scholarly journals Translational Applications of Artificial Intelligence and Machine Learning for Diagnostic Pathology in Lymphoid Neoplasms: A Comprehensive and Evolutive Analysis

Biomolecules ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 793
Author(s):  
Julia Moran-Sanchez ◽  
Antonio Santisteban-Espejo ◽  
Miguel Angel Martin-Piedra ◽  
Jose Perez-Requena ◽  
Marcial Garcia-Rojo
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Genomic Analysis ◽  
Prognostic Models ◽  
Chemotherapy Response ◽  
Learning Tools ◽  
Global Trends ◽  
Research Areas ◽  
Lymphoid Neoplasms ◽  
The Usa

Genomic analysis and digitalization of medical records have led to a big data scenario within hematopathology. Artificial intelligence and machine learning tools are increasingly used to integrate clinical, histopathological, and genomic data in lymphoid neoplasms. In this study, we identified global trends, cognitive, and social framework of this field from 1990 to 2020. Metadata were obtained from the Clarivate Analytics Web of Science database in January 2021. A total of 525 documents were assessed by document type, research areas, source titles, organizations, and countries. SciMAT and VOSviewer package were used to perform scientific mapping analysis. Geographical distribution showed the USA and People’s Republic of China as the most productive countries, reporting up to 190 (36.19%) of all documents. A third-degree polynomic equation predicts that future global production in this area will be three-fold the current number, near 2031. Thematically, current research is focused on the integration of digital image analysis and genomic sequencing in Non-Hodgkin lymphomas, prediction of chemotherapy response and validation of new prognostic models. These findings can serve pathology departments to depict future clinical and research avenues, but also, public institutions and administrations to promote synergies and optimize funding allocation.

scholarly journals Artificial Intelligence, Machine Learning and Deep Learning in Ion Channel Bioinformatics

Membranes ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 672
Author(s):  
Md. Ashrafuzzaman
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Ion Channels ◽  
Ion Channel ◽  
Research Trend ◽  
Cellular Processes ◽  
Research Areas ◽  
Huge Data ◽  
Functional Aspects

Ion channels are linked to important cellular processes. For more than half a century, we have been learning various structural and functional aspects of ion channels using biological, physiological, biochemical, and biophysical principles and techniques. In recent days, bioinformaticians and biophysicists having the necessary expertise and interests in computer science techniques including versatile algorithms have started covering a multitude of physiological aspects including especially evolution, mutations, and genomics of functional channels and channel subunits. In these focused research areas, the use of artificial intelligence (AI), machine learning (ML), and deep learning (DL) algorithms and associated models have been found very popular. With the help of available articles and information, this review provide an introduction to this novel research trend. Ion channel understanding is usually made considering the structural and functional perspectives, gating mechanisms, transport properties, channel protein mutations, etc. Focused research on ion channels and related findings over many decades accumulated huge data which may be utilized in a specialized scientific manner to fast conclude pinpointed aspects of channels. AI, ML, and DL techniques and models may appear as helping tools. This review aims at explaining the ways we may use the bioinformatics techniques and thus draw a few lines across the avenue to let the ion channel features appear clearer.

A Survey on Intelligence Tools for Data Analytics

2021 ◽  
pp. 73-95
Author(s):  
Shatakshi Singh ◽  
Kanika Gautam ◽  
Prachi Singhal ◽  
Sunil Kumar Jangir ◽  
Manish Kumar
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Language Processing ◽  
Real Life ◽  
Learning Tools ◽  
The Core ◽  
Training Mode ◽  
Real Life Situation ◽  
Selection Of

The recent development in artificial intelligence is quite astounding in this decade. Especially, machine learning is one of the core subareas of AI. Also, ML field is an incessantly growing along with evolution and becomes a rise in its demand and importance. It transmogrified the way data is extracted, analyzed, and interpreted. Computers are trained to get in a self-training mode so that when new data is fed they can learn, grow, change, and develop themselves without explicit programming. It helps to make useful predictions that can guide better decisions in a real-life situation without human interference. Selection of ML tool is always a challenging task, since choosing an appropriate tool can end up saving time as well as making it faster and easier to provide any solution. This chapter provides a classification of various machine learning tools on the following aspects: for non-programmers, for model deployment, for Computer vision, natural language processing, and audio for reinforcement learning and data mining.

