scholarly journals Rosmarinic Acid and Ulvan from Terrestrial and Marine Sources in Anti-Microbial Bionanosystems and Biomaterials

2021 ◽  
Vol 11 (19) ◽  
pp. 9249
Author(s):  
Serena Coiai ◽  
Beatrice Campanella ◽  
Roberta Paulert ◽  
Francesca Cicogna ◽  
Emilia Bramanti ◽  
...  
Keyword(s):  
Consumer Goods ◽  
Rosmarinic Acid ◽  
Scientific Literature ◽  
Functional Materials ◽  
Present Review ◽  
Terrestrial Plants ◽  
Microbial Polysaccharide ◽  
Inorganic Substrates ◽  
Functional Biomaterials ◽  
Microbial Agent

In order to increase their sustainability, antimicrobial renewable molecules are fundamental additions to consumer goods. Rosmarinic acid is extracted from several terrestrial plants and represents an effective anti-microbial agent. Ulvan, extracted from algae, is an anti-microbial polysaccharide. The present review is dedicated to discussing the sources and the extraction methodologies for obtaining rosmarinic acid and ulvan. Moreover, the preparation of bioanosystems, integrating the two molecules with organic or inorganic substrates, are reviewed as methodologies to increase their effectiveness and stability. Finally, the possibility of preparing functional biomaterials and anti-microbial final products is discussed, considering scientific literature. The performed analysis indicated that the production of both molecules is not yet performed with mature industrial technologies. Nevertheless, both molecules could potentially be used in the packaging, biomedical, pharmaceutical, cosmetic, sanitary and personal care sectors, despite some research being required for developing functional materials with specific properties to pave the way for many more applications.

Nanoscale Functional Biomaterials for Cancer Theranostics

2018 ◽  
Vol 25 (25) ◽  
pp. 2987-3000 ◽  
Author(s):  
Linying Liu ◽  
Xiaoshuang Li ◽  
Lei Chen ◽  
Xin Zhang
Keyword(s):  
Brain Cancer ◽  
Molecular Level ◽  
Functional Materials ◽  
Therapeutic Agents ◽  
Lower Side ◽  
Drug Delivery Vehicles ◽  
Functional Nanoparticles ◽  
Delivery Vehicles ◽  
Functional Biomaterials ◽  
Cancer Theranostics

Nanomedicine is widely developed in recent years. In nanomedicine system, nanoscale and nanostructured functional materials are used to manipulate the human biology systems at the molecular level for cancer imaging and therapy. New nanostructure based functional materials consist of nanoscale liposomes, spheres, micelles, capsules, emulsion, suspension and phamacosomes. Several functional nanoparticles such as lipidbased and polymer-based materials are demonstrated to be drug delivery vehicles and imaging agents. These materials are biodegradable, biocompatible and have better biodistribution, lower side effect and lower toxicity. In addition, hybrids with these materials coating provide uniquely electrical, optical and magnetic properties. This review discusses the research on the applications of functional materials, especially nanoparticles as imaging contrast agents, cancer therapeutic agents and multi-functional agents and this review focused on the theranostic integration treatments on liver cancer and brain cancer.

scholarly journals Solution Selling in B2B: Perception of Solution Selling in Challenging Times of Management, Salesperson and Customers

2021 ◽  
Author(s):  
Guenther Maier
Keyword(s):  
Present Article ◽  
Scientific Literature ◽  
Present Review ◽  
Actual Situation ◽  
Leadership Position ◽  
Negative Effects ◽  
Extant Literature ◽  
Individual Perception ◽  
New Challenges ◽  
The Individual

Globalization and digitalization have yielded new challenges in the B2B sales environment. Besides positive also negative effects appeared in the last decades. Customer behaviour is becoming more complex, and the rivalry between the firms is getting more aggressive. Especially product-centred firms strive to fulfil their financial targets. The actual situation of COVID-19 amplify this situation. This new challenge entails firms and salespeople to find new resilient ways to survive and overcome crisis’s and resist the rivalry of competitors. The present article is based on the theoretical and extant literature of solution selling and customer solutions in different industries. Potential effects on solution selling will be discussed and contributed through empirical interviews with people in a leadership position in sales. This article analyses the individual perception of related stakeholders in B2B sales and will provide valuable insights on solution selling concerning their resilient attribute. This present review will contribute scholars on the existing literature and firms which are seeking for methods to distinct from competitors and to overcome crisis´s. Finally, the gaps in the scientific literature will be discussed for further research.

scholarly journals Pullulan for Advanced Sustainable Body- and Skin-Contact Applications

2020 ◽  
Vol 11 (1) ◽  
pp. 20 ◽  
Author(s):  
Maria-Beatrice Coltelli ◽  
Serena Danti ◽  
Karen De Clerck ◽  
Andrea Lazzeri ◽  
Pierfrancesco Morganti
Keyword(s):  
Present Review ◽  
Personal Care ◽  
Nano Technology ◽  
Microbial Polysaccharide ◽  
Skin Contact

