scholarly journals Influence of Facial Morphology on Masticatory Function and Quality of Life in Elders Using Mandibular Overdentures: 3-Year Results

2021 ◽  
Vol 8 ◽  
Author(s):  
Anna Paula da Rosa Possebon ◽  
Alessandra Julie Schuster ◽  
Raissa Micaella Marcello-Machado ◽  
Ana Paula Pinto Martins ◽  
Luciana de Rezende Pinto ◽  
...  

Background: Facial types may interfere in the oral health-related quality of life (OHRQoL) and masticatory performance of implant-retained mandibular overdenture (IMO) wearers.Purpose: Investigate the medium-term changes in the masticatory function (MF) and OHRQoL parameters of IMO users, as a function of facial pattern, anteroposterior skeletal discrepancy, and sex.Methods: Forty IMO users, most of them Caucasian (90%) with average age of 69.17 years were classified according to their facial pattern and antero-posterior discrepancy prior to rehabilitation. MF was evaluated by the multiple sieves method to determine the average particle size (X50), heterogeneity (B) and masticatory efficiency (ME, calculated as the percentage of material retained in the 5.6 and 2.8 mm sieves), using Masticatory performance (MP) and swallowing threshold (ST) tests. OHRQoL was measured by applying the dental impact on daily life (DIDL) questionnaire. The data were analyzed by Wilcoxon-paired tests to analyze changes in MF parameters over time, and mixed-effect multilevel regression models were employed to verify differences between groups.Results: Significant changes were still observed in the 3rd year for the ST test with improvements in B for Mesofacial and in time for Dolichofacial individuals, while ME_2.8 deteriorated for Brachyfacial participants. B values of Class I and male individuals improved and brachyfacial individuals still presented worse homogenization (B) than Mesofacial participants in both masticatory tests. Class II and III participants still showed improvements in ME_5.6 and time compared to Class I despite increases in X50. Class II individuals needed less cycles than Class I in the 3rd year. Brachyfacial participants scored lower in the Appearance domain than Mesofacial ones in the 3rd year. Dolichofacial participants and Class III patients scored lower in the Oral Comfort domain than Mesofacial and Class I, respectively. In addition, age influenced the Pain, Oral Comfort and General Performance domains in the 3rd year.Conclusions: Differences in facial morphology continue to influence the MF and OHRQoL outcomes in the 3rd year, and age influenced some OHRQoL domains. Brachyfacial individuals continue to benefit least from rehabilitation with IMO according to masticatory parameters.

10.3823/2492 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Antonio Franklin Cordeiro Neto ◽  
Roberto Carlos Mourão Pinho ◽  
Raulison Vieira de Sousa ◽  
Bruna De Carvalho Farias Vajgel ◽  
Renata Cimões

Objective: The aim of this study was to evaluate whether the type of malocclusion affects the perception of quality and satisfaction with people's lives. Material and Methods: Three questionnaires were applied: the first one assessed the social and economic factors and the diagnosis of malocclusion through Angle´s classification, the second was the OHIP-14, and the third was the Satisfaction With Life Scale (SWLS). Results: This study involved 444 patients aged 18 to 72 years. According to the classification of malocclusion 48.65% was Class I, 22.75% was Class II division 1, 12.16% was Class II division 2 and Class III 16.44%. The malocclusion did not have negative impact on the level of satisfaction with life, but in all dimensions analyzed by OHIP-14, malocclusion had negative impact on quality of life and was statistically significant. The most severe malocclusions such as Class II and Class III represent a more negative impact when compared to Class I malocclusion. Moreover, for the dimensions assessed by the OHIP-14, physical pain and psychological discomfort were those who showed a greater negative impact on quality of life. Conclusions: Malocclusions do not interfere with the judgment of the level of satisfaction with life, but they produce a negative impact on quality of life.


2008 ◽  
Vol 78 (6) ◽  
pp. 977-982 ◽  
Author(s):  
Eduardo Bernabé ◽  
Aubrey Sheiham ◽  
Cesar Messias de Oliveira

Abstract Objective: To compare the prevalence, intensity, and extent of condition-specific oral impacts on quality of life attributed to malocclusion by Brazilian adolescents with normal occlusion and those with Angle Class I, II, and III malocclusion. Materials and Methods: Four groups of 55 adolescents were configured such that each group represented normal occlusion, as well as Angle Class I, II, and III malocclusion. No radiographs were taken. Adolescents aged 15 to 16 years were selected from those attending all secondary schools in Bauru (Sao Paulo, Brazil). The Oral Impacts on Daily Performances index was used to collect data on condition-specific impacts (CSIs) attributed to malocclusion. The prevalence, as well as the intensity and extent, of CSIs was compared among the four groups with the use of Chi-square and Kruskal-Wallis tests, respectively. Results: Groups were comparable according to sex, age, and socioeconomic status. The prevalence of CSI was significantly different between groups (P = .039). Class II and III malocclusion groups reported a higher prevalence of CSI than those with normal occlusion and Class I malocclusion. However, the intensity and extent of CSI were not significantly different between groups. Conclusions: The prevalence, but not the intensity and extent, of CSIs attributed to malocclusion differed among groups with different malocclusions. The present findings support the concept that malocclusion has physical, psychological, and social effects on quality of life.


