scholarly journals The Interventricular Septum Is Biomechanically Distinct from the Ventricular Free Walls

2021 ◽  
Vol 8 (12) ◽  
pp. 216
Author(s):  
Michael Nguyen-Truong ◽  
Wenqiang Liu ◽  
Courtney Doherty ◽  
Kristen LeBar ◽  
Kevin Labus ◽  
...  

The interventricular septum contributes to the pumping function of both ventricles. However, unlike the ventricular wall, its mechanical behavior remains largely unknown. To fill the knowledge gap, this study aims to characterize the biaxial and transmural variation of the mechanical properties of the septum and compare it to the free walls of the left and right ventricles (LV/RV). Fresh hearts were obtained from healthy, adult sheep. The septal wall was sliced along the mid-line into two septal sides and compared to the epicardial layers of the LV- and RV-free walls. Biaxial tensile mechanical tests and constitutive modeling were performed to obtain the passive mechanical properties of the LV- and RV-side of the septum and ventricular walls. We found that both sides of the septum were significantly softer than the respective ventricular walls, and that the septum presented significantly less collagen than the ventricular walls. At low strains, we observed the symmetric distribution of the fiber orientations and a similar anisotropic behavior between the LV-side and RV-side of the septum, with a stiffer material property in the longitudinal direction, rather than the circumferential direction. At high strains, both sides showed isotropic behavior. Both septal sides had similar intrinsic elasticity, as evidenced by experimental data and constitutive modeling. These new findings offer important knowledge of the biomechanics of the septum wall, which may deepen the understanding of heart physiology.

Author(s):  
Wenqiang Liu ◽  
Michael Nguyen-Truong ◽  
Matt Ahern ◽  
Kevin Labus ◽  
Christian Puttlitz ◽  
...  

Abstract Ventricle dysfunction is the most common cause of heart failure, which leads to high mortality and morbidity. The mechanical behavior of the ventricle is critical to its physiological function. It is known that the ventricle is anisotropic and viscoelastic. However, the understanding of ventricular viscoelasticity is much less than that of its elasticity. Moreover, the left and right ventricles (LV&RV) are different in embryologic origin, anatomy, and function, but whether they distinguish in viscoelastic properties is unclear. We hypothesized that passive viscoelasticity is different between healthy LVs and RVs. Ex vivo cyclic biaxial tensile mechanical tests (1, 0.1, 0.01Hz) and stress relaxation (strain of 3, 6, 9, 12 15%) were performed for ventricles from healthy adult sheep. Outflow track direction was defined as the longitudinal direction. Hysteresis stress-strain loops and stress relaxation curves were obtained to quantify the viscoelastic properties. We found that the RV had more pronounced frequency-dependent viscoelastic changes than the LV. Under the physiological frequency (1Hz), the LV was more anisotropic in the elasticity and stiffer than the RV in both directions, whereas the RV was more anisotropic in the viscosity and more viscous than the LV in the longitudinal direction. The LV was quasi-linear viscoelastic in the longitudinal but not circumferential direction, and the RV was non-linear viscoelastic in both directions. This study is the first to investigate passive viscoelastic differences in healthy LVs and RVs, and the findings will deepen the understanding of biomechanical mechanisms of ventricular function.


2019 ◽  
Vol 14 (1) ◽  
pp. 110
Author(s):  
Assiss. Prof. Dr. Sabiha Mahdi Mahdi ◽  
Dr. Firas Abd K. Abd K.

Aim: The aimed study was to evaluate the influence of silver nitrate on surfacehardness and tensile strength of acrylic resins.Materials and methods: A total of 60 specimens were made from heat polymerizingresins. Two mechanical tests were utilized (surface hardness and tensile strength)and 4 experimental groups according to the concentration of silver nitrate used.The specimens without the use of silver nitrate were considered as control. Fortensile strength, all specimens were subjected to force till fracture. For surfacehardness, the specimens were tested via a durometer hardness tester. Allspecimens data were analyzed via ANOVA and Tukey tests.Results: The addition of silver nitrate to acrylic resins reduced significantly thetensile strength. Statistically, highly significant differences were found among allgroups (P≤0.001). Also, the difference between control and experimental groupswas highly significant (P≤0.001). For surface hardness, the silver nitrate improvedthe surface hardness of acrylics. Highly significant differences were statisticallyobserved between control and 900 ppm group (P≤0.001); and among all groups(P≤0.001)with exception that no significant differences between control and150ppm; and between 150ppm and 900ppm groups(P>0.05).Conclusion: The addition of silver nitrate to acrylics reduced significantly the tensilestrength and improved slightly the surface hardness.


