Plasma Medicine Technologies

This Special Issue, entitled “Plasma Medicine Technologies”, covers the latest remarkable developments in the field of plasma bioscience and medicine. Plasma medicine is an interdisciplinary field that combines the principles of plasma physics, material science, bioscience, and medicine, towards the development of therapeutic strategies. A study on plasma medicine has yielded the development of new treatment opportunities in medical and dental sciences. An important aspect of this issue is the presentation of research underlying new therapeutic methods that are useful in medicine, dentistry, sterilization, and, in the current scenario, that challenge perspectives in biomedical sciences. This issue is focused on basic research on the characterization of the bioplasma sources applicable to living cells, especially to the human body, and fundamental research on the mutual interactions between bioplasma and organic–inorganic liquids, and bio or nanomaterials.

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Novel Targets and Therapeutic Strategies for Promoting Organ Repair and Regeneration

Biomolecules ◽

10.3390/biom10050749 ◽

2020 ◽

Vol 10 (5) ◽

pp. 749

Author(s):

Shanmugam Muruganandan ◽

Michael Wigerius

Keyword(s):

Stem Cell ◽

Regenerative Medicine ◽

Drug Administration ◽

Treatment Options ◽

Therapeutic Strategies ◽

Clinical Settings ◽

Special Issue ◽

Organ Repair ◽

Novel Targets ◽

New Treatment

Strategies to create functional organs and tissues is of great interest for use in regenerative medicine in order to repair or replace the lost tissues due to injury, disease, as well as aging. Several new treatment options, including stem cell treatments and tissue-engineered substitutes for certain indications, have been approved by Food and Drug Administration (FDA) and are currently available. This special issue will cover new therapies and strategies that are currently being investigated under preclinical and clinical settings.

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Protein Solvent Interaction: Transition of Protein-solvent Interaction Concept from Basic Research into Solvent Manipulation of Chromatography

Current Protein and Peptide Science ◽

10.2174/1389203718666171024121529 ◽

2018 ◽

Vol 20 (1) ◽

pp. 34-39 ◽

Cited By ~ 1

Author(s):

Tsutomu Arakawa ◽

Yoshiko Kita

Keyword(s):

Column Chromatography ◽

Rapid Development ◽

Academic Research ◽

Basic Research ◽

Protein Stabilization ◽

Special Issue ◽

Solvent Interaction ◽

Protein Formulations ◽

Solvent Additive ◽

Downstream Processes

Previously, we have reviewed in this journal (Arakawa, T., Kita, Y., Curr. Protein Pept. Sci., 15, 608-620, 2014) the interaction of arginine with proteins and various applications of this solvent additive in the area of protein formulations and downstream processes. In this special issue, we expand the concept of protein-solvent interaction into the analysis of the effects of solvent additives on various column chromatography, including mixed-mode chromatography. Earlier in our research, we have studied the interactions of such a variety of solvent additives as sugars, salts, amino acids, polymers and organic solvents with a variety of proteins, which resulted in mechanistic understanding on their protein stabilization and precipitation effects, the latter known as Hofmeister series. While such a study was then a pure academic research, rapid development of genetic engineering technologies and resultant biotechnologies made it a valuable knowledge in fully utilizing solvent additives in manipulation of protein solution, including column chromatography.

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Editorial for Special Issue “Historical Mineral Pigments”

Minerals ◽

10.3390/min11030237 ◽

2021 ◽

Vol 11 (3) ◽

pp. 237

Author(s):

Carolina Cardell ◽

Jose Santiago Pozo-Antonio

Keyword(s):

Chemical Characterization ◽

Glass Enamel ◽

Special Issue ◽

High Quality ◽

Physical Chemical ◽

Scientific Disciplines ◽

Natural And Synthetic

The physical–chemical characterization of natural and synthetic historical inorganic and mineral pigments, which may be found embedded in paintings (real or mock-ups), glass, enamel, ceramics, beads, tesserae, etc., as well as their alteration under different decay scenarios, is a demanding line of investigation. This field of research is now both well established and dynamic, as revealed by the numerous publications in high-quality journals of varied scientific disciplines. [...]

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Special Issue: Advances in Computational Electromagnetics

Magnetochemistry ◽

10.3390/magnetochemistry7060089 ◽

2021 ◽

Vol 7 (6) ◽

pp. 89

Author(s):

Valerio De Santis

Keyword(s):

Rare Earth ◽

Magnetic Materials ◽

Permanent Magnets ◽

Computational Electromagnetics ◽

Superconducting Materials ◽

Special Issue ◽

Full Characterization ◽

Recent Advances

Recent advances in computational electromagnetics (CEMs) have made the full characterization of complex magnetic materials possible, such as superconducting materials, composite or nanomaterials, rare-earth free permanent magnets, etc [...]

