scholarly journals Relationship of Fat Mass Index and Fat Free Mass Index With Body Mass Index and Association With Function, Cognition and Sarcopenia in Pre-Frail Older Adults

2021 ◽  
Vol 12 ◽  
Author(s):  
Reshma Aziz Merchant ◽  
Santhosh Seetharaman ◽  
Lydia Au ◽  
Michael Wai Kit Wong ◽  
Beatrix Ling Ling Wong ◽  
...  

BackgroundBody mass index (BMI) is an inadequate marker of obesity, and cannot distinguish between fat mass, fat free mass and distribution of adipose tissue. The purpose of this study was twofold. First, to assess cross-sectional relationship of BMI with fat mass index (FMI), fat free mass index (FFMI) and ratio of fat mass to fat free mass (FM/FFM). Second, to study the association of FMI, FFMI and FM/FFM with physical function including sarcopenia, and cognition in pre-frail older adults.MethodsCross-sectional study of 191 pre-frail participants ≥ 65 years, 57.1% females. Data was collected on demographics, cognition [Montreal Cognitive Assessment (MoCA)], function, frailty, calf circumference, handgrip strength (HGS), short physical performance battery (SPPB) and gait speed. Body composition was measured using InBody S10. FMI, FFMI and FM/FFM were classified into tertiles (T1, T2, T3) with T1 classified as lowest and T3 highest tertile respectively and stratified by BMI.ResultsHigher FFMI and lower FM/FFM in the high BMI group were associated with better functional outcomes. Prevalence of low muscle mass was higher in the normal BMI group. FMI and FM/FFM were significantly higher in females and FFMI in males with significant gender differences except for FFMI in ≥ 80 years old. Small calf circumference was significantly less prevalent in the highest tertile of FMI, FM/FMI and FFMI. Prevalence of sarcopenic obesity and low physical function (HGS, gait speed and SPPB scores) were significantly higher in the highest FMI and FM/FFM tertile. Highest FFMI tertile group had higher physical function, higher MoCA scores, lower prevalence of sarcopenic obesity and sarcopenia, After adjustment, highest tertile of FFMI was associated with lower odds of sarcopenia especially in the high BMI group. Highest tertile of FM/FFM was associated with higher odds of sarcopenia. Higher BMI was associated with lower odds of sarcopenia.ConclusionFFMI and FM/FFM may be a better predictor of functional outcomes in pre-frail older adults than BMI. Cut-off values for healthy BMI values and role of calf circumference as a screening tool for sarcopenia need to be validated in larger population. Health promotion intervention should focus on FFMI increment.

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Briana Nyemchek ◽  
Lucy Quigley ◽  
Sonja Molfenter ◽  
Kathleen Woolf

Abstract Objectives The older adult population is increasing worldwide, placing significant burden on healthcare and support systems. Meeting nutrition and physical activity guidelines is critical to maintain health and quality of life (QOL). The objective of this study was to assess nutrition, swallowing, body composition, and physical function in community-dwelling seniors (CDSs) and describe the prevalence of poor status. Methods CDSs (n = 54; 42 female; age = 80.1 ± 6.7; body mass index [BMI] = 25.2 ± 4.1 kg/m2) participated in a wellness visit to assess a) nutrition (Dietary Screening Tool [DST], an instrument that identifies nutritional risk), b) swallowing (90 ml water swallow challenge; EAT-10 swallowing screening tool) c) body composition (waist circumference; calf circumference; body fat mass index [BFMI]; fat-free mass index [FFMI]), and d) physical function (SARC-F, a five item sarcopenia screener; Short Physical Performance Battery [SPPB], testing balance, gait speed, and sit to stand). Height was measured using a portable stadiometer; weight with a Seca digital scale. Waist and calf circumferences were measured in triplicate. Body composition was assessed via bioelectrical impedance analysis using the Quad Scan 4000 multifrequency analyzer (BodyStat). BFMI (fat mass, kg/[height, m]2) and FFMI (fat-free mass, kg/[height, m]2) were determined. Results The DST revealed that 11(20.4%) and 35(64.8%) of the CDSs were “at risk” and “possible risk” for poor nutritional status, respectively. Although the EAT-10 documented swallowing difficulties in 5(9.3%) of the CDSs, 12 (22.2%) failed the 90 ml water swallow challenge, consistent with risk of swallowing impairment. Excess adiposity was found in 31(57.4%) using waist circumference and 30(55.6%) using BFMI. Low muscle mass, captured by FFMI, was found in 35(64.8%) of the CDSs. Calf circumference values revealed malnutrition in 3(5.6%) of the CDSs. Six (11.1%) of the CDSs had SARC-F scores associated with poor physical function indicating significant muscle loss in aging. Similarly, SPPB results revealed 14(25.9%) had poor lower extremity physical function. Conclusions CDSs exhibit impairments in these measures of wellness, placing their health and QOL at risk. Research examining the impact of lifestyle interventions on these measures is needed. Funding Sources None