Rule Generation Methods Based on Logic Synthesis

2011 ◽  
pp. 978-983
Author(s):  
Marco Muselli
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Neural Networks ◽  
Real World ◽  
Inductive Reasoning ◽  
Logic Synthesis ◽  
Rule Generation ◽  
Research Areas ◽  
Real World Problem

One of the most relevant problems in artificial intelligence is allowing a synthetic device to perform inductive reasoning, i.e. to infer a set of rules consistent with a collection of data pertaining to a given real world problem. A variety of approaches, arising in different research areas such as statistics, machine learning, neural networks, etc., have been proposed during the last 50 years to deal with the problem of realizing inductive reasoning.

scholarly journals Machine learning challenges and impact: an interview with Thomas Dietterich

2017 ◽  
Vol 5 (1) ◽  
pp. 54-58 ◽  
Author(s):  
Zhi-Hua Zhou
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Driving Force ◽  
Professor Emeritus ◽  
State University ◽  
Learning Society ◽  
Learning Challenges ◽  
The World ◽  
The Usa ◽  
Oregon State University

Abstract Machine learning is the driving force of the hot artificial intelligence (AI) wave. In an interview with NSR, Prof. Thomas Dietterich, the distinguished professor emeritus of computer science at Oregon State University in the USA, the former president of Association of Advancement of Artificial Intelligence (AAAI, the most prestigious association in the field of artificial intelligence) and the founding president of the International Machine Learning Society, talked about exciting recent advances and technical challenges of machine learning, as well as its big impact on the world.

scholarly journals Automated Reasoning for Explainable Artificial Intelligence

10.29007/4b7h ◽  
2018 ◽  
Author(s):  
Maria Paola Bonacina
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Automated Reasoning ◽  
Position Statement ◽  
Short Paper ◽  
Future Research ◽  
Grand Challenge ◽  
New Paradigm ◽  
Research Areas ◽  
Explainable Artificial Intelligence

Reasoning and learning have been considered fundamental features of intelligence ever since the dawn of the field of artificial intelligence, leading to the development of the research areas of automated reasoning and machine learning. This short paper is a non-technical position statement that aims at prompting a discussion of the relationship between automated reasoning and machine learning, and more generally between automated reasoning and artificial intelligence. We suggest that the emergence of the new paradigm of XAI, that stands for eXplainable Artificial Intelligence, is an opportunity for rethinking these relationships, and that XAI may offer a grand challenge for future research on automated reasoning.

scholarly journals Machine learning forecasting of USA and PRC balance of trade in context of mutual sanctions

2020 ◽  
Vol 73 ◽  
pp. 01025
Author(s):  
Zuzana Rowland ◽  
Jaromír Vrbka ◽  
Marek Vochozka
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Time Series ◽  
Multilayer Perceptron ◽  
Traded Goods ◽  
Suitable Tool ◽  
The Usa ◽  
Balance Of Trade ◽  
Trade War ◽  
Multilayer Perceptron Networks

The USA decided to regulate the trade more by imposing tariffs on specific types of traded goods. It is therefore more interesting to find out whether the current technologies based on artificial intelligence with time series influenced by extraordinary factors such as the trade war between two powers are able to work. The objective of the contribution is to examine and subsequently equalize two time series – the USA import from the PRC and the USA export to the PRC. The dataset shows the course of the time series at monthly intervals between January 2000 and July 2019. 10,000 multilayer perceptron networks (MLP) are generated, out of which 5 with the best characteristics are retained. It has been proved that multilayer perceptron networks are a suitable tool for forecasting the development of the time series if there are no sudden fluctuations. Mutual sanctions of both states did not affect the result of machine learning forecasting.

scholarly journals Characterizing Artificial Intelligence Applications in Cancer Research using Latent Dirichlet Allocation (Preprint)

2019 ◽  
Author(s):  
Bach Xuan Tran ◽  
Carl A. Latkin ◽  
Noha Sharafeldin ◽  
Katherina Nguyen ◽  
Giang Thu Vu ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Cancer Research ◽  
Latent Dirichlet Allocation ◽  
Similarity Index ◽  
Cancer Control ◽  
Clinical Practices ◽  
Global Trends ◽  
Patient Reported ◽  
Dirichlet Allocation

BACKGROUND Artificial Intelligence (AI) - based therapeutics, devices and systems are vital innovations in cancer control. OBJECTIVE This study analyzes the global trends, patterns, and development of interdisciplinary landscapes in AI and cancer research. METHODS Exploratory factor analysis was applied to identify research domains emerging from contents of the abstracts. Jaccard’s similarity index was utilized to identify terms most frequently co-occurring with each other. Latent Dirichlet Allocation was used for classifying papers into corresponding topics. RESULTS The number of studies applying AI to cancer during 1991-2018 has been grown with 3,555 papers covering therapeutics, capacities, and factors associated with outcomes. Topics with the highest volumes of publications include 1) Machine learning, 2) Comparative Effectiveness Evaluation of AI-assisted medical therapies, 3) AI-based Prediction. Noticeably, this classification has revealed topics examining the incremental effectiveness of AI applications, the quality of life and functioning of patients receiving these innovations. The growing research productivity and expansion of multidisciplinary approaches, largely driven by machine learning, artificial neutral network, and artificial intelligence in various clinical practices. CONCLUSIONS The research landscapes show that the development of AI in cancer is focused not only on improving prediction in cancer screening and AI-assisted therapeutics, but also other corresponding areas such as Precision and Personalized Medicine and patient-reported outcomes.