Author(s):  
Georgel MIHU ◽  
Claudia Veronica UNGUREANU ◽  
Vasile BRIA ◽  
Marina BUNEA ◽  
Rodica CHIHAI PEȚU ◽  
...  

Epoxy resins have been presenting a lot of scientific and technical interests and organic modified epoxy resins have recently receiving a great deal of attention. For obtaining the composite materials with good mechanical proprieties, a large variety of organic modification agents were used. For this study gluten and gelatin had been used as modifying agents thinking that their dispersion inside the polymer could increase the polymer biocompatibility. Equal amounts of the proteins were milled together and the obtained compound was used to form 1 to 5% weight ratios organic agents modified epoxy materials. To highlight the effect of these proteins in epoxy matrix mechanical tests as three-point bending and compression were performed.


Micromachines ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 293
Author(s):  
José M. Acosta-Cuevas ◽  
José González-García ◽  
Mario García-Ramírez ◽  
Víctor H. Pérez-Luna ◽  
Erick Omar Cisneros-López ◽  
...  

Photopolymerized microparticles are made of biocompatible hydrogels like Polyethylene Glycol Diacrylate (PEGDA) by using microfluidic devices are a good option for encapsulation, transport and retention of biological or toxic agents. Due to the different applications of these microparticles, it is important to investigate the formulation and the mechanical properties of the material of which they are made of. Therefore, in the present study, mechanical tests were carried out to determine the swelling, drying, soluble fraction, compression, cross-linking density (Mc) and mesh size (ξ) properties of different hydrogel formulations. Tests provided sufficient data to select the best formulation for the future generation of microparticles using microfluidic devices. The initial gelation times of the hydrogels formulations were estimated for their use in the photopolymerization process inside a microfluidic device. Obtained results showed a close relationship between the amount of PEGDA used in the hydrogel and its mechanical properties as well as its initial gelation time. Consequently, it is of considerable importance to know the mechanical properties of the hydrogels made in this research for their proper manipulation and application. On the other hand, the initial gelation time is crucial in photopolymerizable hydrogels and their use in continuous systems such as microfluidic devices.


Author(s):  
Fulufhelo Nemavhola

AbstractRegional mechanics of the heart is vital in the development of accurate computational models for the pursuit of relevant therapies. Challenges related to heart dysfunctioning are the most important sources of mortality in the world. For example, myocardial infarction (MI) is the foremost killer in sub-Saharan African countries. Mechanical characterisation plays an important role in achieving accurate material behaviour. Material behaviour and constitutive modelling are essential for accurate development of computational models. The biaxial test data was utilised to generated Fung constitutive model material parameters of specific region of the pig myocardium. Also, Choi-Vito constitutive model material parameters were also determined in various myocardia regions. In most cases previously, the mechanical properties of the heart myocardium were assumed to be homogeneous. Most of the computational models developed have assumed that the all three heart regions exhibit similar mechanical properties. Hence, the main objective of this paper is to determine the mechanical material properties of healthy porcine myocardium in three regions, namely left ventricle (LV), mid-wall/interventricular septum (MDW) and right ventricle (RV). The biomechanical properties of the pig heart RV, LV and MDW were characterised using biaxial testing. The biaxial tests show the pig heart myocardium behaves non-linearly, heterogeneously and anisotropically. In this study, it was shown that RV, LV and MDW may exhibit slightly different mechanical properties. Material parameters of two selected constitutive models here may be helpful in regional tissue mechanics, especially for the understanding of various heart diseases and development of new therapies.


Forests ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 567
Author(s):  
Hong Yang ◽  
Mingyu Gao ◽  
Jinxin Wang ◽  
Hongbo Mu ◽  
Dawei Qi

In the absence of high-quality hardwood timber resources, we have gradually turned our attention from natural forests to planted fast-growing forests. However, fast-growing tree timber in general has defects such as low wood density, loose texture, and poor mechanical properties. Therefore, improving the performance of wood through efficient and rapid technological processes and increasing the utilization of inferior wood is a good way to extend the use of wood. Densification of wood increases the strength of low-density wood and extends the range of applications for wood and wood-derived products. In this paper, the effects of ultrasonic and vacuum pretreatment on the properties of high-performance wood were explored by combining sonication, vacuum impregnation, chemical softening, and thermomechanical treatments to densify the wood; then, the changes in the chemical composition, microstructure, and mechanical properties of poplar wood before and after treatment were analyzed comparatively by FT-IR, XRD, SEM, and mechanical tests. The results showed that with ultrasonic pretreatment and vacuum impregnation, the compression ratio of high-performance wood reached its highest level and the MOR and MOE reached their maximums. With the help of this method, fast-growing softwoods can be easily prepared into dense wood materials, and it is hoped that this new material can be applied in the fields of construction, aviation, and automobile manufacturing.


