scholarly journals Potential Association Between the Low-Energy Plasma Structure and the Patchy Pulsating Aurora

2021 ◽  
Vol 8 ◽  
Author(s):  
Jun Liang ◽  
Y. Nishimura ◽  
E. Donovan ◽  
B. Yang ◽  
V. Angelopoulos
Keyword(s):  
Cold Plasma ◽  
Low Energy ◽  
Future Research ◽  
Topside Ionosphere ◽  
Plasma Structure ◽  
Main Class ◽  
New Perspective ◽  
Underlying Mechanisms ◽  
Auroral Phenomena ◽  
Generation Mechanisms

While the pulsating auroral phenomena have been recognized and studied for decades, our understating of their generation mechanisms remains incomplete to date. In one main class of pulsating auroras which is termed “patchy pulsating auroras” (PPA), the auroral patches are found to basically maintain their shape and size over many pulsation cycles. Also, PPAs are repeatedly found to essentially co-move with the ExB convection drift. The above properties led many researchers to hypothesize that PPA might connect to a structure of enhanced cold plasma in the magnetosphere. In this study, we review the existing evidence, and provide new perspective and support, of the low-energy plasma structure potentially associated with PPA. Based on observations from both the magnetosphere and the topside ionosphere, we suggest that ionospheric auroral outflows might constitute one possible source mechanism of the flux tubes with enhanced low-energy plasma that connect to the PPA. We also review the existing theories of pulsating auroras, with particular focus on the role of low-energy plasma in these theories. To date, none of the existing theories are complete and mature enough to offer a quantitatively satisfactory explanation of pulsating auroras. At last, we suggest a few future research directions to advance our understanding of pulsating auroras: a) more accurate measurements of the cold plasma density, b) more developed theories of the underlying mechanisms of ELF/VLF wave modulation, and c) auxiliary processes in the topside ionosphere or near-Earth region accompanying pulsating auroras.

scholarly journals Investigating mindfulness influences on cognitive function: On the promise and potential of converging research strategies

2021 ◽  
Author(s):  
Yanli Lin ◽  
Rongxiang Tang ◽  
Todd Samuel Braver
Keyword(s):  
Public Interest ◽  
Systematic Approach ◽  
Future Research ◽  
Research Strategies ◽  
The Past ◽  
New Perspective ◽  
Underlying Mechanisms ◽  
Taxonomic Framework ◽  
Mechanisms Of Mindfulness ◽  
Organizing Principles

Research investigating the effects and underlying mechanisms of mindfulness on cognitive functioning has accelerated exponentially over the past two decades. Despite the rapid growth of the literature and its influential role in garnering public interest in mindfulness, inconsistent methods in defining and measuring mindfulness have yielded variable findings, which contribute to the overall dearth of clear generalizable conclusions. The focus of this article is to address the lack of cohesion in the collective methodologies used in this domain, by providing a new perspective grounded in classic cognitive and experimental psychology principles. We leverage the concept of converging operations to demonstrate how seemingly disparate research strategies can be integrated towards a more unified and systematic approach. An organizing taxonomic framework is described to provide useful structure in how mindfulness can be operationalized, measured, and investigated. We illustrate the rationale and core organizing principles of the framework through a selective review of studies on mindfulness and cognitive control. We then demonstrate the utility of the approach by showing how it can be applied to synthesize extant methodologies and guide the development of future research. Specific suggestions and examples pertaining to experimental design and statistical analysis are provided.

scholarly journals Neuroimmunological Responses to Social Isolation

2015 ◽  
Vol 17 (1) ◽  
pp. 10 ◽  
Author(s):  
Karol Ramirez DDS, MSc, PhD
Keyword(s):  
Social Isolation ◽  
Social Stress ◽  
Inflammatory Diseases ◽  
Psychosocial Stressors ◽  
Future Research ◽  
Chronic Activation ◽  
New Perspective ◽  
Underlying Mechanisms ◽  
Perceived Social Isolation ◽  
Pituitary Adrenal Axis

Objective social isolation and perceived social isolation are psychosocial stressors that may impair the normal functioning of the neuroimmune system. Chronic activation of the neuro-immuno-endocrine communication and the consequent loss of homeostasis may lead to the appearance of pathologies and associated mood disorders. For example, alterations in the hypothalamic-pituitary- adrenal axis and sympathetic nervous system dynamics may account for the observed predisposition to inflammatory diseases following chronic social stress. Therefore, it is necessary to further study the underlying mechanisms in social isolation in order to prevent its deleterious effects on health. The objective of this New Perspective article is to supplement the understanding of the neuroimmunological responses to social isolation and provide a basis for future research in this topic. 

