scholarly journals COVID-19-Associated Case Fatality Rate in Subjects Under 18 Years Old in Mexico, up to December 31, 2020

2021 ◽  
Vol 9 ◽  
Author(s):  
Efraín Navarro-Olivos ◽  
Nicolás Padilla-Raygoza ◽  
Gilberto Flores-Vargas ◽  
María de Jesús Gallardo-Luna ◽  
Ma Guadalupe León-Verdín ◽  
...  

Background: The emergence of the SARS-CoV-2 and the COVID-19 have become a global health crisis. The infection has been present in all the social sectors. Subjects under 18 years are one of them. The objective was to analyze the case fatality ratio of COVID-19 cases in the Mexican population under 18 years of age registered in the National Epidemiological Surveillance System from March 2020 to December 31, 2020.Material and Methods: The design is cross-sectional, quantitative, and analytical. All the suspected cases of respiratory viral disease, with a real-time polymerase chain reaction (RT-PCR) test result, aged from 0 to 17 years, were included. Descriptive statistics are presented for all the variables. Epidemiological curves were designed. The chi-squared test and its P-values were obtained to show the relationship between comorbidities and death. The case fatality ratio was computed for each comorbidity, sex, and age group. Multivariable logistic regression models were fitted to study the effect between comorbidities with the fatality of cases, adjusting for sex and age group as potential confounders. The alpha value was fixed to 0.05 to assess significance.Results: The number of records for this study was 167,856. Among them, 48,505 were from SARS-CoV-2-positive patients (28.90%), and 119,351 (71.10%) were negative. Of those who died, males (55.29%) (P < 0.05) and those under 2 years of age (50.35%) (P < 0.05) predominated. Unlike in older populations, from the comorbidities considered risk factors for death by COVID-19, only immunosuppression showed a statistically significant effect on the fatality of cases after adjustment by the other related variables. Sex and age group were not confounders for the models in those under 18 years old. Pneumonia, being younger than 5 years, and immunosuppression are related to death.Conclusion: The case fatality ratio in those under 18 years old is low. Special attention must be paid to those children under 5 years. The development of pneumonia is a warning indicator while treating them. On the other hand, having an open database of cases allows the researchers to analyze the impact of COVID-19 in different population sectors, which has clear benefits for public health.

2020 ◽  
Author(s):  
Tamba Mina Millimouno ◽  
Mohamed Ali Ag Ahmed ◽  
Birama Apho Ly ◽  
Sana Boukary ◽  
Christophe Laba Faye ◽  
...  

Abstract Background The COVID-19 pandemic is an unprecedented international health crisis with different approaches to the response at country levels. The objective of this study was to analyze the evolution of this pandemic in Guinea, Mali, Senegal, and Burkina Faso over the first six weeks. We hypothesize that there exist significant differences in the incidence of COVID-19 between countries. Methods A cross-sectional study was conducted as part of a collaborative project. Data collection focused on the epidemiological surveillance indicators available in the countries’ COVID-19 daily situation reports. Data were entered into a standardized Microsoft Excel spreadsheet which was exported to the STATA 15 software for analysis. Results COVID-19 had a different dynamic in the four countries over the first six weeks. Its incidence in Burkina Faso and Senegal was dropping, while it was increasing slowly in Mali; only in Guinea, it increased rapidly. The analysis of variance revealed that the differences observed in the weekly COVID-19 incidence in the four countries were statistically significant (p ˂ 0.01). Different screening approaches have been used by the four countries. Guinea (n = 4,539) performed more tests compared to Senegal (n = 2,961), Burkina Faso (n = 2,455) and Mali (n = 2,397). The positivity rates were significantly higher in Mali (25.5%) and Burkina Faso (23.7%) than in Guinea (19.0%) and Senegal (9.5%) (p ˂ 0.0001). Hospitalization rates by country ranged from 32.0–79.6%, with Guinea’s hospitalization rate (79.6%) being significantly higher as compared to that of the three other countries (p ˂ 0.0001). The cure rates were significantly higher in Burkina Faso (61.4%) and Senegal (61.1%) than in Mali (37.3%) and Guinea (19.7%) (p ˂ 0.0001). The case fatality rate was significantly higher in Burkina Faso (6.5%) than in Mali (5.2%) (p ˂ 0.001), Guinea (0.7%), and Senegal (0.7%) (p ˂ 0.0001). Conclusion This study highlighted insights from COVID-19 surveillance data, as a basis for improving response strategies in the four countries. Large-scale screening seems relevant to not only facilitate controlling the disease spread but also reducing case fatality rates by early case detection, prior to the occurrence of complications.