2013 ◽  
Vol 58 (9) ◽  
pp. 1070-1077 ◽  
Author(s):  
Taís de Souza Barbosa ◽  
Maria Claudia de Morais Tureli ◽  
Marinês Nobre-dos-Santos ◽  
Regina Maria Puppin-Rontani ◽  
Maria Beatriz Duarte Gavião

Water ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2537 ◽  
Author(s):  
Mohamed K. Abdel-Fattah ◽  
Sameh Kotb Abd-Elmabod ◽  
Ali A. Aldosari ◽  
Ahmed S. Elrys ◽  
Elsayed Said Mohamed

Water scarcity and suitable irrigation water management in arid regions represent tangible challenges for sustainable agriculture. The current study aimed to apply multivariate analysis and to develop a simplified water quality assessment using principal component analysis (PCA) and the agglomerative hierarchical clustering (AHC) technique to assess the water quality of the Bahr Mouise canal in El-Sharkia Governorate, Egypt. The proposed methods depended on the monitored water chemical composition (e.g., pH, water electrical conductivity (ECiw), Ca2+, Mg2+, Na+, K+, HCO3−, Cl−, and SO42−) during 2019. Based on the supervised classification of satellite images (Landsat 8 Operational Land Imager (OLI)), the distinguished land use/land cover types around the Bahr Mouise canal were agriculture, urban, and water bodies, while the dominating land use was agriculture. The water quality of the Bahr Mouise canal was classified into two classes based on the application of the irrigation water quality index (IWQI), while the water quality was classified into three classes using the PCA and AHC methods. Temporal variations in water quality were investigated, where the water qualities in winter, autumn, and spring (January, February, March, April, November, and December) were classified as class I (no restrictions) based on IWQI application, and the water salinity, sodicity, and/or alkalinity did not represent limiting factors for irrigation water quality. On the other hand, in the summer season (May, June, July, August, and October), the irrigation water was classified as class II (low restrictions); therefore, irrigation processes during summer may lead to an increase in the alkalinity hazard. The PCA classifications were compared with the IWQI results; the PCA classifications had similar assessment results during the year, except in September, while the water quality was assigned to class II using the PCA method and class I by applying the IWQI. Furthermore, the normalized difference vegetation index (NDVI) around the Bahr Mouise canal over eight months and climatic data assisted in explaining the fluctuations in water quality during 2019 as a result of changing the crop season and agriculture management. Assessments of water quality help to conserve soil, reduce degradation risk, and support decision makers in order to obtain sustainable agriculture, especially under water irrigation scarcity and the limited agricultural land in such an arid region.


2020 ◽  
Vol 9 (8) ◽  
pp. 2676
Author(s):  
Shinya Kawamatsu ◽  
Ryota Jin ◽  
Shogo Araki ◽  
Hideki Yoshioka ◽  
Hiromi Sato ◽  
...  

The aim of this study was to elucidate the lifelong disease progression of chronic obstructive pulmonary disease (COPD) with biomarker changes and identify their influencing factors, by utilizing a new analysis method, Statistical Restoration of Fragmented Time-course (SReFT). Individual patient data (n = 1025) participating in the Study to Understand Mortality and MorbidITy (SUMMIT, NCT01313676), which was collected within the observational period of 4 years, were analyzed. The SReFT analysis suggested that scores of St. George’s Respiratory Questionnaire and COPD assessment test, representative scores of the health-related quality of life (HRQOL) questionnaire, increased consistently for 30 years of disease progression, which was not detected by conventional analysis with a linear mixed effect model. It was estimated by the SReFT analysis that normalized forced expiratory volume in one second for age, sex, and body size (%FEV1) reduced for the initial 10 years from the onset of the disease but thereafter remained constant. The analysis of HRQOL scores and lung functions suggested that smoking cessation slowed COPD progression by approximately half and that exacerbation accelerated it considerably. In conclusion, this retrospective study utilizing SReFT elucidated the progression of COPD over 30 years and associated quantitative changes in the HRQOL scores and lung functions.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
X Li ◽  
C H Y Leung ◽  
T Gao ◽  
V C H Chung ◽  
Yu FWP ◽  
...  