scholarly journals Research and application progress of lignin-based composite membrane

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Youjing Li ◽  
Fen Li ◽  
Ying Yang ◽  
Baocai Ge ◽  
Fanzhu Meng
Keyword(s):  
Environmental Pollution ◽  
Raw Materials ◽  
Waste Product ◽  
Functional Materials ◽  
Polymeric Materials ◽  
Composite Membranes ◽  
Organic Polymer ◽  
Future Research ◽  
Sustainable Resources ◽  
New Perspective

Abstract In view of the serious environmental pollution, which is the greatest problem the world is facing, and the continuous consumption of raw materials, it is imminent to search for green and sustainable resources. Lignin is an organic polymer that exists widely in nature, and if it can be transformed from traditional low-value waste product with low range of applications to functional materials with high application prospects, it can be of great significance to alleviate environmental pollution and shortage of fossil resources. One of the functional applications of lignin involves its use to fabricate composite with other polymeric materials, which can then be used to prepare membrane materials. This review summarizes the recent research and application progress of combining lignin with polypropylene, polyvinyl alcohol, starch, cellulose, chitosan, and other polymeric materials to prepare composite membranes; and summarizes the future development direction of lignin-based composite membranes. We hope this review may provide a new perspective to the understanding of lignin-based composite membranes and a useful reference for future research.

scholarly journals Structural and Functional Remodeling of Mitochondria in Cardiac Diseases

2021 ◽  
Vol 22 (8) ◽  
pp. 4167
Author(s):  
Xiaonan Sun ◽  
Jalen Alford ◽  
Hongyu Qiu
Keyword(s):  
Regulatory Network ◽  
Molecular Basis ◽  
Therapeutic Potential ◽  
Research Direction ◽  
Future Research ◽  
Cardiac Diseases ◽  
Functional Remodeling ◽  
Underlying Mechanisms ◽  
Mitochondrial Remodeling ◽  
Normal Cellular Function

Mitochondria undergo structural and functional remodeling to meet the cell demand in response to the intracellular and extracellular stimulations, playing an essential role in maintaining normal cellular function. Merging evidence demonstrated that dysregulation of mitochondrial remodeling is a fundamental driving force of complex human diseases, highlighting its crucial pathophysiological roles and therapeutic potential. In this review, we outlined the progress of the molecular basis of mitochondrial structural and functional remodeling and their regulatory network. In particular, we summarized the latest evidence of the fundamental association of impaired mitochondrial remodeling in developing diverse cardiac diseases and the underlying mechanisms. We also explored the therapeutic potential related to mitochondrial remodeling and future research direction. This updated information would improve our knowledge of mitochondrial biology and cardiac diseases’ pathogenesis, which would inspire new potential strategies for treating these diseases by targeting mitochondria remodeling.

scholarly journals Thermoplastic Pultrusion: A Review

Polymers ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 180
Author(s):  
Kirill Minchenkov ◽  
Alexander Vedernikov ◽  
Alexander Safonov ◽  
Iskander Akhatov
Keyword(s):  
Composite Structures ◽  
Raw Materials ◽  
Thermoplastic Composites ◽  
Future Research ◽  
Transportation Industry ◽  
Architectural Engineering ◽  
Simulation Techniques ◽  
New Perspective ◽  
The Many ◽  
Lower Production

Pultrusion is one of the most efficient methods of producing polymer composite structures with a constant cross-section. Pultruded profiles are widely used in bridge construction, transportation industry, energy sector, and civil and architectural engineering. However, in spite of the many advantages thermoplastic composites have over the thermoset ones, the thermoplastic pultrusion market demonstrates significantly lower production volumes as compared to those of the thermoset one. Examining the thermoplastic pultrusion processes, raw materials, mechanical properties of thermoplastic composites, process simulation techniques, patents, and applications of thermoplastic pultrusion, this overview aims to analyze the existing gap between thermoset and thermoplastic pultrusions in order to promote the development of the latter one. Therefore, observing thermoplastic pultrusion from a new perspective, we intend to identify current shortcomings and issues, and to propose future research and application directions.