2018 ◽  
Vol 36 (06) ◽  
pp. 653-658 ◽  
Author(s):  
Sindhu Srinivas ◽  
Katy Kozhimannil ◽  
Peiyin Hung ◽  
Laura Attanasio ◽  
Judy Jou ◽  
...  

Background A recent document by the American Congress of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine introduced the concept of uniform levels of maternal care (LMCs). Objective We assessed LMC across hospitals and measured their association with maternal morbidity, focusing on women with high-risk conditions. Study Design We collected data from hospitals from May to November 2015 and linked survey responses to Statewide Inpatient Databases (SID) hospital discharge data in a retrospective cross-sectional study of 247,383 births admitted to 236 hospitals. Generalized logistic regression models were used to examine the associations between hospitals' LMC and the risk of severe maternal morbidity. Stratified analyses were conducted among women with high-risk conditions. Results High-risk pregnancies were more likely to be managed in hospitals with higher LMC (p < 0.001). Women with cardiac conditions had lower odds of maternal morbidity when delivered in level I compared with level IV units (adjusted odds ratio: 0.29; 95% confidence interval: 0.08–0.99; p = 0.049). There were no other significant associations between the LMC and severe maternal morbidity. Conclusion A higher proportion of high-risk pregnancies were managed within level IV units, although there was no overall evidence that these births had superior outcomes. Further prospective evaluation of LMC designation with patient outcomes is necessary to determine the impact of regionalization on maternal outcomes.


2021 ◽  
pp. tobaccocontrol-2020-056451
Author(s):  
Minal Patel ◽  
Alison F Cuccia ◽  
Shanell Folger ◽  
Adam F Benson ◽  
Donna Vallone ◽  
...  

IntroductionLittle is known on whether cigarette filter-related knowledge or beliefs are associated with support for policies to reduce their environmental impact.MethodsA cross-sectional, population-based sample of US adults aged 18–64 years (n=2979) was used to evaluate filter-related knowledge and beliefs by smoking status using data collected between 24 October 2018 and 17 December 2018. Multivariate logistic regression models explored whether these knowledge and belief items were associated with support for two policies, a US$0.75 litter fee and a ban on sales of filtered cigarettes, controlling for demographic characteristics and smoking status.ResultsRegardless of smoking status, 71% did not know plastic was a cigarette filter component and 20% believed filters were biodegradable. Overall, 23% believed filters reduce health harms and 60% believed filters make it easier to smoke; 90% believed cigarette butts are harmful to the environment. Individuals believing cigarette butts harmed the environment were more likely to support a litter fee (adjusted OR (aOR)=2.33, 95% CI: 1.71 to 3.17). Individuals believing that filters are not biodegradable had higher odds of supporting a litter fee (OR=1.47, 95% CI: 1.15 to 1.88). Respondents believing that filters do not make cigarettes less harmful were more likely to support a litter fee (aOR=1.50, 95% CI: 1.20 to 1.88) and filter ban (aOR=2.03, 95% CI: 1.64 to 2.50). Belief that filters make it easier to smoke was associated with decreased support for a filter ban (aOR=0.69, 95% CI: 0.58 to 0.83).ConclusionsComprehensive efforts are needed to educate the public about the impact of cigarette filters in order to build support for effective tobacco product waste policy.


Author(s):  
G. Sanjana ◽  
Vijaya Raghavan

Background: Loneliness can affect anyone at any point in their life. It can be detrimental to the wellbeing and quality of life of individuals and communities. In the ongoing COVID-19 pandemic, loneliness is considered as a public health crisis. Hence, the objectives of the study were to estimate the prevalence of loneliness and family related factors associated with loneliness among general population in south India. Materials and Methods: The study employed a crosssectional online survey design. The data was collected in the first phase of the lockdown in 2020 from adults in Southern India. Socio-demographic profile and family related variables were collected using a semistructured proforma. Loneliness was assessed by UCLA loneliness scale. Results: Of 573 total respondents to the survey, aged between 18-65 years, 43% were male and 57% were female. The overall prevalence of loneliness was 63% (358/573). No significant gender differences were observed in the prevalence of loneliness. Family discord was associated with higher rates of loneliness (p less than 0.01). Other factors associated were younger age and being single. Conclusion: Rates of loneliness during the COVID-19 lockdown were high in Southern India. Findings suggest that interventions should prioritize younger people. Increasing social support and improving interpersonal skills, which in turn would help reduce family discord and may reduce the impact of COVID-19 on loneliness.


