Introduction. Today, there are not enough studies demonstrating the relationship between body composition disorders in men with excess adipose tissue and metabolic syndrome (MS), depending on the content of testosterone, estradiol, sex hormone binding globulin (SHBG), anthropometric parameters, or blood pressure (BP).Aim: to study the relationship between disturbances in anthropometric parameters, the level of sex hormones and BP in men with MS.Materials and Methods. The study included 64 overweight men. The patients were divided into 3 groups depending on the body mass index (BMI): group 1 with overweight (n = 24), group 2 with the first degree of obesity (n = 21), group 3 with the second and third degrees of obesity (n = 19). A correlation analysis was carried out between the results of bioimpedance analysis (BIA) and laboratory data, and the level of difference between the groups under consideration was determined.Results. The relationship was revealed between the parameters of body composition in men with overdeveloped adipose tissue and MS, depending on the level of testosterone, estradiol, SHBG, anthropometric parameters and blood pressure indicators. A moderate negative correlation was observed across the sample between the testosterone level and a number of anthropometric indicators: waist circumference (WC), OT/hip circumference (HC) and BMI (p < 0.05). A weak negative correlation was found between the level of testosterone, fat mass (FM) and the proportion of FM in the general sample. A weak negative correlation between SBP and testosterone across the sample found, while in group 3 – a moderate negative correlation. A positive weak correlation was found between testosterone and estradiol in the general sample and in group 2. In group 1, this correlation is moderately positive and in t group 3 – a negative weak correlation. A positive correlation can be traced between testosterone and SHBG: moderate in the entire sample, in groups 1 and 2, and noticeable in group 3.Conclusion. The relationship was revealed between the parameters of body composition in men with excess adipose tissue and MS, depending on the content of testosterone, estradiol, SHBG, anthropometric parameters and ВР. This confirms the consistency and multicomponent nature of the obesity problem.