Abstract Introduction Despite good bracing compliance is crucial to prevent curve progression among braced AIS patients, only few interventions were suggested to improve bracing compliance. This study examined the effect of MBI on bracing compliance for AIS patients. Methods 116 eligible AIS patients were randomized and 86 participants were enrolled in intervention. Patients in the MBI group joint weekly sessions, which is an adapted version of mindfulness-based stress reduction (MBSR) program, for 8 weeks. Control group consisted of an 8-week PE intervention that is recommended according to the SOSORT 2011 guideline. The primary outcome is the 6-month post-intervention bracing compliance. The secondary outcomes include quality of life and psychosocial measurements. Primary analysis was ANCOVA with treatment as covariate. Trend analysis was conducted using Linear Mixed effect model. Results At the end of intervention, intention-to-treat analysis improved bracing compliance by1.24h/day and 0.08h/day for MBI and PE respectively. MBI group presented an increase in emotional regulation than baseline (ERQ-CCA) (1.92, p = 0.01), especially in Cognitive reappraisal sub-scale (1.00, p = 0.05). Bracing Specific Quality of Life (SRS-22) reduced significantly in both groups, but MBI group decreased less (MBI: -3.08, p = 0.00, PE -4.47, p = 0.00). Effect at six months for compliance progressed negatively but favoured MBI group (MBI: -1.16, p = 0.13, PE: -1.84, p = 0.06) although there was no significant difference between groups (p = 0.78). The Perception of stress (PSS) decreased significantly in PE group (-3,53, p = 0.01) rather than MBI (1.53, p = 0.22), however the between-group difference isn't significant (p = 0.62). Conclusions It is alarming that patients in both interventions group progressed with poorer compliance and worsen QoL. These progressions were less severe in the MBI group than in the PE group, but the differences did not reach statistical significant. Key messages Both groups decreased in compliance and QoL but MBI group reduced less. MBI wasn't more effective in improving participants’ compliance and other measurements.


Author(s):  
Melanie L R Wyld ◽  
Rachael L Morton ◽  
Leyla Aouad ◽  
Dianna Magliano ◽  
Kevan R Polkinghorne ◽  
...  

Abstract Background Quality-of-life is an essential outcome for clinical care. Both chronic kidney disease (CKD) and diabetes have been associated with poorer quality-of-life. The combined impact of having both diseases is less well understood. As diabetes is the most common cause of CKD, it is imperative that we deepen our understanding of their joint impact. Methods This was a prospective, longitudinal cohort study of community-based Australians aged ≥25 years who participated in the Australian Diabetes, Obesity and Lifestyle study. Quality-of-life was measured by physical component summary (PCS) and mental component summary sub-scores of the Short Form (36) Health Survey. Univariate and multivariate linear mixed effect regressions were performed. Results Of the 11 081 participants with quality-of-life measurements at baseline, 1112 had CKD, 1001 had diabetes and of these 271 had both. Of the 1112 with CKD 421 had Stage 1, 314 had Stage 2, 346 had Stage 3 and 31 had Stages 4/5. Adjusted linear mixed effect models showed baseline PCS was lower for those with both CKD and diabetes compared with either disease alone (P < 0.001). Longitudinal analysis demonstrated a more rapid decline in PCS in those with both diseases. Conclusions The combination of CKD and diabetes has a powerful adverse impact on quality-of-life, and participants with both diseases had significantly poorer quality-of-life than those with one condition.


2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Kathrin Reetz ◽  
◽  
Ralf-Dieter Hilgers ◽  
Susanne Isfort ◽  
Marc Dohmen ◽  
...  

Abstract Introduction Currently, no treatment that delays with the progression of Friedreich ataxia is available. In the majority of patients Friedreich ataxia is caused by homozygous pathological expansion of GAA repeats in the first intron of the FXN gene. Nicotinamide acts as a histone deacetylase inhibitor. Dose escalation studies have shown, that short term treatment with dosages of up to 4 g/day increase the expression of FXN mRNA and frataxin protein up to the levels of asymptomatic heterozygous gene carriers. The long-term effects and the effects on clinical endpoints, activities of daily living and quality of life are unknown. Methods The aim of the NICOFA study is to investigate the efficacy and safety of nicotinamide for the treatment of Friedreich ataxia over 24 months. An open-label dose adjustment wash-in period with nicotinamide (phase A: weeks 1–4) to the individually highest tolerated dose of 2–4 g nicotinamide/day will be followed by a 2 (nicotinamide group): 1 (placebo group) randomization (phase B: weeks 5–104). In the nicotinamide group, patients will continue with their individually highest tolerated dose between 2 and 4 g/d per os once daily and the placebo group patients will be receiving matching placebo. Safety assessments will consist of monitoring and recording of all adverse events and serious adverse events, regular monitoring of haematology, blood chemistry and urine values, regular measurement of vital signs and the performance of physical examinations including cardiological signs. The primary outcome is the change in the Scale for the Assessment and Rating of Ataxia (SARA) over time as compared with placebo in patients with Friedreich ataxia based on the linear mixed effect model (LMEM) model. Secondary endpoints are measures of quality of life, functional motor and cognitive measures, clinician’s and patient’s global impression-change scales as well as the up-regulation of the frataxin protein level, safety and survival/death. Perspective The NICOFA study represents one of the first attempts to assess the clinical efficacy of an epigenetic therapeutic intervention for this disease and will provide evidence of possible disease modifying effects of nicotinamide treatment in patients with Friedreich ataxia. Trial registration EudraCT-No.: 2017-002163-17, ClinicalTrials.govNCT03761511.


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