scholarly journals Association Between Patient Activation and Medication Adherence in Patients With Stroke: A Cross-Sectional Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Weijing Sui ◽  
Li-hong Wan
Keyword(s):  
Regression Analysis ◽  
Medication Adherence ◽  
Influencing Factor ◽  
Linear Regression Analysis ◽  
Univariate Analysis ◽  
Patient Activation ◽  
Multiple Linear Regression Analysis ◽  
Improve Medication Adherence ◽  
Cross Sectional ◽  
Low Level

Background: Medication adherence is key to secondary prevention in patients with stroke. Poor medication adherence can lead to recurrence, disability, or even death in stroke survivors. Patient activation is associated with increased healthy behaviors and improved clinical outcomes in many chronic diseases. However, the association between patient activation and medication adherence in patients with stroke remains unclear.Objective: The study aimed to explore the influence of patient activation on the medication adherence of patients with stroke and to analyze the reasons for medication nonadherence.Materials and Methods: A cross-sectional design with convenience sampling was used in this study. A total of 119 patients with stroke were recruited from a tertiary hospital in Guangzhou. A social-demographic and clinical data form, a self-developed medication adherence questionnaire, and the 13-item Patient Activation Measure (PAM-13) were used. Univariate analysis and multiple linear regression analysis with dummy variables were conducted to investigate the associations between medication adherence and patient activation. Data were analyzed with IBM® SPSS® version 25.0.Results: The mean PAM-13 score in patients with stroke was 51.56 ± 12.58. A low level of patient activation was reported by up to 66.4% of the patients. The self-reported medication adherence questionnaire score was 5.59 ± 1.52. A low level of medication adherence was reported by up to 59.7% of the patients, while a moderate level was reported by 34.4%, and a high level was reported by only 5.9%. In the multiple stepwise regression analysis, patient activation was found to be an independent influencing factor of medication adherence in patients with stroke (p < 0.05).Conclusion: Medication adherence was poor in patients in Guangzhou, China, following an ischemic stroke. Patient activation as the independent influencing factor identified in this study will support healthcare givers to develop the tailored intervention to improve medication adherence among patients with stroke in China.

scholarly journals Oxidative stress and gut-derived lipopolysaccharides in children affected by Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections.

2020 ◽  
Author(s):  
Lorenzo Loffredo ◽  
Alberto Spalice ◽  
Francesca Salvatori ◽  
De Castro Giovanna ◽  
Cristiana Alessia Guido ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Linear Regression ◽  
Linear Regression Analysis ◽  
Prostaglandin F2α ◽  
Neuropsychiatric Disorders ◽  
Serum Levels ◽  
Multiple Linear Regression Analysis ◽  
Tic Disorders ◽  
Streptococcal Infections ◽  
Cross Sectional

Abstract Background: pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections syndrome (PANDAS) identifies patients with acute onset of obsessive-compulsive and tic disorders. The objective of this study was to assess NOX2 levels, as well as serum 8-iso-prostaglandin F2α (iso-PGF2α) and lipopolysaccharide (LPS) derived from Gram-negative bacteria in the gut of patients with PANDAS. Methods: a cross sectional study was performed to compare serum levels of soluble NOX2-dp (sNOX-2-dp), isoprostanes and LPS in 60 consecutive subjects, including 30 children affected by PANDAS and 30 controls (CT) matched for age and gender. Serum zonulin was used to assess gut permeability. Results: compared with CT, PANDAS children had higher values of sNOX-2-dp, 8-iso-PGF2-alpha and LPS. Simple linear regression analysis showed that sNOX2-dp was significantly correlated with serum LPS (Rs=0.359; p=0.005), zonulin (Rs=0.444; p<0.001) and iso-PGF2α (Rs=0.704; p<0.001). LPS significantly correlated with serum zonulin (Rs=0.610; p<0.001), and iso-PGF2α (Rs=0.591; p=0.001). A multiple linear regression analysis was performed to define the independent predictors of sNOX-2-dp. Isoprostanes and zonulin emerged as the only independent predictive variables associated with sNOX2-dp (R2=68%). Conclusion: this study provides evidences that children affected by PANDAS have high circulating levels of sNOX2-dp, isoprostanes and of LPS that could be potentially implicated in the process of neuroinflammation.

scholarly journals Analysis of the chemerin and resistin adipokines in children and adolescents

2020 ◽  
Vol 66 (3) ◽  
pp. 300-306
Author(s):  
Vanessa S. Fontes ◽  
Kácia Mateus ◽  
Michele P. Netto ◽  
Renata M. S. Oliveira ◽  
George L. L. Machado-Coelho ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Regression Analysis ◽  
Linear Regression ◽  
Children And Adolescents ◽  
Blood Pressure Measurement ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Excess Weight ◽  
Cross Sectional ◽  
Significance Level

