scholarly journals Bone Metastases of Glioblastoma: A Case Report and Review of the Literature

2021 ◽  
Vol 11 ◽  
Author(s):  
Wei Zhang ◽  
Yuan-yuan Cai ◽  
Xiao-li Wang ◽  
Xiao-xiao Wang ◽  
Yang Li ◽  
...  
Keyword(s):  
Bone Metastases ◽  
Local Relapse ◽  
Intercostal Nerve ◽  
Spinal Nerve ◽  
World Health ◽  
Extracranial Metastasis ◽  
Ct Guided ◽  
Health Organization ◽  
The Right ◽  
Primary Intracranial Tumor

BackgroundGlioblastoma (GBM) is the most common primary intracranial tumor and originates from the small pool of adult neural stem and progenitor cells (NSPCs). According to the World Health Organization (WHO) classification of brain tumors, gliomas are classified into grades I–IV, and GBM is defined as the highest grade (IV). GBM can be disseminated by cerebrospinal fluid (CSF), but extracranial metastasis is rare. Additionally, the pathway and mechanism involved remain unclear.Case PresentationWe report a rare case of left temporal lobe GBM with multiple bone metastases and soft tissue metastasis. This 49-year-old right-handed man who was diagnosed with GBM underwent surgery on May 9, 2017, followed by radiochemotherapy in June 2017. On August 13, 2019, local relapse was found. Then, the patient received a second surgery but not radiochemotherapy. In November 2019, the patient was reported to be suffering from low back pain for nearly 1 month. On December 6, 2019, magnetic resonance imaging (MRI) of the thoracolumbar vertebrae and abdominal computed tomography (CT) confirmed metastases on the ninth posterior rib on the right, the third anterior rib on the left, and the T7 and T10 vertebrae and their appendages. CT-guided rib space-occupying puncture biopsy was performed, and GBM was identified by pathology.ConclusionWe should pay attention to extracranial metastasis of GBM. Timely detection and early treatment improve overall quality of patients’ life. The extracranial metastasis in this patient may have occurred through the spinal nerve root or intercostal nerve. Further clinical observations are required to clarify the pathway and mechanism involved.

Implementing the Sphere Project’s standards for patient’s healthcare rights in the disaster zone: The experience of the Israeli field hospital in post-quake Nepal

2021 ◽  
Vol 16 (1) ◽  
pp. 59-66
Author(s):  
Deganit Kobliner-Friedman, RN, MPH ◽  
Ofer Merin, MD ◽  
Eran Mashiach, MD ◽  
Reuven Kedar, MD ◽  
Shai Schul, MHA ◽  
...  
Keyword(s):  
Disaster Response ◽  
Sexual Exploitation ◽  
World Health ◽  
Field Hospital ◽  
Medical Teams ◽  
Health Organization ◽  
The Individual ◽  
The Right ◽  
Israel Defense Forces ◽  
Privacy And Confidentiality

Emergency medical teams (EMTs) encounter chaos upon arriving at the scene of a disaster. Rescue efforts are utilitarian and focus on providing the technical aspects of medical care in order to save the most lives at the expense of the individual. This often neglects the basic healthcare rights of the patient. The Sphere Project was initiated to develop universal humanitarian standards for disaster response.The increase in the number of EMTs led the World Health Organization (WHO) to organize standards for disaster response. In 2016, the WHO certified the Israel Defense Forces Field Hospital (IDF-FH) as the first to be awarded the highest level of accreditation (EMT-3). This paper presents the IDF-FH’s efforts to protect the patient’s healthcare rights in a disaster zone based on the Sphere Principles.These core Sphere Principles include the right to professional medical treatment; the right to dignity, privacy, and confidentiality; the right for information in an understandable language; the right to informed consent; the obligation to maintain private medical records; the obligation to adhere to universal ethical standards, to respect culture and custom and to care for vulnerable populations; the right to protection from sexual exploitation and violence; and the right to continued treatment.