Author(s):  
Julianty Pradono ◽  
Sintawati Sintawati

Background<br />Obesity and hypertension are independent risk factors in the increasing prevalence of non-communicable diseases. The proportion of obesity in Indonesia has increased in the last 5 years according to the National Health Survey. The purpose of this research was to obtain the contribution of obesity toward hypertension in the age group of 18 years and above.<br /><br />Methods<br />An observational study of cross-sectional design was conducted using the National Basic Health Research 2013 population data. The total sample of subjects was 2,741,297 from 33 provinces in Indonesia. Data were collected through interviews, blood pressure measurement, and anthropometry. Analysis of categorical data was by means of the chi-square statistical test, followed by calculation of the attributable fraction in the population, and analysis of factors influencing the impact fraction.<br /><br />Results<br />The prevalence of general obesity (BMI&gt;25 kg/m2) was 31.5% in males and 48.0% in females, while central obesity was 20.9% in males and 42.5% in females. In females with general obesity the risk of hypertension was 1.84 (95% CI: 1.82-1.86) times higher than in those with normal BMI. If general obesity and central obesity can be reduced, the prevalence of hypertension may be reduced by 2.9% in males and by 12.2% in females.<br /><br />Conclusion<br />The prevalence of hypertension in the age group of 18 years or more can be reduced by 2.9% in males and by 12.2% in females, by overcoming the contribution of obesity. Therefore efforts should be geared towards promoting healthy eating habits and maintaining a healthy weight through health education.


2020 ◽  
Vol 2 (Number 1) ◽  
pp. 20-23
Author(s):  
Dr. Kamrun Nahar ◽  
Prof. Dr. Belal Ahmed ◽  
Prof. Dr. Md. Khorshed Alam

This was a cross sectional descriptive study conducted to assess the effect pictorial warning message on cigarette packets to the attitude and practice of smokers using a semi-structured questionnaire employing purposive sampling technique with a sample size of 214 by face to face interview carried out in different cities, towns, and villages of Bangladesh from August 2016 to February 2017. Almost 97.6% were male and Most of the respondents (40.9%) belonged to the 20-29 years age group. Majority (58.3%) of them were educated from secondary to graduate few percent below primary. Highest 22.9% respondents were students followed by 17.6% private job holder, 16.9% day labor and only 1.4% was jobless. About 40.2% started smoking by the influence of friends, 26.2% started on curiosity and 20% due to depression and majority 41.0% smoked 1-5 cigarette sticks per day. More than half (65.5%) of respondents felt relax to refreshing by smoking and about two third 77.6% continued their smoking due to habitual act or psychological pleasure Almost 93.4% gave attention to the pictorial warning on the cigarette packets. About 46.4% thought pictorial warning in cigarette packets alarms for not to smoke and only 23.8% thought smoking will cause cancer; 21.4% thought smoking is injurious to health. After seeing the pictorial warning on cigarettes 57.6% reduced the smoking number of sticks per day also attempted to quit smoking. To reduce this restricting the advertisement of tobacco, arranging campaign to raise awareness among people about the health and environmental hazards of smoking and increase the tax on tobacco.


2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Mohammad Sarwar Mir

Background: It is well-known that acne vulgaris is a common malady of adolescence and is easily recognized Objective: To evaluate the level of impact among acne patients on their quality of life. Methods: A total of 200 patients studied. Acne severity was graded using Global Acne Grading System (GAGS) after the clinical diagnosis. All the patients went through self-administered questionnaire of Cardiff Acne Disability Index (CADI) to fill out, to assess the reflection of patients’ experiences and perceptions. Result: Out of 200 patients, 114(57.0%) were females and 86(43.0%) were males. The maximum number of patients was in the age group of 16-20 years (142/200, 71%). Out of total 86 males, 50 (58.3%) had moderate to severe acne, whereas 62(54.38%) females had such a severe acne. 50.87% (58/114) of females had high CADI scores in comparison to only 27.9(24/86) of males. The impact on quality of life was more in the age-group of 21-30 years even though in this age group clinical severity of acne was mild to moderate only. Conclusion: Study found that individuals with acne had profound emotional, as well as, social impact on their quality of life.


Author(s):  
Sandhya Mishra ◽  
Deepak Chopra ◽  
Nidhi Jauhari ◽  
Ausaf Ahmad

Background: Dengue virus infection is a growing health problem and is prevalent throughout India. Research focusing on length of hospital stay and its predictors is scarce from India. This is important considering the burden of the disease during epidemics and impact on hospital admissions. Hence the study was conducted with the objectives to find out the factors influencing the length of stay in hospital of dengue patients.Methods: A cross sectional retrospective observational study conducted at a tertiary care hospital from August 2016 to October 2016. Data was retrieved from case sheets at Medical Record Department of 350 lab confirmed adult dengue patients admitted in the hospital.Results: The majority of patients admitted were of economically productive age group of 18-45 years and males indicating the occupational exposure to the vector of dengue. The study found that majority had length of stay of less than a week and as age increases the length of stay also increases (statistically significant). The nil case fatality and lesser number of mean days of symptoms before admission possibly indicate that early arrival of patients to hospital can lead to very low fatality rates. Further research required to find out the other predictors of length of stay.Conclusions: The study concludes that the dengue affects the economically productive age group and more males thereby indicating occupational exposure to the vector. The age of the patient can be used as an indicator to the length of stay in the hospital.