SUMMARY OBJECTIVES To compare the serum concentrations of adipokines resistin and chemerin in children and adolescents with eutrophic and overweight and to evaluate their relationship with anthropometric, biochemical, and blood pressure variables. METHODS a cross-sectional epidemiological study was conducted with 234 students enrolled in public elementary schools in the city of Juiz de Fora / MG. Anthropometric evaluation, biochemistry, and blood pressure measurement were performed. Statistical analyzes included the Student-t or Mann-Whitney tests, Pearson or Spearman correlation, used according to the distribution of the variables, and linear regression analysis, by means of the evaluation of the effect of the independent variables on the serum levels of chemerin and resistin, adjusted for age and sex. For the data analysis, SPSS® software version 21.0 and STATA® version 10.1 were used, assuming a significance level of 5%. RESULTS the concentrations of chemerin were higher in eutrophic individuals than in those with excess weight (p> 0.05). In contrast, levels of resistin were higher in the young with excess weight than in the eutrophic ones (p <0.05). In the multiple linear regression analysis, the levels of chemerin were associated with the values of resistin, systolic, and diastolic blood pressure. Resistance levels maintained association only with BMI and chemerin values. CONCLUSION the adipokines analyzed presented a distinct profile in the groups of children and adolescents with eutrophic and overweight.

scholarly journals Oxidative stress and gut-derived lipopolysaccharides in children affected by Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections.

2020 ◽  
Author(s):  
Lorenzo Loffredo ◽  
Alberto Spalice ◽  
Francesca Salvatori ◽  
De Castro Giovanna ◽  
Cristiana Alessia Guido ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Linear Regression ◽  
Linear Regression Analysis ◽  
Prostaglandin F2α ◽  
Neuropsychiatric Disorders ◽  
Serum Levels ◽  
Multiple Linear Regression Analysis ◽  
Tic Disorders ◽  
Streptococcal Infections ◽  
Cross Sectional

Abstract Background: pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections syndrome (PANDAS) identifies patients with acute onset of obsessive-compulsive and tic disorders. The objective of this study was to evaluate serum NOX2 levels, as well as 8-iso-prostaglandin F2α (iso-PGF2α) and lipopolysaccharide (LPS) of PANDAS patients. Methods: a cross sectional study was performed to compare serum levels of soluble NOX2-dp (sNOX-2-dp), isoprostanes and LPS in 60 consecutive subjects, including 30 children affected by PANDAS and 30 controls (CT) matched for age and gender. Serum zonulin was used as intestinal permeability assay. Results: compared with CT, PANDAS children had increased values of sNOX-2-dp, 8-iso-PGF2-alpha and LPS. Simple linear regression analysis showed that sNOX2-dp was significantly correlated with serum LPS (Rs=0.359; p=0.005), zonulin (Rs=0.444; p<0.001) and iso-PGF2α (Rs=0.704; p<0.001). Serum LPS significantly correlated with zonulin (Rs=0.610; p<0.001), and iso-PGF2α (Rs=0.591; p=0.001). Finally, a multiple linear regression analysis was performed to define the independent predictors of sNOX-2-dp. Serum isoprostanes and zonulin resulted as the only independent predictive variables associated with sNOX2-dp (R2=68%). Conclusion: this study shows that children affected by PANDAS have high circulating levels of sNOX2-dp, isoprostanes and of LPS that could be potentially implicated in the process of neuroinflammation.

scholarly journals GAMBARAN SUPERVISI, IKLIM KERJA SERTA KEPUASAN KERJA KARYAWAN PT. TRIBUANA REKAYASA BANDUNG

2018 ◽  
Vol 3 (1) ◽  
pp. 81-86
Author(s):  
Devi Robissalami ◽  
Sumiyati Sumiyati ◽  
Eded Tarmedi
Keyword(s):  
Regression Analysis ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Positive Influence ◽  
Cross Sectional ◽  
Employee Job Satisfaction ◽  
Analysis Technique ◽  
The Difference ◽  
Cross Sectional Design ◽  
The Impact

Purpose - The purpose of this study is to determine the effect of supervision and working climate on employee job satisfactionDesign / methodology / approach - This research was conducted in less than 1 year period, the research design is cross-sectional design. The method used is exolanatory survey, and population 67 employees. The analysis technique used is descriptive, the questionnaire is used as a research instrument to collect data from respondents.Findings - based on the results of the study using multiple linear regression analysis, the result that there is a positive influence of supervision and work climate on employee job satisfaction.Originality / value - this study provides a basis for find out the impact of supervision and working climate on employee job satisfaction. The difference of this study with previous research is on the objects, variables, theories and the references.