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Emerging Natural-Product-Based Treatments for the Management of Osteoarthritis

Antioxidants ◽

10.3390/antiox10020265 ◽

2021 ◽

Vol 10 (2) ◽

pp. 265

Author(s):

Maria-Luisa Pérez-Lozano ◽

Annabelle Cesaro ◽

Marija Mazor ◽

Eric Esteve ◽

Sabine Berteina-Raboin ◽

...

Keyword(s):

Bone Resorption ◽

Natural Product ◽

Treatment Strategies ◽

Cartilage Degradation ◽

Therapeutic Strategies ◽

Clinical Models ◽

Osteoarthritic Joint ◽

Dietary Components ◽

New Treatment ◽

Review Current

Osteoarthritis (OA) is a complex degenerative disease in which joint homeostasis is disrupted, leading to synovial inflammation, cartilage degradation, subchondral bone remodeling, and resulting in pain and joint disability. Yet, the development of new treatment strategies to restore the equilibrium of the osteoarthritic joint remains a challenge. Numerous studies have revealed that dietary components and/or natural products have anti-inflammatory, antioxidant, anti-bone-resorption, and anabolic potential and have received much attention toward the development of new therapeutic strategies for OA treatment. In the present review, we provide an overview of current and emerging natural-product-based research treatments for OA management by drawing attention to experimental, pre-clinical, and clinical models. Herein, we review current and emerging natural-product-based research treatments for OA management.

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Proceedings of the GDR Vertige 2019 annual meeting devoted to endolymphatic hydrops

Journal of Vestibular Research ◽

10.3233/ves-200797 ◽

2021 ◽

pp. 1-3

Author(s):

Christian Chabbert ◽

Anne Charpiot

Keyword(s):

Annual Meeting ◽

Research Group ◽

Endolymphatic Hydrops ◽

Clinical Manifestations ◽

Vestibular Function ◽

Therapeutic Strategies ◽

Vestibular Disorders ◽

Special Issue ◽

Clinical Imaging ◽

New Methods

The GDR Vertige is a federative research group gathering the different components of the French neuro-otology community. The annual meeting of the GDR Vertige is an opportunity for interactive exchanges between scientists, clinicians and industrialists, on basic issues related to vestibular function, as well as translational questions regarding the management of vestibular disorders. For its fifth edition, the annual meeting of the GDR Vertige, which took place in September 2019 in Marseille (France), was devoted to one of the most peculiar phenomena of neuro-otology: endolymphatic hydrops. For two days, international scientists and clinicians presented the most recent advances regarding the biophysical correlates of endolymphatic hydrops, the genetic and endocrine tableaux that favor its manifestation, new methods of clinical imaging, and current and upcoming therapeutic strategies to overcome the associated clinical manifestations. This special issue of the Journal of Vestibular Research aims at providing the proceedings of this meeting.

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Fundamental Research—Reporting cutting-edge basic research to the world

Fundamental Research ◽

10.1016/j.fmre.2021.01.006 ◽

2021 ◽

Vol 1 (1) ◽

pp. 1

Author(s):

Qi-Huang Gong

Keyword(s):

Basic Research ◽

Cutting Edge ◽

Research Reporting ◽

The World ◽

Fundamental Research

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Sphingolipid lysosomal storage diseases: from bench to bedside

Lipids in Health and Disease ◽

10.1186/s12944-021-01466-0 ◽

2021 ◽

Vol 20 (1) ◽

Author(s):

Muna Abed Rabbo ◽

Yara Khodour ◽

Laurie S. Kaguni ◽

Johnny Stiban

Keyword(s):

Basic Research ◽

Lysosomal Storage Diseases ◽

Therapeutic Strategies ◽

Clinical Applications ◽

Late Nineteenth Century ◽

Lysosomal Storage ◽

Storage Diseases ◽

The Past ◽

Health And Disease ◽

General Aspects

AbstractJohann Ludwig Wilhelm Thudicum described sphingolipids (SLs) in the late nineteenth century, but it was only in the past fifty years that SL research surged in importance and applicability. Currently, sphingolipids and their metabolism are hotly debated topics in various biochemical fields. Similar to other macromolecular reactions, SL metabolism has important implications in health and disease in most cells. A plethora of SL-related genetic ailments has been described. Defects in SL catabolism can cause the accumulation of SLs, leading to many types of lysosomal storage diseases (LSDs) collectively called sphingolipidoses. These diseases mainly impact the neuronal and immune systems, but other systems can be affected as well. This review aims to present a comprehensive, up-to-date picture of the rapidly growing field of sphingolipid LSDs, their etiology, pathology, and potential therapeutic strategies. We first describe LSDs biochemically and briefly discuss their catabolism, followed by general aspects of the major diseases such as Gaucher, Krabbe, Fabry, and Farber among others. We conclude with an overview of the available and potential future therapies for many of the diseases. We strive to present the most important and recent findings from basic research and clinical applications, and to provide a valuable source for understanding these disorders.

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