Objective To examine the association between maternal education level
and live birth after in vitro fertilization (IVF). Design Retrospective
cohort study. Setting Public fertility center in China. Population 41546
women who underwent the first cycle of fresh or frozen-thawed embryo
transfer between 2014 and 2019. Methods The women were divided into four
educational categories according to the level of education received
(elementary school graduate or less, middle school graduate, high school
graduate, college graduate or higher). Main outcome measures Live birth
rates. Results Patients were grouped by maternal educational level:
elementary school graduate or less (n=1590), middle school graduate
(n=10996), high school graduate (n=8354), and college graduate or higher
(n=20606). The live birth rate, miscarriage rate, and clinical pregnancy
rate in elementary school graduate or less were lower compared to other
groups. In multivariate logistic regression analysis, we fail to
demonstrate a statistically significant relationship between educational
level and live birth in middle school graduate (adjusted odds ratio
[AOR] 0.96; 95% confidence interval [CI], 0.84-1.09), high
school graduate (AOR 1.01; 95% CI, 0.87-1.14) or college graduate or
higher (AOR 1.01; 95% CI, 0.88-1.14) patients compared with the
elementary school graduate or less reference group after adjusting for
female age, infertility duration, BMI, EM thickness, no. of oocyte
retrieved, infertility type, protocol in the fresh cycle, fertilization
type, time of transfer and no. of embryo transferred. Conclusion No
statistically significant relationship was identified between
educational level and live birth in patients undergoing fresh or frozen
embryo transfer.