scholarly journals Therapeutic Agents for the Treatment of Temporomandibular Joint Disorders: Progress and Perspective

2021 ◽  
Vol 11 ◽  
Author(s):  
Mengjie Wu ◽  
Jingyi Cai ◽  
Yeke Yu ◽  
Sihui Hu ◽  
Yingnan Wang ◽  
...  
Keyword(s):  
Temporomandibular Joint ◽  
Masticatory Muscles ◽  
Therapeutic Agents ◽  
Health Condition ◽  
Delivery Systems ◽  
Temporomandibular Joint Disorders ◽  
Bioactive Molecules ◽  
Functional Disorders ◽  
Mandibular Movement ◽  
Therapy Strategies

Temporomandibular joint disorders (TMD) are a common health condition caused by the structural or functional disorders of masticatory muscles and the temporomandibular joint (TMJ). Abnormal mandibular movement in TMD patients may cause pain, chronic inflammation, and other discomfort, which could be relieved by a variety of drugs through various delivery systems. In this study, we summarized commonly used therapeutic agents in the management of TMD as well as novel bioactive molecules in preclinical stage and clinical trials. The emerging therapy strategies such as novel intra-TMJ delivery systems and implants based on tissue engineering are also discussed. This comprehensive review will strengthen our understanding of pharmacological approaches for TMD therapy.

scholarly journals Dental health of civil aviation flight personnel

2021 ◽  
Vol 25 (1) ◽  
pp. 17-22
Author(s):  
Andrey K. Iordanishvili
Keyword(s):  
Temporomandibular Joint ◽  
Dental Health ◽  
Masticatory Muscles ◽  
Temporomandibular Joint Disorders ◽  
The Body ◽  
Civil Aviation ◽  
Study Group ◽  
Flight Duration ◽  
Dental Diseases ◽  
Masticatory Apparatus

BACKGROUND: Preservation and strengthening of the health of civil aviation flight personnel is an extremely urgent problem and is associated with ensuring flight safety. AIM: This study aimed to determine the structure and analyze the organs and tissues of the masticatory apparatus among civil aviation flight personnel. MATERIALS AND METHODS: To determine the incidence and intensity of main dental diseases and the morbidity structure of organs and tissues of the masticatory apparatus in civil aviation pilots, an in-depth examination was carried out in 120 men aged 2545 years (study group 1) working on various modern passenger and transport aircrafts. The duration of flight operations ranged from 2 to 17 years, with a total flight duration of 140 to 5580 h. The comparison group consisted of 146 men (aged 2545 years) of non-flying specialties (study group 2). The generally accepted methods for assessing the prevalence and intensity of the course of major dental diseases were used. RESULTS: The incidence and intensity of dental disorders, periodontal disease, temporomandibular joint disorders, and parafunctions of the masticatory muscles were defined. The incidence and intensity of major dental diseases among civil aviation flight personnel were clearly directly proportional to their flight time (r=0.547) and duration of work in civil aviation (r=0.482) but to a lesser extent to their age (r=0.416). CONCLUSIONS: Non-carious lesions of the teeth, inflammatory and dystrophic diseases of the periodontal and oral mucosa, painful dysfunction of the temporomandibular joint, and bruxism are more common among civil aviation flight personnel than among non-flying personnel, which is due to the unfavorable effect of air flight factors on organs and tissues of the mastication apparatus and the body of the pilots as a whole.

scholarly journals Nano Drug Delivery Platforms for Dental Application: Infection Control and TMJ Management—A Review

Polymers ◽  
2021 ◽  
Vol 13 (23) ◽  
pp. 4175
Author(s):  
Abhishek Lal ◽  
Mohammad Khursheed Alam ◽  
Naseer Ahmed ◽  
Afsheen Maqsood ◽  
Ruba K. Al-Qaisi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Temporomandibular Joint ◽  
Drug Delivery Systems ◽  
Viral Infections ◽  
Fungal Infections ◽  
Delivery Systems ◽  
Temporomandibular Joint Disorders ◽  
Oral Infections ◽  
Limited Effectiveness ◽  
Nano Drug Delivery

