TACs) are rare but are the most intense primary headaches that severely limit patients’ ability to work and be socially active. This article reviews the modern classification of TACs, based on the International Classification of Headache Disorders-3, and the key differences between TAC types, as well as the pathophysiological mechanisms – the role of the trigeminovascular system, autonomic nervous system, hypothalamus and vagus nerve – and their relation to circadian rhythms. The sleep disturbances that can occur in patients with TACs, exacerbating the course of the disease, and the role of melatonin, hypothalamus and suprachiasmatic nucleus in these conditions are also discussed. In addition, current therapies for cluster headache are described, which include acute therapy and prophylactic therapy, with recommendations regarding the timing of prophylactic therapy discontinuation. The review also includes the available data on melatonin as well as new therapies such as CGRP monoclonal antibodies and neuromodulation, which includes the two most promising techniques: non-invasive vagus nerve stimulation and sphenopalatine ganglion microstimulation. Furthermore, the authors present the clinical case of a patient with chronic cluster headache, which was significantly reduced in frequency and intensity when melatonin was added to the therapy.


2016 ◽  
Vol 15 (4) ◽  
pp. 17-29
Author(s):  
Yu. S. Astakhov ◽  
D. M. Nefedova ◽  
V. A. Turgel

This article contains a review of the literature on the issue of migraine and glaucoma interrelation. At the present time, despite the controversial nature of the results of global research, we can talk about an authentic increase of glaucoma risk in patients with a history of migraine. It is assumed a significant role of the primary vascular dysregulation in the pathogenesis of both diseases. Also we considered the issue of increasing the risk of angle-closure glaucoma during a migraine therapy with anticonvulsant called «Topiramate».


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