MO595FREQUENCY OF INTAKE OF DIETARY FIBER SOURCES NOT ASSOCIATED WITH HYPERKALEMIA IN HEMODIALYS PATIENTS IN A MULTICENTER STUDY

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Rafaela G Dos Santos ◽  
Juliana Malinovski ◽  
Natália Scatone ◽  
Jorgiane De Oliveira ◽  
Andrea Sczip ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Dietary Fiber ◽  
Serum Potassium ◽  
Fruits And Vegetables ◽  
Linear Regression Analysis ◽  
Univariate Analysis ◽  
Laboratory Data ◽  
Food Groups ◽  
Analysis Model ◽  
Cross Sectional

Abstract Background and Aims Patients undergoing hemodialysis (HD) treatment usually have a low intake of food groups rich in dietary fiber to avoid hyperkalemia. However, dietary potassium is not associated with serum potassium or hyperkalemia in recent studies, and higher intake of fiber food groups such as fruits and vegetables is associated with lower mortality and other complications in HD populations. This multicenter cross-sectional study aimed to investigate the frequency of intake of dietary fiber sources, its determinants, and the relationship with hyperkalemia in HD patients. Method Prevalent HD patients from four dialysis clinics in Southern Brazil were invited to participate (at least 80% of eligible patients from each clinic). Patients were interviewed by the researchers and answered a food frequency questionnaire (FFQ) with the main dietary fiber sources (fruits, vegetables, legumes, whole grains cereals and seeds) with seven frequency possibilities (from never to more than twice a day). To estimate the weekly frequency of intake, answers were transformed into a score. Every score point corresponded to one time per week (ex.: score 7 = seven times per week). The sum of the five scores was calculated to determine the total score. Demographical and laboratory data were obtained from medical records. Univariate analysis was used to assess total score associations, and the variables with P&lt;0.20 were included in the regression analysis model. Results 305 HD patients were included (male: 51%; age: 52.2 ± 14.7 years old; HD vintage: 46 (19 – 82) months; hyperkalemia: 29%). Median (interquartile) FFQ scores were: fruits: 6 (2-14); vegetables: 6 (3-10); legumes: 3 (1-7); whole-grain: 0 (0-1) and seeds: 0 (0-0). Total score was 19 (14-28) and correlated with age (r=0.15; P=0.01), HD vintage (r=-0.22; P=&lt;0.001) and body mass index (BMI) (r=0.15; P=0.007). Patients with diabetes had a higher total score (22 (15-31) versus 18 (13-27) P=0.03). Only the vegetables score correlated with serum potassium (r=0.17; P=0.03) and no difference was found between dietary fiber food groups scores and total score with hyperkalemia. The linear regression analysis model also included gender and education (years at school) (all with P&lt;0.20 in the univariate analysis). The independent predictors of dietary fiber total score were age (OR=0.1 (95%IC 0.01-0.20);P=0.04), HD vintage (month) (OR=-0.03 (95%IC -0.06 - -0.01);P=0.02) and years at school (OR=0.27 (95%IC 0.85-0.46);P=0.005). Conclusion The usual frequency of intake of fiber sources was low, and its independent determinants were age, HD vintage and education. The lack of association with hyperkalemia suggests that other dietary sources and clinical factors should be considered to manage hyperkalemia in this population.

scholarly journals Biomarkers of Hemodynamic Stress and Aortic Stiffness after STEMI: A Cross-Sectional Analysis

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Sebastian Johannes Reinstadler ◽  
Hans-Josef Feistritzer ◽  
Gert Klug ◽  
Agnes Mayr ◽  
Luc Huybrechts ◽  
...  
Keyword(s):  
Natriuretic Peptide ◽  
Aortic Stiffness ◽  
Linear Regression Analysis ◽  
Univariate Analysis ◽  
Area Under The Curve ◽  
Multiple Linear Regression Analysis ◽  
Cross Sectional ◽  
Chronic Stage ◽  
St Segment Elevation ◽  
Hemodynamic Stress