The oral cavity is an intricate environment subjected to various chemical, physical, and thermal injuries. The effectiveness of the local and systemically administered drugs is limited mainly due to their toxicities and poor oral bioavailability that leads to the limited effectiveness of the drugs in the target tissues. To address these issues, nanoparticle drug delivery systems based on metals, liposomes, polymeric particles, and core shells have been developed in recent years. Nano drug delivery systems have applications in the treatment of patients suffering from temporomandibular joint disorders such as preventing degeneration of cartilage in patients suffering from rheumatoid arthritis and osteoarthritis and alleviating the pain along with it. The antibacterial dental applications of nano-drug delivery systems such as silver and copper-based nanoparticles include these agents used to arrest dental caries, multiple steps in root canal treatment, and patients suffering from periodontitis. Nanoparticles have been used in adjunct with antifungals to treat oral fungal infections such as candida albicans in denture wearers. Acyclovir being the most commonly used antiviral has been used in combination with nanoparticles against an array of viral infections such as the herpes simplex virus. Nanoparticles based combination agents offer more favorable drug release in a controlled manner along with efficient delivery at the site of action. This review presents an updated overview of the recently developed nanoparticles delivery systems for the management of temporomandibular joint disorders along with the treatment of different oral infections.

APPRAISING OF KNOWLEDGE, ATTITUDE AND PRACTICE AMONG DENTAL PRACTITIONERS REGARDING ROLE OF PHYSIOTHERAPY IN TEMPOROMANDIBULAR JOINT DISORDERS

2020 ◽  
Vol 8 (2) ◽  
pp. 12-18
Author(s):  
Arsalan Ahmed
Keyword(s):  
Physical Therapy ◽  
Temporomandibular Joint ◽  
Masticatory Muscles ◽  
Temporomandibular Joint Disorders ◽  
Cross Sectional ◽  
Dental Clinics ◽  
Attitude And Practice ◽  
Dental Practitioners ◽  
Knowledge Attitude And Practice

OBJECTIVES The aim is to assess the knowledge, attitude and practice of dental practitioners concerning physiotherapy management of Temporomandibular joint dysfunctions (TMDs.). METHOD 61 dentists were included from Tertiary, secondary and private dental clinics of Karachi, and the study design was cross sectional. RESULTS Prior to survey 45.9% of did not had knowledge about physical therapy management TMD. Maxillofacial surgeons and master’s degree holders had more knowledge about physical therapy (PT) management. 45.9% dentists reported that PT is non-effective treatment approach. Lack of knowledge on dentist’s behalf is the foremost cause of less referral to PT 88.5%. Jaw exercises were prescribed by 83.6% of dentists. In the end of the survey 52.5% dentists were reluctant to refer, 47.5% were maybe they will refer and 96.7% dentists were eager to gain more knowledge about the benefits of PT and collaborative treatment. CONCLUSIONS This study concluded that the dental practitioners of Karachi lack knowledge, attitude and practice regarding physiotherapy treatment of TMD. The benefits of multidisciplinary approach while treating TMDs were not very well known to dental practitioners and its benefits to patients. This study increased the knowledge of surveyed practitioners KEYWORDS Dentistry, Masticatory Muscles, Temporomandibular Joint Disorders, Orthodontics, Temporomandibular Joint, Manipulation

scholarly journals The Application of Manual Techniques in Masticatory Muscles Relaxation as Adjunctive Therapy in the Treatment of Temporomandibular Joint Disorders

2021 ◽  
Vol 18 (24) ◽  
pp. 12970
Author(s):  
Piotr Urbański ◽  
Bartosz Trybulec ◽  
Małgorzata Pihut
Keyword(s):  
Temporomandibular Joint ◽  
Adjunctive Therapy ◽  
Anterior Part ◽  
Masticatory Muscles ◽  
Temporomandibular Joint Disorders ◽  
Spontaneous Pain ◽  
Significant Drop ◽  
Myofascial Release ◽  
Group I ◽  
Masseter Muscles