scholarly journals Lebanon Cities’ Public Spaces

2018 ◽  
Vol 3 (1) ◽  
pp. 119-152 ◽  
Author(s):  
Maryam Nazzal ◽  
Samer Chinder
Keyword(s):  
Green Space ◽  
Public Spaces ◽  
World Health ◽  
Right To The City ◽  
Social Connections ◽  
Land Prices ◽  
The Social ◽  
Health Organization ◽  
The Right ◽  
The City

In Lebanon, the social connections are undeniable and crucial. However, meeting places remain private such as houses, restaurants, malls, and beach resorts. This is mainly due to the shortage of public spaces in Lebanon resulting from lack of planning, regulations and awareness around the right to the city and the importance of public spaces. In main cities where land prices are so expensive, common practice has prioritized the use of land in real estate development, thus trumping other uses such as public and communal spaces.In the late 1990s, Lebanon saw the emergence of malls, which have arguably acted as alternatives to public spaces. Malls, with their wealth of food courts, restaurants, cinemas, and play areas, have become the new downtown for a portion of the Lebanese population. They are also considered safe, which is another important factor.In 2015, the percentage of green spaces in Lebanon has decreased to less than 13%. While the World Health Organization (WHO) recommends a minimum of 9m2 of green space per capita (UN-HABITAT, 2016), Beirut has only 0.8m2.

scholarly journals THE HUMAN RIGHT TO HEALTH: A RETROSPECTIVE ANALYSIS AFTER 70 YEARS OF INTERNATIONAL RECOGNITION

2018 ◽  
pp. 24-42
Author(s):  
MARÍA DALLI
Keyword(s):  
Human Rights ◽  
Right To Health ◽  
World Health ◽  
Health Coverage ◽  
Human Right ◽  
The Sustainable Development ◽  
Cultural Rights ◽  
Health Organization ◽  
The Individual ◽  
The Right

In 1948, the General Assembly of the United Nations adopted the first international text recognising universal human rights for all; the Universal Declaration of Human Rights. Article 25 recognises the right to an adequate standard of living, which includes the right to health and medical care. On the occasion of the 70th anniversary of the Declaration, this article presents an overview of the main developments that have been made towards understanding the content and implications of the right to health, as well as an analysis of some specific advancements that aim to facilitate the enforcement thereof. These include: a) the implication of private entities as responsible for right to health obligations; b) the Universal Health Coverage goal, proposed by the World Health Organization and included as one of the Sustainable Development Goals; and c) the individual complaints mechanism introduced by the Optional Protocol to the International Covenant on Economic, Social and Cultural Rights (adopted on the 10th December 2008, 60 years after the UDHR).

scholarly journals What Is the Role of Interleukins in Breast Cancer Bone Metastases? A Systematic Review of Preclinical and Clinical Evidence

Cancers ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 2018 ◽  
Author(s):  
Francesca Salamanna ◽  
Veronica Borsari ◽  
Deyanira Contartese ◽  
Viviana Costa ◽  
Gianluca Giavaresi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Trials ◽  
Bone Metastases ◽  
Metastatic Breast ◽  
World Health ◽  
Therapeutic Effects ◽  
Preclinical Studies ◽  
Functional Roles ◽  
Novel Strategy ◽  
Health Organization

Breast cancer cells produce stimulators of bone resorption known as interleukins (ILs). However, data on the functional roles of ILs in the homing of metastatic breast cancer to bone are still fragmented. A systematic search was carried out in three databases (PubMed, Scopus, Web of Science Core Collection) to identify preclinical reports, and in three clinical registers (ClinicalTrials.gov, World Health Organization (WHO) International Clinical Trials Registry Platform, European Union (EU) Clinical Trials Register) to identify clinical trials, from 2008 to 2019. Sixty-seven preclinical studies and 11 clinical trials were recognized as eligible. Although preclinical studies identified specific key ILs which promote breast cancer bone metastases, which have pro-metastatic effects (e.g., IL-6, IL-8, IL-1β, IL-11), and whose inhibition also shows potential preclinical therapeutic effects, the clinical trials focused principally on ILs (IL-2 and IL-12), which have an anti-metastatic effect and a potential to generate a localized and systemic antitumor response. However, these clinical trials are yet to post any results or conclusions. This inconsistency indicates that further studies are necessary to further develop the understanding of cellular and molecular relations, as well as signaling pathways, both up- and downstream of ILs, which could represent a novel strategy to treat tumors that are resistant to standard care therapies for patients affected by breast cancer bone disease.