Aim. Increased aortic stiffness might adversely affect cardiac structure, function, and perfusion. Release of biomarkers of hemodynamic stress is thought to be enhanced by these alterations. We aimed to evaluate the association between biomarkers of hemodynamic stress and aortic stiffness assessed at a chronic stage after ST-segment elevation myocardial infarction (STEMI).Methods. Fifty-four patients four months after STEMI were enrolled in this cross-sectional, single-center study. N-terminal pro–B-type natriuretic peptide (NT-proBNP), mid-regional pro–A-type natriuretic peptide (MR-proANP), and mid-regional proadrenomedullin (MR-proADM) levels were measured by established assays. Aortic stiffness was assessed by the measurement of pulse wave velocity using phase-contrast cardiovascular magnetic resonance.Results. NT-proBNP, MR-proANP, and MR-proADM concentrations were all correlated with aortic stiffness in univariate analysis (r=0.378,r=0.425, andr=0.532; allP<0.005, resp.). In multiple linear regression analysis, NT-proBNP (β=0.316,P=0.005) and MR-proADM (β=0.284,P<0.020) levels were associated with increased aortic stiffness independently of age, blood pressure, and renal function. NT-proBNP was the strongest predictor for high aortic stiffness (area under the curve: 0.82, 95% CI 0.67–0.96).Conclusion. At a chronic stage after STEMI, concentrations of biomarkers for hemodynamic stress, especially NT-proBNP, are positively correlated with aortic stiffness. These biomarkers might also be useful as predictors of high aortic stiffness after STEMI.

scholarly journals Fear of future workplace violence and its influencing factors among nurses in Shandong, China: a cross-sectional study

BMC Nursing ◽  
2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Chang Fu ◽  
Yaru Ren ◽  
Guowen Wang ◽  
Xiuxin Shi ◽  
Fenglin Cao
Keyword(s):  
Social Support ◽  
Regression Analysis ◽  
Influencing Factors ◽  
Workplace Violence ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
High Level

Abstract Background Fear of workplace violence has become a critical issue worldwide, which can lead to burnout, low levels of job satisfaction, and turnover. However, to date, little attention has been directed toward fear of workplace violence among nurses. Accordingly, this study investigated the level of fear of future workplace violence and its influencing factors among nurses in Shandong, China. Methods A cross-sectional study was conducted from July 30 through September 30, 2020 in Shandong Province, China. A total of 1898 nurses were enrolled from 12 tertiary hospitals. Fear of future workplace violence was measured using the Fear of Future Violence at Work scale. Demographic information, employment characteristics, social support, and experience of workplace violence were assessed. Multiple linear regression analysis was used to explore the influencing factors of fear of future workplace violence. Results The average score of fear of future violence at work was 67.43 ± 17.20 among nurses. Multiple linear regression analysis showed that higher fear of future violence at work scores were reported among nurses who were female (B = 7.10, p < 0.001), married (B = 3.50, p = 0.028), with a monthly income ≥5000 Chinese yuan (CNY) (B = 3.14, p = 0.007), working in the department of internal medicine (B = 2.90, p = 0.032), surgery (B = 5.03, p < 0.001), pediatrics (B = 5.38, p = 0.003), or emergency department (B = 4.50, p = 0.010), working as a contract employee (B = 2.41, p = 0.042), or who had experienced workplace violence (B = 7.02, p < 0.001). Lower fear of future violence at work scores were found among nurses who took vacations (1–14 days: B = − 2.52, p = 0.047; ≥15 days: B = − 3.69, p = 0.007) and had a high-level of social support (B = − 2.03, p = 0.020). Conclusions There was a high level of fear of future workplace violence among nurses in Shandong, China. This should be considered an important issue by hospital administrators and government officials. Effective interventions need to be enacted to address the influencing factors of fear of future workplace violence.

scholarly journals Association between Visceral or Subcutaneous Fat Accumulation and B-Type Natriuretic Peptide among Japanese Subjects: A Cross-Sectional Study

2021 ◽  
Vol 10 (6) ◽  
pp. 1315
Author(s):  
Yoshinori Hayashi ◽  
Hirohide Yokokawa ◽  
Hiroshi Fukuda ◽  
Mizue Saita ◽  
Taiju Miyagami ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Linear Regression ◽  
Multiple Linear Regression ◽  
Natriuretic Peptide ◽  
Linear Regression Analysis ◽  
Subcutaneous Fat ◽  
Multiple Linear Regression Analysis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Background: Some previous studies have shown reduced levels of plasma B-type natriuretic peptide (BNP) in individuals with obesity. We aimed to estimate the relationship between BNP and abdominal fat distribution, adjusted for confounding factors. Methods: This cross-sectional study included 1806 Japanese individuals (981 men and 825 women) who underwent a medical health check-up. Analyzed data included age, sex, visceral fat area (VFA), and subcutaneous fat area (SFA) as obtained from computed tomography, blood pressure, and blood test results including BNP. Multiple linear regression analysis was used to examine the association between BNP, VFA, and SFA after adjusting for age, sex, comorbidities, and body mass index. Results: In the models analyzed separately for VFA and SFA, BNP correlated independently with VFA in multiple linear regression analysis among all subjects and in both men and women, while SFA correlated inversely with BNP in all subjects and women but not in men. In the model that included both VFA and SFA, BNP correlated independently with VFA, but SFA and BNP were not correlated in any models. Conclusion: Higher VFA showed an independent, significant association with lower BNP. In addition, the inverse correlation with BNP was stronger for VFA than for SFA.