Temporomandibular disorders (TMD) are primarily characterized by pain as well as disorders concerning the proper functioning of individual elements of the stomatognathic system (SS). The aim of the study was to compare the degree of relaxation of the anterior part of the temporal muscles and the masseter muscles, achieved through the use of post-isometric relaxation and myofascial release methods in patients requiring prosthetic treatment due to temporomandibular joint disorders with a dominant muscular component. Sixty patients who met the inclusion criteria were alternately assigned to one of the two study groups, either group I—patients received post-isometric relaxation treatment (PIR), or group II—patients received myofascial release treatment (MR). The series of ten treatments were performed in both groups. The comparative assessment was based on physiotherapeutic examination, a surface electromyography (sEMG) of the anterior temporal and masseter muscles and the intensity of spontaneous masticatory muscle pain, assessed using the Visual Analogue Scale (VAS). We observed a significant decrease in the electrical activity of examined muscles and a significant drop in the intensity of spontaneous pain in the masticatory muscles both in group I and II. There were no significant differences between groups. Both therapeutic methods may be used as successful forms of adjunctive therapy in the prosthetic treatment of TMD. The trial was registered with an international clinical trials register.

scholarly journals Standardized mastication increases the coordination in masticatory activity in women with chronic temporomandibular joint disorders: a case control study.

2020 ◽  
pp. 1-7
Author(s):  
Carlos Eduardo Fassicollo ◽  
Maylli Daiani Graciosa ◽  
Daiane Lazzeri de Medeiros ◽  
Licerry Palma Soares ◽  
Luis Mochizuki ◽  
...  
Keyword(s):  
Temporomandibular Joint ◽  
Motor Pattern ◽  
Movement Pattern ◽  
Masticatory Muscles ◽  
Temporomandibular Joint Disorders ◽  
Electromyographic Activity ◽  
Emg Signal ◽  
Joint Disorder ◽  
Agonist And Antagonist ◽  
And Control

Background: The effects of jaw movement pattern on masticatory activity during chewing remains unclear in chronic temporomandibular joint disorders individuals. Objective: to assess the effect of habitual and non-habitual mastication patterns based upon the activation of the masseter and temporalis muscles in individuals with or without temporomandibular joint disorder (TMJD). Methods: Fifty-four participants (age: 18–44 years) were divided into two groups: the TMJD (n=27) and control (n=27) groups. TMJD was identified using the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Electromyographic activity of the masticatory muscles was measured during 2 tasks: habitual mastication with parafilm (HM) and non-habitual mastication with parafilm (NHM). MATLAB software was used to process electromyography (EMG) signals. The root mean square, symmetry index (SI%), anteroposterior coefficient (APC%) and torque coefficient (TC%) were determined from the processed EMG signal. Results: Reduced right masseter activation was observed for the TMJD group (p<0.05) during jaw agonist phase. During the jaw agonist phase, all muscles presented with more activation during NHM. Symmetry of temporalis (ST%) and APC% were the lowest for HM. TC% was increased for HM. Conclusion: Habitual and non-habitual mastication differ in masticatory activity during jaw agonist and antagonist phase and TMJD individuals presented a different way to recruit muscles under these circumstances. Non-habitual mastication has a more coordinating and stable motor pattern in masticatory activity and has less variability than habitual mastication to assess masticatory activity.

Frequency of symptoms of temporominal joint dysfunction in children and adolescents in orphanages

2021 ◽  
Vol 1 (223) ◽  
pp. 28-33
Author(s):  
Roza Ibragimova ◽  
◽  
Аssilbek Yessirkepov ◽  
Gulbanu Dosberdiyeva ◽  
Кuralay Zhumabayeva ◽  
...  
Keyword(s):  
Secondary School ◽  
Children And Adolescents ◽  
Temporomandibular Joint ◽  
Comparison Group ◽  
Masticatory Muscles ◽  
Functional Disorders ◽  
Healthy Individuals ◽  
Keywords Temporomandibular Joint ◽  
The City ◽  
Masseter Muscles