Author(s):  
Kadir Özkaya ◽  
Taner Dizel ◽  
Hasan Özgür Imirzi

The amount of waste produced by people increases with the increasing population in the world. Especially non-recyclable wastes have become a major environmental problem. Waste tires that emerge as car demands of people increase are one of the non-recyclable wastes. In this study, the usage possibilities of powder rubbers obtained from waste car tires were examined in the production of laminated veneer lumber (LVL) boards, which are preferred as furniture and decoration material in the forest products industry. For this, three different tree species (Scotch Pine— Pinus silvestris L., Oriental Beech— Fagus orientalis L., Stinking Juniper— Juniperus foetidissima Wild.) and two different types of glue (UF and PVAc glues) were used. Waste tire rubbers (WTR) were mixed into the glue in different proportions (0%, 10%, 20%, 30%). Physical (full dry and equilibrium moisture density, contraction in the transversal and longitudinal direction) and mechanical tests (MoR, MoE, bonding resistance) were performed on the LVL samples prepared. According to the results obtained, it has been seen that the mixtures of 10% and 20% WTR increase the LVL resistance. An eco-friendly building material has been obtained by using WTR produced from waste car tires in production of LVL.


2015 ◽  
Vol 35 (3) ◽  
pp. 257-266 ◽  
Author(s):  
Rahim Eqra ◽  
Kamal Janghorban ◽  
Habib Daneshmanesh

Abstract Because of extraordinary physical, chemical and mechanical properties, graphene nanosheets (GNS) are suitable fillers for optimizing the properties of different polymers. In this research, the effect of GNS content (up to 1 wt.%) on tensile and flexural properties, morphology of fracture surface, and toughening mechanism of epoxy were investigated. Results of mechanical tests showed a peak for tensile and flexural strength of samples with 0.1 wt.% GNS such that the tensile and flexural strength improved by 13% and 3.3%, respectively. The Young’s modulus and flexural modulus increased linearly with GNS content, although the behavior of the Young’s modulus was more remarkable. Morphological investigations confirmed this behavior because the GNS dispersion in the epoxy matrix was uniform at lower contents and agglomerated at higher contents. Finally, microscopical observation showed that the major toughening mechanism of graphene-epoxy nanocomposites was crack path deflection, which changed the mirror fracture surface of the pure epoxy to rough surface.


Author(s):  
Guillaume Chas ◽  
Nathalie Rupa ◽  
Josseline Bourgoin ◽  
Astrid Hotellier ◽  
Se´bastien Saillet

By monitoring the irradiation-induced embrittlement of materials, the Pressure Vessel Surveillance Program (PVSP) contributes to the RPV integrity and lifetime assessments. This program is implemented on each PWR Unit in France; it is mainly based on Charpy tests, which are widely used in the nuclear industry to characterize the mechanical properties of the materials. Moreover, toughness tests are also carried out to check the conservatism of the PVSP methodology. This paper first describes the procedure followed for the Pressure Vessel Surveillance Program. It presents the irradiation capsules: the samples materials (low alloy Mn, Ni, Mo vessel steel including base metals, heat affected zones, welds and a reference material) and the mechanical tests performed. Then it draws up a synthesis of the analysis of about 180 capsules removed from the reactors at fluence levels up to 7.1019 n/cm2 (E > 1 MeV). This database gathers the results of more than 10,000 Charpy tests and 250 toughness tests. The experimental results confirm the conservatism of the Code-based methodology applied to the toughness assessment.


2021 ◽  
Vol 891 ◽  
pp. 150-163
Author(s):  
Jorge Mauricio Fuentes ◽  
Omar Flor Unda ◽  
Santiago Ferrandiz ◽  
Franyelit Suarez

In this article presents evidence about performance of mechanical properties of polycarbonate and nylon materials, which are used in the additive manufacturing by deposition of molten material and that have been subjected to sterilization processes by moist heat at 121°C and dry heat at 140°C. This study provides useful information to consider the use of these materials in sanitary and sterile settings. Mechanical tests of tensile, flex, hardness, Izod impact, thermal tests in Differential Scanning Calorimetry DSC, Thermomechanical analysis TMA and Scanning Electron Microscopy SEM were performed. It is concluded that the mechanical and thermal properties have not been altered through the effect of temperature in sterilization processes.


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