scholarly journals The Combined Effects of Patient Activation and Relational Aspects on the Quality of Life in Atrial Fibrillation Patients

2021 ◽  
Vol 12 ◽  
Author(s):  
Jie Wang ◽  
Qin Wang ◽  
Zhipeng Bao ◽  
Yuanyuan Peng ◽  
Shenxinyu Liu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Atrial Fibrillation ◽  
Regression Analysis ◽  
Linear Regression ◽  
Multiple Linear Regression ◽  
Linear Regression Analysis ◽  
Patient Activation ◽  
Multiple Linear Regression Analysis ◽  
Daily Activities

Objective: This study aims to explore the influence of patient activation (PA) and relational aspects on the quality of life (QoL) in patients with Atrial Fibrillation (AF) for developing measures to improve PA and QoL.Methods: A cross-sectional study was undertaken in 2021 among 190 AF patients in Nanjing, China. Research instruments included a self-designed social-demographic characteristics scale, the Patient Activation Measure (PAM), the Atrial Fibrillation Effect on Quality of Life (AFEQT). The data analysis was performed using IBM SPSS 25.0. Spearman correlation analysis, multiple linear regression analysis, and Wilcoxon rank-sum tests were used to assess the association accordingly.Results: The average AFEQT score for the 190 AF patients was 69.32 ± 14.52. The distribution of activation Levels 1, 2, 3, and 4, were where 4.7, 34.2, 47.4, and 13.7%, respectively. The multiple linear regression analysis revealed that patient activation, work status, and cardiac rehabilitation of AF patients predicted AF-related QoL (β = 0.270, −0.205, and 0.183, respectively; all P &lt; 0.05). The influences of PA level on subdimensions of AF-related QoL were as follows: symptoms, daily activities and treatment concern.Conclusion: The level of QoL of patients with AF was moderate. Higher levels of patient activation in those with AF were associated with milder symptoms, more positive daily activities and fewer treatment concern. Based on our findings, we suggest that healthcare personnel should encourage AF patients to take active participation in cardiac rehabilitation, disease self-management and foster progression of PA level. Future research is warranted to develop tailor-made interventions aimed at the activation level.

scholarly journals The Association Between the Severity of the Mandibular Inferior Cortex Porosity and the Number of Remaining Teeth in Elderly Indonesian People

2019 ◽  
Author(s):  
Bramma Kiswanjaya ◽  
Hanna H Bachtiar-Iskandar
Keyword(s):  
Regression Analysis ◽  
Linear Regression ◽  
Multiple Linear Regression ◽  
Linear Regression Analysis ◽  
Secondary Data ◽  
Multiple Linear Regression Analysis ◽  
Nonparametric Tests ◽  
Cross Sectional ◽  
Panoramic Radiographs ◽  
The Relationship

Abstract Background The purpose of this study was to investigate the association between the severity of the mandibular inferior cortex (MIC) porosity and the number of remaining teeth in elderly Indonesian people.Materials and methods This cross-sectional study was conducted by measuring secondary data on panoramic digital examinations of patients aged 50 years and older. A total of 428 panoramic radiographs were measured from January 2017 to December 2018. The number of remaining teeth (including the third molars) was evaluated. Mandibular porosity was measured by using panoramic radiographs, according to the MIC classification: normal; mildly to moderately eroded; and severely eroded cortex.Statistical analysis used Data analysis was done using Mann-Whitney nonparametric tests to verify the relationship between the MIC classification and the number of remaining teeth. Multiple linear regression analysis was performed to investigate the relationship between confounding variables.Results A significant correlation was found between MIC classification and the number of remaining teeth on the Mann-Whitney test (P < 0.001). Multiple linear regression analysis showed that MIC classification was significantly associated with the value of the number of remaining teeth after controlling for gender and age (β = -0.37, R2 = 0.22, P < 0.001). Subjects with MIC class 3 were 7.14 times more likely to lose their teeth than subjects with MIC class 1 or class 2.Conclusions Our study demonstrated that there was an association between the severity of mandibular inferior cortex porosity and the number of remaining teeth in elderly Indonesian people.

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