Diseases of the temporomandibular joint (TMJ) occur in 20-76% of the population, of which up to 70-89% are functional joint disorders. In children and adolescents, TMJ dysfunction occurs in 14-20%. Among the variety of pathogenetic factors in the development of this pathology, the most important are: stress, psychological disorders, imbalance in the tone of the masticatory muscles, occlusive disharmony. Purpose of the study. To study the prevalence of symptoms of TMJ dysfunction, including prenosological, in children and adolescents living in orphanages. Material and research methods. The frequency of occurrence of symptoms of functional disorders of the TMJ, including prenosological, was studied in 331 children and adolescents living in orphanages. The comparison group consisted of 218 students of secondary school No. 30 in the city of Almaty. Results and discussion. These symptoms were found in 32.62% of children and adolescents living in orphanages in the city of Almaty, and in 35.32% of practically healthy individuals, and their frequency increased with age. More common in girls. In different combinations there were revealed the dislocation of the middle inter-incisive line, pain on palpation of the masseter muscles, joint noise, malopening mouth. Dentofacial anomalies were more often observed in children and adolescents with certain symptoms of functional disorders of the temporomandibular joint. Keywords: temporomandibular joint malfunction, children and adolescents living in orphanages.

Comparison of the diagnostic accuracy of Ultrasonography and CBCT for detection of mandibular condyle erosion (an in-vitro study)

2021 ◽  
Vol 15 (5) ◽  
pp. 1661-1665
Author(s):  
Yasaman Kheirandish ◽  
Mehrdad Panjnoush ◽  
Shabnam Mohammed Charlie ◽  
Elham Romoozi
Keyword(s):  
Temporomandibular Joint ◽  
Mandibular Condyle ◽  
In Vitro Study ◽  
Temporomandibular Joint Disorders ◽  
The Body ◽  
Articular Disc ◽  
Mandibular Movement ◽  
Adequate Treatment ◽  
Bone Changes

Temporomandibular joint (TMJ) is one of the most important, unique and structurally has the highest complex synovial system in the body (1, 2). TMJ, encompassing the temporal bone, mandibular condyle and articular disc, is a diarthrodial joint. As a collective form, Temporomandibular Joint Disorders (TMD) is often with multifactorial etiologies, and these diseases can more commonly affect the soft-tissue components of the TMJ including the articular disc and posterior attachment, the osseous components of the TMJ and also the related muscles (3, 4). The most common cause of the regional orofacial pain of non-dental origin is a result of TMD. Additional symptoms may include TMJ sounds such as clicking, pumping, limited or asymmetric mandibular movement (5). As TMJ is covered by a layer of fibrocartilage, unlike other joints in the human body, the mandibular condyles can be damaged due to cartilage degeneration. In addition, arthritis can also be initiated because of the particular dynamics in the maxillofacial area (6). TMD's are frequently associated with degenerative bone changes which can involve the bone structures of the TMJ such as erosion, flattening, osteophytes, subchondral bone sclerosis and pseudocysts (7). To correctly diagnose the dysfunctions associated with the disease and for adequate treatment planning Knowledge about these bone changes is fundamental (8).

scholarly journals Diagnostic imaging modalities and surgical anatomy of the temporomandibular joint in rabbits

2017 ◽  
Vol 52 (1) ◽  
pp. 38-50
Author(s):  
Michal Kyllar ◽  
Barbora Putnová ◽  
Vladimír Jekl ◽  
Ladislav Stehlík ◽  
Marcela Buchtová ◽  
...  
Keyword(s):  
Temporomandibular Joint ◽  
Masticatory Muscles ◽  
Surgical Anatomy ◽  
Surgical Approaches ◽  
Synovial Joint ◽  
Resonance Imaging ◽  
Mandibular Movement ◽  
Model Species ◽  
Tmj Morphology ◽  
Analytical Approaches

The temporomandibular joint (TMJ) is a condylar synovial joint that, together with the masticatory muscles, controls mandibular movement during mastication. The rabbit is often used as a model species for studying the mechanisms of TMJ diseases, and in regenerative research. However, there are significant differences between rabbit and human TMJs that should be taken into account before using this model for experimental research. Here, we use several analytical approaches (radiography, computed tomography and magnetic resonance imaging) to enable a detailed description and analysis of the rabbit TMJ morphology. Moreover, possible surgical approaches have been introduced with a focus on available access into the rabbit TMJ cavity, which relate our findings to clinical usage.

scholarly journals Evaluation of the Cadiax Compact® II Accuracy in Recording Preadjusted Condylar Inclinations on Fully Adjustable Articulator