The present review had the aim of describing the methodologies of synthesis and properties of biobased pullulan, a microbial polysaccharide investigated in the last decade because of its interesting potentialities in several applications. After describing the implications of pullulan in nano-technology, biodegradation, compatibility with body and skin, and sustainability, the current applications of pullulan are described, with the aim of assessing the potentialities of this biopolymer in the biomedical, personal care, and cosmetic sector, especially in applications in contact with skin.

scholarly journals Efficacy of hamstring stretching programs in schoolchildren. A systematic review

2015 ◽  
Vol 8 (15) ◽  
pp. 36-43
Author(s):  
Carlos-Alberto Becerra Fernandez ◽  
Rafael Merino-Marban
Keyword(s):  
Physical Education ◽  
Scientific Literature ◽  
Present Review ◽  
Physical Education Teachers ◽  
Inclusion Criteria ◽  
Control Groups ◽  
Warm Up ◽  
Detailed Evaluation ◽  
Hamstring Flexibility ◽  
Straight Leg Raise

Abstract The main purpose of the present review was to examine the scientific literature on the effects of physical education-based stretching programs on hamstring extensibility in schoolchildren aged 6-11 years. For this purpose relevant studies were searched from ten electronic databases dated up through May 2015. Of the 25 potentially relevant articles identified and retrieved for more detailed evaluation, only eight studies were included in the present review because they met the inclusion criteria. The overall results showed that incorporating hamstring stretching as a part of physical education classes produces a significant improvement in the scores of the tests: straight leg raise and classic sit-and-reach, for the experimental groups, but not for control groups. Stretching programs can be included in Physical Education classes, specifically during the warm-up and the cool down periods in order to improve hamstring extensibility. Although it seems that the stretching exercises in the warm-up period could be less effective in gaining flexibility in school children. Studies that use a stretching volume between 4 and 7 minutes per session and 2-4 training classes per week, obtain statistically significant improvements on the levels of hamstring flexibility in the experimental groups. However, after a five-week detraining period, children revert back to their initial flexibility levels. Therefore, it seems appropriate that physical education teachers should implement stretching programs to improve the students’ flexibility during the Physical Education classes.

scholarly journals Utilization of Eggshell Membrane and Olive Leaf Extract for the Preparation of Functional Materials

Foods ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 806
Author(s):  
Oguz Bayraktar ◽  
Charis M. Galanakis ◽  
Turki M. S. Aldawoud ◽  
Salam A. Ibrahim ◽  
Merve Deniz Köse ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Food Industry ◽  
Leaf Extract ◽  
Value Added ◽  
Functional Materials ◽  
Eggshell Membrane ◽  
Olive Leaf ◽  
Olive Leaf Extract ◽  
Antimicrobial Studies ◽  
Functional Biomaterials

Eggshell membrane (ESM) is a natural proteinaceous by-product of the food industry, especially in the pasteurized egg industry, resulting in the availability of much discarded egg waste. In the literature, eggshell (ES) and ESM usage for their adsorbent properties to remove various organic and inorganic hazardous chemicals, especially from wastewater, has gained interest. In addition, agricultural (olive leaf) and food industry (eggshell and eggshell membrane) waste can together be valorized to produce value-added functional products. This study’s objective was to evaluate the eggshell membrane’s loading capacity for bioactive compounds obtained from olive leaf extract (OLE) in order to prepare functional biomaterial. In this study, waste eggshell membranes were used to adsorb the phenolic compounds from olive leaf extract to design functional biomaterials. Using the foam separation method, both separation of the eggshell membrane and adsorption of bioactive compounds to the eggshell membrane were achieved simultaneously. The characterization studies showed that OLE was successfully adsorbed to the eggshell membrane. Cytotoxicity and antimicrobial studies showed that prepared OLE-loaded membranes were functional materials with bioactive properties. In conclusion, ESM was determined as a promising protein in the production of functional antioxidative and antimicrobial food or dietary supplement after the adsorption of bioactive olive leaf polyphenols.

scholarly journals Pseudomonas Infection of the Temporomandibular Joint (TMJ) Health and Public Health Issues

2017 ◽  
Vol 17 (1) ◽  
pp. 33-39 ◽  
Author(s):  
I. Malachovsky ◽  
M. Janickova ◽  
J. Stasko ◽  
M. Kasaj ◽  
V. Sadlonova ◽  
...  
Keyword(s):  
Public Health ◽  
Infectious Disease ◽  
Pseudomonas Aeruginosa ◽  
Temporomandibular Joint ◽  
Scientific Literature ◽  
Health Issues ◽  
Malignant External Otitis ◽  
Pseudomonas Infection ◽  
Microbial Agent

Abstract The authors describe a case of a rare infectious disease of intra-articular tissues of the temporomandibular joint caused mainly by Pseudomonas aeruginosa. In scientific literature, under the heading invasive (malignant) external otitis, we can find cases of an infectious disease of the external acoustic meatus caused by a microbial agent of Pseudomonas aeruginosa which can subsequently penetrate into structures. However, a primary affliction of the abovementioned structures has not been described. Localisation and severity of the infection requires long-term and massive treatment with antibiotics.