scholarly journals Global Trends in Cancer Nanotechnology: A Qualitative Scientific Mapping Using Content-Based and Bibliometric Features for Machine Learning Text Classification

Cancers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 4417
Author(s):  
Nuwan Indika Millagaha Gedara ◽  
Xuan Xu ◽  
Robert DeLong ◽  
Santosh Aryal ◽  
Majid Jaberi-Douraki
Keyword(s):  
Machine Learning ◽  
Qualitative Method ◽  
Research Topics ◽  
Global Trends ◽  
Nanotechnology Research ◽  
Pubmed Database ◽  
The Usa ◽  
Cancer Nanotechnology ◽  
Current Lines ◽  
The Uk

This study presents a new way to investigate comprehensive trends in cancer nanotechnology research in different countries, institutions, and journals providing critical insights to prevention, diagnosis, and therapy. This paper applied the qualitative method of bibliometric analysis on cancer nanotechnology using the PubMed database during the years 2000–2021. Inspired by hybrid medical models and content-based and bibliometric features for machine learning models, our results show cancer nanotechnology studies have expanded exponentially since 2010. The highest production of articles in cancer nanotechnology is mainly from US institutions, with several countries, notably the USA, China, the UK, India, and Iran as concentrated focal points as centers of cancer nanotechnology research, especially in the last five years. The analysis shows the greatest overlap between nanotechnology and DNA, RNA, iron oxide or mesoporous silica, breast cancer, and cancer diagnosis and cancer treatment. Moreover, more than 50% of the information related to the keywords, authors, institutions, journals, and countries are considerably investigated in the form of publications from the top 100 journals. This study has the potential to provide past and current lines of research that can unmask comprehensive trends in cancer nanotechnology, key research topics, or the most productive countries and authors in the field.

scholarly journals Application of Deep Q-learning and double Deep Q-learning algorithms to the task of control an inverted pendulum

2020 ◽  
pp. 7-25
Author(s):  
Alla Evseenko ◽  
◽  
Dmitrii Romannikov ◽  
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Reinforcement Learning ◽  
Inverted Pendulum ◽  
Learning Algorithm ◽  
Learning Algorithms ◽  
Training Time ◽  
Q Learning ◽  
Research Areas ◽  
Wide Range

Today, such a branch of science as «artificial intelligence» is booming in the world. Systems built on the basis of artificial intelligence methods have the ability to perform functions that are traditionally considered the prerogative of man. Artificial intelligence has a wide range of research areas. One such area is machine learning. This article discusses the algorithms of one of the approaches of machine learning – reinforcement learning (RL), according to which a lot of research and development has been carried out over the past seven years. Development and research on this approach is mainly carried out to solve problems in Atari 2600 games or in other similar ones. In this article, reinforcement training will be applied to one of the dynamic objects – an inverted pendulum. As a model of this object, we consider a model of an inverted pendulum on a cart taken from the Gym library, which contains many models that are used to test and analyze reinforcement learning algorithms. The article describes the implementation and study of two algorithms from this approach, Deep Q-learning and Double Deep Q-learning. As a result, training, testing and training time graphs for each algorithm are presented, on the basis of which it is concluded that it is desirable to use the Double Deep Q-learning algorithm, because the training time is approximately 2 minutes and provides the best control for the model of an inverted pendulum on a cart.

scholarly journals Potential of artificial intelligence to accelerate diagnosis and drug discovery for COVID-19

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e12073
Author(s):  
Indira Mikkili ◽  
Abraham Peele Karlapudi ◽  
T. C. Venkateswarulu ◽  
Vidya Prabhakar Kodali ◽  
Deepika Sri Singh Macamdas ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Imaging Techniques ◽  
Learning Tools ◽  
Rt Pcr ◽  
Drug Molecules ◽  
Potential Applications ◽  
The Neural Networks ◽  
Polymerase Chain ◽  
The Internet Of Things

The coronavirus disease (COVID-19) pandemic has caused havoc worldwide. The tests currently used to diagnose COVID-19 are based on real time reverse transcription polymerase chain reaction (RT-PCR), computed tomography medical imaging techniques and immunoassays. It takes 2 days to obtain results from the RT-PCR test and also shortage of test kits creating a requirement for alternate and rapid methods to accurately diagnose COVID-19. Application of artificial intelligence technologies such as the Internet of Things, machine learning tools and big data analysis to COVID-19 diagnosis could yield rapid and accurate results. The neural networks and machine learning tools can also be used to develop potential drug molecules. Pharmaceutical companies face challenges linked to the costs of drug molecules, research and development efforts, reduced efficiency of drugs, safety concerns and the conduct of clinical trials. In this review, relevant features of artificial intelligence and their potential applications in COVID-19 diagnosis and drug development are highlighted.

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