Materials ◽  
2021 ◽  
Vol 14 (19) ◽  
pp. 5734
Author(s):  
Sebastian Bürklein ◽  
Lennart Zupanc ◽  
David Donnermeyer ◽  
Karsten Tegtmeyer ◽  
Edgar Schäfer

Instrument failure during root canal preparation is still a concern among endodontists. However, it remains unclear whether the use of more martensitic alloys or the cross-sectional design parameters (i.e., core mass) significantly improve fracture resistance. The aim of the study was to evaluate the impact of core mass and alloy on dynamic cyclic fatigue resistance of nickel-titanium endodontic instruments in matching artificial canals at body temperature. Two groups were tested. (A) taper 0.04: F360 (Komet, Lemgo, Germany), Twisted file (Sybron Endo, Glendora, CA, USA) (=TF), JIZAI (Mani, Tochigi, Japan) (=J_04) (all size #25) and the variable tapered TruNatomy (Dentsply, Ballaigues, Switzerland) (size #26) (=TN). (B) size #25; taper 0.06: (Mtwo (VDW, Munich, Germany), JIZAI (Mani) (=J_06), and variable tapered Hyflex EDM OneFile (Coltene Whaledent, Altstätten, Switzerland) (=HF). Time, number of cycles to fracture (NCF), and number and length of fractured fragments were recorded and statistically analysed using ANOVA Student-Newman-Keuls, Kruskal–Wallis or Chi-square test (significance level = 0.05). (A) TN showed the significantly shortest time until fracture, followed by TF, F360 and J_04 which also differed significantly, while NCF showed the following order: F360 < TN < TF < J_04 (p < 0.05). Only one J_04 but all instruments of the other groups fractured within the test-limit of 10 min. (B) Mtwo was significantly inferior concerning time until fracture and NCF, compared to J_06 and HF (p < 0.05), which did not differ significantly (p > 0.05). While all Mtwo instruments fractured, only four instruments failed in the other groups (p < 0.05). Within the limitations of this study, alloy and cross-sectional design (i.e., core mass) were critical factors regarding instrument failure, but none of these factors could be determined as a main parameter for increased or decreased time, and cycles to fracture. Rather, it seemed to be the interaction of multiple factors (e.g., longitudinal and cross-sectional design, alloy, and rotational speed) that was responsible for differences in the time and cycles to fracture. Nonetheless, all instruments had lifetimes that allow safe clinical use. However, the superiority or inferiority of an instrument with regard to cyclic fatigue based on laboratory results—even when identical trajectories are guaranteed—may be considered questionable, as the characteristics and design parameters of the instruments vary considerably, and the experimental setups lack additional clinical parameters and thus clinical relevance.


2020 ◽  
Vol 13 (3) ◽  
pp. 157-167 ◽  
Author(s):  
Justin van der Tas ◽  
Thomas Dodson ◽  
Daniel Buchbinder ◽  
Stefano Fusetti ◽  
Michael Grant ◽  
...  

Study Design: The COrona VIrus Disease-19 (COVID-19) pandemic has disrupted craniomaxillofacial (CMF) surgeons practice worldwide. We implemented a cross-sectional study and enrolled a sample of CMF surgeons who completed a survey. Objective: To measure the impact that COVID-19 has had on CMF surgeons by (1) identifying variations that may exist by geographic region and specialty and (2) measuring access to adequate personal protective equipment (PPE) and identify factors associated with limited access to adequate PPE. Methods: Primary outcome variable was availability of adequate PPE for health-care workers (HCWs) in the front line and surgeons. Descriptive and analytic statistics were computed. Level of statistical significance was set at P < .05. Binary logistic regression models were created to identify variables associated with PPE status (adequate or inadequate). Results: Most of the respondents felt that hospitals did not provide adequate PPE to the HCWs (57.3%) with significant regional differences ( P = .04). Most adequate PPE was available to surgeons in North America with the least offered in Africa. Differences in PPE adequacy per region ( P < .001) and per country ( P < .001) were significant. In Africa and South America, regions reporting previous virus outbreaks, the differences in access to adequate PPE evaporated compared to Europe ( P = .18 and P = .15, respectively). Conclusion: The impact of COVID-19 among CMF surgeons is global and adversely affects both clinical practice and personal lives of CMF surgeons. Future surveys should capture what the mid- and long-term impact of the COVID-19 crisis will look like.


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