A Comprehensive Survey of Neural Architecture Search

2021 ◽  
Vol 54 (4) ◽  
pp. 1-34
Author(s):  
Pengzhen Ren ◽  
Yun Xiao ◽  
Xiaojun Chang ◽  
Po-yao Huang ◽  
Zhihui Li ◽  
...  
Keyword(s):  
Research Work ◽  
Search Space ◽  
Feature Representation ◽  
Future Research ◽  
Related Research ◽  
Neural Architecture ◽  
Comprehensive Survey ◽  
Future Research Directions ◽  
Intuitive Idea ◽  
New Perspective

Deep learning has made substantial breakthroughs in many fields due to its powerful automatic representation capabilities. It has been proven that neural architecture design is crucial to the feature representation of data and the final performance. However, the design of the neural architecture heavily relies on the researchers’ prior knowledge and experience. And due to the limitations of humans’ inherent knowledge, it is difficult for people to jump out of their original thinking paradigm and design an optimal model. Therefore, an intuitive idea would be to reduce human intervention as much as possible and let the algorithm automatically design the neural architecture. Neural Architecture Search ( NAS ) is just such a revolutionary algorithm, and the related research work is complicated and rich. Therefore, a comprehensive and systematic survey on the NAS is essential. Previously related surveys have begun to classify existing work mainly based on the key components of NAS: search space, search strategy, and evaluation strategy. While this classification method is more intuitive, it is difficult for readers to grasp the challenges and the landmark work involved. Therefore, in this survey, we provide a new perspective: beginning with an overview of the characteristics of the earliest NAS algorithms, summarizing the problems in these early NAS algorithms, and then providing solutions for subsequent related research work. In addition, we conduct a detailed and comprehensive analysis, comparison, and summary of these works. Finally, we provide some possible future research directions.

scholarly journals PHYSIOLOGY OF SUCCESSFUL AGING: IMPLICATIONS FOR HEALTH AND WELL-BEING

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S434-S434
Author(s):  
Konstantinos Mantantzis ◽  
Denis Gerstorf ◽  
Thomas M Hess
Keyword(s):  
Older Adults ◽  
Successful Aging ◽  
Well Being ◽  
Empathic Accuracy ◽  
Future Research ◽  
Subjective Well Being ◽  
Use Of Data ◽  
Aging Study ◽  
Underlying Mechanisms ◽  
Relationship Factors

Abstract Research into peripheral physiology and its association with cognition, emotionality, and social/physical functioning has received considerable attention over the years. However, many of the underlying mechanisms are not well understood. In this symposium, we have compiled a set of four empirical projects that showcase current and future endeavors to address some of the long-standing questions about when, how, and why physiology shapes and is shaped by key psychosocial resources. Hawkley et al. make use of data from the NSHAP and HRS longitudinal studies to investigate whether social relationships such as number of friends predicts risk of diabetes among older adults. Wilson et al. use dyadic data from young and middle-aged couples to examine cardiometabolic similarity among spouses, and how such concordance is shaped by key relationship factors such as emotional closeness. Pauly et al. use data from two daily-life studies of older couples to investigate how physiological synchrony in cortisol is modulated by partner interactions, empathy, and empathic accuracy. Finally, Mantantzis et al. make use of multi-year longitudinal data from the Berlin Aging Study II to examine the role of glucose regulation capacity for trajectories of subjective well-being among older adults. Thomas Hess will discuss the importance of these papers, discuss strengths and weaknesses of the approaches chosen, and consider implications for future research.

Business-IT Alignment Literature Review

2018 ◽  
Vol 31 (3) ◽  
pp. 34-53 ◽  
Author(s):  
Yu Jia ◽  
Nianxin Wang ◽  
Shilun Ge
Keyword(s):  
Citation Analysis ◽  
Knowledge Flows ◽  
Intellectual Structure ◽  
Future Research ◽  
Research Directions ◽  
It Alignment ◽  
Research Themes ◽  
Future Research Directions ◽  
Business It Alignment ◽  
New Perspective

The purpose of this article is to portray the knowledge evolution paths of business-IT alignment (BITA) research and identify a set of important papers in the development of BITA, and elucidate the intellectual structure of this field. This study collected 309 papers published during the period 1983-2015 from the Web of Science (WOS) database. Using a variety of bibliometric and visualization analytic techniques such as citation analysis, co-citation analysis and main path analysis, this article (1) delineates the significant knowledge flows of BITA research and identifies 15 important papers in this field; (2) graphically maps the influential countries, institutions, and journals of BITA research; (3) identifies four major research themes: BITA model, measurement, antecedents, and dynamics, and visualizing the relationships among them. Based on these findings, recommendations for the future research directions have suggested. This article provides IT practitioners, executives, and scholars with a new perspective to get a better understanding of BITA.