Right diagnosis, right treatment: SAFER PRACTICES

2019 ◽  
Vol 1 (7) ◽  
pp. 356-360 ◽  
Author(s):  
Paul Silverston
Keyword(s):  
Clinical Practice ◽  
Health Professionals ◽  
Diagnostic Errors ◽  
Integrated Approach ◽  
Diagnostic Error ◽  
World Health ◽  
Formal Training ◽  
The World ◽  
Health Organization ◽  
The Right

Choosing the right treatment for the patient requires that the right diagnosis is made first. In primary and ambulatory care, however, diagnostic errors are both common and commonly preventable. The World Health Organization has recommended that all health professionals should receive formal training in the principles of diagnostic reasoning and the causes of diagnostic error, and that strategies and interventions to reduce the risk of diagnostic error should be used in clinical practice. This article describes a mnemonic checklist, SAFER PRACTICES, which can be used in an integrated approach to the prevention and detection of diagnostic errors that starts in the classroom and continues through to the consulting room.

scholarly journals Everything counts in sending the right message: science-based messaging implications from the 2020 WHO guidelines on physical activity and sedentary behaviour

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Michelle L. Segar ◽  
Marta M. Marques ◽  
Antonio L. Palmeira ◽  
Anthony D. Okely
Keyword(s):  
Physical Activity ◽  
Sedentary Behaviour ◽  
Psychological Needs ◽  
World Health ◽  
Behavioural Science ◽  
Aerobic Activity ◽  
New Guidelines ◽  
Health Organization ◽  
The Right ◽  
Country Specific

Abstract The World Health Organization (WHO) released the 2020 global guidelines on physical activity and sedentary behaviour. The new guidelines contain a significant change from the 2010 guidelines on physical activity for adults and older adults that has important implications for next-generation physical activity messaging: The removal of the need for aerobic activity to occur in bouts of at least 10 min duration. This change in the guidelines provides an opportunity to communicate in new ways that align with behavioural science, permitting physical activity communicators and promoters to better support people’s psychological needs, motivation, and ability to fit healthy levels of physical activity into their lives. The frames and messages we use to communicate about the guidelines matter because they influence whether activity is perceived as relevant, meaningful, and feasible – or not. When developing new physical activity communications there are some overarching principles, based on behavioural science, to keep in mind. Using established theory, this commentary aims to support the creation of more strategic frames and messages for increasing the value and integration of physical activity into daily living. Country-specific physical activity campaigns using these ideas will be discussed.

scholarly journals Lipomatous tumours in adrenal gland: WHO updates and clinical implications

2017 ◽  
Vol 24 (3) ◽  
pp. R65-R79 ◽  
Author(s):  
Alfred King-yin Lam
Keyword(s):  
Adrenal Gland ◽  
Age Distribution ◽  
World Health ◽  
Adrenal Myelolipoma ◽  
Adrenal Tumours ◽  
Endocrine Organs ◽  
Lipomatous Tumour ◽  
Health Organization ◽  
The Right

Adrenal lipomatous tumour is a group of adrenal tumours with a significant component of adipose tissue. According to the current World Health Organization (WHO) classification of tumours of endocrine organs, adrenal myelolipoma is the only entity amongst the group of tumours being described. In the literature, other more recently documented adrenal lipomatous tumours included 24 lipomas, 32 teratomas and 16 angiomyolipomas. Rare fatty tumours of the adrenal gland comprised liposarcoma, hibernoma, adrenocortical tumours with fat component and rare adrenal tumours with fat component. Myelolipoma comprises approximately 3% of primary adrenal tumour. It is noted more commonly in females and in the right adrenal gland. Approximately 40 bilateral myelolipomas were reported. The tumour is most frequently recorded in patients between fifth and seventh decades of life. Adrenal lipomas are often seen in males and in the right adrenal gland. They were commonly noted in patients in the sixth decade of life. The diagnosis could only be possible on examination of the surgically removed specimen. Adrenal teratomas were more common in females and with a bimodal age distribution. Slightly over 60% of the patients with adrenal teratoma are symptomatic. Adrenal angiomyolipomas were often symptomatic, more common in females and in the fifth decades of life. To conclude, adrenal lipomatous tumour is uncommon. They are often benign and non-functional. It is important to recognize the features of this group of lipomatous tumours in the adrenal gland as they are being detected on increasing incidence as a result of the wide-spread use of modern imaging modalities.