2020 ◽  
Vol 12 (23) ◽  
pp. 9894
Author(s):  
Ana Moradell ◽  
David Navarrete-Villanueva ◽  
Ángel Iván Fernández-García ◽  
Lucía Sagarra-Romero ◽  
Jorge Marín-Puyalto ◽  
...  

The aging of humans is associated with body composition and function deterioration creating a burden on an individual level, but also on a societal one, resulting in an economic burden that is socially unsustainable. This study aimed to evaluate changes in body composition after a 6-month MCT (multicomponent training) and a 4-month detraining period, and to examine the possible influence of energy and macronutrient intake in these changes in frail and pre-frail older adults. A total of 43 participants from the training group (TRAIN) and 28 controls (CON) completed the study protocol. Body weight, body mass index (BMI), waist and hip circumferences, fat mass, fat free mass and fat mass percentage were recorded, with a bio-electrical impedance analyzer, at baseline, after 6 months and four months after finishing the MCT. A food frequency questionnaire was used to estimate energy intake. Mixed effect models did not show differences between groups. CON showed increases in hip circumference and waist (3.20 ± 1.41 and 3.06 ± 1.66 cm, respectively) during the first 6 months. TRAIN showed decreases in BMI (−0.29 ± 0.14), fat mass (−0.86 ± 0.38 kg), body fat percentage (−0.98 ± 0.36%) and increases in waist circumference (3.20 ± 1.41). After detraining, TRAIN group showed increases in fat mas (1.07 ± 0.30 kg), body fat percentage (1.43 ± 0.31%) and waist (3.92 ± 1.38 cm), and decreases in fat free mass (−0.90 ± 0.30 kg). CON group only showed an increase in body fat (1.32 ± 0.47%). Energy intake was negatively associated with hip circumference in the first six months and fat mass during detraining in CON. Energy intake showed positive associations with fat mass in TRAIN during detraining. Only carbohydrates were negatively related to detraining changes in fat free mass and BMI in CON. In conclusion, the MCT reduces adiposity of frail and pre-frail older people, leading to a maintenance of fat free mass. In addition, these interventions should not be stopped in this population in order to improve health sustainability.


2014 ◽  
Vol 46 ◽  
pp. 134
Author(s):  
Maria Giné-Garriga ◽  
Marta Roqué-Fíguls ◽  
Laura Coll-Planas ◽  
Mercè Sitjà-Rabert ◽  
Carme Martin-Borràs

2020 ◽  
Author(s):  
Nasim Ghodoosi ◽  
Atieh Mirzababaei ◽  
Elahe Rashidbeygi ◽  
Negin Badrooj ◽  
Seyedeh Forough Sajjadi ◽  
...  

Abstract Objective: Although, several studies have illustrated that there is a relation between the between dietary inflammatory index (DII) with obesity-related parameters, and inflammation, their results were controversial results. This study aimed to investigate this relationship among Iranian women. Results: Multivariable linear regression showed that fat mass was 0.14 kg lower in the anti-inflammatory diet group, with respect to the pro-inflammatory group, after adjusting covariates such as age, physical activity, economic and job status (β = -0.142, 95% CI -4.44, -1.71, P = 0.03). Fat-free mass (FFM) was 1.5 kg more in the anti-inflammatory diet group, compared to the pro-inflammatory diet group, after adjusting for potentials cofounders (β = 1.50, 95% CI 0, 3.01, p = 0.05). Furthermore, after adjusting for potentials cofounders, it was revealed that the subjects with lower DII had lower monocyte chemoattractant protein-1 (MCP-1) levels in serum (β = -18.81, 95% CI -35.84, -1.79, p = 0.03). These findings suggest an inverse and significant relationship between DII and FFM and also DII is directly related to Fat mass and the level of MCP-1. This finding can be used for developing interventions that aim to promote healthy eating to prevent inflammation and non-communicable disease development among obese female.


2021 ◽  
Author(s):  
Jacqueline Giovanna De Roza ◽  
David Wei Liang Ng ◽  
Blessy Koottappal Mathew ◽  
Teena Jose ◽  
Ling Jia Goh ◽  
...  