2012 ◽  
Vol 13 (4) ◽  
pp. 504-508 ◽  
Author(s):  
Ahmad Hasan Ahangari ◽  
Kianoosh Torabi ◽  
Sasan Rasaei Pour ◽  
Safoura Ghodsi
Keyword(s):  
Clinical Practice ◽  
Temporomandibular Joint ◽  
Movement Analysis ◽  
Temporomandibular Joint Disorders ◽  
Maximum Difference ◽  
Mandibular Movement ◽  
Articular Eminence ◽  
Critical Step ◽  
Reliable Instrument ◽  
Comparison Of The Results

ABSTRACT Background Mandibular movement analysis is a critical step in making the functional occlusal morphology and improving the diagnosis and treatment of temporomandibular joint disorders (TMDs). Cadiax Compact® is an electronic condylograph that claims to record the horizontal condylar inclination (HCI), Bennett angle (BA) and relative shape of the articular eminence. This study aims at assessing the accuracy of Cadiax Compact® II in its claimed abilities. Materials and methods The electronic condylograph (Cadiax Compact®II) was fitted on the fully adjustable articulator (gamma dental reference- SL). After setting of HCI and BA on the arbitrary degrees, eccentric movements were produced manually on the articulator. The Cadiax recorded these preadjusted angles and the accuracy of its recordings was assessed by comparison of the results with the preadjusted HCI, BA and color inserts as references. Results The majority of the comparisons showed statistically significant differences between articulator settings and Cadiax recordings. However, the maximum difference was about 2.5° which seems acceptable for clinical practice. Conclusion The obtained results showed that Cadiax Compact is an accurate and reliable instrument for diagnostic purposes, yielding reproducible measurements. Despite this, Cadiax is a technically sensitive device that can preclude its routine usage. How to cite this article Ahangari AH, Torabi K, Pour SR, Ghodsi S. Evaluation of the Cadiax Compact® II Accuracy in Recording Preadjusted Condylar Inclinations on Fully Adjustable Articulator. J Contemp Dent Pract 2012;13(4):504-508.

scholarly journals Cervical spine range of motion, posture and electromyographic activity of masticatory muscles in temporomandibular disorders

2020 ◽  
Vol 33 ◽  
Author(s):  
Franciele Aparecida Amaral ◽  
Simone Mader Dall’Agnol ◽  
Gabriela Socolovski ◽  
Camila Kich ◽  
Gilson Cesar Nobre Franco ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Temporomandibular Joint ◽  
Work Ability ◽  
Temporomandibular Disorders ◽  
Masticatory Muscles ◽  
Temporomandibular Joint Disorders ◽  
Pain Level ◽  
Jaw Function ◽  
The Right ◽  
Cervical Rotation

Abstract Introduction: Temporomandibular joint disorders (TMD or TMJD) involve clinical problems and symptoms affecting the temporomandibular joint (TMJ) and associated structures. The temporomandibular joints are anatomically connected to the cervical region, where cervical spine movements occur simultaneously to masticatory muscle activation and jaw movements. Objective: Our study sought to assess the relationship between the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD), surface electromyography (sEMG) of the masticatory muscles, posture and cervical flexibility in women with TMD. Method: Fifty women with an average age of 27.0 ± 6.37 years, diagnosed with TMD according to RDC/TMD, were assessed for craniocervical posture, cervical flexibility and sEMG of the masticatory muscles. Results: There were no differences in jaw function limitations, depression, pain level and its interference in work ability and daily activities, posture and sEMG between TMD diagnoses or between muscle classification (p > 0.05). Depression scores were higher among participants with biarticular dysfunction (p = 0.023). The group with bruxism exhibited a higher pain level at assessment (p = 0.001) and a greater reduction in work ability (p = 0.039). Subjects with muscular and mixed TMD showed less cervical rotation to the right when compared with those with articular TMD. Conclusion: There was no difference in posture or sEMG values for TMD diagnoses, joint and muscle dysfunctions and the presence of bruxism. Muscle dysfunction is associated with reduced cervical rotation to the right. Jaw function limitations did not interfere in posture or sEMG and depression was associated with pain.

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