scholarly journals COVID-19 Knowledge Resource Categorization and Tracking: A Conceptual Framework (Preprint)

2021 ◽  
Author(s):  
Muhammad Afzal ◽  
Maqbool Hussain ◽  
Jamil Hussain ◽  
Sungyoung Lee
Keyword(s):  
Conceptual Framework ◽  
Level Structure ◽  
Global Scale ◽  
Information Resources ◽  
World Health ◽  
Infrastructure Development ◽  
Knowledge Resources ◽  
Health Organization ◽  
The Right ◽  
Resource Categorization

BACKGROUND Declaring the COVID-19 disease a global pandemic by the World Health Organization (WHO), it gained momentum as every day passed, and private and government sectors of different countries pushed funding towards research in various capacities. A great portion of efforts is devoted to information technology and service infrastructure development, including research to develop intelligent models and techniques for alerts, monitoring, early diagnosis, prevention, and other relevant services. As a result, tons of information resource have been created in the global space and are available for use. However, there is lack of a defined structure to organize these resources into categories or classes based on the nature as well the origin of data. OBJECTIVE This study aims to organize COVID-19 information resources into a well-defined structure to facilitate easy identification of a resource, tracing information workflows, and a guide for contextual dashboards design and development. METHODS A sequence of action research was performed that involve a review of COVID-19 efforts and initiatives on a global scale during the year 2020. Data is collected according to a defined structure of primary, secondary, and tertiary categories. Various descriptive statistical analysis techniques were employed to get insights of the data to help in developing a conceptual framework underlining the organization of resources and interactions among different resources. RESULTS In this paper, we present a three-level structure of resource categorization that provides a gateway to access the global initiatives with enriched metadata, assists users in tracing the workflow of tertiary, secondary, and primary resources with relationships among various fragments of information. The results comprise mapping initiatives at the tertiary level to secondary and then to the primary level to reach the firsthand resource of data, research, and trials. CONCLUSIONS Adopting the proposed three-level structure enables a consistent organization and management of existing COVID-19 knowledge resources and provides a roadmap for classifying the futuristic resources. This study is one of the earliest studies to introduce an organized structure and demonstrate the placement of COVID-19 resources at the right place. By implementing the proposed framework according to the stated guidelines, this study facilitates the development of applications such as interactive dashboards to facilitate the contextual identification and tracking of interdependent COVID-19 information resources.

scholarly journals Pelatihan Teknik Suntik Insulin Pada Keluarga Penderita Diabetes Mellitus Di Dusun Pattiro Desa Paccelekang Kec.Pattalassang Kab.Gowa

2021 ◽  
Vol 4 (5) ◽  
pp. 1109-1116
Author(s):  
Sriwahyuni Sriwahyuni ◽  
Sri Darmawan
Keyword(s):  
Diabetes Mellitus ◽  
Health Education ◽  
World Health Organization ◽  
Health Workers ◽  
Insulin Injection ◽  
World Health ◽  
Injection Technique ◽  
Sugar Levels ◽  
Health Organization ◽  
The Right