Abstract BackgroundFalls in older adults is a common problem worldwide. Fear of falling (FoF) is a consequence of falls which has far-reaching implications including activity restriction, functional decline and reduced quality of life. This study aimed to determine the factors associated with FoF in a segment of Singapore’s community-dwelling older adults. MethodsThis descriptive cross-sectional study recruited a convenience sample of adults aged 65 and above from 4 primary care clinics from September 2020 to March 2021. Data were collected on demographic factors and clinical factors including history of falls and frailty as determined by the Clinical Frailty Scale (CFS). FoF was measured using the Short Falls Efficacy Scale–International (Short FES-I), cut-off score of 14 and above indicated high FoF. Logistic regression was used to determine predictors of high FoF.ResultsOut of 360 older adults, 78.1% were Chinese and 59.7% females. The mean age was 78.3 years and 76 (21.1%) had a history of falls in the past six months. Almost half (43.1%) were mildly to moderately frail and most (80.6%) had three or more chronic conditions. The mean FoF score was 15.5 (SD 5.97) and 60.8% reported high FoF. Logistic regression found that Malay ethnicity (OR = 5.81, 95% CI 1.77 – 19.13), use of walking aids (OR = 3.67, 95% CI = 1.54 – 8.77) and increasing frailty were significant predictors for high FoF. The odds of high FoF were significantly higher in pre frail older adults (OR = 6.87, 95% CI = 2.66 – 17.37), mildly frail older adults (OR =18.58, 95% CI = 4.88 – 70.34) and moderately frail older adults (OR = 144.78, 95% CI = 13.86 – 1512.60).ConclusionsFoF is a prevalent and compelling issue in community-dwelling older adults, particularly those with frailty. The demographic and clinical factors identified in this study will be helpful to develop targeted and tailored interventions for FoF.


2019 ◽  
Vol 38 (2) ◽  
pp. 877-882 ◽  
Author(s):  
Maribel Ramírez Torres ◽  
Roxana E. Ruiz Valenzuela ◽  
Julián Esparza-Romero ◽  
Miriam T. López Teros ◽  
Heliodoro Alemán-Mateo

2012 ◽  
pp. 1-6
Author(s):  
A. BARUSCH ◽  
D.L. WATERS

Background:Social isolation is a significant problem for frail older adults and the determinants ofsocial engagement are poorly understood. Objectives:This study explored the social engagement of frail eldersto identify personal attributes associated with social engagement. Design, Setting and Participants:A cross-sectional sample of seventy-three people receiving home-based care in one town on the South Island of NewZealand (mean age 82 (7.2) yrs, n=51 Females, 21 Males). Measurements:Face-to-face semi-structuredinterviews and questionnaires. Functional independence was measured using Nottingham Extended Activities ofDaily Living (EADL), self-efficacy by General Self Efficacy Scale, and 2 open-ended questions were piloted onsocial activities and helping others. Results:Regression models identified two statistically associatedcomponents of social engagement: social activities and civic involvement. Contributions to families andcommunity organizations and exercise were important social activities. Personal attributes included perceivedfunctional independence and self-efficacy. Conclusions:In frail older adults, a measurement of socialengagement should address activities older adults identify as important, including exercise. Independence, self -efficacy, and social engagement may interact in reinforcing cycles of empowerment and could play a role indeveloping interventions to retain and maintain function in frail older adults.


Author(s):  
Bokun Kim ◽  
Hyuntae Park ◽  
Gwonmin Kim ◽  
Tomonori Isobe ◽  
Takeji Sakae ◽  
...  

This cross-sectional pilot study aimed to assess the relationships of fat and muscle mass with chronic kidney disease (CKD) in older adults. Serum creatinine concentration was used to measure estimated glomerular filtration rate (mL/min/1.73 m2) in the 236 subjects, who were allocated to three groups: a normal (≥60.0), a mild CKD (45.0–59.9), and a moderate to severe CKD (<45.0) group. The Jonckheere-Terpstra test and multivariate logistic regression were employed to assess body composition trends and the relationships of % fat mass (FM) or % muscle mass index (MMI) with moderate-to-severe CKD. Body weight, fat-free mass, MMI, and %MMI tended to decrease with an increase in the severity of CKD, but the opposite trend was identified for %FM. No relationship with BMI was identified. The participants in the middle-high and highest quartile for %FM were 6.55 and 14.31 times more likely to have moderate to severe CKD. Conversely, the participants in the highest quartile for %MMI were 0.07 times less likely to have moderate to severe CKD. Thus, high fat and low muscle mass may be more strongly associated with CKD than obesity per se.


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