INFLUENCE OF MATERNAL CHORIOAMNIONITIS ON NEWBORNS MORBIDITY

2021 ◽  
Vol 100 (1) ◽  
pp. 75-83
Author(s):  
E.A. Shevareva ◽  
◽  
D.O. Ivanov ◽  
O.V. Nevmerzhitskaia ◽  
L.A. Fedorova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
Scientific Literature ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Neonatal Morbidity ◽  
Current Data ◽  
Present Review ◽  
Intraamniotic Infection

In recent decades, the problem of chorioamnionitis (CA) (or intra-amniotic infection) takes a leading place in modern obstetrics and perinatology. It is known that CA is one of the main risk factors for preterm birth and increases neonatal morbidity. Intraamniotic infection is a polyetiology condition. It is characterised by the variety of clinical manifestations absence of clearly association between the infection`s clinical signs in mother and infants injury. In present review we defined current data about chorioamnionitis, based on the last evidence of international scientific literature.

scholarly journals A descriptive review on patient medication history interview

2021 ◽  
pp. 01-04
Author(s):  
L Vinay Sai ◽  
Venkata Ramana ◽  
K Mamatha ◽  
D Saritha ◽  
Jerusha Evagelin ◽  
...  
Keyword(s):  
Scientific Literature ◽  
Practical Approach ◽  
Present Review ◽  
Pictorial Representation ◽  
Medication History ◽  
Patient Medication ◽  
Effective Manner ◽  
Drug History

The Present descriptive review provides a detailed practical approach in conducting the effective patient medication interview. It includes four main areas, 1) the process involved and goals to be achieved, 2) the importance of accurate patient drug history in patient medication history interview, 3) information to be recorded during patient medication history interview and 4) how to conduct patient medication interview in an effective manner. This present review further attempted to give a clear pictorial representation regarding patient medication history interview as well produced a well-documented patient medication history interview form by referring all the available sources and thorough review of all available scientific literature.

scholarly journals Identification and biochemical characterisation of tyrosine aminotransferase from Anthoceros agrestis unveils the conceivable entry point into rosmarinic acid biosynthesis in hornworts

Planta ◽  
2021 ◽  
Vol 253 (5) ◽  
Author(s):  
Tobias Busch ◽  
Maike Petersen
Keyword(s):  
Rosmarinic Acid ◽  
Model Organism ◽  
Initial Step ◽  
Tyrosine Aminotransferase ◽  
Terrestrial Plants ◽  
Acid Biosynthesis ◽  
E Coli ◽  
Biochemical Characterisation ◽  
Wide Range ◽  
Amino Donor

Abstract Main conclusion Tyrosine aminotransferase (AaTAT) from the hornwort Anthoceros agrestis Paton (Anthocerotaceae) was amplified and expressed in E. coli. The active enzyme is able to accept a wide range of substrates with distinct preference for l-tyrosine, therefore, possibly catalysing the initial step in rosmarinic acid biosynthesis. Abstract The presence of rosmarinic acid (RA) in the hornwort A. agrestis is well known, and some attempts have been made to clarify the biosynthesis of this caffeic acid ester in lower plants. Parallel to the biosynthesis in vascular plants, the involvement of tyrosine aminotransferase (EC 2.6.1.5; TAT) as the initial step was assumed. The amplification of a nucleotide sequence putatively encoding AaTAT (Genbank MN922307) and expression in E. coli were successful. The enzyme proved to have a high acceptance of l-tyrosine (Km 0.53 mM) whilst slightly preferring 2-oxoglutarate over phenylpyruvate as co-substrate. Applying l-phenylalanine as a potential amino donor or using oxaloacetate or pyruvate as a replacement for 2-oxoglutarate as amino acceptor resulted in significantly lower catalytic efficiencies in each of these cases. To facilitate further substrate search, two methods were introduced, one using ninhydrin after thin-layer chromatography and the other using derivatisation with o-phthalaldehyde followed by HPLC or LC–MS analysis. Both methods proved to be well applicable and helped to confirm the acceptance of further aromatic and aliphatic amino acids. This work presents the first description of a heterologously expressed TAT from a hornwort (A. agrestis) and describes the possible entry into the biosynthesis of RA and other specialised compounds in a so far neglected representative of terrestrial plants and upcoming new model organism.

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