ABSTRAK Penyakit Diabetes merupakan salah satu penyakit degeneratif yang terkait langsung dengan gaya hidup atau life style, Menurut World Health Organization (WHO), pada tahun 2014, 8,5% dari orang dewasa berusia 18 tahun dan lebih tua menderita diabetes. Indonesia berdasarkan wawancara yang terdiagnosis dokter sebesar 1,5%, dan Provinsi Sulawesi Selatan pada tahun 2014, jumlah Kasus Diabetes Mellitus (282 penderita) terdiri atas Diabetes mellitus yang terlapor (207 penderita), Diabetes mellitus yang tidak terlapor (160 penderita) dan Diabetes mellitus bergantung insulin (72 penderita) Peran dari tenaga kesehatan dan orang terdekat yang sangat dianggap penting oleh penderita juga sangat mempengaruhi perilaku dalam mengontrol kadar gula darah penderita DM Tipe II, karena jika tidak ada dukungan dan motivasi dan health edukasi dari tenaga kesehatan  serta orang terdekat maka penderita cenderung tidak memperhatikan status kesehatannya. Kegiatan ini sasaran utama adalah keluarga penderita Diabetes Mellitus yang aktif melakukan suntik insulin yang ada di Dusun Pattiro Desa Paccelekang Kec.Pattalassang Kab.Gowa . Salah satu cara yang ditempuh sebelum dilakukan pelatihan adalah dengan melakukan pertemuan dan pendataan terlebih dahulu tentang warga yang memiliki riwayat aktif melakukan suntik insulin. Pelatihan teknik dan keterampilan melakukan suntik insulin yang tepat Daya serap para peserta terhadap materi kegiatan cukup baik, hal ini terlihat dari kemampuan masyarakat menjawab dan mempraktikan Teknik Suntik Insulin..Kata kunci : Health Edukasi, Pelatihan, Suntik Insulin, Diabetes Mellitus  ABSTRACT Diabetes is a degenerative disease that is directly related to lifestyle, according to the World Health Organization (WHO), in 2014, 8.5% of adults aged 18 years and older suffered from diabetes. Indonesia based on interviews with diagnosed doctors by 1.5%, and South Sulawesi Province in 2014, the number of Diabetes Mellitus Cases (282 patients) consisted of reported Diabetes Mellitus (207 cases), Unreported Diabetes Mellitus (160 cases), and Diabetes Insulin-dependent Mellitus (72 patients) The role of health workers and loved ones who are very important to sufferers also greatly affects behavior in controlling blood sugar levels for people with Type II diabetes, because if there is no support and motivation and health education from health workers and those closest to them then sufferers tend not to pay attention to their health status. This activity is the main target for families with Diabetes Mellitus who actively inject insulin in the Pattiro Hamlet, Paccelekang Village, Pattalassang District, Gowa Regency. One of the methods taken before training is to conduct meetings and collect data in advance about residents who have a history of actively injecting insulin. Training on techniques and skills for performing the right insulin injection The participants' absorption of the activity material was quite good, this can be seen from the community's ability to answer and practice the Insulin Injection Technique. Keywords: Health Education, Training, Insulin Injection, Diabetes                   Mellitus

scholarly journals Democracy Backsliding as a Danger of Sustainable Development in the Post-Pandemic Period: Social and Legal aspects of Decision

2021 ◽  
Vol 126 ◽  
pp. 06007
Author(s):  
Oleg Tkach ◽  
Оleh Batrymenko ◽  
Dmytro Nelipa ◽  
Mykola Khylko
Keyword(s):  
Human Life ◽  
Legal Aspects ◽  
World Health ◽  
Global Pandemic ◽  
The World ◽  
The Government ◽  
Democratic Principles ◽  
Health Organization ◽  
The Individual ◽  
The Right

The article considers topical issues of the threat of collapse of democracy. Examples of the democracy collapse have shown the lack of free and fair elections in the world, which threatens the independence of the judiciary, restrictions on the right to freedom of speech, which limits the ability of the political opposition to challenge the government, to prosecute, to offer alternatives to the regime. The collapse of democracy in connection with the spread of COVID-19 is being considered, as the democratic spectrum has repeatedly resorted to excessive control, discriminatory restrictions on freedoms such as movement and assembly, and arbitrary or coercive coercion. Attention is drawn to the fact that the outbreak of coronavirus COVID-19 has led to the introduction in all countries of restrictions on the rights and freedoms of the individual in order to prevent the spread of this infectious disease, declared a global pandemic by the World Health Organization. Thus, the unusual nature of the COVID - 19 coronavirus pandemic poses numerous dilemmas to the public, governments, parliaments, the judiciary, law enforcement and many other actors when it comes to the need for effective protection of health and, ultimately, human life, as well as adherence to and ensuring the fundamental democratic principles of man and society.

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