scholarly journals Difficulty in implementing continuous improvement – Rasch measurement analysis

2019 ◽  
Vol 25 (6) ◽  
pp. 1228-1250 ◽  
Author(s):  
Lidia Sanchez-Ruiz ◽  
Beatriz Blanco ◽  
Emma Diaz
Keyword(s):  
Continuous Improvement ◽  
Measurement Theory ◽  
Reliability And Validity ◽  
Rasch Measurement ◽  
Point Of View ◽  
Future Research ◽  
Theoretical Point ◽  
Content Type ◽  
Level Of Difficulty ◽  
New Perspective

Purpose The purpose of this paper is to define a general and common construct in order to measure the level of difficulty companies experience when they implement continuous improvement (CI). Additionally, a rank of barriers is obtained together with a rank of companies. Design/methodology/approach In order to achieve the objective, first, a literature review is carried out to specify the domain of the construct; second, a sample of items is selected; third a survey is carried out in companies that have already implemented CI initiatives, the results being thus limited to this population; fourth, measures are purified by analysing the reliability and validity of the measurements, and finally results are obtained. The Rasch measurement theory will be used to provide a new perspective on a mature research topic. Findings It can be concluded that a new valid construct has been defined together with a rank of CI barriers, being lack of time the main barrier. A rank of companies is also obtained which is a first step in the development of future research studies. Practical implications Managers are provided with a better understanding of the barriers that can obstruct CI implementation. Thus, the rank of CI barriers guides managers through the most common and important obstacles so that they will be able to plan better CI strategies. In addition, the rank of companies allows each company to undertake a benchmarking exercise. Originality/value This work proposes a new way of analysing the difficulty in implementing CI as a continuum, rather than as independent barriers. From a theoretical point of view, it defines a new construct and offers a rank of CI barriers together with a rank of companies based on their level of difficulty when implementing CI initiatives. This is something new, as previous studies were mainly focussed on the items side. From a practical point of view, this study offers the surveyed companies the opportunity to see how they are positioned with respect to the other companies. Moreover, this rank of companies is the foundation on which to develop further studies with a practical orientation in the future.

scholarly journals Intestinal Absorption Profile of Three Polygala Oligosaccharide Esters in Polygalae Radix and the Effects of Other Components in Polygalae Radix on Their Absorption

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
YinYing Ba ◽  
MengLin Wang ◽  
KunFeng Zhang ◽  
QiJun Chen ◽  
JiaJia Wang ◽  
...  
Keyword(s):  
Future Research ◽  
Active Components ◽  
Sodium Caprate ◽  
P Glycoprotein ◽  
Paracellular Absorption ◽  
Underlying Mechanisms ◽  
The Relationship ◽  
Rat Gut ◽  
Human Nervous System

Oligosaccharide esters, which are among the main active components of Polygalae Radix (PR), demonstrate significant pharmacological activities in the human nervous system. In our previous research, some other constituents in PR were able to improve the bioavailability of oligosaccharide esters such as sibiricose A5 (SA5), sibiricose A6 (SA6), and 3,6′-disinapoyl sucrose (DISS), but the related components and their underlying mechanisms remain unknown. The present study aimed to investigate the intestinal absorptive profile of SA5, SA6, and DISS and the absorptive behavior influenced by the coadministration of polygalaxanthone III and total saponins of PR (TS) using an in vitro everted rat gut sac model, along with the possible mechanisms that may influence absorption. The results showed that TS could significantly enhance the absorption of SA5, SA6, and DISS monomers. Verapamil, a P-glycoprotein inhibitor, was able to elevate the absorption of SA5 and SA6, and an absorption experiment using Rho123 led us to conclude that TS influenced the absorption of SA5 and SA6 in a manner similar to that of a P-glycoprotein inhibitor. Sodium caprate, a paracellular absorption enhancer, was found to increase the absorption of SA5, SA6, and DISS. Results showed that the absorption mechanisms of SA5 and SA6 may combine active transport with paracellular passive penetration, while DISS’s absorption was dominated by paracellular passive penetration. However, the relationship between polygala saponins and the absorption of SA5, SA6, and DISS by paracellular passive penetration remain to be examined. This is the direction of our future research.

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